#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9BXX0	uniprotkb:O00602-PRO_0000009136	intact:EBI-11740176|uniprotkb:B2RMY3|uniprotkb:Q8NBH3|uniprotkb:Q96JQ4|ensembl:ENSP00000254528	intact:EBI-11784425	psi-mi:emil2_human(display_long)|uniprotkb:EMILIN2(gene name)|psi-mi:EMILIN2(display_short)|uniprotkb:Elastin microfibril interface-located protein 2(gene name synonym)|uniprotkb:Protein FOAP-10(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357441|imex:IM-28428-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114437.2|ensembl:ENSG00000132205(gene)|ensembl:ENST00000254528(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0007155"(cell adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR011489(EMI)|reactome:R-HSA-2129379|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:YncpkDHFOyL1VjUqbv8fJS1EUAo9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:bjsju9bAEXSXiktC9KXhHHU8V3g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15552	uniprotkb:O00602-PRO_0000009136	intact:EBI-2833872|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5|ensembl:ENSP00000246549|ensembl:ENSP00000473159	intact:EBI-11784425	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357446|imex:IM-28428-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|ensembl:ENSG00000126262(gene)|ensembl:ENST00000246549(transcript)|ensembl:ENST00000599180(transcript)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0002879"(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0090276"(regulation of peptide hormone secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:4dhdSPbu2QfaF+AfCo91/6irf6Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00602	uniprotkb:O00602-PRO_0000009136	intact:EBI-5282479|uniprotkb:Q5VYV5|uniprotkb:Q92596|ensembl:ENSP00000360871	intact:EBI-11784425	psi-mi:fcn1_human(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357450|imex:IM-28428-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001994.2|ensembl:ENSG00000085265(gene)|ensembl:ENST00000371806(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033691"(sialic acid binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:O00602|rcsb pdb:2D39|rcsb pdb:2JHH|rcsb pdb:2JHI|rcsb pdb:2JHK|rcsb pdb:2JHL|rcsb pdb:2JHM|rcsb pdb:2WNP|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|reactome:R-HSA-6798695	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:7qu36ZaWgX+GyX+QUbGj0RGrp4U9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:6+VY/KYRa2O5MyFeUJUip6otPws	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P80217	uniprotkb:O00602-PRO_0000009136	intact:EBI-2115067|uniprotkb:Q92984|uniprotkb:Q99537|uniprotkb:Q9BV98|uniprotkb:C9JGX1|ensembl:ENSP00000394579	intact:EBI-11784425	psi-mi:in35_human(display_long)|uniprotkb:IFI35(gene name)|psi-mi:IFI35(display_short)|uniprotkb:IFP35(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357454|imex:IM-28428-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005524.2|refseq:NP_001317159.1|ensembl:ENSG00000068079(gene)|ensembl:ENST00000415816(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034460|mint:P80217|reactome:R-HSA-909733	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:IR0w7n2R0RaTZ9n8A3cWylc2Jd49606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:419nyyFn42XR4SPQyyJ96TL4yek	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O14618	uniprotkb:O00602-PRO_0000009136	intact:EBI-11668690|uniprotkb:Q2M366|uniprotkb:Q8NEV0|ensembl:ENSP00000436318	intact:EBI-11784425	psi-mi:ccs_human(display_long)|uniprotkb:CCS(gene name)|psi-mi:CCS(display_short)|uniprotkb:Superoxide dismutase copper chaperone(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357458|imex:IM-28428-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005116.1|ensembl:ENSG00000173992(gene)|ensembl:ENST00000533244(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045296"(cadherin binding)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036163|interpro:IPR036423|mint:O14618|rcsb pdb:1DO5|rcsb pdb:2CRL|rcsb pdb:2RSQ|rcsb pdb:6FN8|rcsb pdb:6FOL|rcsb pdb:6FON|rcsb pdb:6FP6|reactome:R-HSA-3299685	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:r5pGUXbIewnEFuTqrKn78aG7N309606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:voOuH3InhSbs0djhSnoudqDImVY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O00754	uniprotkb:O00602-PRO_0000009136	intact:EBI-2906023|ensembl:ENSP00000395473|uniprotkb:O15330|uniprotkb:Q16680|uniprotkb:Q93094|uniprotkb:Q9BW13|uniprotkb:G5E928	intact:EBI-11784425	psi-mi:ma2b1_human(display_long)|uniprotkb:MAN2B1(gene name)|psi-mi:MAN2B1(display_short)|uniprotkb:LAMAN(gene name synonym)|uniprotkb:MANB(gene name synonym)|uniprotkb:Lysosomal acid alpha-mannosidase(gene name synonym)|uniprotkb:Mannosidase alpha class 2B member 1(gene name synonym)|uniprotkb:Mannosidase alpha-B(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357462|imex:IM-28428-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000104774(gene)|ensembl:ENST00000456935(transcript)|go:"GO:0004559"(alpha-mannosidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000602(Glycoside hydrolase, family 38, core)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR011682(Glycosyl hydrolases 38, C-terminal)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR015341(Glycoside hydrolase, family 38, central region)|interpro:IPR027291|interpro:IPR028995|interpro:IPR037094|interpro:IPR041147|go:"GO:0006013"(mannose metabolic process)|reactome:R-HSA-8853383|reactome:R-HSA-6798695|refseq:NP_000519.2|refseq:NP_001166969.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:IU+SVFkhTpsEd+JE2vHUfD04IS49606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:odrhCPMN9JzbGl19AWYsfBuBErc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P28676	uniprotkb:O00602-PRO_0000009136	intact:EBI-947242|uniprotkb:Q53TB5|uniprotkb:Q59EP3|uniprotkb:B2R5X3|ensembl:ENSP00000394842	intact:EBI-11784425	psi-mi:gran_human(display_long)|uniprotkb:GCA(gene name)|psi-mi:GCA(display_short)|uniprotkb:GCL(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357478|imex:IM-28428-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036330.1|dip:DIP-41437N|ensembl:ENSG00000115271(gene)|ensembl:ENST00000437150(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1F4O|rcsb pdb:1F4Q|rcsb pdb:1K94|rcsb pdb:1K95|reactome:R-HSA-6798695	intact:EBI-5282479(chain-parent)	-	crc64:88CA4DDF835AFFE4	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:I1zdQPwDUFrBGazaVREgC7nqxok9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:udUNNnI/m3HQyUgWUH2XxNgVWjs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55084	uniprotkb:O00602-PRO_0000009136	intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0	intact:EBI-11784425	psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357487|imex:IM-28428-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:1+i1Nb3Hk26y6WdRMaVVYjPJVU8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IXJ9	uniprotkb:O00602-PRO_0000009136	intact:EBI-1646500|uniprotkb:Q5JWS9|uniprotkb:Q8IYY7|uniprotkb:Q9H466|uniprotkb:Q9NQF8|uniprotkb:Q9UFJ0|uniprotkb:Q9UFP8|uniprotkb:Q9Y2I4|uniprotkb:B2RP59|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978	intact:EBI-11784425	psi-mi:asxl1_human(display_long)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym)|uniprotkb:Additional sex combs-like protein 1(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357492|imex:IM-28428-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_056153.2|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978|dip:DIP-46910N|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035359"(negative regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035517"(PR-DUB complex)|go:"GO:0035522"(monoubiquitinated histone H2A deubiquitination)|go:"GO:0035564"(regulation of kidney size)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0048539"(bone marrow development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0060430"(lung saccule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|interpro:IPR007759(DNA-directed RNA polymerase delta subunit)|interpro:IPR024811|interpro:IPR024815|interpro:IPR026905|interpro:IPR028020|interpro:IPR044867|reactome:R-HSA-5689603|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:ztLu4XxKkU/0eMuxJ41O3YARNew	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6DKI7	uniprotkb:O00602-PRO_0000009136	intact:EBI-17964309|uniprotkb:D6W5U9|uniprotkb:Q9BVK3|ensembl:ENSP00000316675	intact:EBI-11784425	psi-mi:pvrig_human(display_long)|uniprotkb:CD112 receptor(gene name synonym)|uniprotkb:Poliovirus receptor-related immunoglobulin domain-containing protein(gene name synonym)|uniprotkb:PVRIG(gene name)|psi-mi:PVRIG(display_short)|uniprotkb:C7orf15(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357513|imex:IM-28428-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076975.2|refseq:XP_011514877.1|ensembl:ENSG00000213413(gene)|ensembl:ENST00000317271(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|interpro:IPR034452	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:mI+pH3CQwQcUBIrKM9rIq/GhFbc9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:6YjjEpRnL/Ko7HSCeHDjecRznvM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y6E0	uniprotkb:O00602-PRO_0000009136	intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809	intact:EBI-11784425	psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357518|imex:IM-28428-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:etyICkbBq+QMxx/N2zXniFy+2Z8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23945	uniprotkb:O00602-PRO_0000009136	intact:EBI-848239|uniprotkb:Q4QRJ3|uniprotkb:Q16225|intact:EBI-848267|uniprotkb:A8K947|uniprotkb:Q4ZFZ2|uniprotkb:Q53RW2|uniprotkb:Q05AH0|uniprotkb:G5CBS7|uniprotkb:G5E967|uniprotkb:J3KQ00|uniprotkb:A0A0A0MSC5|ensembl:ENSP00000306780	intact:EBI-11784425	psi-mi:fshr_human(display_long)|uniprotkb:Follitropin receptor(gene name synonym)|uniprotkb:FSHR(gene name)|psi-mi:FSHR(display_short)|uniprotkb:LGR1(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357522|imex:IM-28428-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000136.2|refseq:NP_852111.2|dip:DIP-35605N|ensembl:ENSG00000170820(gene)|ensembl:ENST00000304421(transcript)|go:"GO:0004963"(follicle-stimulating hormone receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007292"(female gamete generation)|go:"GO:0008406"(gonad development)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043235"(receptor complex)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR002131(Glycoprotein hormone receptor)|interpro:IPR002272(Follicle-stimulating hormone receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR024635|interpro:IPR026906|rcsb pdb:1XUN|rcsb pdb:1XWD|rcsb pdb:4AY9|rcsb pdb:4MQW|reactome:R-HSA-375281|reactome:R-HSA-418555|reactome:R-HSA-9660821	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:/X+tlZ4lvnJkOx2ze67Y3IzCUcw9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:pfc2GVoNdBDvJQbCg505XTqXi6g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q2QGD7	uniprotkb:O00602-PRO_0000009136	intact:EBI-1538838|uniprotkb:Q7L3L1|uniprotkb:Q8NAU2|uniprotkb:C5J0H9|uniprotkb:Q6DKI8|ensembl:ENSP00000374359|intact:EBI-28981670	intact:EBI-11784425	psi-mi:zxdc_human(display_long)|uniprotkb:ZXDC(gene name)|psi-mi:ZXDC(display_short)|uniprotkb:ZXDL(gene name synonym)|uniprotkb:ZXD-like zinc finger protein(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357533|imex:IM-28428-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035743.1|refseq:NP_079388.3|ensembl:ENST00000336332|ensembl:ENSP00000337694|ensembl:ENSP00000374359|ensembl:ENSG00000070476(gene)|ensembl:ENST00000389709(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2QGD7	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:2oqRV2O8vmW9f6FeX+td6cvhyNI9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:6ywqjtHzSY5Tj84Qm7rKlMi2X2g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P52566	uniprotkb:O00602-PRO_0000009136	intact:EBI-2806617|uniprotkb:B5BU79|ensembl:ENSP00000228945|ensembl:ENSP00000440560|ensembl:ENSP00000444860	intact:EBI-11784425	psi-mi:gdir2_human(display_long)|uniprotkb:GDIA2(gene name synonym)|uniprotkb:GDID4(gene name synonym)|uniprotkb:RAP1GN1(gene name synonym)|uniprotkb:Ly-GDI(gene name synonym)|uniprotkb:Rho-GDI beta(gene name synonym)|uniprotkb:ARHGDIB(gene name)|psi-mi:ARHGDIB(display_short)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357554|imex:IM-28428-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001166.3|ensembl:ENSG00000111348(gene)|ensembl:ENST00000541546(transcript)|ensembl:ENST00000541644(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071461"(cellular response to redox state)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|ensembl:ENST00000228945(transcript)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52566|rcsb pdb:1DS6|rcsb pdb:5H1D|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:NP_001308349.1|refseq:NP_001308350.1|refseq:NP_001308351.1|refseq:NP_001308352.1|dip:DIP-40959N	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:uiFgGyiT2vBDU0XIRX2ix/bDmHw9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:lUcPC+t6Key0KJo0GsPP2McPB14	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NNW5	uniprotkb:O00602-PRO_0000009136	intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389	intact:EBI-11784425	psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357558|imex:IM-28428-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:W/U4jQdZ40B4/bh2ulia0Y0Ml4I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40617	uniprotkb:O00602-PRO_0000009136	intact:EBI-2875746|ensembl:ENSP00000349250|ensembl:ENSP00000379897|ensembl:ENSP00000379898|ensembl:ENSP00000379899|ensembl:ENSP00000385236|ensembl:ENSP00000498350|uniprotkb:A4D119|uniprotkb:P80418|uniprotkb:Q49AF5	intact:EBI-11784425	psi-mi:arl4a_human(display_long)|uniprotkb:ARL4A(gene name)|psi-mi:ARL4A(display_short)|uniprotkb:ARL4(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357562|imex:IM-28428-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000122644(gene)|ensembl:ENST00000356797(transcript)|ensembl:ENST00000396662(transcript)|ensembl:ENST00000396663(transcript)|ensembl:ENST00000396664(transcript)|ensembl:ENST00000404894(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0050873"(brown fat cell differentiation)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|ensembl:ENST00000651779(transcript)|refseq:NP_001032241.1|refseq:NP_001182325.1|refseq:NP_005729.1|refseq:NP_997625.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:HeYXLZVghtF0zlvC7YW+RkNYMt09606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:t2dXUXfS82UIH7b9MkK2YK461o0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q504T8	uniprotkb:O00602-PRO_0000009136	intact:EBI-7153979|intact:EBI-28985054|ensembl:ENSP00000300952|ensembl:ENSP00000467679|uniprotkb:Q96BW8|intact:MINT-6775185	intact:EBI-11784425	psi-mi:midn_human(display_long)|uniprotkb:MIDN(gene name)|psi-mi:MIDN(display_short)|uniprotkb:Midbrain nucleolar protein(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357566|imex:IM-28428-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000300952|ensembl:ENSP00000467679|ensembl:ENSG00000167470(gene)|ensembl:ENST00000300952(transcript)|ensembl:ENST00000591446(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0019900"(kinase binding)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0046676"(negative regulation of insulin secretion)|interpro:IPR039336|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|refseq:NP_796375.3	intact:EBI-5282479(chain-parent)	-	function:May be involved in regulation of genes related to neurogenesis in the nucleolus|comment:mint|comment:homomint	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:/zSEvdze4tm+58+3IFoJhdZNLEg9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:XvRLZiKiPjkc23TUxfhFPYzB42I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A6NC98	uniprotkb:O00602-PRO_0000009136	intact:EBI-347573|uniprotkb:B5MDM2|uniprotkb:A5D8Y5|uniprotkb:Q05BL2|uniprotkb:Q6RUV3|uniprotkb:Q8N1Q6|uniprotkb:Q8NF44|uniprotkb:Q9H0H1|intact:EBI-2802028|ensembl:ENSP00000349238	intact:EBI-11784425	psi-mi:cc88b_human(display_long)|uniprotkb:CCDC88B(gene name)|psi-mi:CCDC88B(display_short)|uniprotkb:BRLZ(gene name synonym)|uniprotkb:Brain leucine zipper domain-containing protein(gene name synonym)|uniprotkb:Hook-related protein 3(gene name synonym)|uniprotkb:Gipie(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357612|imex:IM-28428-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115627.6|ensembl:ENSG00000168071(gene)|ensembl:ENST00000356786(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051959"(dynein light intermediate chain binding)|interpro:IPR036872|interpro:IPR043936	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:s3J2pQABqQHFONLVjshSCCTTmSc9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:VO8zASKquYUZIhRxJFjwF052Xb4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P23528	uniprotkb:O00602-PRO_0000009136	intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629|ensembl:ENSP00000432660	intact:EBI-11784425	psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357624|imex:IM-28428-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005498.1|ensembl:ENSG00000172757(gene)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|ensembl:ENST00000308162(transcript)|ensembl:ENST00000525451(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009615"(response to virus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0031258"(lamellipodium membrane)|dip:DIP-33000N	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:v7xV7MnC47qnIDoxJPeCdtbA5Y8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06702	uniprotkb:O00602-PRO_0000009136	intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727	intact:EBI-11784425	psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357635|imex:IM-28428-85	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:CFmh8RkSkhiFlObVlWA5BpFCtW8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17612	uniprotkb:O00602-PRO_0000009136	intact:EBI-476586|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9|ensembl:ENSP00000309591|ensembl:ENSP00000499940	intact:EBI-11784425	psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357639|imex:IM-28428-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002721.1|refseq:NP_997401.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|ensembl:ENSG00000072062(gene)|ensembl:ENSG00000288516(gene)|ensembl:ENST00000308677(transcript)|ensembl:ENST00000673550(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:0046827"(positive regulation of protein export from nucleus)|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|rcsb pdb:3MVJ|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3NX8|interpro:IPR044109|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|mint:P17612|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:2GU8|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-380320|reactome:R-HSA-8963896|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9010642|refseq:NP_001291278.1|dip:DIP-33878N	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:cjLVEuaoZCKIQG28BsHvvN6dKic	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q15942	uniprotkb:O00602-PRO_0000009136	intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7	intact:EBI-11784425	psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357643|imex:IM-28428-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:la0bD71Ed/oLuf12UEWufBnJX/M	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96BY9	uniprotkb:O00602-PRO_0000009136	intact:EBI-722561|uniprotkb:Q53HE8|uniprotkb:Q9UNZ3|uniprotkb:Q9Y683|uniprotkb:D3DSU7|uniprotkb:B3KQQ4|uniprotkb:B7Z9J1|uniprotkb:H9MHJ8|uniprotkb:H9MHJ9|ensembl:ENSP00000256255	intact:EBI-11784425	psi-mi:saraf_human(display_long)|uniprotkb:SARAF(gene name)|psi-mi:SARAF(display_short)|uniprotkb:HBV X-transactivated gene 3 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 3(gene name synonym)|uniprotkb:Protein FOAP-7(gene name synonym)|uniprotkb:TMEM66(gene name synonym)|uniprotkb:Transmembrane protein 66(gene name synonym)|uniprotkb:XTP3(gene name synonym)|uniprotkb:HSPC035(orf name)|uniprotkb:NPD003(orf name)|uniprotkb:PSEC0019(orf name)|uniprotkb:UNQ1967/PRO4499(orf name)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357647|imex:IM-28428-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271168.1|refseq:NP_057211.4|ensembl:ENSG00000133872(gene)|ensembl:ENST00000256255(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR009567(Protein of unknown function DUF1183)|rcsb pdb:6O2U|rcsb pdb:6O2V|rcsb pdb:6O2W	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:qxgObw0slMLCKeF+2YAHTxjlkQk9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:1eXk4ubieg80JG5LtrEX1WoH4j0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14703	uniprotkb:O00602-PRO_0000009136	intact:EBI-2829953|uniprotkb:Q24JQ2|uniprotkb:Q9UF67|uniprotkb:A8K6V8|ensembl:ENSP00000344223	intact:EBI-11784425	psi-mi:mbtp1_human(display_long)|uniprotkb:MBTPS1(gene name)|psi-mi:MBTPS1(display_short)|uniprotkb:KIAA0091(gene name synonym)|uniprotkb:S1P(gene name synonym)|uniprotkb:SKI1(gene name synonym)|uniprotkb:Endopeptidase S1P(gene name synonym)|uniprotkb:Subtilisin/kexin-isozyme 1(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357651|imex:IM-28428-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003782.1|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006508"(proteolysis)|go:"GO:0007040"(lysosome organization)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0060627"(regulation of vesicle-mediated transport)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023828|interpro:IPR034185|interpro:IPR036852|reactome:R-HSA-1655829|reactome:R-HSA-381033|reactome:R-HSA-381426|reactome:R-HSA-8874211|reactome:R-HSA-8957275|reactome:R-HSA-8963889|go:"GO:0004252"(serine-type endopeptidase activity)|ensembl:ENSG00000140943(gene)|ensembl:ENST00000343411(transcript)|go:"GO:0000139"(Golgi membrane)	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:Szqa2FHer6aXjbHXgnXIhawbnNM9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:xnCQn6YiLwqfvkhYepSZ/93W/5s	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96HC4	uniprotkb:O00602-PRO_0000009136	intact:EBI-751267|uniprotkb:Q8WVK0|uniprotkb:O60705|uniprotkb:A8K6F9|uniprotkb:Q5UW38|uniprotkb:D6RB78|uniprotkb:E9PBF5|uniprotkb:Q56VN4|ensembl:ENSP00000321746	intact:EBI-11784425	psi-mi:pdli5_human(display_long)|uniprotkb:Enigma homolog(gene name synonym)|uniprotkb:Enigma-like PDZ and LIM domains protein(gene name synonym)|uniprotkb:PDLIM5(gene name)|psi-mi:PDLIM5(display_short)|uniprotkb:L9(orf name)|uniprotkb:ENH(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357655|imex:IM-28428-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001011515.1|refseq:NP_001011516.1|refseq:NP_006448.4|refseq:NP_001243358.1|mint:Q96HC4|rcsb pdb:2DAR|rcsb pdb:2UZC|reactome:R-HSA-6794361|interpro:IPR036034|ensembl:ENSG00000163110(gene)|ensembl:ENST00000317968(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0042805"(actinin binding)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061061"(muscle structure development)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|go:"GO:0005829"(cytosol)|dip:DIP-34898N	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:Ngp310yfoOv8KaxchoUc39mj5HE9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:q5LXZ5eABof+KnjnB+AbCjLLpkI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H2X8	uniprotkb:O00602-PRO_0000009136	intact:EBI-2870177|uniprotkb:Q8TBD7|uniprotkb:Q9NYL0|ensembl:ENSP00000238609|ensembl:ENSP00000482521	intact:EBI-11784425	psi-mi:i27l2_human(display_long)|uniprotkb:IFI27L2(gene name)|psi-mi:IFI27L2(display_short)|uniprotkb:FAM14A(gene name synonym)|uniprotkb:TLH29(gene name synonym)|uniprotkb:Interferon-stimulated gene 12b protein(gene name synonym)|uniprotkb:Protein TLH29(gene name synonym)|uniprotkb:pIFI27-like protein(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357659|imex:IM-28428-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114425.1|ensembl:ENSG00000119632(gene)|ensembl:ENSG00000276879(gene)|ensembl:ENST00000238609(transcript)|ensembl:ENST00000619362(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR009311(Interferon-induced 6-16)|interpro:IPR038213	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:r2zp+wZBIWQcjGYGeiMdEV4Wrb49606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:6KLUFiJDCDpxo0LQSL8SoxdYiZQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UBK5	uniprotkb:O00602-PRO_0000009136	intact:EBI-2801937|uniprotkb:Q9Y3Y0|uniprotkb:Q9UBS1|ensembl:ENSP00000246551	intact:EBI-11784425	psi-mi:hcst_human(display_long)|uniprotkb:DAP10(gene name synonym)|uniprotkb:KAP10(gene name synonym)|uniprotkb:PIK3AP(gene name synonym)|uniprotkb:DNAX-activation protein 10(gene name synonym)|uniprotkb:Membrane protein DAP10(gene name synonym)|uniprotkb:Transmembrane adapter protein KAP10(gene name synonym)|uniprotkb:UNQ587/PRO1157(orf name)|uniprotkb:HCST(gene name)|psi-mi:HCST(display_short)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357663|imex:IM-28428-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001007470.1|refseq:NP_055081.1|ensembl:ENSG00000126264(gene)|ensembl:ENST00000246551(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009986"(cell surface)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0050776"(regulation of immune response)|interpro:IPR009861(DAP10 membrane)|reactome:R-HSA-198933	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:l3Y4nH5EswUi0NoqaaE0roDqEvQ9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:cLSZ9XtHTJENWXrioVk0fRSJ39U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P02795	uniprotkb:O00602-PRO_0000009136	intact:EBI-996616|uniprotkb:Q2HXR9|uniprotkb:Q53XT9|uniprotkb:Q14823|ensembl:ENSP00000245185	intact:EBI-11784425	psi-mi:mt2_human(display_long)|uniprotkb:Metallothionein-II(gene name synonym)|uniprotkb:Metallothionein-2A(gene name synonym)|uniprotkb:MT2A(gene name)|psi-mi:MT2A(display_short)|uniprotkb:CES1(gene name synonym)|uniprotkb:MT2(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357667|imex:IM-28428-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005944.1|ensembl:ENSG00000125148(gene)|ensembl:ENST00000245185(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0036018"(cellular response to erythropoietin)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071294"(cellular response to zinc ion)|interpro:IPR000006(Metallothionein, vertebrate)|interpro:IPR003019(Metallothionein superfamily, eukaryotic)|interpro:IPR017854(Metallothionein superfamily)|interpro:IPR018064|interpro:IPR023587|mint:P02795|rcsb pdb:1MHU|rcsb pdb:2MHU|go:"GO:0006882"(cellular zinc ion homeostasis)|reactome:R-HSA-877300|reactome:R-HSA-5661231|dip:DIP-35232N	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:3adUmT5As6Rn1isYoH+jMsFKEgU9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:e/KzMoVMlc+4e2PtAOgCCfL8KpM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q06643	uniprotkb:O00602-PRO_0000009136	intact:EBI-524217|uniprotkb:P78370|uniprotkb:Q99761|ensembl:ENSP00000365285|ensembl:ENSP00000372985|ensembl:ENSP00000393693|ensembl:ENSP00000395102|ensembl:ENSP00000398741|ensembl:ENSP00000404014|ensembl:ENSP00000404450|ensembl:ENSP00000410481|uniprotkb:Q52LU8	intact:EBI-11784425	psi-mi:tnfc_human(display_long)|uniprotkb:Tumor necrosis factor C(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 3(gene name synonym)|uniprotkb:LTB(gene name)|psi-mi:LTB(display_short)|uniprotkb:TNFC(gene name synonym)|uniprotkb:TNFSF3(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357671|imex:IM-28428-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000204487(gene)|ensembl:ENSG00000206437(gene)|ensembl:ENSG00000223448(gene)|ensembl:ENSG00000227507(gene)|ensembl:ENSG00000231314(gene)|ensembl:ENSG00000236237(gene)|ensembl:ENSG00000236925(gene)|ensembl:ENSG00000238114(gene)|ensembl:ENST00000376117(transcript)|ensembl:ENST00000383493(transcript)|ensembl:ENST00000420402(transcript)|ensembl:ENST00000421268(transcript)|ensembl:ENST00000429299(transcript)|ensembl:ENST00000444479(transcript)|ensembl:ENST00000456113(transcript)|ensembl:ENST00000457552(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010467"(gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0043588"(skin development)|go:"GO:0048535"(lymph node development)|interpro:IPR002961(Tumour necrosis factor c/lymphotoxin-beta)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|rcsb pdb:4MXW|reactome:R-HSA-5668541|reactome:R-HSA-5676594|go:"GO:0005102"(signaling receptor binding)|refseq:NP_002332.1|refseq:NP_033666.1|dip:DIP-2996N	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:rf1zq2ooNyfvllGuon3bemfZU549606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:Yn0lfNvruLxeddcUTsQlcq0cKVY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NPA2	uniprotkb:O00602-PRO_0000009136	intact:EBI-12346397|ensembl:ENSP00000337816|uniprotkb:D3DUA8|uniprotkb:Q9H3Q0	intact:EBI-11784425	psi-mi:mmp25_human(display_long)|uniprotkb:MMP25(gene name)|psi-mi:MMP25(display_short)|uniprotkb:Leukolysin(gene name synonym)|uniprotkb:MMP20(gene name synonym)|uniprotkb:MMPL1(gene name synonym)|uniprotkb:MT6MMP(gene name synonym)|uniprotkb:Membrane-type matrix metalloproteinase 6(gene name synonym)|uniprotkb:Membrane-type-6 matrix metalloproteinase(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357698|imex:IM-28428-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000008516(gene)|ensembl:ENST00000336577(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006954"(inflammatory response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0060022"(hard palate development)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR018487|interpro:IPR021190|interpro:IPR024079|interpro:IPR033739|interpro:IPR036375|reactome:R-HSA-1592389|reactome:R-HSA-6798695|refseq:NP_071913.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:SE0WQPRMWbeDC9M8jirqfsT400E9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:hl9DFOONxInnbQW0UF6ZilbiCJk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BSV6	uniprotkb:O00602-PRO_0000009136	intact:EBI-11017932|uniprotkb:B0V3J1|uniprotkb:A6NNB1|uniprotkb:Q9H6H5|uniprotkb:Q9BVT1|ensembl:ENSP00000305524|ensembl:ENSP00000379667|ensembl:ENSP00000379671|ensembl:ENSP00000397402|ensembl:ENSP00000400743|ensembl:ENSP00000477766|ensembl:ENSP00000478156|ensembl:ENSP00000478622|ensembl:ENSP00000479576|ensembl:ENSP00000479654|ensembl:ENSP00000480422|ensembl:ENSP00000480503|ensembl:ENSP00000480899|ensembl:ENSP00000480964|ensembl:ENSP00000481068|ensembl:ENSP00000481374|ensembl:ENSP00000481639|ensembl:ENSP00000482084|ensembl:ENSP00000482527|ensembl:ENSP00000483266|ensembl:ENSP00000483436|ensembl:ENSP00000484225|ensembl:ENSP00000484465|ensembl:ENSP00000484694|ensembl:ENSP00000484865|ensembl:ENSP00000484964	intact:EBI-11784425	psi-mi:sen34_human(display_long)|uniprotkb:TSEN34(gene name)|psi-mi:TSEN34(display_short)|uniprotkb:LENG5(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 5(gene name synonym)|uniprotkb:SEN34(gene name synonym)|uniprotkb:tRNA-intron endonuclease Sen34(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26428885|imex:IM-28428-92	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001070914.1|refseq:NP_001269261.1|refseq:NP_076980.2|refseq:XP_011525596.1|refseq:XP_011525597.1|ensembl:ENSG00000170892(gene)|ensembl:ENSG00000273896(gene)|ensembl:ENSG00000274078(gene)|ensembl:ENSG00000274129(gene)|ensembl:ENSG00000274672(gene)|ensembl:ENSG00000274796(gene)|ensembl:ENSG00000275165(gene)|ensembl:ENSG00000278605(gene)|ensembl:ENSG00000278622(gene)|ensembl:ENSG00000278712(gene)|ensembl:ENST00000302937(transcript)|ensembl:ENST00000396383(transcript)|ensembl:ENST00000396388(transcript)|ensembl:ENST00000429671(transcript)|ensembl:ENST00000455798(transcript)|ensembl:ENST00000611560(transcript)|ensembl:ENST00000611798(transcript)|ensembl:ENST00000612236(transcript)|ensembl:ENST00000612393(transcript)|ensembl:ENST00000613310(transcript)|ensembl:ENST00000613712(transcript)|ensembl:ENST00000613888(transcript)|ensembl:ENST00000614948(transcript)|ensembl:ENST00000614984(transcript)|ensembl:ENST00000615000(transcript)|ensembl:ENST00000615079(transcript)|ensembl:ENST00000615900(transcript)|ensembl:ENST00000615975(transcript)|ensembl:ENST00000616063(transcript)|ensembl:ENST00000616209(transcript)|ensembl:ENST00000617149(transcript)|ensembl:ENST00000617902(transcript)|ensembl:ENST00000618135(transcript)|ensembl:ENST00000619994(transcript)|ensembl:ENST00000622524(transcript)|ensembl:ENST00000622538(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0016829"(lyase activity)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR016690(tRNA-splicing endonuclease, SEN34 subunit)|interpro:IPR036167|rcsb pdb:6Z9U|reactome:R-HSA-6784531	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/10/26	rogid:4uEnLuOfSUb8jpuApGOMyuNgxCo9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:j+5oo6hX9ZjwuwVVHvaLLgUQ7a0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P01876	uniprotkb:O00602-PRO_0000009136	intact:EBI-727651|ensembl:ENSP00000374989|ensembl:ENSP00000488021	intact:EBI-11784425	psi-mi:igha1_human(display_long)|uniprotkb:IGHA1(gene name)|psi-mi:IGHA1(display_short)|uniprotkb:Ig alpha-1 chain C region(gene name synonym)|uniprotkb:Ig alpha-1 chain C region BUR(gene name synonym)|uniprotkb:Ig alpha-1 chain C region TRO(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26428889|imex:IM-28428-94	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000211895(gene)|ensembl:ENSG00000282633(gene)|ensembl:ENST00000390547(transcript)|ensembl:ENST00000633714(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:0071748"(monomeric IgA immunoglobulin complex)|go:"GO:0071751"(secretory IgA immunoglobulin complex)|go:"GO:0071752"(secretory dimeric IgA immunoglobulin complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1IGA|rcsb pdb:1OW0|rcsb pdb:2ESG|rcsb pdb:2QEJ|rcsb pdb:3CHN|rcsb pdb:6LX3|rcsb pdb:6LXW|rcsb pdb:6UE7|rcsb pdb:6XJA|reactome:R-HSA-202733|reactome:R-HSA-2168880|go:"GO:0070062"(extracellular exosome)	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/10/26	rogid:Mystbtg9uttxFXl//LGdoM32po09606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:BnmM3Ir1ipf3g7ev12siaFFXOqE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BXX0	uniprotkb:O00602-PRO_0000009136	intact:EBI-11740176|uniprotkb:B2RMY3|uniprotkb:Q8NBH3|uniprotkb:Q96JQ4|ensembl:ENSP00000254528	intact:EBI-11784425	psi-mi:emil2_human(display_long)|uniprotkb:EMILIN2(gene name)|psi-mi:EMILIN2(display_short)|uniprotkb:Elastin microfibril interface-located protein 2(gene name synonym)|uniprotkb:Protein FOAP-10(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357694|imex:IM-28428-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114437.2|ensembl:ENSG00000132205(gene)|ensembl:ENST00000254528(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0007155"(cell adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR011489(EMI)|reactome:R-HSA-2129379|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:YncpkDHFOyL1VjUqbv8fJS1EUAo9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:bjsju9bAEXSXiktC9KXhHHU8V3g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NPA2	uniprotkb:O00602-PRO_0000009136	intact:EBI-12346397|ensembl:ENSP00000337816|uniprotkb:D3DUA8|uniprotkb:Q9H3Q0	intact:EBI-11784425	psi-mi:mmp25_human(display_long)|uniprotkb:MMP25(gene name)|psi-mi:MMP25(display_short)|uniprotkb:Leukolysin(gene name synonym)|uniprotkb:MMP20(gene name synonym)|uniprotkb:MMPL1(gene name synonym)|uniprotkb:MT6MMP(gene name synonym)|uniprotkb:Membrane-type matrix metalloproteinase 6(gene name synonym)|uniprotkb:Membrane-type-6 matrix metalloproteinase(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357702|imex:IM-28428-89	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000008516(gene)|ensembl:ENST00000336577(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006954"(inflammatory response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0060022"(hard palate development)|interpro:IPR000585(Hemopexin)|interpro:IPR001818(Peptidase M10A and M12B, matrixin and adamalysin)|interpro:IPR002477(Peptidoglycan binding-like)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR018487|interpro:IPR021190|interpro:IPR024079|interpro:IPR033739|interpro:IPR036375|reactome:R-HSA-1592389|reactome:R-HSA-6798695|refseq:NP_071913.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Fig.2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:SE0WQPRMWbeDC9M8jirqfsT400E9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:hl9DFOONxInnbQW0UF6ZilbiCJk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15552	uniprotkb:O00602-PRO_0000009136	intact:EBI-2833872|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5|ensembl:ENSP00000246549|ensembl:ENSP00000473159	intact:EBI-11784425	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357713|imex:IM-28428-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|ensembl:ENSG00000126262(gene)|ensembl:ENST00000246549(transcript)|ensembl:ENST00000599180(transcript)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0002879"(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0090276"(regulation of peptide hormone secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Fig. 2 A/B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:4dhdSPbu2QfaF+AfCo91/6irf6Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P80217	uniprotkb:O00602-PRO_0000009136	intact:EBI-2115067|uniprotkb:Q92984|uniprotkb:Q99537|uniprotkb:Q9BV98|uniprotkb:C9JGX1|ensembl:ENSP00000394579	intact:EBI-11784425	psi-mi:in35_human(display_long)|uniprotkb:IFI35(gene name)|psi-mi:IFI35(display_short)|uniprotkb:IFP35(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357735|imex:IM-28428-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005524.2|refseq:NP_001317159.1|ensembl:ENSG00000068079(gene)|ensembl:ENST00000415816(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034460|mint:P80217|reactome:R-HSA-909733	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:IR0w7n2R0RaTZ9n8A3cWylc2Jd49606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:419nyyFn42XR4SPQyyJ96TL4yek	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15552	uniprotkb:O00602-PRO_0000009136	intact:EBI-2833872|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5|ensembl:ENSP00000246549|ensembl:ENSP00000473159	intact:EBI-11784425	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357895|imex:IM-28428-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|ensembl:ENSG00000126262(gene)|ensembl:ENST00000246549(transcript)|ensembl:ENST00000599180(transcript)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0002879"(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0090276"(regulation of peptide hormone secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Fig. 2E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:4dhdSPbu2QfaF+AfCo91/6irf6Y	false	-	sufficient binding region:80-297(IPR002181)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00602-PRO_0000009136	uniprotkb:O15552	intact:EBI-11784425	intact:EBI-2833872|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5|ensembl:ENSP00000246549|ensembl:ENSP00000473159	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26358529|imex:IM-28428-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5282479(chain-parent)	refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|ensembl:ENSG00000126262(gene)|ensembl:ENST00000246549(transcript)|ensembl:ENST00000599180(transcript)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0002879"(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0090276"(regulation of peptide hormone secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1	-	chain-seq-start:30|chain-seq-end:326	-	figure legend:Fig. 2E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	rigid:4dhdSPbu2QfaF+AfCo91/6irf6Y	false	-	sufficient binding region:180-330|sufficient binding region:1-180	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15485	uniprotkb:O15552	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-2833872|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5|ensembl:ENSP00000246549|ensembl:ENSP00000473159	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26358989|imex:IM-28428-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|ensembl:ENSG00000126262(gene)|ensembl:ENST00000246549(transcript)|ensembl:ENST00000599180(transcript)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0002879"(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0090276"(regulation of peptide hormone secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:Supp. Fig. 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	rigid:zkNMGUgg7O95ChEviee5VJJ0WTI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15552	uniprotkb:O00602-PRO_0000009136	intact:EBI-2833872|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5|ensembl:ENSP00000246549|ensembl:ENSP00000473159	intact:EBI-11784425	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26428896|imex:IM-28428-96	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|ensembl:ENSG00000126262(gene)|ensembl:ENST00000246549(transcript)|ensembl:ENST00000599180(transcript)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0002879"(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0090276"(regulation of peptide hormone secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Fig. 2B, Supp. Fig. 8|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/10/26	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:4dhdSPbu2QfaF+AfCo91/6irf6Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15552	uniprotkb:O00602-PRO_0000009136	intact:EBI-2833872|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5|ensembl:ENSP00000246549|ensembl:ENSP00000473159	intact:EBI-11784425	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357817|imex:IM-28428-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|ensembl:ENSG00000126262(gene)|ensembl:ENST00000246549(transcript)|ensembl:ENST00000599180(transcript)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0002879"(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0090276"(regulation of peptide hormone secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Fig. 2C, Supp.FIg. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/09/25	2020/09/25	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:4dhdSPbu2QfaF+AfCo91/6irf6Y	false	mcherry fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:O15552	uniprotkb:O00602-PRO_0000009136	intact:EBI-2833872|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5|ensembl:ENSP00000246549|ensembl:ENSP00000473159	intact:EBI-11784425	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26357847|imex:IM-28428-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|ensembl:ENSG00000126262(gene)|ensembl:ENST00000246549(transcript)|ensembl:ENST00000599180(transcript)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0002879"(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0090276"(regulation of peptide hormone secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Fig. 2D, Supp.FIg. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/09/25	2020/09/25	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:4dhdSPbu2QfaF+AfCo91/6irf6Y	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O15552	uniprotkb:O00602	intact:EBI-2833872|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5|ensembl:ENSP00000246549|ensembl:ENSP00000473159	intact:EBI-5282479|uniprotkb:Q5VYV5|uniprotkb:Q92596|ensembl:ENSP00000360871	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	psi-mi:fcn1_human(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26358561|imex:IM-28428-77	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|ensembl:ENSG00000126262(gene)|ensembl:ENST00000246549(transcript)|ensembl:ENST00000599180(transcript)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0002879"(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0090276"(regulation of peptide hormone secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1	refseq:NP_001994.2|ensembl:ENSG00000085265(gene)|ensembl:ENST00000371806(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033691"(sialic acid binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:O00602|rcsb pdb:2D39|rcsb pdb:2JHH|rcsb pdb:2JHI|rcsb pdb:2JHK|rcsb pdb:2JHL|rcsb pdb:2JHM|rcsb pdb:2WNP|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 2D, 5B, Supp.FIg. 1B|comment:Interaction was not pH dependent|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-monocyte)|taxid:9606(Human mononuclear cells)	-	2020/09/25	2020/09/25	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	rogid:7qu36ZaWgX+GyX+QUbGj0RGrp4U9606	rigid:vV3StQR9DOHE92+k2D5qGD5CiYA	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P02741	uniprotkb:O00602	intact:EBI-1395983|uniprotkb:A8K078|uniprotkb:Q08AK3|uniprotkb:Q8WW75|uniprotkb:D3DVD9|uniprotkb:D3DVE0|ensembl:ENSP00000255030	intact:EBI-5282479|uniprotkb:Q5VYV5|uniprotkb:Q92596|ensembl:ENSP00000360871	psi-mi:crp_human(display_long)|uniprotkb:CRP(gene name)|psi-mi:CRP(display_short)|uniprotkb:PTX1(gene name synonym)	psi-mi:fcn1_human(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26358880|imex:IM-28428-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000558.2|refseq:NP_001315986.1|refseq:NP_001315987.1|dip:DIP-39125N|ensembl:ENSG00000132693(gene)|ensembl:ENST00000255030(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008228"(opsonization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0033265"(choline binding)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|mint:P02741|rcsb pdb:1B09|rcsb pdb:1CRV|rcsb pdb:1GNH|rcsb pdb:1LJ7|rcsb pdb:3L2Y|rcsb pdb:3PVN|rcsb pdb:3PVO|reactome:R-HSA-173623	refseq:NP_001994.2|ensembl:ENSG00000085265(gene)|ensembl:ENST00000371806(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033691"(sialic acid binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:O00602|rcsb pdb:2D39|rcsb pdb:2JHH|rcsb pdb:2JHI|rcsb pdb:2JHK|rcsb pdb:2JHL|rcsb pdb:2JHM|rcsb pdb:2WNP|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-monocyte)|taxid:9606(Human mononuclear cells)	-	2020/09/25	2020/10/26	rogid:R7vKMSGKD4ETbUKVGL9IiL8jzjE9606	rogid:7qu36ZaWgX+GyX+QUbGj0RGrp4U9606	rigid:gbzewVp74A1N+13Nt//FvcTGfRg	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P02741	uniprotkb:O00602	intact:EBI-1395983|uniprotkb:A8K078|uniprotkb:Q08AK3|uniprotkb:Q8WW75|uniprotkb:D3DVD9|uniprotkb:D3DVE0|ensembl:ENSP00000255030	intact:EBI-5282479|uniprotkb:Q5VYV5|uniprotkb:Q92596|ensembl:ENSP00000360871	psi-mi:crp_human(display_long)|uniprotkb:CRP(gene name)|psi-mi:CRP(display_short)|uniprotkb:PTX1(gene name synonym)	psi-mi:fcn1_human(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26358852|imex:IM-28428-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000558.2|refseq:NP_001315986.1|refseq:NP_001315987.1|dip:DIP-39125N|ensembl:ENSG00000132693(gene)|ensembl:ENST00000255030(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008228"(opsonization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0033265"(choline binding)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|mint:P02741|rcsb pdb:1B09|rcsb pdb:1CRV|rcsb pdb:1GNH|rcsb pdb:1LJ7|rcsb pdb:3L2Y|rcsb pdb:3PVN|rcsb pdb:3PVO|reactome:R-HSA-173623	refseq:NP_001994.2|ensembl:ENSG00000085265(gene)|ensembl:ENST00000371806(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033691"(sialic acid binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:O00602|rcsb pdb:2D39|rcsb pdb:2JHH|rcsb pdb:2JHI|rcsb pdb:2JHK|rcsb pdb:2JHL|rcsb pdb:2JHM|rcsb pdb:2WNP|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 5A|comment:Binding is stronger at pH6.5 than 7.4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/09/25	rogid:R7vKMSGKD4ETbUKVGL9IiL8jzjE9606	rogid:7qu36ZaWgX+GyX+QUbGj0RGrp4U9606	rigid:gbzewVp74A1N+13Nt//FvcTGfRg	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O00602-PRO_0000009136	uniprotkb:P02769	intact:EBI-11784425	intact:EBI-2296927|uniprotkb:A5PJX3|uniprotkb:O02787|uniprotkb:P04277|uniprotkb:Q3SZR2	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:albu_bovin(display_long)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:BSA(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26428981|imex:IM-28428-100	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5282479(chain-parent)	rcsb pdb:4JK4|refseq:NP_851335.1|interpro:IPR000264(Serum albumin)|interpro:IPR020858|interpro:IPR020857|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR021177|rcsb pdb:2L7U|rcsb pdb:3V03|rcsb pdb:4F5S|rcsb pdb:4OR0|rcsb pdb:6QS9|rcsb pdb:6RJV|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:1903981"(enterobactin binding)	-	chain-seq-start:30|chain-seq-end:326	-	figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/10/26	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rogid:J8N23Xjyoe+UM5phxwqJtC2a1+M9913	rigid:+AEnVmHq+vmyYDfpWAh+uDZSkkY	false	sufficient binding region:81-297	mono N-acetylated residue:?-?	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O00602-PRO_0000009136	uniprotkb:P02741	intact:EBI-11784425	intact:EBI-1395983|uniprotkb:A8K078|uniprotkb:Q08AK3|uniprotkb:Q8WW75|uniprotkb:D3DVD9|uniprotkb:D3DVE0|ensembl:ENSP00000255030	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:crp_human(display_long)|uniprotkb:CRP(gene name)|psi-mi:CRP(display_short)|uniprotkb:PTX1(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26428991|imex:IM-28428-102	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5282479(chain-parent)	refseq:NP_000558.2|refseq:NP_001315986.1|refseq:NP_001315987.1|dip:DIP-39125N|ensembl:ENSG00000132693(gene)|ensembl:ENST00000255030(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008228"(opsonization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0033265"(choline binding)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|mint:P02741|rcsb pdb:1B09|rcsb pdb:1CRV|rcsb pdb:1GNH|rcsb pdb:1LJ7|rcsb pdb:3L2Y|rcsb pdb:3PVN|rcsb pdb:3PVO|reactome:R-HSA-173623	-	chain-seq-start:30|chain-seq-end:326	-	figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/10/26	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rogid:R7vKMSGKD4ETbUKVGL9IiL8jzjE9606	rigid:V/HrJEwaoeBJOEBtqyOXmKaj2sc	false	sufficient binding region:81-297	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:O00602-PRO_0000009136	uniprotkb:P02769	intact:EBI-11784425	intact:EBI-2296927|uniprotkb:A5PJX3|uniprotkb:O02787|uniprotkb:P04277|uniprotkb:Q3SZR2	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:albu_bovin(display_long)|uniprotkb:ALB(gene name)|psi-mi:ALB(display_short)|uniprotkb:BSA(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26428991|imex:IM-28428-102	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-5282479(chain-parent)	rcsb pdb:4JK4|refseq:NP_851335.1|interpro:IPR000264(Serum albumin)|interpro:IPR020858|interpro:IPR020857|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR021177|rcsb pdb:2L7U|rcsb pdb:3V03|rcsb pdb:4F5S|rcsb pdb:4OR0|rcsb pdb:6QS9|rcsb pdb:6RJV|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:1903981"(enterobactin binding)	-	chain-seq-start:30|chain-seq-end:326	-	figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/10/26	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rogid:J8N23Xjyoe+UM5phxwqJtC2a1+M9913	rigid:V/HrJEwaoeBJOEBtqyOXmKaj2sc	false	sufficient binding region:81-297	mono N-acetylated residue:?-?	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P02741	uniprotkb:O15552	intact:EBI-1395983|uniprotkb:A8K078|uniprotkb:Q08AK3|uniprotkb:Q8WW75|uniprotkb:D3DVD9|uniprotkb:D3DVE0|ensembl:ENSP00000255030	intact:EBI-2833872|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5|ensembl:ENSP00000246549|ensembl:ENSP00000473159	psi-mi:crp_human(display_long)|uniprotkb:CRP(gene name)|psi-mi:CRP(display_short)|uniprotkb:PTX1(gene name synonym)	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	psi-mi:"MI:0588"(three hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26358944|imex:IM-28428-91	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000558.2|refseq:NP_001315986.1|refseq:NP_001315987.1|dip:DIP-39125N|ensembl:ENSG00000132693(gene)|ensembl:ENST00000255030(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008228"(opsonization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0033265"(choline binding)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|mint:P02741|rcsb pdb:1B09|rcsb pdb:1CRV|rcsb pdb:1GNH|rcsb pdb:1LJ7|rcsb pdb:3L2Y|rcsb pdb:3PVN|rcsb pdb:3PVO|reactome:R-HSA-173623	refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|ensembl:ENSG00000126262(gene)|ensembl:ENST00000246549(transcript)|ensembl:ENST00000599180(transcript)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0002879"(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0090276"(regulation of peptide hormone secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1	-	-	-	figure legend:Supp.Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:R7vKMSGKD4ETbUKVGL9IiL8jzjE9606	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	rigid:8hDz9sz9U8uh52rr+lQpLUQIHwc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02741	uniprotkb:O00602-PRO_0000009136	intact:EBI-1395983|uniprotkb:A8K078|uniprotkb:Q08AK3|uniprotkb:Q8WW75|uniprotkb:D3DVD9|uniprotkb:D3DVE0|ensembl:ENSP00000255030	intact:EBI-11784425	psi-mi:crp_human(display_long)|uniprotkb:CRP(gene name)|psi-mi:CRP(display_short)|uniprotkb:PTX1(gene name synonym)	psi-mi:o00602-pro_0000009136(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0588"(three hybrid)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26358944|imex:IM-28428-91	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000558.2|refseq:NP_001315986.1|refseq:NP_001315987.1|dip:DIP-39125N|ensembl:ENSG00000132693(gene)|ensembl:ENST00000255030(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008228"(opsonization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0033265"(choline binding)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|mint:P02741|rcsb pdb:1B09|rcsb pdb:1CRV|rcsb pdb:1GNH|rcsb pdb:1LJ7|rcsb pdb:3L2Y|rcsb pdb:3PVN|rcsb pdb:3PVO|reactome:R-HSA-173623	intact:EBI-5282479(chain-parent)	-	-	chain-seq-start:30|chain-seq-end:326	figure legend:Supp.Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/09/25	2020/09/25	rogid:R7vKMSGKD4ETbUKVGL9IiL8jzjE9606	rogid:lTaQw2TU6drH0Rwv4iOyx5zQXZo9606	rigid:8hDz9sz9U8uh52rr+lQpLUQIHwc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02741	uniprotkb:O00602	intact:EBI-1395983|uniprotkb:A8K078|uniprotkb:Q08AK3|uniprotkb:Q8WW75|uniprotkb:D3DVD9|uniprotkb:D3DVE0|ensembl:ENSP00000255030	intact:EBI-5282479|uniprotkb:Q5VYV5|uniprotkb:Q92596|ensembl:ENSP00000360871	psi-mi:crp_human(display_long)|uniprotkb:CRP(gene name)|psi-mi:CRP(display_short)|uniprotkb:PTX1(gene name synonym)	psi-mi:fcn1_human(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0944"(mass spectrometry study of hydrogen/deuterium exchange)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26358965|imex:IM-28428-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000558.2|refseq:NP_001315986.1|refseq:NP_001315987.1|dip:DIP-39125N|ensembl:ENSG00000132693(gene)|ensembl:ENST00000255030(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008228"(opsonization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0033265"(choline binding)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|mint:P02741|rcsb pdb:1B09|rcsb pdb:1CRV|rcsb pdb:1GNH|rcsb pdb:1LJ7|rcsb pdb:3L2Y|rcsb pdb:3PVN|rcsb pdb:3PVO|reactome:R-HSA-173623	refseq:NP_001994.2|ensembl:ENSG00000085265(gene)|ensembl:ENST00000371806(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033691"(sialic acid binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:O00602|rcsb pdb:2D39|rcsb pdb:2JHH|rcsb pdb:2JHI|rcsb pdb:2JHK|rcsb pdb:2JHL|rcsb pdb:2JHM|rcsb pdb:2WNP|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|reactome:R-HSA-6798695	-	-	-	figure legend:Supp. Fig.  6|comment:Binding is stronger at pH6.5 than 7.4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/09/25	rogid:R7vKMSGKD4ETbUKVGL9IiL8jzjE9606	rogid:7qu36ZaWgX+GyX+QUbGj0RGrp4U9606	rigid:gbzewVp74A1N+13Nt//FvcTGfRg	false	sufficient binding region:71-82|sufficient binding region:53-64	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02741	uniprotkb:O00602	intact:EBI-1395983|uniprotkb:A8K078|uniprotkb:Q08AK3|uniprotkb:Q8WW75|uniprotkb:D3DVD9|uniprotkb:D3DVE0|ensembl:ENSP00000255030	intact:EBI-5282479|uniprotkb:Q5VYV5|uniprotkb:Q92596|ensembl:ENSP00000360871	psi-mi:crp_human(display_long)|uniprotkb:CRP(gene name)|psi-mi:CRP(display_short)|uniprotkb:PTX1(gene name synonym)	psi-mi:fcn1_human(display_long)|uniprotkb:FCN1(gene name)|psi-mi:FCN1(display_short)|uniprotkb:FCNM(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 1(gene name synonym)|uniprotkb:Ficolin-A(gene name synonym)|uniprotkb:Ficolin-alpha(gene name synonym)|uniprotkb:M-ficolin(gene name synonym)	psi-mi:"MI:0944"(mass spectrometry study of hydrogen/deuterium exchange)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26358975|imex:IM-28428-79	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000558.2|refseq:NP_001315986.1|refseq:NP_001315987.1|dip:DIP-39125N|ensembl:ENSG00000132693(gene)|ensembl:ENST00000255030(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008228"(opsonization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0033265"(choline binding)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|mint:P02741|rcsb pdb:1B09|rcsb pdb:1CRV|rcsb pdb:1GNH|rcsb pdb:1LJ7|rcsb pdb:3L2Y|rcsb pdb:3PVN|rcsb pdb:3PVO|reactome:R-HSA-173623	refseq:NP_001994.2|ensembl:ENSG00000085265(gene)|ensembl:ENST00000371806(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033691"(sialic acid binding)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:O00602|rcsb pdb:2D39|rcsb pdb:2JHH|rcsb pdb:2JHI|rcsb pdb:2JHK|rcsb pdb:2JHL|rcsb pdb:2JHM|rcsb pdb:2WNP|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086|reactome:R-HSA-6798695	-	-	-	figure legend:Supp. Fig. 5|comment:Binding is stronger at pH6.5 than 7.4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/09/25	rogid:R7vKMSGKD4ETbUKVGL9IiL8jzjE9606	rogid:7qu36ZaWgX+GyX+QUbGj0RGrp4U9606	rigid:gbzewVp74A1N+13Nt//FvcTGfRg	false	-	sufficient binding region:205-220	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02741	uniprotkb:O15552	intact:EBI-1395983|uniprotkb:A8K078|uniprotkb:Q08AK3|uniprotkb:Q8WW75|uniprotkb:D3DVD9|uniprotkb:D3DVE0|ensembl:ENSP00000255030	intact:EBI-2833872|uniprotkb:Q4VBL5|uniprotkb:B0M0J9|uniprotkb:Q4VAZ3|uniprotkb:Q4VAZ5|ensembl:ENSP00000246549|ensembl:ENSP00000473159	psi-mi:crp_human(display_long)|uniprotkb:CRP(gene name)|psi-mi:CRP(display_short)|uniprotkb:PTX1(gene name synonym)	psi-mi:ffar2_human(display_long)|uniprotkb:FFAR2(gene name)|psi-mi:FFAR2(display_short)|uniprotkb:GPR43(gene name synonym)|uniprotkb:G-protein coupled receptor 43(gene name synonym)|uniprotkb:FFA2(gene name synonym)|uniprotkb:GPCR43(gene name synonym)	psi-mi:"MI:0813"(proximity ligation assay)	Zhang et al. (2010)	pubmed:21037097|imex:IM-28428	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26428945|imex:IM-28428-98	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000558.2|refseq:NP_001315986.1|refseq:NP_001315987.1|dip:DIP-39125N|ensembl:ENSG00000132693(gene)|ensembl:ENST00000255030(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008228"(opsonization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0033265"(choline binding)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|mint:P02741|rcsb pdb:1B09|rcsb pdb:1CRV|rcsb pdb:1GNH|rcsb pdb:1LJ7|rcsb pdb:3L2Y|rcsb pdb:3PVN|rcsb pdb:3PVO|reactome:R-HSA-173623	refseq:XP_016882198.1|refseq:XP_016882199.1|refseq:XP_016882200.1|ensembl:ENSG00000126262(gene)|ensembl:ENST00000246549(transcript)|ensembl:ENST00000599180(transcript)|go:"GO:0002232"(leukocyte chemotaxis involved in inflammatory response)|go:"GO:0002385"(mucosal immune response)|go:"GO:0002673"(regulation of acute inflammatory response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002752"(cell surface pattern recognition receptor signaling pathway)|go:"GO:0002879"(positive regulation of acute inflammatory response to non-antigenic stimulus)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042995"(cell projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0090276"(regulation of peptide hormone secretion)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR013312(GPR40-related receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-416476|reactome:R-HSA-444209|refseq:NP_005297.1	-	-	-	figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-monocyte)|taxid:9606(Human mononuclear cells)	-	2020/09/25	2020/10/26	rogid:R7vKMSGKD4ETbUKVGL9IiL8jzjE9606	rogid:bebhdJ83A+Tv06Z18DScIZKjUuM9606	rigid:giCRngrLnVnYhNnhNg6CdQjDu1c	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)