#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P15047 uniprotkb:P15047 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:"MI:0028"(cosedimentation in solution) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25570033|imex:IM-28082-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N - - - figure legend:Fig.1 Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rigid:kpNgUt5/xeN+2Ca0eQxeShzhs40 false his tag:n-n his tag:n-n 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15047 uniprotkb:P15047 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:"MI:0028"(cosedimentation in solution) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25570038|imex:IM-28082-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N - - - figure legend:Fig.1 Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rigid:kpNgUt5/xeN+2Ca0eQxeShzhs40 false his tag:n-n his tag:n-n 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15047 uniprotkb:P15047 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:"MI:0038"(dynamic light scattering) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25570058|imex:IM-28082-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rigid:kpNgUt5/xeN+2Ca0eQxeShzhs40 false his tag:n-n his tag:n-n 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15047 uniprotkb:P15047 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:"MI:0038"(dynamic light scattering) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25570053|imex:IM-28082-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rigid:kpNgUt5/xeN+2Ca0eQxeShzhs40 false his tag:n-n his tag:n-n 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10378 uniprotkb:P15047 intact:EBI-550322|uniprotkb:P15049|uniprotkb:P77773|uniprotkb:Q2MBK7|ensemblbacteria:AAC73695|ensemblbacteria:BAE76349 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 psi-mi:ente_ecoli(display_long)|uniprotkb:entE(gene name)|psi-mi:entE(display_short)|uniprotkb:Enterochelin synthase E(gene name synonym)|uniprotkb:2,3-dihydroxybenzoate-AMP synthase(gene name synonym)|uniprotkb:Dihydroxybenzoic acid-activating enzyme(gene name synonym)|uniprotkb:S-dihydroxybenzoyltransferase(gene name synonym)|uniprotkb:JW0586(locus name)|uniprotkb:b0594(locus name)|uniprotkb:2,3-dihydroxybenzoate-AMP ligase(gene name synonym) psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:"MI:0096"(pull down) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25570071|imex:IM-28082-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415126.1|refseq:WP_000026812.1|dip:DIP-9515N|ensemblbacteria:AAC73695(transcript)|ensemblbacteria:b0594(gene)|ensemblbacteria:BAE76349(gene)|ensemblbacteria:BAE76349(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008668"("(2,3-dihydroxybenzoyl)adenylate synthase activity")|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0047527"(2,3-dihydroxybenzoate-serine ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011963(2,3-dihydroxybenzoate-AMP ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|rcsb pdb:3RG2|rcsb pdb:4IZ6|rcsb pdb:6IYK|rcsb pdb:6IYL refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N - - - figure legend:Fig.2A, Supp. Table 1|comment:"Interaction observed in the presence or absence of 2,3-dihydroxybenzoate (DHB)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 rogid:U8WqstlK8t7Q0ERuM13rkw1//yw83333 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rigid:JKKW9skdzCZDoIfQZKI49EItN1Q false - his tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15047 uniprotkb:P10378 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 intact:EBI-550322|uniprotkb:P15049|uniprotkb:P77773|uniprotkb:Q2MBK7|ensemblbacteria:AAC73695|ensemblbacteria:BAE76349 psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:ente_ecoli(display_long)|uniprotkb:entE(gene name)|psi-mi:entE(display_short)|uniprotkb:Enterochelin synthase E(gene name synonym)|uniprotkb:2,3-dihydroxybenzoate-AMP synthase(gene name synonym)|uniprotkb:Dihydroxybenzoic acid-activating enzyme(gene name synonym)|uniprotkb:S-dihydroxybenzoyltransferase(gene name synonym)|uniprotkb:JW0586(locus name)|uniprotkb:b0594(locus name)|uniprotkb:2,3-dihydroxybenzoate-AMP ligase(gene name synonym) psi-mi:"MI:0096"(pull down) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25570082|imex:IM-28082-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N refseq:NP_415126.1|refseq:WP_000026812.1|dip:DIP-9515N|ensemblbacteria:AAC73695(transcript)|ensemblbacteria:b0594(gene)|ensemblbacteria:BAE76349(gene)|ensemblbacteria:BAE76349(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008668"("(2,3-dihydroxybenzoyl)adenylate synthase activity")|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0047527"(2,3-dihydroxybenzoate-serine ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011963(2,3-dihydroxybenzoate-AMP ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|rcsb pdb:3RG2|rcsb pdb:4IZ6|rcsb pdb:6IYK|rcsb pdb:6IYL - - - figure legend:Fig.2B, Supp. Table 1|comment:"Interaction observed in the absence or absence of 2,3-dihydroxybenzoate (DHB)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rogid:U8WqstlK8t7Q0ERuM13rkw1//yw83333 rigid:JKKW9skdzCZDoIfQZKI49EItN1Q false - his tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P10378 uniprotkb:P0ADI4 intact:EBI-550322|uniprotkb:P15049|uniprotkb:P77773|uniprotkb:Q2MBK7|ensemblbacteria:AAC73695|ensemblbacteria:BAE76349 intact:EBI-547993|uniprotkb:P15048|uniprotkb:Q2MBK6|ensemblbacteria:AAC73696|ensemblbacteria:BAE76350 psi-mi:ente_ecoli(display_long)|uniprotkb:entE(gene name)|psi-mi:entE(display_short)|uniprotkb:Enterochelin synthase E(gene name synonym)|uniprotkb:2,3-dihydroxybenzoate-AMP synthase(gene name synonym)|uniprotkb:Dihydroxybenzoic acid-activating enzyme(gene name synonym)|uniprotkb:S-dihydroxybenzoyltransferase(gene name synonym)|uniprotkb:JW0586(locus name)|uniprotkb:b0594(locus name)|uniprotkb:2,3-dihydroxybenzoate-AMP ligase(gene name synonym) psi-mi:entb_ecoli(display_long)|uniprotkb:entB(gene name)|psi-mi:entB(display_short)|uniprotkb:entG(gene name synonym)|uniprotkb:b0595(locus name)|uniprotkb:Enterochelin synthase B(gene name synonym)|uniprotkb:JW0587(locus name)|uniprotkb:Enterobactin biosynthesis bifunctional protein EntB(gene name synonym) psi-mi:"MI:0096"(pull down) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25570089|imex:IM-28082-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415126.1|refseq:WP_000026812.1|dip:DIP-9515N|ensemblbacteria:AAC73695(transcript)|ensemblbacteria:b0594(gene)|ensemblbacteria:BAE76349(gene)|ensemblbacteria:BAE76349(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008668"("(2,3-dihydroxybenzoyl)adenylate synthase activity")|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0047527"(2,3-dihydroxybenzoate-serine ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011963(2,3-dihydroxybenzoate-AMP ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|rcsb pdb:3RG2|rcsb pdb:4IZ6|rcsb pdb:6IYK|rcsb pdb:6IYL refseq:NP_415127.1|refseq:WP_001007138.1|dip:DIP-9512N|ensemblbacteria:AAC73696(transcript)|ensemblbacteria:b0595(gene)|ensemblbacteria:BAE76350(gene)|ensemblbacteria:BAE76350(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008908"(isochorismatase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0016765"("transferase activity, transferring alkyl or aryl (other than methyl) groups")|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0047527"(2,3-dihydroxybenzoate-serine ligase activity)|interpro:IPR000868(Isochorismatase hydrolase)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR016291(Isochorismatase, bacteria)|interpro:IPR036380|interpro:IPR036736|rcsb pdb:2FQ1|rcsb pdb:3RG2|rcsb pdb:4IZ6 - - - figure legend:Fig.2B, Supp. Table 1|comment:"Interaction observed in the presence of 2,3-dihydroxybenzoate (DHB)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 rogid:U8WqstlK8t7Q0ERuM13rkw1//yw83333 rogid:aki1JalV1cYVwtGKVqmvJJfcu7M83333 rigid:1Np3ZVvQuVIatNqIC5hvS3Z560o false his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P10378 uniprotkb:P15047 intact:EBI-550322|uniprotkb:P15049|uniprotkb:P77773|uniprotkb:Q2MBK7|ensemblbacteria:AAC73695|ensemblbacteria:BAE76349 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 psi-mi:ente_ecoli(display_long)|uniprotkb:entE(gene name)|psi-mi:entE(display_short)|uniprotkb:Enterochelin synthase E(gene name synonym)|uniprotkb:2,3-dihydroxybenzoate-AMP synthase(gene name synonym)|uniprotkb:Dihydroxybenzoic acid-activating enzyme(gene name synonym)|uniprotkb:S-dihydroxybenzoyltransferase(gene name synonym)|uniprotkb:JW0586(locus name)|uniprotkb:b0594(locus name)|uniprotkb:2,3-dihydroxybenzoate-AMP ligase(gene name synonym) psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:"MI:0096"(pull down) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25570089|imex:IM-28082-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415126.1|refseq:WP_000026812.1|dip:DIP-9515N|ensemblbacteria:AAC73695(transcript)|ensemblbacteria:b0594(gene)|ensemblbacteria:BAE76349(gene)|ensemblbacteria:BAE76349(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008668"("(2,3-dihydroxybenzoyl)adenylate synthase activity")|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0047527"(2,3-dihydroxybenzoate-serine ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011963(2,3-dihydroxybenzoate-AMP ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|rcsb pdb:3RG2|rcsb pdb:4IZ6|rcsb pdb:6IYK|rcsb pdb:6IYL refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N - - - figure legend:Fig.2B, Supp. Table 1|comment:"Interaction observed in the presence of 2,3-dihydroxybenzoate (DHB)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 rogid:U8WqstlK8t7Q0ERuM13rkw1//yw83333 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rigid:1Np3ZVvQuVIatNqIC5hvS3Z560o false his tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15047 uniprotkb:P10378 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 intact:EBI-550322|uniprotkb:P15049|uniprotkb:P77773|uniprotkb:Q2MBK7|ensemblbacteria:AAC73695|ensemblbacteria:BAE76349 psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:ente_ecoli(display_long)|uniprotkb:entE(gene name)|psi-mi:entE(display_short)|uniprotkb:Enterochelin synthase E(gene name synonym)|uniprotkb:2,3-dihydroxybenzoate-AMP synthase(gene name synonym)|uniprotkb:Dihydroxybenzoic acid-activating enzyme(gene name synonym)|uniprotkb:S-dihydroxybenzoyltransferase(gene name synonym)|uniprotkb:JW0586(locus name)|uniprotkb:b0594(locus name)|uniprotkb:2,3-dihydroxybenzoate-AMP ligase(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25570157|imex:IM-28082-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N refseq:NP_415126.1|refseq:WP_000026812.1|dip:DIP-9515N|ensemblbacteria:AAC73695(transcript)|ensemblbacteria:b0594(gene)|ensemblbacteria:BAE76349(gene)|ensemblbacteria:BAE76349(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008668"("(2,3-dihydroxybenzoyl)adenylate synthase activity")|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0047527"(2,3-dihydroxybenzoate-serine ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011963(2,3-dihydroxybenzoate-AMP ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|rcsb pdb:3RG2|rcsb pdb:4IZ6|rcsb pdb:6IYK|rcsb pdb:6IYL - - - figure legend:Supp. Table 2, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rogid:U8WqstlK8t7Q0ERuM13rkw1//yw83333 rigid:JKKW9skdzCZDoIfQZKI49EItN1Q false his tag:n-n his tag:n-n 4 4 psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) chebi:"CHEBI:18026" uniprotkb:P10378 intact:EBI-13638726|chebi:"CHEBI:41901"|chebi:"CHEBI:885"|chebi:"CHEBI:19320" intact:EBI-550322|uniprotkb:P15049|uniprotkb:P77773|uniprotkb:Q2MBK7|ensemblbacteria:AAC73695|ensemblbacteria:BAE76349 psi-mi:2,3-dihydroxybenzoic acid(display_short)|psi-mi:"CHEBI:18026"(display_long)|intact:2,3 DHB(synonym)|intact:2,3-DIHYDROXY-BENZOIC ACID(synonym)|intact:2,3-dihydroxybenzoic acid(synonym)|intact:2,3-Dihydroxybenzoic acid(synonym)|intact:2-pyrocatechuic acid(synonym)|intact:3-hydroxysalicylic acid(synonym)|intact:catechol-3-carboxylic acid(synonym)|intact:DOBK(synonym)|intact:o-pyrocatechuic acid(synonym)|intact:pyrocatechuic acid(synonym)|intact:2,3-dihydroxybenzoic acid(iupac name) psi-mi:ente_ecoli(display_long)|uniprotkb:entE(gene name)|psi-mi:entE(display_short)|uniprotkb:Enterochelin synthase E(gene name synonym)|uniprotkb:2,3-dihydroxybenzoate-AMP synthase(gene name synonym)|uniprotkb:Dihydroxybenzoic acid-activating enzyme(gene name synonym)|uniprotkb:S-dihydroxybenzoyltransferase(gene name synonym)|uniprotkb:JW0586(locus name)|uniprotkb:b0594(locus name)|uniprotkb:2,3-dihydroxybenzoate-AMP ligase(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25570128|imex:IM-28082-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415126.1|refseq:WP_000026812.1|dip:DIP-9515N|ensemblbacteria:AAC73695(transcript)|ensemblbacteria:b0594(gene)|ensemblbacteria:BAE76349(gene)|ensemblbacteria:BAE76349(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008668"("(2,3-dihydroxybenzoyl)adenylate synthase activity")|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0047527"(2,3-dihydroxybenzoate-serine ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011963(2,3-dihydroxybenzoate-AMP ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|rcsb pdb:3RG2|rcsb pdb:4IZ6|rcsb pdb:6IYK|rcsb pdb:6IYL - - - figure legend:Fig.4,6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 - rogid:U8WqstlK8t7Q0ERuM13rkw1//yw83333 - false - his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18026" uniprotkb:P15047 intact:EBI-13638726|chebi:"CHEBI:41901"|chebi:"CHEBI:885"|chebi:"CHEBI:19320" intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 psi-mi:2,3-dihydroxybenzoic acid(display_short)|psi-mi:"CHEBI:18026"(display_long)|intact:2,3 DHB(synonym)|intact:2,3-DIHYDROXY-BENZOIC ACID(synonym)|intact:2,3-dihydroxybenzoic acid(synonym)|intact:2,3-Dihydroxybenzoic acid(synonym)|intact:2-pyrocatechuic acid(synonym)|intact:3-hydroxysalicylic acid(synonym)|intact:catechol-3-carboxylic acid(synonym)|intact:DOBK(synonym)|intact:o-pyrocatechuic acid(synonym)|intact:pyrocatechuic acid(synonym)|intact:2,3-dihydroxybenzoic acid(iupac name) psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25570134|imex:IM-28082-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N - - - figure legend:Figs.4, 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/10/12 - rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 - false - his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18026" uniprotkb:P10378 intact:EBI-13638726|chebi:"CHEBI:41901"|chebi:"CHEBI:885"|chebi:"CHEBI:19320" intact:EBI-550322|uniprotkb:P15049|uniprotkb:P77773|uniprotkb:Q2MBK7|ensemblbacteria:AAC73695|ensemblbacteria:BAE76349 psi-mi:2,3-dihydroxybenzoic acid(display_short)|psi-mi:"CHEBI:18026"(display_long)|intact:2,3 DHB(synonym)|intact:2,3-DIHYDROXY-BENZOIC ACID(synonym)|intact:2,3-dihydroxybenzoic acid(synonym)|intact:2,3-Dihydroxybenzoic acid(synonym)|intact:2-pyrocatechuic acid(synonym)|intact:3-hydroxysalicylic acid(synonym)|intact:catechol-3-carboxylic acid(synonym)|intact:DOBK(synonym)|intact:o-pyrocatechuic acid(synonym)|intact:pyrocatechuic acid(synonym)|intact:2,3-dihydroxybenzoic acid(iupac name) psi-mi:ente_ecoli(display_long)|uniprotkb:entE(gene name)|psi-mi:entE(display_short)|uniprotkb:Enterochelin synthase E(gene name synonym)|uniprotkb:2,3-dihydroxybenzoate-AMP synthase(gene name synonym)|uniprotkb:Dihydroxybenzoic acid-activating enzyme(gene name synonym)|uniprotkb:S-dihydroxybenzoyltransferase(gene name synonym)|uniprotkb:JW0586(locus name)|uniprotkb:b0594(locus name)|uniprotkb:2,3-dihydroxybenzoate-AMP ligase(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25570134|imex:IM-28082-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415126.1|refseq:WP_000026812.1|dip:DIP-9515N|ensemblbacteria:AAC73695(transcript)|ensemblbacteria:b0594(gene)|ensemblbacteria:BAE76349(gene)|ensemblbacteria:BAE76349(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008668"("(2,3-dihydroxybenzoyl)adenylate synthase activity")|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0047527"(2,3-dihydroxybenzoate-serine ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011963(2,3-dihydroxybenzoate-AMP ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|rcsb pdb:3RG2|rcsb pdb:4IZ6|rcsb pdb:6IYK|rcsb pdb:6IYL - - - figure legend:Figs.4, 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/10/12 - rogid:U8WqstlK8t7Q0ERuM13rkw1//yw83333 - false - his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18026" uniprotkb:P10378 intact:EBI-13638726|chebi:"CHEBI:41901"|chebi:"CHEBI:885"|chebi:"CHEBI:19320" intact:EBI-550322|uniprotkb:P15049|uniprotkb:P77773|uniprotkb:Q2MBK7|ensemblbacteria:AAC73695|ensemblbacteria:BAE76349 psi-mi:2,3-dihydroxybenzoic acid(display_short)|psi-mi:"CHEBI:18026"(display_long)|intact:2,3 DHB(synonym)|intact:2,3-DIHYDROXY-BENZOIC ACID(synonym)|intact:2,3-dihydroxybenzoic acid(synonym)|intact:2,3-Dihydroxybenzoic acid(synonym)|intact:2-pyrocatechuic acid(synonym)|intact:3-hydroxysalicylic acid(synonym)|intact:catechol-3-carboxylic acid(synonym)|intact:DOBK(synonym)|intact:o-pyrocatechuic acid(synonym)|intact:pyrocatechuic acid(synonym)|intact:2,3-dihydroxybenzoic acid(iupac name) psi-mi:ente_ecoli(display_long)|uniprotkb:entE(gene name)|psi-mi:entE(display_short)|uniprotkb:Enterochelin synthase E(gene name synonym)|uniprotkb:2,3-dihydroxybenzoate-AMP synthase(gene name synonym)|uniprotkb:Dihydroxybenzoic acid-activating enzyme(gene name synonym)|uniprotkb:S-dihydroxybenzoyltransferase(gene name synonym)|uniprotkb:JW0586(locus name)|uniprotkb:b0594(locus name)|uniprotkb:2,3-dihydroxybenzoate-AMP ligase(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25570150|imex:IM-28082-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_415126.1|refseq:WP_000026812.1|dip:DIP-9515N|ensemblbacteria:AAC73695(transcript)|ensemblbacteria:b0594(gene)|ensemblbacteria:BAE76349(gene)|ensemblbacteria:BAE76349(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008668"("(2,3-dihydroxybenzoyl)adenylate synthase activity")|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0047527"(2,3-dihydroxybenzoate-serine ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011963(2,3-dihydroxybenzoate-AMP ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|rcsb pdb:3RG2|rcsb pdb:4IZ6|rcsb pdb:6IYK|rcsb pdb:6IYL - - - figure legend:Fig.5|comment:No additional increase in anisotropy was observed with the addition of entA|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 - rogid:U8WqstlK8t7Q0ERuM13rkw1//yw83333 - false - his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15047 uniprotkb:P10378 intact:EBI-1118936|uniprotkb:P77100|uniprotkb:Q2MBK5|ensemblbacteria:AAC73697|ensemblbacteria:BAE76351 intact:EBI-550322|uniprotkb:P15049|uniprotkb:P77773|uniprotkb:Q2MBK7|ensemblbacteria:AAC73695|ensemblbacteria:BAE76349 psi-mi:enta_ecoli(display_long)|uniprotkb:entA(gene name)|psi-mi:entA(display_short)|uniprotkb:Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase(gene name synonym)|uniprotkb:JW0588(locus name)|uniprotkb:b0596(locus name) psi-mi:ente_ecoli(display_long)|uniprotkb:entE(gene name)|psi-mi:entE(display_short)|uniprotkb:Enterochelin synthase E(gene name synonym)|uniprotkb:2,3-dihydroxybenzoate-AMP synthase(gene name synonym)|uniprotkb:Dihydroxybenzoic acid-activating enzyme(gene name synonym)|uniprotkb:S-dihydroxybenzoyltransferase(gene name synonym)|uniprotkb:JW0586(locus name)|uniprotkb:b0594(locus name)|uniprotkb:2,3-dihydroxybenzoate-AMP ligase(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Khalil et al. (2011) pubmed:21166461|imex:IM-28082 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25570110|imex:IM-28082-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415128.1|ensemblbacteria:AAC73697(transcript)|ensemblbacteria:b0596(gene)|ensemblbacteria:BAE76351(gene)|ensemblbacteria:BAE76351(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008667"(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity)|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003560(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase)|interpro:IPR020904|interpro:IPR036291|rcsb pdb:2FWM|refseq:WP_000347651.1|dip:DIP-9511N refseq:NP_415126.1|refseq:WP_000026812.1|dip:DIP-9515N|ensemblbacteria:AAC73695(transcript)|ensemblbacteria:b0594(gene)|ensemblbacteria:BAE76349(gene)|ensemblbacteria:BAE76349(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008668"("(2,3-dihydroxybenzoyl)adenylate synthase activity")|go:"GO:0009239"(enterobactin biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0047527"(2,3-dihydroxybenzoate-serine ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011963(2,3-dihydroxybenzoate-AMP ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|rcsb pdb:3RG2|rcsb pdb:4IZ6|rcsb pdb:6IYK|rcsb pdb:6IYL - - - figure legend:Fig.7, Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/23 2020/04/23 rogid:xOemoPizq7i1Dfn1CiSE9dnEPww83333 rogid:U8WqstlK8t7Q0ERuM13rkw1//yw83333 rigid:JKKW9skdzCZDoIfQZKI49EItN1Q false his tag:n-n his tag:n-n 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)