#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32455	uniprotkb:P32455	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26453932|imex:IM-28522-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:6B0DBE/CvuH+H1gqYfA6RT1Kqrs	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32455	uniprotkb:P32455	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26453955|imex:IM-28522-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Supp Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:6B0DBE/CvuH+H1gqYfA6RT1Kqrs	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32456	uniprotkb:P32456	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26453963|imex:IM-28522-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	-	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:DhRJPTlMOqewZWwepR+fTPKZ3VA	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32456	uniprotkb:P32456	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26453971|imex:IM-28522-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	-	-	-	figure legend:Supp Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:DhRJPTlMOqewZWwepR+fTPKZ3VA	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96PP8	uniprotkb:Q96PP8	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26453980|imex:IM-28522-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	-	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:QPEi1jcghoYpHMrlZd14ekA7jBA	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96PP8	uniprotkb:Q96PP8	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26453988|imex:IM-28522-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	-	-	-	figure legend:Supp Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:QPEi1jcghoYpHMrlZd14ekA7jBA	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32456	uniprotkb:P32455	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454105|imex:IM-28522-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:k0zZqKzzMiFR/SSXhRyVfDdS/80	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96PP8	uniprotkb:P32455	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454113|imex:IM-28522-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:YTC+Xpzsm8lVZcs+7uAg684iQL0	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32455	uniprotkb:P32456	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454121|imex:IM-28522-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	-	-	-	figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:k0zZqKzzMiFR/SSXhRyVfDdS/80	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96PP8	uniprotkb:P32456	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454129|imex:IM-28522-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	-	-	-	figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:odwW+Mpg0h/xtdQvJqObd0Bgdfk	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32455	uniprotkb:Q96PP8	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454138|imex:IM-28522-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	-	-	-	figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:YTC+Xpzsm8lVZcs+7uAg684iQL0	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32456	uniprotkb:Q96PP8	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454146|imex:IM-28522-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	-	-	-	figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:odwW+Mpg0h/xtdQvJqObd0Bgdfk	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32455	uniprotkb:P32456	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454154|imex:IM-28522-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	-	-	-	figure legend:Supp Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:k0zZqKzzMiFR/SSXhRyVfDdS/80	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32455	uniprotkb:Q96PP8	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454162|imex:IM-28522-85	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	-	-	-	figure legend:Supp Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:YTC+Xpzsm8lVZcs+7uAg684iQL0	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32456	uniprotkb:P32455	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454180|imex:IM-28522-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Supp Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:k0zZqKzzMiFR/SSXhRyVfDdS/80	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32456	uniprotkb:Q96PP8	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454188|imex:IM-28522-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	-	-	-	figure legend:Supp Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:odwW+Mpg0h/xtdQvJqObd0Bgdfk	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96PP8	uniprotkb:P32455	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454196|imex:IM-28522-89	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Supp Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:YTC+Xpzsm8lVZcs+7uAg684iQL0	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96PP8	uniprotkb:P32456	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454204|imex:IM-28522-91	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	-	-	-	figure legend:Supp Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:odwW+Mpg0h/xtdQvJqObd0Bgdfk	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H0R5	uniprotkb:P32455	intact:EBI-2798916|uniprotkb:A2A317|uniprotkb:B2RTW0|uniprotkb:Q05D54|uniprotkb:Q9NV33|uniprotkb:A6NF86|uniprotkb:Q5T8L9|uniprotkb:Q5T8L8|uniprotkb:Q6P3V3|uniprotkb:F8UW81|ensembl:ENSP00000359512	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp3_human(display_long)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GBP3(gene name)|psi-mi:GBP3(display_short)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472546|imex:IM-28522-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306110.1|refseq:NP_060754.2|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q9H0R5|reactome:R-HSA-877300|ensembl:ENSG00000117226(gene)|ensembl:ENST00000370481(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Supp Fig. 9A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:DZ/4GjzK0RWder8XbSKaDpHUCYs9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:yfftF4Z5y1ThWAfNt6B2yy18PCo	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96PP9	uniprotkb:P32455	intact:EBI-20840650|ensembl:ENSP00000359490|uniprotkb:B2R630|uniprotkb:Q05D63|uniprotkb:Q6NSL0|uniprotkb:Q86T99	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp4_human(display_long)|uniprotkb:GTP-binding protein 4(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 4(gene name synonym)|uniprotkb:GBP4(gene name)|psi-mi:GBP4(display_short)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472554|imex:IM-28522-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162654(gene)|ensembl:ENST00000355754(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|reactome:R-HSA-877300|refseq:NP_443173.2	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Supp Fig. 9A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:pFjhPH/83j+kU9zCy8cxRQ/lTTA9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:GdRsmNBA3OR0hO1EPB/+zG9HTtM	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96PP9	uniprotkb:P32456	intact:EBI-20840650|ensembl:ENSP00000359490|uniprotkb:B2R630|uniprotkb:Q05D63|uniprotkb:Q6NSL0|uniprotkb:Q86T99	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp4_human(display_long)|uniprotkb:GTP-binding protein 4(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 4(gene name synonym)|uniprotkb:GBP4(gene name)|psi-mi:GBP4(display_short)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472562|imex:IM-28522-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162654(gene)|ensembl:ENST00000355754(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|reactome:R-HSA-877300|refseq:NP_443173.2	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	-	-	-	figure legend:Supp Fig. 9A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:pFjhPH/83j+kU9zCy8cxRQ/lTTA9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:2B5RuFb/4rnyII67yHH33YmOfyM	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H0R5	uniprotkb:P32456	intact:EBI-2798916|uniprotkb:A2A317|uniprotkb:B2RTW0|uniprotkb:Q05D54|uniprotkb:Q9NV33|uniprotkb:A6NF86|uniprotkb:Q5T8L9|uniprotkb:Q5T8L8|uniprotkb:Q6P3V3|uniprotkb:F8UW81|ensembl:ENSP00000359512	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp3_human(display_long)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GBP3(gene name)|psi-mi:GBP3(display_short)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472570|imex:IM-28522-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306110.1|refseq:NP_060754.2|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q9H0R5|reactome:R-HSA-877300|ensembl:ENSG00000117226(gene)|ensembl:ENST00000370481(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	-	-	-	figure legend:Supp Fig. 9A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:DZ/4GjzK0RWder8XbSKaDpHUCYs9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:CyACL6qFaWnjePhzvLQCFQ210o4	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H0R5	uniprotkb:Q9H0R5	intact:EBI-2798916|uniprotkb:A2A317|uniprotkb:B2RTW0|uniprotkb:Q05D54|uniprotkb:Q9NV33|uniprotkb:A6NF86|uniprotkb:Q5T8L9|uniprotkb:Q5T8L8|uniprotkb:Q6P3V3|uniprotkb:F8UW81|ensembl:ENSP00000359512	intact:EBI-2798916|uniprotkb:A2A317|uniprotkb:B2RTW0|uniprotkb:Q05D54|uniprotkb:Q9NV33|uniprotkb:A6NF86|uniprotkb:Q5T8L9|uniprotkb:Q5T8L8|uniprotkb:Q6P3V3|uniprotkb:F8UW81|ensembl:ENSP00000359512	psi-mi:gbp3_human(display_long)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GBP3(gene name)|psi-mi:GBP3(display_short)	psi-mi:gbp3_human(display_long)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GBP3(gene name)|psi-mi:GBP3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472578|imex:IM-28522-77	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306110.1|refseq:NP_060754.2|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q9H0R5|reactome:R-HSA-877300|ensembl:ENSG00000117226(gene)|ensembl:ENST00000370481(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)	refseq:NP_001306110.1|refseq:NP_060754.2|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q9H0R5|reactome:R-HSA-877300|ensembl:ENSG00000117226(gene)|ensembl:ENST00000370481(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)	-	-	-	figure legend:Supp Fig. 9A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:DZ/4GjzK0RWder8XbSKaDpHUCYs9606	rogid:DZ/4GjzK0RWder8XbSKaDpHUCYs9606	rigid:z3T/lZbhW5rcZOegEA0XiG95Gcs	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96PP9	uniprotkb:Q96PP9	intact:EBI-20840650|ensembl:ENSP00000359490|uniprotkb:B2R630|uniprotkb:Q05D63|uniprotkb:Q6NSL0|uniprotkb:Q86T99	intact:EBI-20840650|ensembl:ENSP00000359490|uniprotkb:B2R630|uniprotkb:Q05D63|uniprotkb:Q6NSL0|uniprotkb:Q86T99	psi-mi:gbp4_human(display_long)|uniprotkb:GTP-binding protein 4(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 4(gene name synonym)|uniprotkb:GBP4(gene name)|psi-mi:GBP4(display_short)	psi-mi:gbp4_human(display_long)|uniprotkb:GTP-binding protein 4(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 4(gene name synonym)|uniprotkb:GBP4(gene name)|psi-mi:GBP4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472586|imex:IM-28522-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162654(gene)|ensembl:ENST00000355754(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|reactome:R-HSA-877300|refseq:NP_443173.2	ensembl:ENSG00000162654(gene)|ensembl:ENST00000355754(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|reactome:R-HSA-877300|refseq:NP_443173.2	-	-	-	figure legend:Supp Fig. 9A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:pFjhPH/83j+kU9zCy8cxRQ/lTTA9606	rogid:pFjhPH/83j+kU9zCy8cxRQ/lTTA9606	rigid:JEALETSwChAF6Z6cwR+hE4m9KpE	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H0R5	uniprotkb:Q96PP8	intact:EBI-2798916|uniprotkb:A2A317|uniprotkb:B2RTW0|uniprotkb:Q05D54|uniprotkb:Q9NV33|uniprotkb:A6NF86|uniprotkb:Q5T8L9|uniprotkb:Q5T8L8|uniprotkb:Q6P3V3|uniprotkb:F8UW81|ensembl:ENSP00000359512	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp3_human(display_long)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GBP3(gene name)|psi-mi:GBP3(display_short)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472594|imex:IM-28522-97	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306110.1|refseq:NP_060754.2|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q9H0R5|reactome:R-HSA-877300|ensembl:ENSG00000117226(gene)|ensembl:ENST00000370481(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	-	-	-	figure legend:Supp. figure 9A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:DZ/4GjzK0RWder8XbSKaDpHUCYs9606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:GtN5LkWovAIqx2/wtGeRgavjXBs	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q96PP9	uniprotkb:Q96PP8	intact:EBI-20840650|ensembl:ENSP00000359490|uniprotkb:B2R630|uniprotkb:Q05D63|uniprotkb:Q6NSL0|uniprotkb:Q86T99	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp4_human(display_long)|uniprotkb:GTP-binding protein 4(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 4(gene name synonym)|uniprotkb:GBP4(gene name)|psi-mi:GBP4(display_short)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472602|imex:IM-28522-99	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162654(gene)|ensembl:ENST00000355754(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|reactome:R-HSA-877300|refseq:NP_443173.2	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	-	-	-	figure legend:Supp. figure 9A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:pFjhPH/83j+kU9zCy8cxRQ/lTTA9606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:+2F0Cq0Y1H2lwwwXhHyTTucfRQs	false	vsv tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32455	uniprotkb:P32455	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454041|imex:IM-28522-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:6B0DBE/CvuH+H1gqYfA6RT1Kqrs	false	venus c-terminal fragment:?-?	venus n-terminal fragment:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32456	uniprotkb:P32456	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454049|imex:IM-28522-101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	-	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:DhRJPTlMOqewZWwepR+fTPKZ3VA	false	venus c-terminal fragment:n-n	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96PP8	uniprotkb:Q96PP8	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454057|imex:IM-28522-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	-	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/24	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:QPEi1jcghoYpHMrlZd14ekA7jBA	false	venus c-terminal fragment:n-n	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96PP8	uniprotkb:Q96PP8	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454087|imex:IM-28522-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	go:"GO:0005794"(Golgi apparatus)	-	-	figure legend:Fig. 4C, Supp. Fig. 4B|comment:When cells were treated with a farnesyl transferase  inhibitor or geranylgeranyl transferase type I inhibitor, proteins could could still dimerize.  However the fluorescent signals were evenly distributed throughout the cytoplasm indicating that isoprenylation is necessary for membrane affinity of the dimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:QPEi1jcghoYpHMrlZd14ekA7jBA	false	venus c-terminal fragment:n-n|vsv tag:?-?	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32455	uniprotkb:P32455	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454071|imex:IM-28522-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Supp. Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:6B0DBE/CvuH+H1gqYfA6RT1Kqrs	false	venus c-terminal fragment:n-n|vsv tag:?-?|mutation disrupting interaction strength:51-51	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32456	uniprotkb:P32456	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454079|imex:IM-28522-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	go:"GO:0048471"(perinuclear region of cytoplasm)	-	-	figure legend:Fig. 4C, Supp. Fig. 4 A/B|comment:When cells were treated with a farnesyl transferase  inhibitor or geranylgeranyl transferase type I inhibitor, proteins could could still dimerize.  However the fluorescent signals were evenly distributed throughout the cytoplasm indicating that isoprenylation is necessary for membrane affinity of the dimers.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:DhRJPTlMOqewZWwepR+fTPKZ3VA	false	venus c-terminal fragment:n-n|vsv tag:?-?	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32456	uniprotkb:P32455	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454212|imex:IM-28522-93	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	go:"GO:0031982"(vesicle)	-	-	figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:k0zZqKzzMiFR/SSXhRyVfDdS/80	false	venus c-terminal fragment:n-n|vsv tag:?-?	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32455	uniprotkb:P32456	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454229|imex:IM-28522-95	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	go:"GO:0031982"(vesicle)	-	-	figure legend:Fig. 5B, Supp. 7B|comment:Inhibition of GBP-1 farnesylation with a farnesyl transferase inhibitor  induced  localization  to the perinuclear membranes.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:k0zZqKzzMiFR/SSXhRyVfDdS/80	false	venus c-terminal fragment:n-n|vsv tag:?-?	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96PP8	uniprotkb:P32455	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454240|imex:IM-28522-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	go:"GO:0031982"(vesicle)	-	-	figure legend:Fig. 5B, Supp. Fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:YTC+Xpzsm8lVZcs+7uAg684iQL0	false	venus c-terminal fragment:n-n|vsv tag:?-?	venus n-terminal fragment:n-n|mutation disrupting interaction strength:51-51	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32455	uniprotkb:Q96PP8	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454318|imex:IM-28522-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	go:"GO:0031982"(vesicle)	-	-	figure legend:Fig. 5B, Supp. figure 7B|comment:Inhibition of GBP-1 farnesylation with a farnesyl transferase inhibitor  induced  localization  to the perinuclear membranes.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:YTC+Xpzsm8lVZcs+7uAg684iQL0	false	venus c-terminal fragment:n-n|vsv tag:?-?	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32456	uniprotkb:Q96PP8	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454329|imex:IM-28522-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	go:"GO:0005794"(Golgi apparatus)	-	-	figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:odwW+Mpg0h/xtdQvJqObd0Bgdfk	false	venus c-terminal fragment:n-n|vsv tag:?-?	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32455	uniprotkb:P32455	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454404|imex:IM-28522-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:4C, Supp. Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:6B0DBE/CvuH+H1gqYfA6RT1Kqrs	false	venus c-terminal fragment:n-n|vsv tag:?-?	venus n-terminal fragment:n-n|mutation disrupting interaction strength:51-51	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32456	uniprotkb:P32455	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454418|imex:IM-28522-103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Supp. Fig 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:k0zZqKzzMiFR/SSXhRyVfDdS/80	false	venus c-terminal fragment:n-n|vsv tag:?-?	mutation disrupting interaction strength:51-51|venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96PP8	uniprotkb:P32455	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454431|imex:IM-28522-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	go:"GO:0031982"(vesicle)	-	-	figure legend:Supp. Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:YTC+Xpzsm8lVZcs+7uAg684iQL0	false	venus c-terminal fragment:n-n|vsv tag:?-?	mutation disrupting interaction strength:51-51|venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32455	uniprotkb:P32456	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454444|imex:IM-28522-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	-	-	-	figure legend:Fig. 5B, Supp. fig 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:k0zZqKzzMiFR/SSXhRyVfDdS/80	false	venus c-terminal fragment:n-n|vsv tag:?-?|mutation disrupting interaction strength:51-51	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32455	uniprotkb:Q96PP8	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454459|imex:IM-28522-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	-	-	-	figure legend:Supp. Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:YTC+Xpzsm8lVZcs+7uAg684iQL0	false	venus c-terminal fragment:n-n|vsv tag:?-?|mutation disrupting interaction strength:51-51	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96PP8	uniprotkb:P32456	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454472|imex:IM-28522-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	go:"GO:0005794"(Golgi apparatus)	-	-	figure legend:Fig. 5B, Supp. Fig. 7B|comment:"Treatment with GGTI (geranylgeranyl transferase type I inhibitor) resulted in a diffuse localization pattern for GBP-2/GBP-5 heterodimers ."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/25	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:odwW+Mpg0h/xtdQvJqObd0Bgdfk	false	venus c-terminal fragment:n-n|vsv tag:?-?	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9H0R5	uniprotkb:P32455	intact:EBI-2798916|uniprotkb:A2A317|uniprotkb:B2RTW0|uniprotkb:Q05D54|uniprotkb:Q9NV33|uniprotkb:A6NF86|uniprotkb:Q5T8L9|uniprotkb:Q5T8L8|uniprotkb:Q6P3V3|uniprotkb:F8UW81|ensembl:ENSP00000359512	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp3_human(display_long)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GBP3(gene name)|psi-mi:GBP3(display_short)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472610|imex:IM-28522-105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306110.1|refseq:NP_060754.2|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q9H0R5|reactome:R-HSA-877300|ensembl:ENSG00000117226(gene)|ensembl:ENST00000370481(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	go:"GO:0031982"(vesicle)	-	-	figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:DZ/4GjzK0RWder8XbSKaDpHUCYs9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:yfftF4Z5y1ThWAfNt6B2yy18PCo	false	venus c-terminal fragment:n-n	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96PP9	uniprotkb:P32455	intact:EBI-20840650|ensembl:ENSP00000359490|uniprotkb:B2R630|uniprotkb:Q05D63|uniprotkb:Q6NSL0|uniprotkb:Q86T99	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp4_human(display_long)|uniprotkb:GTP-binding protein 4(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 4(gene name synonym)|uniprotkb:GBP4(gene name)|psi-mi:GBP4(display_short)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472618|imex:IM-28522-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162654(gene)|ensembl:ENST00000355754(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|reactome:R-HSA-877300|refseq:NP_443173.2	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	go:"GO:0031982"(vesicle)	-	-	figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:pFjhPH/83j+kU9zCy8cxRQ/lTTA9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:GdRsmNBA3OR0hO1EPB/+zG9HTtM	false	venus c-terminal fragment:n-n	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96PP9	uniprotkb:P32456	intact:EBI-20840650|ensembl:ENSP00000359490|uniprotkb:B2R630|uniprotkb:Q05D63|uniprotkb:Q6NSL0|uniprotkb:Q86T99	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp4_human(display_long)|uniprotkb:GTP-binding protein 4(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 4(gene name synonym)|uniprotkb:GBP4(gene name)|psi-mi:GBP4(display_short)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472626|imex:IM-28522-107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162654(gene)|ensembl:ENST00000355754(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|reactome:R-HSA-877300|refseq:NP_443173.2	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	go:"GO:0048471"(perinuclear region of cytoplasm)	-	-	figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:pFjhPH/83j+kU9zCy8cxRQ/lTTA9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:2B5RuFb/4rnyII67yHH33YmOfyM	false	venus c-terminal fragment:n-n	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9H0R5	uniprotkb:P32456	intact:EBI-2798916|uniprotkb:A2A317|uniprotkb:B2RTW0|uniprotkb:Q05D54|uniprotkb:Q9NV33|uniprotkb:A6NF86|uniprotkb:Q5T8L9|uniprotkb:Q5T8L8|uniprotkb:Q6P3V3|uniprotkb:F8UW81|ensembl:ENSP00000359512	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp3_human(display_long)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GBP3(gene name)|psi-mi:GBP3(display_short)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472637|imex:IM-28522-79	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306110.1|refseq:NP_060754.2|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q9H0R5|reactome:R-HSA-877300|ensembl:ENSG00000117226(gene)|ensembl:ENST00000370481(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	go:"GO:0048471"(perinuclear region of cytoplasm)	-	-	figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:DZ/4GjzK0RWder8XbSKaDpHUCYs9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:CyACL6qFaWnjePhzvLQCFQ210o4	false	venus c-terminal fragment:n-n	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9H0R5	uniprotkb:Q96PP8	intact:EBI-2798916|uniprotkb:A2A317|uniprotkb:B2RTW0|uniprotkb:Q05D54|uniprotkb:Q9NV33|uniprotkb:A6NF86|uniprotkb:Q5T8L9|uniprotkb:Q5T8L8|uniprotkb:Q6P3V3|uniprotkb:F8UW81|ensembl:ENSP00000359512	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp3_human(display_long)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GBP3(gene name)|psi-mi:GBP3(display_short)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472646|imex:IM-28522-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306110.1|refseq:NP_060754.2|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q9H0R5|reactome:R-HSA-877300|ensembl:ENSG00000117226(gene)|ensembl:ENST00000370481(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	go:"GO:0005794"(Golgi apparatus)	-	-	figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:DZ/4GjzK0RWder8XbSKaDpHUCYs9606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:GtN5LkWovAIqx2/wtGeRgavjXBs	false	venus c-terminal fragment:n-n	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96PP9	uniprotkb:Q96PP8	intact:EBI-20840650|ensembl:ENSP00000359490|uniprotkb:B2R630|uniprotkb:Q05D63|uniprotkb:Q6NSL0|uniprotkb:Q86T99	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp4_human(display_long)|uniprotkb:GTP-binding protein 4(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 4(gene name synonym)|uniprotkb:GBP4(gene name)|psi-mi:GBP4(display_short)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26472655|imex:IM-28522-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162654(gene)|ensembl:ENST00000355754(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|reactome:R-HSA-877300|refseq:NP_443173.2	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	go:"GO:0005794"(Golgi apparatus)	-	-	figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/26	rogid:pFjhPH/83j+kU9zCy8cxRQ/lTTA9606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:+2F0Cq0Y1H2lwwwXhHyTTucfRQs	false	venus c-terminal fragment:n-n	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96PP8	uniprotkb:P32456	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26493577|imex:IM-28522-109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	go:"GO:0005794"(Golgi apparatus)	-	-	figure legend:Supp. Fig. 7A|comment:"Treatment with GGTI (geranylgeranyl transferase type I inhibitor) resulted in a diffuse localization pattern for GBP-2/GBP-5 heterodimers ."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/11/24	2020/11/27	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:odwW+Mpg0h/xtdQvJqObd0Bgdfk	false	venus c-terminal fragment:n-n	venus n-terminal fragment:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P32456	uniprotkb:P32456	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	intact:EBI-714388|ensembl:ENSP00000359497|ensembl:ENSP00000434282|uniprotkb:Q86TB0|uniprotkb:Q6GPH0|uniprotkb:Q6IAU2	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:gbp2_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 2(gene name synonym)|uniprotkb:GTP-binding protein 2(gene name synonym)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:Interferon-induced guanylate-binding protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454366|imex:IM-28522-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:6VKJ|rcsb pdb:7E58|reactome:R-HSA-877300|reactome:R-HSA-909733|ensembl:ENSG00000162645(gene)|ensembl:ENST00000370466(transcript)|ensembl:ENST00000464839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|refseq:NP_004111.2	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/11/24	2020/11/25	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rogid:RwN35svId7qV9XCud4YX856gOCo9606	rigid:DhRJPTlMOqewZWwepR+fTPKZ3VA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32455	uniprotkb:P32455	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454358|imex:IM-28522-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/11/24	2020/11/25	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rigid:6B0DBE/CvuH+H1gqYfA6RT1Kqrs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96PP8	uniprotkb:Q96PP8	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	intact:EBI-749932|uniprotkb:B2RCE1|uniprotkb:Q86TM5|ensembl:ENSP00000359488	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:gbp5_human(display_long)|uniprotkb:Guanine nucleotide-binding protein 5(gene name synonym)|uniprotkb:GTP-binding protein 5(gene name synonym)|uniprotkb:GBP-TA antigen(gene name synonym)|uniprotkb:GBP5(gene name)|psi-mi:GBP5(display_short)|uniprotkb:UNQ2427/PRO4987(orf name)	psi-mi:"MI:0018"(two hybrid)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454374|imex:IM-28522-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	refseq:NP_001127958.1|refseq:NP_443174.1|ensembl:ENSG00000154451(gene)|ensembl:ENST00000370459(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q96PP8|rcsb pdb:7CKF|rcsb pdb:7E59|rcsb pdb:7E5A|reactome:R-HSA-877300|interpro:IPR015894(Guanylate-binding protein, N-terminal)	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/11/24	2020/11/25	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rogid:oeKbs0b2DOTZqVLfDuJKrH6tua89606	rigid:QPEi1jcghoYpHMrlZd14ekA7jBA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H0R5	uniprotkb:Q9H0R5	intact:EBI-2798916|uniprotkb:A2A317|uniprotkb:B2RTW0|uniprotkb:Q05D54|uniprotkb:Q9NV33|uniprotkb:A6NF86|uniprotkb:Q5T8L9|uniprotkb:Q5T8L8|uniprotkb:Q6P3V3|uniprotkb:F8UW81|ensembl:ENSP00000359512	intact:EBI-2798916|uniprotkb:A2A317|uniprotkb:B2RTW0|uniprotkb:Q05D54|uniprotkb:Q9NV33|uniprotkb:A6NF86|uniprotkb:Q5T8L9|uniprotkb:Q5T8L8|uniprotkb:Q6P3V3|uniprotkb:F8UW81|ensembl:ENSP00000359512	psi-mi:gbp3_human(display_long)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GBP3(gene name)|psi-mi:GBP3(display_short)	psi-mi:gbp3_human(display_long)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GBP3(gene name)|psi-mi:GBP3(display_short)	psi-mi:"MI:0018"(two hybrid)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454383|imex:IM-28522-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001306110.1|refseq:NP_060754.2|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q9H0R5|reactome:R-HSA-877300|ensembl:ENSG00000117226(gene)|ensembl:ENST00000370481(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)	refseq:NP_001306110.1|refseq:NP_060754.2|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|mint:Q9H0R5|reactome:R-HSA-877300|ensembl:ENSG00000117226(gene)|ensembl:ENST00000370481(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/11/24	2020/11/25	rogid:DZ/4GjzK0RWder8XbSKaDpHUCYs9606	rogid:DZ/4GjzK0RWder8XbSKaDpHUCYs9606	rigid:z3T/lZbhW5rcZOegEA0XiG95Gcs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96PP9	uniprotkb:Q96PP9	intact:EBI-20840650|ensembl:ENSP00000359490|uniprotkb:B2R630|uniprotkb:Q05D63|uniprotkb:Q6NSL0|uniprotkb:Q86T99	intact:EBI-20840650|ensembl:ENSP00000359490|uniprotkb:B2R630|uniprotkb:Q05D63|uniprotkb:Q6NSL0|uniprotkb:Q86T99	psi-mi:gbp4_human(display_long)|uniprotkb:GTP-binding protein 4(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 4(gene name synonym)|uniprotkb:GBP4(gene name)|psi-mi:GBP4(display_short)	psi-mi:gbp4_human(display_long)|uniprotkb:GTP-binding protein 4(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 4(gene name synonym)|uniprotkb:GBP4(gene name)|psi-mi:GBP4(display_short)	psi-mi:"MI:0018"(two hybrid)	Britzen-Laurent et al. (2009)	imex:IM-28522|pubmed:21151871	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26454387|imex:IM-28522-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000162654(gene)|ensembl:ENST00000355754(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|reactome:R-HSA-877300|refseq:NP_443173.2	ensembl:ENSG00000162654(gene)|ensembl:ENST00000355754(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|reactome:R-HSA-877300|refseq:NP_443173.2	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/11/24	2020/11/25	rogid:pFjhPH/83j+kU9zCy8cxRQ/lTTA9606	rogid:pFjhPH/83j+kU9zCy8cxRQ/lTTA9606	rigid:JEALETSwChAF6Z6cwR+hE4m9KpE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)