#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P59633 uniprotkb:Q01196-1 intact:EBI-25489004|uniprotkb:Q7TFA9|uniprotkb:Q80BV4 intact:EBI-925940|ensembl:ENSP00000340690 psi-mi:ns3b_sars(display_long)|uniprotkb:Accessory protein 3b(gene name synonym)|uniprotkb:Protein X2(gene name synonym)|uniprotkb:3b(orf name)|uniprotkb:Non-structural protein 3b(gene name synonym) psi-mi:q01196-1(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym) psi-mi:"MI:0018"(two hybrid) Varshney et al. (2011) pubmed:22253733|imex:IM-28066 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25641791|imex:IM-28066-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001817"(regulation of cytokine production)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR022117|refseq:NP_828853.1 intact:EBI-925904(runx1_human)|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript) - - - figure legend:Fig. 1A|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/06/10 2020/06/10 rogid:EXisl4V+/e8ZhnQTLu6kcdKi4RE694009 rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606 rigid:5TXe/sUqo0/Z4Udu41SxeHkWSrg false - sufficient binding region:51-421 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01196-1 uniprotkb:P59633 intact:EBI-925940|ensembl:ENSP00000340690 intact:EBI-25489004|uniprotkb:Q7TFA9|uniprotkb:Q80BV4 psi-mi:q01196-1(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym) psi-mi:ns3b_sars(display_long)|uniprotkb:Accessory protein 3b(gene name synonym)|uniprotkb:Protein X2(gene name synonym)|uniprotkb:3b(orf name)|uniprotkb:Non-structural protein 3b(gene name synonym) psi-mi:"MI:0018"(two hybrid) Varshney et al. (2011) pubmed:22253733|imex:IM-28066 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25641816|imex:IM-28066-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-925904(runx1_human)|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript) go:"GO:0001817"(regulation of cytokine production)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR022117|refseq:NP_828853.1 - - - figure legend:Fig. 1b|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/06/10 2020/06/10 rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606 rogid:EXisl4V+/e8ZhnQTLu6kcdKi4RE694009 rigid:5TXe/sUqo0/Z4Udu41SxeHkWSrg false sufficient binding region:51-421 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P59633 uniprotkb:Q01196-1 intact:EBI-25489004|uniprotkb:Q7TFA9|uniprotkb:Q80BV4 intact:EBI-925940|ensembl:ENSP00000340690 psi-mi:ns3b_sars(display_long)|uniprotkb:Accessory protein 3b(gene name synonym)|uniprotkb:Protein X2(gene name synonym)|uniprotkb:3b(orf name)|uniprotkb:Non-structural protein 3b(gene name synonym) psi-mi:q01196-1(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Varshney et al. (2011) pubmed:22253733|imex:IM-28066 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25641966|imex:IM-28066-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001817"(regulation of cytokine production)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR022117|refseq:NP_828853.1 intact:EBI-925904(runx1_human)|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript) - - - figure legend:Fig. 1c|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/10 2020/06/22 rogid:EXisl4V+/e8ZhnQTLu6kcdKi4RE694009 rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606 rigid:5TXe/sUqo0/Z4Udu41SxeHkWSrg false 35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q01196-1 uniprotkb:P59633 intact:EBI-925940|ensembl:ENSP00000340690 intact:EBI-25489004|uniprotkb:Q7TFA9|uniprotkb:Q80BV4 psi-mi:q01196-1(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym) psi-mi:ns3b_sars(display_long)|uniprotkb:Accessory protein 3b(gene name synonym)|uniprotkb:Protein X2(gene name synonym)|uniprotkb:3b(orf name)|uniprotkb:Non-structural protein 3b(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Varshney et al. (2011) pubmed:22253733|imex:IM-28066 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25641984|imex:IM-28066-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-925904(runx1_human)|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript) go:"GO:0001817"(regulation of cytokine production)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR022117|refseq:NP_828853.1 - - - figure legend:Fig. 1d panel 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2020/06/10 2020/06/11 rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606 rogid:EXisl4V+/e8ZhnQTLu6kcdKi4RE694009 rigid:5TXe/sUqo0/Z4Udu41SxeHkWSrg false flag tag:n-n myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q01196-1 uniprotkb:P59633 intact:EBI-925940|ensembl:ENSP00000340690 intact:EBI-25489004|uniprotkb:Q7TFA9|uniprotkb:Q80BV4 psi-mi:q01196-1(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym) psi-mi:ns3b_sars(display_long)|uniprotkb:Accessory protein 3b(gene name synonym)|uniprotkb:Protein X2(gene name synonym)|uniprotkb:3b(orf name)|uniprotkb:Non-structural protein 3b(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Varshney et al. (2011) pubmed:22253733|imex:IM-28066 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25641992|imex:IM-28066-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-925904(runx1_human)|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript) go:"GO:0001817"(regulation of cytokine production)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR022117|refseq:NP_828853.1 - - - figure legend:Fig. 1d panel 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2020/06/10 2020/06/11 rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606 rogid:EXisl4V+/e8ZhnQTLu6kcdKi4RE694009 rigid:5TXe/sUqo0/Z4Udu41SxeHkWSrg false flag tag:n-n enhanced green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q01196-1 uniprotkb:P59633 intact:EBI-925940|ensembl:ENSP00000340690 intact:EBI-25489004|uniprotkb:Q7TFA9|uniprotkb:Q80BV4 psi-mi:q01196-1(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym) psi-mi:ns3b_sars(display_long)|uniprotkb:Accessory protein 3b(gene name synonym)|uniprotkb:Protein X2(gene name synonym)|uniprotkb:3b(orf name)|uniprotkb:Non-structural protein 3b(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Varshney et al. (2011) pubmed:22253733|imex:IM-28066 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25642010|imex:IM-28066-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-925904(runx1_human)|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript) go:"GO:0001817"(regulation of cytokine production)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR022117|refseq:NP_828853.1 go:"GO:0005634"(nucleus) - - figure legend:Fig. 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/06/10 2020/06/11 rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606 rogid:EXisl4V+/e8ZhnQTLu6kcdKi4RE694009 rigid:5TXe/sUqo0/Z4Udu41SxeHkWSrg false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) ensembl:ENSG00000109471 uniprotkb:Q01196-1 intact:EBI-1566859 intact:EBI-925940|ensembl:ENSP00000340690 uniprotkb:IL2(gene name)|psi-mi:IL2(display_short)|ensembl:il2_human_gene(shortlabel)|psi-mi:ENSG00000109471(display_long) psi-mi:q01196-1(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Varshney et al. (2011) pubmed:22253733|imex:IM-28066 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25642030|imex:IM-28066-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) refseq:NP_000577.2 intact:EBI-925904(runx1_human)|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript) - - - figure legend:Fig. 3-1|stimulant:"SRAS-CoV 3b protein (UniProt:P59633)"|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jurkat)|taxid:9606(Homo sapiens) - 2020/06/10 2020/06/11 - rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606 - false sufficient binding region:?-? - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0088"(primer specific pcr)