#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P41227 uniprotkb:Q6N069 intact:EBI-747693|uniprotkb:A6NM98|ensembl:ENSP00000417763 intact:EBI-2561139|ensembl:ENSP00000368716|uniprotkb:Q5VSP9|uniprotkb:Q8N5J3|uniprotkb:Q6P2D5|uniprotkb:Q8N870|uniprotkb:B0QZ59 psi-mi:naa10_human(display_long)|uniprotkb:ARD1(gene name synonym)|uniprotkb:NAA10(gene name)|psi-mi:NAA10(display_short)|uniprotkb:TE2(gene name synonym)|uniprotkb:NatA catalytic subunit Naa10(gene name synonym)|uniprotkb:ARD1A(gene name synonym)|uniprotkb:N-terminal acetyltransferase complex ARD1 subunit homolog A(gene name synonym) psi-mi:naa16_human(display_long)|uniprotkb:NARG1L(gene name synonym)|uniprotkb:NMDA receptor-regulated 1-like protein(gene name synonym)|uniprotkb:NAT2(gene name synonym)|uniprotkb:NAA16(gene name)|psi-mi:NAA16(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Arnesen et al. (2009) imex:IM-28453|pubmed:19480662 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26376295|imex:IM-28453-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243048.1|refseq:NP_003482.1|ensembl:ENST00000464845(transcript)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006323"(DNA packaging)|go:"GO:0006473"(protein acetylation)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0017198"(N-terminal peptidyl-serine acetylation)|go:"GO:0018002"(N-terminal peptidyl-glutamic acid acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:1990189"(peptide-serine-N-acetyltransferase activity)|go:"GO:1990190"(peptide-glutamate-N-acetyltransferase activity)|go:"GO:2000719"(negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR000182(GCN5-related N-acetyltransferase)|ensembl:ENSG00000102030(gene)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|mint:P41227|rcsb pdb:6C95|rcsb pdb:6C9M|rcsb pdb:6PPL|rcsb pdb:6PW9 ensembl:ENSG00000172766(gene)|ensembl:ENST00000379406(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR021183|mint:Q6N069|refseq:NP_001104268.1|refseq:NP_060997.2|refseq:NP_078837.3|refseq:XP_011533530.1 - - - figure legend:Figs.1 and 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/10/20 2020/10/20 rogid:h9fpQmX5wai9LCuW0bgwlDJQ8R49606 rogid:y23dxDxweBtEeb8mEsJ4bgD6N+Q9606 rigid:VkNUiqlmcBnsmhu1k2GJHMst8e4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41227 uniprotkb:Q9GZZ1 intact:EBI-747693|uniprotkb:A6NM98|ensembl:ENSP00000417763 intact:EBI-1052523|uniprotkb:Q68DQ1|uniprotkb:D3DN74|ensembl:ENSP00000240922 psi-mi:naa10_human(display_long)|uniprotkb:ARD1(gene name synonym)|uniprotkb:NAA10(gene name)|psi-mi:NAA10(display_short)|uniprotkb:TE2(gene name synonym)|uniprotkb:NatA catalytic subunit Naa10(gene name synonym)|uniprotkb:ARD1A(gene name synonym)|uniprotkb:N-terminal acetyltransferase complex ARD1 subunit homolog A(gene name synonym) psi-mi:naa50_human(display_long)|uniprotkb:NAA50(gene name)|psi-mi:NAA50(display_short)|uniprotkb:MAK3(gene name synonym)|uniprotkb:NAT5(gene name synonym)|uniprotkb:N-acetyltransferase 5(gene name synonym)|uniprotkb:N-acetyltransferase san homolog(gene name synonym)|uniprotkb:NAT13(gene name synonym)|uniprotkb:N-acetyltransferase 13(gene name synonym)|uniprotkb:NatE catalytic subunit(gene name synonym)|uniprotkb:N-epsilon-acetyltransferase 50(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Arnesen et al. (2009) imex:IM-28453|pubmed:19480662 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26376295|imex:IM-28453-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243048.1|refseq:NP_003482.1|ensembl:ENST00000464845(transcript)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006323"(DNA packaging)|go:"GO:0006473"(protein acetylation)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0017198"(N-terminal peptidyl-serine acetylation)|go:"GO:0018002"(N-terminal peptidyl-glutamic acid acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:1990189"(peptide-serine-N-acetyltransferase activity)|go:"GO:1990190"(peptide-glutamate-N-acetyltransferase activity)|go:"GO:2000719"(negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR000182(GCN5-related N-acetyltransferase)|ensembl:ENSG00000102030(gene)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|mint:P41227|rcsb pdb:6C95|rcsb pdb:6C9M|rcsb pdb:6PPL|rcsb pdb:6PW9 refseq:NP_079422.1|ensembl:ENSG00000121579(gene)|ensembl:ENST00000240922(transcript)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0052858"(peptidyl-lysine acetyltransferase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071962"(mitotic sister chromatid cohesion, centromeric)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|rcsb pdb:2OB0|rcsb pdb:2PSW|rcsb pdb:3TFY|rcsb pdb:4X5K|rcsb pdb:6PPL|rcsb pdb:6PW9|rcsb pdb:6WF3|rcsb pdb:6WF5|rcsb pdb:6WFG|rcsb pdb:6WFK|rcsb pdb:6WFN|rcsb pdb:6WFO - - - figure legend:Figs.1 and 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/10/20 2020/10/20 rogid:h9fpQmX5wai9LCuW0bgwlDJQ8R49606 rogid:jIExs5jdLry06sj1v4AhEd+RdHo9606 rigid:VkNUiqlmcBnsmhu1k2GJHMst8e4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41227 uniprotkb:Q9BXJ9 intact:EBI-747693|uniprotkb:A6NM98|ensembl:ENSP00000417763 intact:EBI-1042540|uniprotkb:Q52LG9|uniprotkb:Q8IWH4|uniprotkb:Q8NEV2|uniprotkb:Q9H8P6|uniprotkb:D3DNY6|ensembl:ENSP00000296543 psi-mi:naa10_human(display_long)|uniprotkb:ARD1(gene name synonym)|uniprotkb:NAA10(gene name)|psi-mi:NAA10(display_short)|uniprotkb:TE2(gene name synonym)|uniprotkb:NatA catalytic subunit Naa10(gene name synonym)|uniprotkb:ARD1A(gene name synonym)|uniprotkb:N-terminal acetyltransferase complex ARD1 subunit homolog A(gene name synonym) psi-mi:naa15_human(display_long)|uniprotkb:NAA15(gene name)|psi-mi:NAA15(display_short)|uniprotkb:GA19(gene name synonym)|uniprotkb:NATH(gene name synonym)|uniprotkb:TBDN100(gene name synonym)|uniprotkb:Gastric cancer antigen Ga19(gene name synonym)|uniprotkb:N-terminal acetyltransferase(gene name synonym)|uniprotkb:Protein tubedown-1(gene name synonym)|uniprotkb:Tbdn100(gene name synonym)|uniprotkb:NARG1(gene name synonym)|uniprotkb:NMDA receptor-regulated protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Arnesen et al. (2009) imex:IM-28453|pubmed:19480662 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26376295|imex:IM-28453-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243048.1|refseq:NP_003482.1|ensembl:ENST00000464845(transcript)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006323"(DNA packaging)|go:"GO:0006473"(protein acetylation)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0017198"(N-terminal peptidyl-serine acetylation)|go:"GO:0018002"(N-terminal peptidyl-glutamic acid acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:1990189"(peptide-serine-N-acetyltransferase activity)|go:"GO:1990190"(peptide-glutamate-N-acetyltransferase activity)|go:"GO:2000719"(negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR000182(GCN5-related N-acetyltransferase)|ensembl:ENSG00000102030(gene)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|mint:P41227|rcsb pdb:6C95|rcsb pdb:6C9M|rcsb pdb:6PPL|rcsb pdb:6PW9 refseq:NP_476516.1|go:"GO:0016604"(nuclear body)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR021183|mint:Q9BXJ9|rcsb pdb:6C95|rcsb pdb:6C9M|rcsb pdb:6PPL|rcsb pdb:6PW9|ensembl:ENSG00000164134(gene)|ensembl:ENST00000296543(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016020"(membrane) - - - figure legend:Figs.1 and 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/10/20 2020/10/20 rogid:h9fpQmX5wai9LCuW0bgwlDJQ8R49606 rogid:BGW5jQRBYXuf75thzj6cWvL2A5Y9606 rigid:VkNUiqlmcBnsmhu1k2GJHMst8e4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6N069 uniprotkb:P41227 intact:EBI-2561139|ensembl:ENSP00000368716|uniprotkb:Q5VSP9|uniprotkb:Q8N5J3|uniprotkb:Q6P2D5|uniprotkb:Q8N870|uniprotkb:B0QZ59 intact:EBI-747693|uniprotkb:A6NM98|ensembl:ENSP00000417763 psi-mi:naa16_human(display_long)|uniprotkb:NARG1L(gene name synonym)|uniprotkb:NMDA receptor-regulated 1-like protein(gene name synonym)|uniprotkb:NAT2(gene name synonym)|uniprotkb:NAA16(gene name)|psi-mi:NAA16(display_short) psi-mi:naa10_human(display_long)|uniprotkb:ARD1(gene name synonym)|uniprotkb:NAA10(gene name)|psi-mi:NAA10(display_short)|uniprotkb:TE2(gene name synonym)|uniprotkb:NatA catalytic subunit Naa10(gene name synonym)|uniprotkb:ARD1A(gene name synonym)|uniprotkb:N-terminal acetyltransferase complex ARD1 subunit homolog A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Arnesen et al. (2009) imex:IM-28453|pubmed:19480662 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26376307|imex:IM-28453-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172766(gene)|ensembl:ENST00000379406(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR021183|mint:Q6N069|refseq:NP_001104268.1|refseq:NP_060997.2|refseq:NP_078837.3|refseq:XP_011533530.1 refseq:NP_001243048.1|refseq:NP_003482.1|ensembl:ENST00000464845(transcript)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006323"(DNA packaging)|go:"GO:0006473"(protein acetylation)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0017198"(N-terminal peptidyl-serine acetylation)|go:"GO:0018002"(N-terminal peptidyl-glutamic acid acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:1990189"(peptide-serine-N-acetyltransferase activity)|go:"GO:1990190"(peptide-glutamate-N-acetyltransferase activity)|go:"GO:2000719"(negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR000182(GCN5-related N-acetyltransferase)|ensembl:ENSG00000102030(gene)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|mint:P41227|rcsb pdb:6C95|rcsb pdb:6C9M|rcsb pdb:6PPL|rcsb pdb:6PW9 - - - figure legend:Fig. 4A. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/10/20 2020/10/20 rogid:y23dxDxweBtEeb8mEsJ4bgD6N+Q9606 rogid:h9fpQmX5wai9LCuW0bgwlDJQ8R49606 rigid:V743jjozlDHIyChBKG/RLLJZl44 false flag tag:c-c|myc tag:c-c v5 tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6N069 uniprotkb:Q9BSU3 intact:EBI-2561139|ensembl:ENSP00000368716|uniprotkb:Q5VSP9|uniprotkb:Q8N5J3|uniprotkb:Q6P2D5|uniprotkb:Q8N870|uniprotkb:B0QZ59 intact:EBI-2585120|uniprotkb:Q66K19|uniprotkb:Q6P479|ensembl:ENSP00000286794 psi-mi:naa16_human(display_long)|uniprotkb:NARG1L(gene name synonym)|uniprotkb:NMDA receptor-regulated 1-like protein(gene name synonym)|uniprotkb:NAT2(gene name synonym)|uniprotkb:NAA16(gene name)|psi-mi:NAA16(display_short) psi-mi:naa11_human(display_long)|uniprotkb:NatA catalytic subunit Naa11(gene name synonym)|uniprotkb:ARD1B(gene name synonym)|uniprotkb:N-terminal acetyltransferase complex ARD1 subunit homolog B(gene name synonym)|uniprotkb:ARD2(gene name synonym)|uniprotkb:NAA11(gene name)|psi-mi:NAA11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Arnesen et al. (2009) imex:IM-28453|pubmed:19480662 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26376317|imex:IM-28453-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000172766(gene)|ensembl:ENST00000379406(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR021183|mint:Q6N069|refseq:NP_001104268.1|refseq:NP_060997.2|refseq:NP_078837.3|refseq:XP_011533530.1 refseq:NP_116082.1|ensembl:ENSG00000156269(gene)|ensembl:ENST00000286794(transcript)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017198"(N-terminal peptidyl-serine acetylation)|go:"GO:0018002"(N-terminal peptidyl-glutamic acid acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:1990189"(peptide-serine-N-acetyltransferase activity)|go:"GO:1990190"(peptide-glutamate-N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|refseq:XP_016864266.1|refseq:XP_016864267.1|refseq:XP_016864268.1 - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/10/20 2020/10/20 rogid:y23dxDxweBtEeb8mEsJ4bgD6N+Q9606 rogid:6hg8251LBnrp7AAra7KRLAKOJZ49606 rigid:TFRWP4z+lnkRFPBDVx5CQjcPcsk false flag tag:c-c|myc tag:c-c v5 tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intenz:2.3.1.255 intact:EBI-26429510 intact:EBI-26376332|rhea:"RHEA:50496"|rhea:"RHEA:50500"|rhea:"RHEA:50504"|rhea:"RHEA:50508"|rhea:"RHEA:50512"|rhea:"RHEA:50516" - psi-mi:naa10-naa16_human(display_short)|psi-mi:2.3.1.255(display_long)|intact:NatA N-alpha-acetyltransferase complex, NAA10-NAA16 variant(complex recommended name)|intact:"NAA10:NAA16"(complex systematic name)|intact:NAT2-ARD1 complex(complex synonym) psi-mi:sess(display_short)|psi-mi:EBI-26429510(display_long) psi-mi:"MI:0889"(acetylase assay) Arnesen et al. (2009) imex:IM-28453|pubmed:19480662 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0192"(acetylation reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-26429505|imex:IM-28453-7 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:1302"(stable complex) psi-mi:"MI:0327"(peptide) efo:"Orphanet:276432"(see-also)|efo:"Orphanet:568"(see-also)|intact:EBI-26376307(exp-evidence)|evidence ontology:"ECO:0000353"|go:"GO:0031415"(NatA complex)|pubmed:19480662(see-also)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0005737"(cytoplasm)|pubmed:30054468(see-also)|complex portal:CPX-6272(complex-primary) - go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity) curated-complex:"N(alpha)-acetyltransferases responsible for the covalent attachment of an acetyl group (CH3CO) to the free alpha-amino group (NH3+) at the N-terminal end of a polypeptide, one of the most common co-translational modifications. This changes the electrostatic properties of proteins and therefore protein function, stability and localization. NatA co-translationally acetylates N-termini that bear a small amino acid (Ala, Ser, Thr, Cys, and occasionally Val and Gly), which is exposed after methionine cleavage by methionine aminopeptidases."|disease:"Premature aging appearance-developmental delay-cardiac arrhythmia syndrome / N-terminal acetyltransferase deficiency (NATD) [Orphanet:276432] An enzymatic deficiency resulting in postnatal growth failure with severe delays and dysmorphic features. It is clinically characterized by wrinkled forehead, prominent eyes, widely opened anterior and posterior fontanels, downsloping palpebral fissures, thickened lids, large ears, flared nares, hypoplastic alae, short columella, protruding upper lip, and microretrognathia. There are also delayed closing of fontanels and broad great toes. Skin is characterized by redundancy or laxity with minimal subcutaneous fat, cutaneous capillary malformations, and very fine hair and eyebrows. Death results from cardiogenic shock following arrhythmia."|disease:"Microphthalmia, syndromic, 1 (MCOPS1) / Lenz type [Orphanet:568] A rare syndrome defined by the canonical features of unilateral or bilateral microphthalmia or anophthalmia and defects in the skeletal and genitourinary systems. Microphthalmia is a disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. Anomalies of the digits, teeth, and ears are hallmarks of MCOPS1. Intellectual disability ranges from mild to severe, with self-mutilating behaviors and seizures in severely affected MCOPS1 individuals." - figure legend:Fig. 8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/10/20 2020/10/27 - rogid:iSekbeGNeIFX0OH3QN5WrECx9qc-2 - false flag tag:?-? tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation)