#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P59595 uniprotkb:Q9HC16 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-717839|uniprotkb:Q45F02|uniprotkb:Q5TF77|uniprotkb:Q7Z2N1|uniprotkb:Q7Z2N4|uniprotkb:Q9H9H8|uniprotkb:B2RDR9|ensembl:ENSP00000385057 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:abc3g_human(display_long)|uniprotkb:APOBEC-related cytidine deaminase(gene name synonym)|uniprotkb:APOBEC-related protein 9(gene name synonym)|uniprotkb:CEM-15(gene name synonym)|uniprotkb:APOBEC3G(gene name)|psi-mi:APOBEC3G(display_short)|uniprotkb:Deoxycytidine deaminase(gene name synonym)|uniprotkb:MDS019(orf name) psi-mi:"MI:0096"(pull down) Wang et al. (2009) imex:IM-28118|pubmed:19345973 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25641899|imex:IM-28118-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_068594.1|ensembl:ENSG00000239713(gene)|ensembl:ENST00000407997(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008829"(dCTP deaminase activity)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030895"(apolipoprotein B mRNA editing enzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR040551|rcsb pdb:2KBO|rcsb pdb:2KEM|rcsb pdb:3E1U|rcsb pdb:3IQS|rcsb pdb:3IR2|rcsb pdb:3V4J|rcsb pdb:3V4K|rcsb pdb:4ROV|rcsb pdb:4ROW|rcsb pdb:5ZVA|rcsb pdb:5ZVB|rcsb pdb:6BUX|rcsb pdb:6BWY|rcsb pdb:6K3J|rcsb pdb:6K3K|reactome:R-HSA-180585|reactome:R-HSA-180689|rcsb pdb:2JYW|dip:DIP-37519N - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Fig 3|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/10 2020/06/10 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:o6JWyu1Is1J9e0CiLKAudHeFC4Y9606 rigid:1+kY8LGNN11e/TkahtQ8glmZqYM false glutathione s tranferase tag:n-n|sufficient binding region:2-168|sufficient binding region:302-421 ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P15130 uniprotkb:Q9HC16 intact:EBI-8172439|uniprotkb:Q66175|intact:MINT-8401910 intact:EBI-717839|uniprotkb:Q45F02|uniprotkb:Q5TF77|uniprotkb:Q7Z2N1|uniprotkb:Q7Z2N4|uniprotkb:Q9H9H8|uniprotkb:B2RDR9|ensembl:ENSP00000385057 psi-mi:ncap_cvh22(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:7(orf name) psi-mi:abc3g_human(display_long)|uniprotkb:APOBEC-related cytidine deaminase(gene name synonym)|uniprotkb:APOBEC-related protein 9(gene name synonym)|uniprotkb:CEM-15(gene name synonym)|uniprotkb:APOBEC3G(gene name)|psi-mi:APOBEC3G(display_short)|uniprotkb:Deoxycytidine deaminase(gene name synonym)|uniprotkb:MDS019(orf name) psi-mi:"MI:0096"(pull down) Wang et al. (2009) imex:IM-28118|pubmed:19345973 taxid:11137(hcov-229e)|taxid:11137(Human coronavirus 229E) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25641911|imex:IM-28118-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR042548|refseq:NP_073556.1|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|interpro:IPR037179|interpro:IPR037195|go:"GO:0003723"(RNA binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus) refseq:NP_068594.1|ensembl:ENSG00000239713(gene)|ensembl:ENST00000407997(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008829"(dCTP deaminase activity)|go:"GO:0009972"(cytidine deamination)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030895"(apolipoprotein B mRNA editing enzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR040551|rcsb pdb:2KBO|rcsb pdb:2KEM|rcsb pdb:3E1U|rcsb pdb:3IQS|rcsb pdb:3IR2|rcsb pdb:3V4J|rcsb pdb:3V4K|rcsb pdb:4ROV|rcsb pdb:4ROW|rcsb pdb:5ZVA|rcsb pdb:5ZVB|rcsb pdb:6BUX|rcsb pdb:6BWY|rcsb pdb:6K3J|rcsb pdb:6K3K|reactome:R-HSA-180585|reactome:R-HSA-180689|rcsb pdb:2JYW|dip:DIP-37519N - comment:mint|comment:homomint - figure legend:Fig 7|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/10 2020/06/10 rogid:xMioWN/dqCu8Qdp5Fg8thCKmchc11137 rogid:o6JWyu1Is1J9e0CiLKAudHeFC4Y9606 rigid:p/wWSIyA0KfOd3scSqtewWsWdHc false sufficient binding region:2-200|glutathione s tranferase tag:n-n|sufficient binding region:183-389 ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot)