#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y2Q0 uniprotkb:Q9NV96 intact:EBI-9539324|uniprotkb:Q32M35|uniprotkb:Q32M36|uniprotkb:Q4W5J7|uniprotkb:Q4W5P2|ensembl:ENSP00000371084 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 psi-mi:at8a1_human(display_long)|uniprotkb:ATP8A1(gene name)|psi-mi:ATP8A1(display_short)|uniprotkb:ATPIA(gene name synonym)|uniprotkb:ATPase class I type 8A member 1(gene name synonym)|uniprotkb:Chromaffin granule ATPase II(gene name synonym)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8A1(gene name synonym) psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takatsu et al. (2011) imex:IM-27898|pubmed:21914794 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25507980|imex:IM-27898-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098999.1|refseq:NP_006086.1|refseq:XP_016863134.1|ensembl:ENSG00000124406(gene)|ensembl:ENST00000381668(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7L|rcsb pdb:6K7M|rcsb pdb:6K7N|reactome:R-HSA-6798695|reactome:R-HSA-936837|go:"GO:0005783"(endoplasmic reticulum) refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L - - - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/04/09 2020/04/10 rogid:dgEEryBicD80N5Kh567D+KQDV5g9606 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 rigid:zMEkJn/3TvvyLf2+SHBevulmzXg false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P98196 uniprotkb:Q9NV96 intact:EBI-21519640|uniprotkb:Q5VXT2|ensembl:ENSP00000364796|ensembl:ENSP00000420387 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 psi-mi:at11a_human(display_long)|uniprotkb:ATP11A(gene name)|psi-mi:ATP11A(display_short)|uniprotkb:ATPIH(gene name synonym)|uniprotkb:ATPIS(gene name synonym)|uniprotkb:KIAA1021(gene name synonym)|uniprotkb:ATPase IS(gene name synonym)|uniprotkb:ATPase class VI type 11A(gene name synonym)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP11A(gene name synonym) psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takatsu et al. (2011) imex:IM-27898|pubmed:21914794 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25508011|imex:IM-27898-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056020.2|refseq:NP_115565.3|refseq:XP_005268362.1|refseq:XP_005268363.1|refseq:XP_016875981.1|ensembl:ENSG00000068650(gene)|ensembl:ENST00000375645(transcript)|ensembl:ENST00000487903(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030361|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-6798695|reactome:R-HSA-936837 refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L - - - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/04/09 2020/04/10 rogid:e5SuK2bYtOFzWKRV9VztFObb0209606 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 rigid:4+KLs/ov44NDhogTKdX/rm7AVF8 false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y2G3 uniprotkb:Q9NV96 intact:EBI-20857228|ensembl:ENSP00000321195|uniprotkb:Q96FN1|uniprotkb:Q9UKK7 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 psi-mi:at11b_human(display_long)|uniprotkb:ATPase IR(gene name synonym)|uniprotkb:ATPase class VI type 11B(gene name synonym)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP11B(gene name synonym)|uniprotkb:ATP11B(gene name)|psi-mi:ATP11B(display_short)|uniprotkb:ATPIF(gene name synonym)|uniprotkb:ATPIR(gene name synonym)|uniprotkb:KIAA0956(gene name synonym) psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takatsu et al. (2011) imex:IM-27898|pubmed:21914794 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25508129|imex:IM-27898-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000058063(gene)|ensembl:ENST00000323116(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030362|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-6798695|reactome:R-HSA-936837|refseq:NP_055431.1 refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L - - - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/04/09 2020/04/10 rogid:l+hcko6O7O70ww9vACyqD/6MYTU9606 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 rigid:ClRZMeDPRqVJAj9n4RQiNqQPEvo false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NB49 uniprotkb:Q9NV96 intact:EBI-11279131|uniprotkb:Q5JT69|uniprotkb:Q5JT70|uniprotkb:Q5JT71|uniprotkb:Q5JT72|uniprotkb:Q5JT73|uniprotkb:Q6ZND5|uniprotkb:Q6ZU50|uniprotkb:Q6ZUP7|uniprotkb:Q70IJ9|uniprotkb:Q70IK0|uniprotkb:Q8WX24|ensembl:ENSP00000332756 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 psi-mi:at11c_human(display_long)|uniprotkb:ATP11C(gene name)|psi-mi:ATP11C(display_short)|uniprotkb:ATPIG(gene name synonym)|uniprotkb:ATPIQ(gene name synonym)|uniprotkb:ATPase IQ(gene name synonym)|uniprotkb:ATPase class VI type 11C(gene name synonym)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP11C(gene name synonym) psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takatsu et al. (2011) imex:IM-27898|pubmed:21914794 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25508137|imex:IM-27898-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001010986.1|refseq:NP_775965.2|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030363|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-936837|ensembl:ENSG00000101974(gene)|ensembl:ENST00000327569(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane) refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L - - - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/04/09 2020/04/10 rogid:U7oKi+71kYBQFF3+M1CePoEnXx09606 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 rigid:C+m6X6iVKDl98t6ryaCSxl50nMs false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O43520 uniprotkb:Q3MIR4 intact:EBI-9524729|uniprotkb:Q9BTP8|intact:EBI-28976955|ensembl:ENSP00000497896 intact:EBI-9527107|uniprotkb:B3KR84|uniprotkb:Q14D00|ensembl:ENSP00000450842 psi-mi:at8b1_human(display_long)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B1(gene name synonym)|uniprotkb:ATP8B1(gene name)|psi-mi:ATP8B1(display_short)|uniprotkb:ATPIC(gene name synonym)|uniprotkb:FIC1(gene name synonym)|uniprotkb:PFIC(gene name synonym)|uniprotkb:ATPase class I type 8B member 1(gene name synonym)|uniprotkb:Familial intrahepatic cholestasis type 1(gene name synonym) psi-mi:cc50b_human(display_long)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30B(gene name synonym)|uniprotkb:TMEM30B(gene name)|psi-mi:TMEM30B(display_short)|uniprotkb:CDC50B(gene name synonym)|uniprotkb:Transmembrane protein 30B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takatsu et al. (2011) imex:IM-27898|pubmed:21914794 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25508151|imex:IM-27898-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000497896|refseq:XP_011524324.1|refseq:XP_006722544.1|refseq:NP_005594.1|ensembl:ENSG00000081923(gene)|ensembl:ENST00000648908(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0031526"(brush border membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0045176"(apical protein localization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1903729"(regulation of plasma membrane organization)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|go:"GO:2001225"(regulation of chloride transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR030346|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-936837 refseq:NP_001017970.1|ensembl:ENSG00000182107(gene)|ensembl:ENST00000555868(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030352 - - - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/04/09 2020/04/10 rogid:etMCmFj6oGhBGan/RrxU5eUdWCM9606 rogid:SEW0dE9gp2d2piEq/37EFUxcNOI9606 rigid:GTGeuI97aNQ1cwMsV2WSwS8/TiU false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NV96 uniprotkb:O43520 intact:EBI-2836942|uniprotkb:A8K9V8|uniprotkb:Q96H09|uniprotkb:Q9NSL9|uniprotkb:Q658Z3|uniprotkb:E1P539|ensembl:ENSP00000230461 intact:EBI-9524729|uniprotkb:Q9BTP8|intact:EBI-28976955|ensembl:ENSP00000497896 psi-mi:cc50a_human(display_long)|uniprotkb:TMEM30A(gene name)|psi-mi:TMEM30A(display_short)|uniprotkb:C6orf67(gene name synonym)|uniprotkb:CDC50A(gene name synonym)|uniprotkb:Transmembrane protein 30A(gene name synonym)|uniprotkb:P4-ATPase flippase complex beta subunit TMEM30A(gene name synonym) psi-mi:at8b1_human(display_long)|uniprotkb:P4-ATPase flippase complex alpha subunit ATP8B1(gene name synonym)|uniprotkb:ATP8B1(gene name)|psi-mi:ATP8B1(display_short)|uniprotkb:ATPIC(gene name synonym)|uniprotkb:FIC1(gene name synonym)|uniprotkb:PFIC(gene name synonym)|uniprotkb:ATPase class I type 8B member 1(gene name synonym)|uniprotkb:Familial intrahepatic cholestasis type 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takatsu et al. (2011) imex:IM-27898|pubmed:21914794 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25508158|imex:IM-27898-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001137430.1|refseq:NP_060717.1|ensembl:ENSG00000112697(gene)|ensembl:ENST00000230461(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0061092"(positive regulation of phospholipid translocation)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|interpro:IPR030351|mint:Q9NV96|rcsb pdb:6K7G|rcsb pdb:6K7H|rcsb pdb:6K7I|rcsb pdb:6K7J|rcsb pdb:6K7K|rcsb pdb:6K7M|rcsb pdb:6K7N|rcsb pdb:6LKN|rcsb pdb:7BSP|rcsb pdb:7BSQ|rcsb pdb:7BSS|rcsb pdb:7BSU|rcsb pdb:7BSV|rcsb pdb:7BSW|reactome:R-HSA-6798695|rcsb pdb:6K7L ensembl:ENSP00000497896|refseq:XP_011524324.1|refseq:XP_006722544.1|refseq:NP_005594.1|ensembl:ENSG00000081923(gene)|ensembl:ENST00000648908(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006855"(xenobiotic transmembrane transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0031526"(brush border membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0045176"(apical protein localization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1903729"(regulation of plasma membrane organization)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|go:"GO:2001225"(regulation of chloride transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR030346|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-936837 - - - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/04/09 2020/04/10 rogid:HTSM+3ihZsx2qIRiNhutEb/Kyu09606 rogid:etMCmFj6oGhBGan/RrxU5eUdWCM9606 rigid:2yvSqj7gC2sM/lIgVP3rtz0JSjg false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)