#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q86SE9	uniprotkb:Q2GHU2	intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492	intact:EBI-26585631|ensemblbacteria:ABD44708	psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26585629|imex:IM-28642-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	-	-	-	figure legend:fig.2 table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/12/02	2021/01/11	rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rigid:A0H/eTxEptyOTe9UuwWFLhqEkvQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06241	uniprotkb:Q2GHU2	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	intact:EBI-26585631|ensemblbacteria:ABD44708	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26585659|imex:IM-28642-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	-	-	-	figure legend:fig.2 table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/12/02	2021/01/11	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rigid:+QhjIMUSVILY+O/ld9eT4FmaYLM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P17706	uniprotkb:Q2GHU2	intact:EBI-984930|uniprotkb:K7ENG3|uniprotkb:Q96HR2|ensembl:ENSP00000311857|uniprotkb:A8MXU3|uniprotkb:Q96AU5|uniprotkb:A8K955	intact:EBI-26585631|ensemblbacteria:ABD44708	psi-mi:ptn2_human(display_long)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26585678|imex:IM-28642-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175354(gene)|ensembl:ENST00000309660(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902206"(negative regulation of interleukin-2-mediated signaling pathway)|go:"GO:1902215"(negative regulation of interleukin-4-mediated signaling pathway)|go:"GO:1902227"(negative regulation of macrophage colony-stimulating factor signaling pathway)|go:"GO:1902233"(negative regulation of positive thymic T cell selection)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P17706|rcsb pdb:1L8K|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-6807004|refseq:NP_001193942.1|refseq:NP_002819.2|refseq:NP_536347.1|refseq:NP_536348.1	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	-	-	-	figure legend:fig.2 table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/12/02	2021/01/11	rogid:z8pewLjrIdVPp07u6Rz7xfyn76k9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rigid:L5PqbWQrn3ch28GQ2OVgeTrB6vg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q2GHU2	uniprotkb:Q01518	intact:EBI-26585631|ensemblbacteria:ABD44708	intact:EBI-2808398|ensembl:ENSP00000361878|ensembl:ENSP00000361883|ensembl:ENSP00000361891|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26585682|imex:IM-28642-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	ensembl:ENSG00000131236(gene)|ensembl:ENST00000372792(transcript)|ensembl:ENST00000372797(transcript)|ensembl:ENST00000372805(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028415|interpro:IPR028417|go:"GO:0001667"(ameboidal-type cell migration)|interpro:IPR036222|interpro:IPR036223|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|refseq:XP_005270425.1|dip:DIP-62063N	-	-	crc64:7789D1FAC0D1AB7B	figure legend:fig.2 table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/12/02	2021/01/11	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rigid:DM4aYs0zj2G6zQ86nJmc3S9Mz5I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15814	uniprotkb:Q2GHU2	intact:EBI-1222221|uniprotkb:Q0P681|ensembl:ENSP00000329312	intact:EBI-26585631|ensemblbacteria:ABD44708	psi-mi:igll1_human(display_long)|uniprotkb:IGLL1(gene name)|psi-mi:IGLL1(display_short)|uniprotkb:IGL1(gene name synonym)|uniprotkb:Immunoglobulin-related protein 14.1(gene name synonym)|uniprotkb:Immunoglobulin omega polypeptide(gene name synonym)|uniprotkb:Ig lambda-5(gene name synonym)|uniprotkb:CD179 antigen-like family member B(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26587344|imex:IM-28642-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064455.1|refseq:NP_690594.1|ensembl:ENSG00000128322(gene)|ensembl:ENST00000330377(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P15814|rcsb pdb:2H32|rcsb pdb:2H3N|rcsb pdb:2LKQ|reactome:R-HSA-202733	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	-	-	-	figure legend:fig.2 table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/12/02	2021/01/12	rogid:BpOlZ3iBc9geHAdkkOm+Z5yCsiU9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rigid:gJEJWeS8Cx/bfZRUGZg56JFSeFw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q2GHU2	uniprotkb:Q01518	intact:EBI-26585631|ensemblbacteria:ABD44708	intact:EBI-2808398|ensembl:ENSP00000361878|ensembl:ENSP00000361883|ensembl:ENSP00000361891|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26587348|imex:IM-28642-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	ensembl:ENSG00000131236(gene)|ensembl:ENST00000372792(transcript)|ensembl:ENST00000372797(transcript)|ensembl:ENST00000372805(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028415|interpro:IPR028417|go:"GO:0001667"(ameboidal-type cell migration)|interpro:IPR036222|interpro:IPR036223|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|refseq:XP_005270425.1|dip:DIP-62063N	-	-	crc64:7789D1FAC0D1AB7B	figure legend:fig.3 table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/12/02	2021/01/12	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rigid:DM4aYs0zj2G6zQ86nJmc3S9Mz5I	false	green fluorescent protein tag:n-n	beta gal tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q2GHU2	uniprotkb:P15814	intact:EBI-26585631|ensemblbacteria:ABD44708	intact:EBI-1222221|uniprotkb:Q0P681|ensembl:ENSP00000329312	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:igll1_human(display_long)|uniprotkb:IGLL1(gene name)|psi-mi:IGLL1(display_short)|uniprotkb:IGL1(gene name synonym)|uniprotkb:Immunoglobulin-related protein 14.1(gene name synonym)|uniprotkb:Immunoglobulin omega polypeptide(gene name synonym)|uniprotkb:Ig lambda-5(gene name synonym)|uniprotkb:CD179 antigen-like family member B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26587367|imex:IM-28642-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	refseq:NP_064455.1|refseq:NP_690594.1|ensembl:ENSG00000128322(gene)|ensembl:ENST00000330377(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P15814|rcsb pdb:2H32|rcsb pdb:2H3N|rcsb pdb:2LKQ|reactome:R-HSA-202733	-	-	-	figure legend:fig.3a table1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/12/02	2021/01/12	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:BpOlZ3iBc9geHAdkkOm+Z5yCsiU9606	rigid:gJEJWeS8Cx/bfZRUGZg56JFSeFw	false	green fluorescent protein tag:n-n	beta gal tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q2GHU2	uniprotkb:Q86SE9	intact:EBI-26585631|ensemblbacteria:ABD44708	intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26587378|imex:IM-28642-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N	-	-	-	figure legend:fig.3 table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/12/02	2021/01/12	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606	rigid:A0H/eTxEptyOTe9UuwWFLhqEkvQ	false	green fluorescent protein tag:n-n|sufficient binding region:127-285	beta gal tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P06241	uniprotkb:Q2GHU2	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	intact:EBI-26585631|ensemblbacteria:ABD44708	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26587389|imex:IM-28642-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	-	-	-	figure legend:fig.3 table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/12/02	2021/01/12	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rigid:+QhjIMUSVILY+O/ld9eT4FmaYLM	false	beta gal tag:n-n	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P17706	uniprotkb:Q2GHU2	intact:EBI-984930|uniprotkb:K7ENG3|uniprotkb:Q96HR2|ensembl:ENSP00000311857|uniprotkb:A8MXU3|uniprotkb:Q96AU5|uniprotkb:A8K955	intact:EBI-26585631|ensemblbacteria:ABD44708	psi-mi:ptn2_human(display_long)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26587400|imex:IM-28642-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175354(gene)|ensembl:ENST00000309660(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902206"(negative regulation of interleukin-2-mediated signaling pathway)|go:"GO:1902215"(negative regulation of interleukin-4-mediated signaling pathway)|go:"GO:1902227"(negative regulation of macrophage colony-stimulating factor signaling pathway)|go:"GO:1902233"(negative regulation of positive thymic T cell selection)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P17706|rcsb pdb:1L8K|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-6807004|refseq:NP_001193942.1|refseq:NP_002819.2|refseq:NP_536347.1|refseq:NP_536348.1	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	-	-	-	figure legend:fig.3 table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/12/02	2021/01/12	rogid:z8pewLjrIdVPp07u6Rz7xfyn76k9606	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rigid:L5PqbWQrn3ch28GQ2OVgeTrB6vg	false	beta gal tag:n-n	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q2GHU2	uniprotkb:P06241	intact:EBI-26585631|ensemblbacteria:ABD44708	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26595542|imex:IM-28642-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439	-	-	-	figure legend:fig.4a,5a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/12/02	2021/01/18	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rigid:+QhjIMUSVILY+O/ld9eT4FmaYLM	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q2GHU2	uniprotkb:P17706	intact:EBI-26585631|ensemblbacteria:ABD44708	intact:EBI-984930|uniprotkb:K7ENG3|uniprotkb:Q96HR2|ensembl:ENSP00000311857|uniprotkb:A8MXU3|uniprotkb:Q96AU5|uniprotkb:A8K955	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:ptn2_human(display_long)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26595553|imex:IM-28642-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	ensembl:ENSG00000175354(gene)|ensembl:ENST00000309660(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902206"(negative regulation of interleukin-2-mediated signaling pathway)|go:"GO:1902215"(negative regulation of interleukin-4-mediated signaling pathway)|go:"GO:1902227"(negative regulation of macrophage colony-stimulating factor signaling pathway)|go:"GO:1902233"(negative regulation of positive thymic T cell selection)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P17706|rcsb pdb:1L8K|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-6807004|refseq:NP_001193942.1|refseq:NP_002819.2|refseq:NP_536347.1|refseq:NP_536348.1	-	-	-	figure legend:fig.4b,5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/12/02	2021/01/18	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:z8pewLjrIdVPp07u6Rz7xfyn76k9606	rigid:L5PqbWQrn3ch28GQ2OVgeTrB6vg	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q2GHU2	uniprotkb:Q01518	intact:EBI-26585631|ensemblbacteria:ABD44708	intact:EBI-2808398|ensembl:ENSP00000361878|ensembl:ENSP00000361883|ensembl:ENSP00000361891|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26595559|imex:IM-28642-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	ensembl:ENSG00000131236(gene)|ensembl:ENST00000372792(transcript)|ensembl:ENST00000372797(transcript)|ensembl:ENST00000372805(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028415|interpro:IPR028417|go:"GO:0001667"(ameboidal-type cell migration)|interpro:IPR036222|interpro:IPR036223|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|refseq:XP_005270425.1|dip:DIP-62063N	-	-	crc64:7789D1FAC0D1AB7B	figure legend:fig.4c,5c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/12/02	2021/01/18	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rigid:DM4aYs0zj2G6zQ86nJmc3S9Mz5I	false	green fluorescent protein tag:n-n	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q2GHU2	uniprotkb:Q01518	intact:EBI-26585631|ensemblbacteria:ABD44708	intact:EBI-2808398|ensembl:ENSP00000361878|ensembl:ENSP00000361883|ensembl:ENSP00000361891|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26595595|imex:IM-28642-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	ensembl:ENSG00000131236(gene)|ensembl:ENST00000372792(transcript)|ensembl:ENST00000372797(transcript)|ensembl:ENST00000372805(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028415|interpro:IPR028417|go:"GO:0001667"(ameboidal-type cell migration)|interpro:IPR036222|interpro:IPR036223|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|refseq:XP_005270425.1|dip:DIP-62063N	-	-	crc64:7789D1FAC0D1AB7B	figure legend:fig.6j-l,7c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2020/12/02	2021/01/18	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606	rigid:DM4aYs0zj2G6zQ86nJmc3S9Mz5I	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q2GHU2	uniprotkb:P17706	intact:EBI-26585631|ensemblbacteria:ABD44708	intact:EBI-984930|uniprotkb:K7ENG3|uniprotkb:Q96HR2|ensembl:ENSP00000311857|uniprotkb:A8MXU3|uniprotkb:Q96AU5|uniprotkb:A8K955	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:ptn2_human(display_long)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26595608|imex:IM-28642-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	ensembl:ENSG00000175354(gene)|ensembl:ENST00000309660(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902206"(negative regulation of interleukin-2-mediated signaling pathway)|go:"GO:1902215"(negative regulation of interleukin-4-mediated signaling pathway)|go:"GO:1902227"(negative regulation of macrophage colony-stimulating factor signaling pathway)|go:"GO:1902233"(negative regulation of positive thymic T cell selection)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P17706|rcsb pdb:1L8K|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-6807004|refseq:NP_001193942.1|refseq:NP_002819.2|refseq:NP_536347.1|refseq:NP_536348.1	-	-	-	figure legend:fig.6g-i, 7b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2020/12/02	2021/01/18	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:z8pewLjrIdVPp07u6Rz7xfyn76k9606	rigid:L5PqbWQrn3ch28GQ2OVgeTrB6vg	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q2GHU2	uniprotkb:P06241	intact:EBI-26585631|ensemblbacteria:ABD44708	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26595614|imex:IM-28642-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439	-	-	-	figure legend:fig.6d-f, 7a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2020/12/02	2021/01/18	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rigid:+QhjIMUSVILY+O/ld9eT4FmaYLM	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q2GHU2	uniprotkb:Q86SE9	intact:EBI-26585631|ensemblbacteria:ABD44708	intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492	psi-mi:q2ghu2_ehrcr(display_long)|uniprotkb:ECH_0166(locus name)	psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Wakeel et al. (2009)	imex:IM-28642|pubmed:19273555	taxid:205920(strain arkansas)|taxid:205920(Ehrlichia chaffeensis)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26595618|imex:IM-28642-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:ABD44708(transcript)|ensemblbacteria:ECH_0166(gene)|mint:Q2GHU2	refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N	-	-	-	figure legend:fig.6a-c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thp-1)|taxid:9606(Homo sapiens acute monocytic leukemia cells)	-	2020/12/02	2021/01/18	rogid:rAiPhkTf/0FZdJWRuXRG4b45JPs205920	rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606	rigid:A0H/eTxEptyOTe9UuwWFLhqEkvQ	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)