#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P40692	uniprotkb:P54278	intact:EBI-744248|uniprotkb:B4DI13|uniprotkb:B4DQ11|uniprotkb:E9PCU2|ensembl:ENSP00000231790	intact:EBI-1162561|uniprotkb:Q5FBW9|uniprotkb:Q5FBX1|uniprotkb:Q5FBX2|uniprotkb:Q52LH6|uniprotkb:Q75MR2|uniprotkb:B2R610|ensembl:ENSP00000265849	psi-mi:mlh1_human(display_long)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:COCA2(gene name synonym)	psi-mi:pms2_human(display_long)|uniprotkb:PMS1 protein homolog 2(gene name synonym)|uniprotkb:DNA mismatch repair protein PMS2(gene name synonym)|uniprotkb:PMS2(gene name)|psi-mi:PMS2(display_short)|uniprotkb:PMSL2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kosinski et al. (2010)	pubmed:20533529|imex:IM-27693	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25421867|imex:IM-27693-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000240.1|refseq:NP_001161089.1|refseq:NP_001161090.1|refseq:NP_001161091.1|refseq:NP_001245200.1|refseq:NP_001245202.1|refseq:NP_001245203.1|dip:DIP-27601N|refseq:XP_005265220.1|refseq:XP_005265221.1|ensembl:ENSG00000076242(gene)|ensembl:ENST00000231790(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005712"(chiasma)|go:"GO:0005715"(late recombination nodule)|go:"GO:0006298"(mismatch repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007060"(male meiosis chromosome segregation)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0019899"(enzyme binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0043060"(meiotic metaphase I plate congression)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0045190"(isotype switching)|go:"GO:0045950"(negative regulation of mitotic recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048477"(oogenesis)|go:"GO:0051257"(meiotic spindle midzone assembly)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|mint:P40692|rcsb pdb:3RBN|rcsb pdb:4P7A|rcsb pdb:5U5P|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|reactome:R-HSA-912446	ensembl:ENSG00000122512(gene)|ensembl:ENST00000265849(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006298"(mismatch repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0032138"(single base insertion or deletion binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|mint:P54278|rcsb pdb:1H7S|rcsb pdb:1H7U|rcsb pdb:5U5R|rcsb pdb:6MFQ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5545483|reactome:R-HSA-5632987|reactome:R-HSA-6796648|rcsb pdb:1EA6|refseq:NP_000526.2|refseq:NP_001308932.1|refseq:NP_001308933.1|refseq:NP_001308934.1|refseq:NP_001308935.1|refseq:NP_001308936.1|refseq:NP_001308937.1|refseq:NP_001308938.1|refseq:NP_001308939.1|refseq:NP_001308940.1|refseq:NP_001308941.1|refseq:NP_001308942.1|refseq:NP_001308943.1|refseq:NP_001308944.1|refseq:XP_016885888.1|dip:DIP-46295N	-	-	-	figure legend:Figure 3|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/02/03	2020/02/03	rogid:v/ydpM1Cf5bF27dC+3JF6XXMp0Q9606	rogid:ZEPZOzJgtNSaYyRonkvr/+/30AE9606	rigid:V+h9QsGaEB7a1kNJz2tPPj4Yzzw	false	mutation decreasing interaction strength:542-542(rs63750511)|mutation decreasing interaction strength:622-622(rs63750693)|mutation decreasing interaction strength:636-636(rs63750825)|mutation increasing interaction strength:659-659(rs63749900)|mutation decreasing interaction strength:662-662(rs587778964)|mutation with no effect:663-663|mutation decreasing interaction strength:749-749(rs267607894)|mutation decreasing interaction strength:750-756(rs267607893)|mutation decreasing interaction strength:551-551(rs63750271)|mutation decreasing interaction strength:559-559(rs63750059)|mutation decreasing interaction strength:586-586(rs63751176)|mutation increasing interaction strength:601-601(rs63750718)|mutation increasing interaction strength:618-618(rs63750449)|mutation decreasing interaction strength:648-648(rs63750610)|mutation decreasing interaction strength:654-654(rs63750726)|mutation decreasing interaction strength:659-659(rs63749900)|mutation increasing interaction strength:755-755|mutation decreasing interaction strength:755-755	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)