#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:D3ZHX2	uniprotkb:A0A3G5BIY8	intact:EBI-25494777|ensembl:ENSRNOP00000025815	intact:EBI-25494714	psi-mi:d3zhx2_rat(display_long)|uniprotkb:Thap11(gene name)|psi-mi:Thap11(display_short)|uniprotkb:Thap11_predicted(gene name synonym)|uniprotkb:rCG_51358(orf name)	psi-mi:a0a3g5biy8_sars(display_long)|uniprotkb:3C-like proteinase(gene name synonym)|uniprotkb:Growth factor-like peptide(gene name synonym)|uniprotkb:Guanine-N7 methyltransferase(gene name synonym)|uniprotkb:Helicase(gene name synonym)|uniprotkb:Host translation inhibitor nsp1(gene name synonym)|uniprotkb:Leader protein(gene name synonym)|uniprotkb:NendoU(gene name synonym)|uniprotkb:Non-structural protein 10(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4(gene name synonym)|uniprotkb:Non-structural protein 6(gene name synonym)|uniprotkb:Non-structural protein 7(gene name synonym)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:Non-structural protein 9(gene name synonym)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:Papain-like proteinase(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Replicase polyprotein 1ab(gene name synonym)|uniprotkb:Uridylate-specific endoribonuclease(gene name synonym)|uniprotkb:p65 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2008)	pubmed:19224332|imex:IM-27843	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:228330(SARS coronavirus Urbani)|taxid:228330(SARS coronavirus Urbani)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25494797|imex:IM-27843-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000019109(gene)|ensembl:ENSRNOT00000025815(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rgd:1310268|refseq:NP_001100892.1	go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0032259"(methylation)|go:"GO:0033644"(host cell membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR044315|interpro:IPR044322|interpro:IPR044330|interpro:IPR044343|interpro:IPR044351|interpro:IPR044353|interpro:IPR044357|interpro:IPR044367|interpro:IPR044371|interpro:IPR044374|interpro:IPR044389|interpro:IPR044401|interpro:IPR027351|interpro:IPR032505|interpro:IPR009461(Coronavirus NSP13)|interpro:IPR027352|interpro:IPR037227|interpro:IPR002589(Appr-1-p processing)|interpro:IPR032592|interpro:IPR042570|interpro:IPR021590|interpro:IPR036333|interpro:IPR009466(NSP11)|interpro:IPR042515|interpro:IPR038030|interpro:IPR024375|interpro:IPR038400|interpro:IPR022733|interpro:IPR038166|interpro:IPR038123|interpro:IPR014828(Nsp7 replicase)|interpro:IPR037204|interpro:IPR014829(Nsp8 replicase)|interpro:IPR037230|interpro:IPR014822(Nsp9 replicase)|interpro:IPR036499|interpro:IPR027417|interpro:IPR008740(Peptidase C30, Coronavirus endopeptidase)|interpro:IPR013016(Peptidase C30/C16)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR038083|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009469(RNA polymerase, N-terminal, coronaviral)|interpro:IPR018995|interpro:IPR029063|interpro:IPR024358|interpro:IPR043174|interpro:IPR043177|interpro:IPR043178|interpro:IPR043472|interpro:IPR043477|interpro:IPR043478|interpro:IPR043502|interpro:IPR043503|interpro:IPR043504|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR043606|interpro:IPR043608|interpro:IPR043609|interpro:IPR043610|interpro:IPR043611|interpro:IPR043612|interpro:IPR043613|interpro:IPR043615	-	-	-	figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/30	2020/03/30	rogid:LE92SXQEMF0CvdO+38gXINqILg810116	rogid:l6i3G0dCddewvkIpRrSdLjyoUik228330	rigid:166NaMGClVxiKAyG5tStXIjXH7w	false	-	sufficient binding region:5558..5558-5909..5909(IPR027351)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q4KLI0	uniprotkb:A0A3G5BIY8	intact:EBI-689316|uniprotkb:G3V935|ensembl:ENSRNOP00000034916|ensembl:ENSRNOP00000070723	intact:EBI-25494714	psi-mi:q4kli0_rat(display_long)|uniprotkb:Smarcb1(gene name)|psi-mi:Smarcb1(display_short)|uniprotkb:LOC103694876(gene name synonym)|uniprotkb:rCG_60662(orf name)	psi-mi:a0a3g5biy8_sars(display_long)|uniprotkb:3C-like proteinase(gene name synonym)|uniprotkb:Growth factor-like peptide(gene name synonym)|uniprotkb:Guanine-N7 methyltransferase(gene name synonym)|uniprotkb:Helicase(gene name synonym)|uniprotkb:Host translation inhibitor nsp1(gene name synonym)|uniprotkb:Leader protein(gene name synonym)|uniprotkb:NendoU(gene name synonym)|uniprotkb:Non-structural protein 10(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4(gene name synonym)|uniprotkb:Non-structural protein 6(gene name synonym)|uniprotkb:Non-structural protein 7(gene name synonym)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:Non-structural protein 9(gene name synonym)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:Papain-like proteinase(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Replicase polyprotein 1ab(gene name synonym)|uniprotkb:Uridylate-specific endoribonuclease(gene name synonym)|uniprotkb:p65 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2008)	pubmed:19224332|imex:IM-27843	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:228330(SARS coronavirus Urbani)|taxid:228330(SARS coronavirus Urbani)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25494804|imex:IM-27843-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:1308761|refseq:NP_001020899.1|refseq:XP_008772066.1|rgd:9203817|ensembl:ENSRNOG00000028302(gene)|ensembl:ENSRNOG00000061740(gene)|ensembl:ENSRNOT00000029458(transcript)|ensembl:ENSRNOT00000083835(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001741"(XY body)|go:"GO:0001824"(blastocyst development)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|reactome:R-RNO-3214858|reactome:R-RNO-8939243	go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0032259"(methylation)|go:"GO:0033644"(host cell membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR044315|interpro:IPR044322|interpro:IPR044330|interpro:IPR044343|interpro:IPR044351|interpro:IPR044353|interpro:IPR044357|interpro:IPR044367|interpro:IPR044371|interpro:IPR044374|interpro:IPR044389|interpro:IPR044401|interpro:IPR027351|interpro:IPR032505|interpro:IPR009461(Coronavirus NSP13)|interpro:IPR027352|interpro:IPR037227|interpro:IPR002589(Appr-1-p processing)|interpro:IPR032592|interpro:IPR042570|interpro:IPR021590|interpro:IPR036333|interpro:IPR009466(NSP11)|interpro:IPR042515|interpro:IPR038030|interpro:IPR024375|interpro:IPR038400|interpro:IPR022733|interpro:IPR038166|interpro:IPR038123|interpro:IPR014828(Nsp7 replicase)|interpro:IPR037204|interpro:IPR014829(Nsp8 replicase)|interpro:IPR037230|interpro:IPR014822(Nsp9 replicase)|interpro:IPR036499|interpro:IPR027417|interpro:IPR008740(Peptidase C30, Coronavirus endopeptidase)|interpro:IPR013016(Peptidase C30/C16)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR038083|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009469(RNA polymerase, N-terminal, coronaviral)|interpro:IPR018995|interpro:IPR029063|interpro:IPR024358|interpro:IPR043174|interpro:IPR043177|interpro:IPR043178|interpro:IPR043472|interpro:IPR043477|interpro:IPR043478|interpro:IPR043502|interpro:IPR043503|interpro:IPR043504|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR043606|interpro:IPR043608|interpro:IPR043609|interpro:IPR043610|interpro:IPR043611|interpro:IPR043612|interpro:IPR043613|interpro:IPR043615	-	-	-	figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/30	2020/03/30	rogid:nCACo1KHiMlwp3pROvLzVFOl5pE10116	rogid:l6i3G0dCddewvkIpRrSdLjyoUik228330	rigid:vBhoafNcAKrDECQ1zc1TYRa1vNw	false	-	sufficient binding region:5558..5558-5909..5909(IPR027351)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A3G5BIY8	uniprotkb:Q6AYI1	intact:EBI-25494714	intact:EBI-931635|ensembl:ENSRNOP00000041663	psi-mi:a0a3g5biy8_sars(display_long)|uniprotkb:3C-like proteinase(gene name synonym)|uniprotkb:Growth factor-like peptide(gene name synonym)|uniprotkb:Guanine-N7 methyltransferase(gene name synonym)|uniprotkb:Helicase(gene name synonym)|uniprotkb:Host translation inhibitor nsp1(gene name synonym)|uniprotkb:Leader protein(gene name synonym)|uniprotkb:NendoU(gene name synonym)|uniprotkb:Non-structural protein 10(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4(gene name synonym)|uniprotkb:Non-structural protein 6(gene name synonym)|uniprotkb:Non-structural protein 7(gene name synonym)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:Non-structural protein 9(gene name synonym)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:Papain-like proteinase(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Replicase polyprotein 1ab(gene name synonym)|uniprotkb:Uridylate-specific endoribonuclease(gene name synonym)|uniprotkb:p65 homolog(gene name synonym)	psi-mi:q6ayi1_rat(display_long)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Probable ATP-dependent RNA helicase DDX5(gene name synonym)|uniprotkb:rCG_35034(orf name)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2008)	pubmed:19224332|imex:IM-27843	taxid:228330(SARS coronavirus Urbani)|taxid:228330(SARS coronavirus Urbani)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25494829|imex:IM-27843-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0032259"(methylation)|go:"GO:0033644"(host cell membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR044315|interpro:IPR044322|interpro:IPR044330|interpro:IPR044343|interpro:IPR044351|interpro:IPR044353|interpro:IPR044357|interpro:IPR044367|interpro:IPR044371|interpro:IPR044374|interpro:IPR044389|interpro:IPR044401|interpro:IPR027351|interpro:IPR032505|interpro:IPR009461(Coronavirus NSP13)|interpro:IPR027352|interpro:IPR037227|interpro:IPR002589(Appr-1-p processing)|interpro:IPR032592|interpro:IPR042570|interpro:IPR021590|interpro:IPR036333|interpro:IPR009466(NSP11)|interpro:IPR042515|interpro:IPR038030|interpro:IPR024375|interpro:IPR038400|interpro:IPR022733|interpro:IPR038166|interpro:IPR038123|interpro:IPR014828(Nsp7 replicase)|interpro:IPR037204|interpro:IPR014829(Nsp8 replicase)|interpro:IPR037230|interpro:IPR014822(Nsp9 replicase)|interpro:IPR036499|interpro:IPR027417|interpro:IPR008740(Peptidase C30, Coronavirus endopeptidase)|interpro:IPR013016(Peptidase C30/C16)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR038083|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009469(RNA polymerase, N-terminal, coronaviral)|interpro:IPR018995|interpro:IPR029063|interpro:IPR024358|interpro:IPR043174|interpro:IPR043177|interpro:IPR043178|interpro:IPR043472|interpro:IPR043477|interpro:IPR043478|interpro:IPR043502|interpro:IPR043503|interpro:IPR043504|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR043606|interpro:IPR043608|interpro:IPR043609|interpro:IPR043610|interpro:IPR043611|interpro:IPR043612|interpro:IPR043613|interpro:IPR043615	rgd:619906|refseq:NP_001007614.1|refseq:XP_008766535.1|ensembl:ENSRNOG00000030680(gene)|ensembl:ENSRNOT00000048490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-RNO-3899300|reactome:R-RNO-72163|reactome:R-RNO-9018519	-	-	-	figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/30	2020/03/30	rogid:l6i3G0dCddewvkIpRrSdLjyoUik228330	rogid:MiLWQ8hublA83RxlL984FW1wYNk10116	rigid:dBq1YapQBYEUNVn8u2ScFylmcto	false	sufficient binding region:5558..5558-5909..5909(IPR027351)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:B5DFM8	uniprotkb:A0A3G5BIY8	intact:EBI-22240024|ensembl:ENSRNOP00000025592	intact:EBI-25494714	psi-mi:b5dfm8_rat(display_long)|uniprotkb:Bcas2(gene name)|psi-mi:Bcas2(display_short)|uniprotkb:Bcas2_predicted(gene name synonym)|uniprotkb:rCG_51877(orf name)	psi-mi:a0a3g5biy8_sars(display_long)|uniprotkb:3C-like proteinase(gene name synonym)|uniprotkb:Growth factor-like peptide(gene name synonym)|uniprotkb:Guanine-N7 methyltransferase(gene name synonym)|uniprotkb:Helicase(gene name synonym)|uniprotkb:Host translation inhibitor nsp1(gene name synonym)|uniprotkb:Leader protein(gene name synonym)|uniprotkb:NendoU(gene name synonym)|uniprotkb:Non-structural protein 10(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4(gene name synonym)|uniprotkb:Non-structural protein 6(gene name synonym)|uniprotkb:Non-structural protein 7(gene name synonym)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:Non-structural protein 9(gene name synonym)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:Papain-like proteinase(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Replicase polyprotein 1ab(gene name synonym)|uniprotkb:Uridylate-specific endoribonuclease(gene name synonym)|uniprotkb:p65 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2008)	pubmed:19224332|imex:IM-27843	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:228330(SARS coronavirus Urbani)|taxid:228330(SARS coronavirus Urbani)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25494836|imex:IM-27843-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000018783(gene)|ensembl:ENSRNOT00000025592(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005813"(centrosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR008409(Breast carcinoma amplified sequence 2)|reactome:R-RNO-72163|rgd:1306485|refseq:NP_001099928.1	go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0032259"(methylation)|go:"GO:0033644"(host cell membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR044315|interpro:IPR044322|interpro:IPR044330|interpro:IPR044343|interpro:IPR044351|interpro:IPR044353|interpro:IPR044357|interpro:IPR044367|interpro:IPR044371|interpro:IPR044374|interpro:IPR044389|interpro:IPR044401|interpro:IPR027351|interpro:IPR032505|interpro:IPR009461(Coronavirus NSP13)|interpro:IPR027352|interpro:IPR037227|interpro:IPR002589(Appr-1-p processing)|interpro:IPR032592|interpro:IPR042570|interpro:IPR021590|interpro:IPR036333|interpro:IPR009466(NSP11)|interpro:IPR042515|interpro:IPR038030|interpro:IPR024375|interpro:IPR038400|interpro:IPR022733|interpro:IPR038166|interpro:IPR038123|interpro:IPR014828(Nsp7 replicase)|interpro:IPR037204|interpro:IPR014829(Nsp8 replicase)|interpro:IPR037230|interpro:IPR014822(Nsp9 replicase)|interpro:IPR036499|interpro:IPR027417|interpro:IPR008740(Peptidase C30, Coronavirus endopeptidase)|interpro:IPR013016(Peptidase C30/C16)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR038083|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009469(RNA polymerase, N-terminal, coronaviral)|interpro:IPR018995|interpro:IPR029063|interpro:IPR024358|interpro:IPR043174|interpro:IPR043177|interpro:IPR043178|interpro:IPR043472|interpro:IPR043477|interpro:IPR043478|interpro:IPR043502|interpro:IPR043503|interpro:IPR043504|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR043606|interpro:IPR043608|interpro:IPR043609|interpro:IPR043610|interpro:IPR043611|interpro:IPR043612|interpro:IPR043613|interpro:IPR043615	-	-	-	figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/30	2020/03/30	rogid:FXkx4PXKSo8k8AANNA1ihcCzVDo10116	rogid:l6i3G0dCddewvkIpRrSdLjyoUik228330	rigid:/Us9I5eoUB4PPDjbMhMRXoK1VKM	false	-	sufficient binding region:5558..5558-5909..5909(IPR027351)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q920P6	uniprotkb:A0A3G5BIY8	intact:EBI-25494877|ensembl:ENSRNOP00000014151	intact:EBI-25494714	psi-mi:ada_rat(display_long)|uniprotkb:Ada(gene name)|psi-mi:Ada(display_short)|uniprotkb:Adenosine aminohydrolase(gene name synonym)	psi-mi:a0a3g5biy8_sars(display_long)|uniprotkb:3C-like proteinase(gene name synonym)|uniprotkb:Growth factor-like peptide(gene name synonym)|uniprotkb:Guanine-N7 methyltransferase(gene name synonym)|uniprotkb:Helicase(gene name synonym)|uniprotkb:Host translation inhibitor nsp1(gene name synonym)|uniprotkb:Leader protein(gene name synonym)|uniprotkb:NendoU(gene name synonym)|uniprotkb:Non-structural protein 10(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4(gene name synonym)|uniprotkb:Non-structural protein 6(gene name synonym)|uniprotkb:Non-structural protein 7(gene name synonym)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:Non-structural protein 9(gene name synonym)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:Papain-like proteinase(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Replicase polyprotein 1ab(gene name synonym)|uniprotkb:Uridylate-specific endoribonuclease(gene name synonym)|uniprotkb:p65 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2008)	pubmed:19224332|imex:IM-27843	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:228330(SARS coronavirus Urbani)|taxid:228330(SARS coronavirus Urbani)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25494955|imex:IM-27843-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000010265(gene)|ensembl:ENSRNOT00000014151(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001821"(histamine secretion)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001883"(purine nucleoside binding)|go:"GO:0001889"(liver development)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0002686"(negative regulation of leukocyte migration)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006154"(adenosine catabolic process)|go:"GO:0001890"(placenta development)|go:"GO:0006157"(deoxyadenosine catabolic process)|go:"GO:0006196"(AMP catabolic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007568"(aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0016020"(membrane)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0030054"(cell junction)|go:"GO:0030324"(lung development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032261"(purine nucleotide salvage)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033632"(regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042110"(T cell activation)|go:"GO:0042323"(negative regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0043278"(response to morphine)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046059"(dAMP catabolic process)|go:"GO:0060407"(negative regulation of penile erection)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0070256"(negative regulation of mucus secretion)|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006330(Adenosine deaminase)|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR028893|interpro:IPR032466|reactome:R-RNO-74217|go:"GO:0046061"(dATP catabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046101"(hypoxanthine biosynthetic process)|go:"GO:0046103"(inosine biosynthetic process)|go:"GO:0046111"(xanthine biosynthetic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046936"(2'-deoxyadenosine deaminase activity)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0060169"(negative regulation of adenosine receptor signaling pathway)|go:"GO:0060205"(cytoplasmic vesicle lumen)|rgd:2031|refseq:NP_569083.1	go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0032259"(methylation)|go:"GO:0033644"(host cell membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR044315|interpro:IPR044322|interpro:IPR044330|interpro:IPR044343|interpro:IPR044351|interpro:IPR044353|interpro:IPR044357|interpro:IPR044367|interpro:IPR044371|interpro:IPR044374|interpro:IPR044389|interpro:IPR044401|interpro:IPR027351|interpro:IPR032505|interpro:IPR009461(Coronavirus NSP13)|interpro:IPR027352|interpro:IPR037227|interpro:IPR002589(Appr-1-p processing)|interpro:IPR032592|interpro:IPR042570|interpro:IPR021590|interpro:IPR036333|interpro:IPR009466(NSP11)|interpro:IPR042515|interpro:IPR038030|interpro:IPR024375|interpro:IPR038400|interpro:IPR022733|interpro:IPR038166|interpro:IPR038123|interpro:IPR014828(Nsp7 replicase)|interpro:IPR037204|interpro:IPR014829(Nsp8 replicase)|interpro:IPR037230|interpro:IPR014822(Nsp9 replicase)|interpro:IPR036499|interpro:IPR027417|interpro:IPR008740(Peptidase C30, Coronavirus endopeptidase)|interpro:IPR013016(Peptidase C30/C16)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR038083|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009469(RNA polymerase, N-terminal, coronaviral)|interpro:IPR018995|interpro:IPR029063|interpro:IPR024358|interpro:IPR043174|interpro:IPR043177|interpro:IPR043178|interpro:IPR043472|interpro:IPR043477|interpro:IPR043478|interpro:IPR043502|interpro:IPR043503|interpro:IPR043504|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR043606|interpro:IPR043608|interpro:IPR043609|interpro:IPR043610|interpro:IPR043611|interpro:IPR043612|interpro:IPR043613|interpro:IPR043615	-	-	-	figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/30	2020/03/30	rogid:5AjtcspbjwzDP0Xswnn1KTu/mGU10116	rogid:l6i3G0dCddewvkIpRrSdLjyoUik228330	rigid:HXeX7MqqXagpTcCyhUcnVLyMTeI	false	-	sufficient binding region:5558..5558-5909..5909(IPR027351)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q3KRD0	uniprotkb:A0A3G5BIY8	intact:EBI-25494963|ensembl:ENSRNOP00000003828	intact:EBI-25494714	psi-mi:sydm_rat(display_long)|uniprotkb:Dars2(gene name)|psi-mi:Dars2(display_short)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym)	psi-mi:a0a3g5biy8_sars(display_long)|uniprotkb:3C-like proteinase(gene name synonym)|uniprotkb:Growth factor-like peptide(gene name synonym)|uniprotkb:Guanine-N7 methyltransferase(gene name synonym)|uniprotkb:Helicase(gene name synonym)|uniprotkb:Host translation inhibitor nsp1(gene name synonym)|uniprotkb:Leader protein(gene name synonym)|uniprotkb:NendoU(gene name synonym)|uniprotkb:Non-structural protein 10(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4(gene name synonym)|uniprotkb:Non-structural protein 6(gene name synonym)|uniprotkb:Non-structural protein 7(gene name synonym)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:Non-structural protein 9(gene name synonym)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:Papain-like proteinase(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Replicase polyprotein 1ab(gene name synonym)|uniprotkb:Uridylate-specific endoribonuclease(gene name synonym)|uniprotkb:p65 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2008)	pubmed:19224332|imex:IM-27843	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:228330(SARS coronavirus Urbani)|taxid:228330(SARS coronavirus Urbani)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25494988|imex:IM-27843-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043039"(tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|go:"GO:0070145"(mitochondrial asparaginyl-tRNA aminoacylation)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR029351|ensembl:ENSRNOG00000002813(gene)|ensembl:ENSRNOT00000003828(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0042803"(protein homodimerization activity)|rgd:1308286|refseq:NP_001029315.1	go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0032259"(methylation)|go:"GO:0033644"(host cell membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR044315|interpro:IPR044322|interpro:IPR044330|interpro:IPR044343|interpro:IPR044351|interpro:IPR044353|interpro:IPR044357|interpro:IPR044367|interpro:IPR044371|interpro:IPR044374|interpro:IPR044389|interpro:IPR044401|interpro:IPR027351|interpro:IPR032505|interpro:IPR009461(Coronavirus NSP13)|interpro:IPR027352|interpro:IPR037227|interpro:IPR002589(Appr-1-p processing)|interpro:IPR032592|interpro:IPR042570|interpro:IPR021590|interpro:IPR036333|interpro:IPR009466(NSP11)|interpro:IPR042515|interpro:IPR038030|interpro:IPR024375|interpro:IPR038400|interpro:IPR022733|interpro:IPR038166|interpro:IPR038123|interpro:IPR014828(Nsp7 replicase)|interpro:IPR037204|interpro:IPR014829(Nsp8 replicase)|interpro:IPR037230|interpro:IPR014822(Nsp9 replicase)|interpro:IPR036499|interpro:IPR027417|interpro:IPR008740(Peptidase C30, Coronavirus endopeptidase)|interpro:IPR013016(Peptidase C30/C16)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR038083|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009469(RNA polymerase, N-terminal, coronaviral)|interpro:IPR018995|interpro:IPR029063|interpro:IPR024358|interpro:IPR043174|interpro:IPR043177|interpro:IPR043178|interpro:IPR043472|interpro:IPR043477|interpro:IPR043478|interpro:IPR043502|interpro:IPR043503|interpro:IPR043504|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR043606|interpro:IPR043608|interpro:IPR043609|interpro:IPR043610|interpro:IPR043611|interpro:IPR043612|interpro:IPR043613|interpro:IPR043615	-	-	-	figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/30	2020/03/30	rogid:5KtdnSOmz6ZD/rTBdGJ7nQoOhsI10116	rogid:l6i3G0dCddewvkIpRrSdLjyoUik228330	rigid:vGgs9fuSI07jNo6yIRbij4NK3fc	false	-	sufficient binding region:5558..5558-5909..5909(IPR027351)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:D3ZCV0	uniprotkb:A0A3G5BIY8	intact:EBI-6257410|ensembl:ENSRNOP00000024098	intact:EBI-25494714	psi-mi:d3zcv0_rat(display_long)|uniprotkb:Actn2(gene name)|psi-mi:Actn2(display_short)|uniprotkb:rCG_30552(orf name)	psi-mi:a0a3g5biy8_sars(display_long)|uniprotkb:3C-like proteinase(gene name synonym)|uniprotkb:Growth factor-like peptide(gene name synonym)|uniprotkb:Guanine-N7 methyltransferase(gene name synonym)|uniprotkb:Helicase(gene name synonym)|uniprotkb:Host translation inhibitor nsp1(gene name synonym)|uniprotkb:Leader protein(gene name synonym)|uniprotkb:NendoU(gene name synonym)|uniprotkb:Non-structural protein 10(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4(gene name synonym)|uniprotkb:Non-structural protein 6(gene name synonym)|uniprotkb:Non-structural protein 7(gene name synonym)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:Non-structural protein 9(gene name synonym)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:Papain-like proteinase(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Replicase polyprotein 1ab(gene name synonym)|uniprotkb:Uridylate-specific endoribonuclease(gene name synonym)|uniprotkb:p65 homolog(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chen et al. (2008)	pubmed:19224332|imex:IM-27843	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:228330(SARS coronavirus Urbani)|taxid:228330(SARS coronavirus Urbani)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25494996|imex:IM-27843-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000017833(gene)|ensembl:ENSRNOT00000024098(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030035"(microspike assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031432"(titin binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051373"(FATZ binding)|go:"GO:0051695"(actin filament uncapping)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070080"(titin Z domain binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2001137"(positive regulation of endocytic recycling)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|mint:D3ZCV0|reactome:R-RNO-114608|reactome:R-RNO-390522|reactome:R-RNO-438066|reactome:R-RNO-5673001|rgd:1308097|refseq:NP_001163796.1	go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0032259"(methylation)|go:"GO:0033644"(host cell membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR044315|interpro:IPR044322|interpro:IPR044330|interpro:IPR044343|interpro:IPR044351|interpro:IPR044353|interpro:IPR044357|interpro:IPR044367|interpro:IPR044371|interpro:IPR044374|interpro:IPR044389|interpro:IPR044401|interpro:IPR027351|interpro:IPR032505|interpro:IPR009461(Coronavirus NSP13)|interpro:IPR027352|interpro:IPR037227|interpro:IPR002589(Appr-1-p processing)|interpro:IPR032592|interpro:IPR042570|interpro:IPR021590|interpro:IPR036333|interpro:IPR009466(NSP11)|interpro:IPR042515|interpro:IPR038030|interpro:IPR024375|interpro:IPR038400|interpro:IPR022733|interpro:IPR038166|interpro:IPR038123|interpro:IPR014828(Nsp7 replicase)|interpro:IPR037204|interpro:IPR014829(Nsp8 replicase)|interpro:IPR037230|interpro:IPR014822(Nsp9 replicase)|interpro:IPR036499|interpro:IPR027417|interpro:IPR008740(Peptidase C30, Coronavirus endopeptidase)|interpro:IPR013016(Peptidase C30/C16)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR038083|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009469(RNA polymerase, N-terminal, coronaviral)|interpro:IPR018995|interpro:IPR029063|interpro:IPR024358|interpro:IPR043174|interpro:IPR043177|interpro:IPR043178|interpro:IPR043472|interpro:IPR043477|interpro:IPR043478|interpro:IPR043502|interpro:IPR043503|interpro:IPR043504|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR043606|interpro:IPR043608|interpro:IPR043609|interpro:IPR043610|interpro:IPR043611|interpro:IPR043612|interpro:IPR043613|interpro:IPR043615	-	-	-	figure legend:Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/30	2020/03/30	rogid:r5g0YjP9pqmJjxEfxmBL7xMzjBI10116	rogid:l6i3G0dCddewvkIpRrSdLjyoUik228330	rigid:WM9/CtuomqpJdSm2reTy7gQXWt0	false	-	sufficient binding region:5558..5558-5909..5909(IPR027351)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:A0A3G5BIY8	uniprotkb:Q6AYI1	intact:EBI-25494714	intact:EBI-931635|ensembl:ENSRNOP00000041663	psi-mi:a0a3g5biy8_sars(display_long)|uniprotkb:3C-like proteinase(gene name synonym)|uniprotkb:Growth factor-like peptide(gene name synonym)|uniprotkb:Guanine-N7 methyltransferase(gene name synonym)|uniprotkb:Helicase(gene name synonym)|uniprotkb:Host translation inhibitor nsp1(gene name synonym)|uniprotkb:Leader protein(gene name synonym)|uniprotkb:NendoU(gene name synonym)|uniprotkb:Non-structural protein 10(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4(gene name synonym)|uniprotkb:Non-structural protein 6(gene name synonym)|uniprotkb:Non-structural protein 7(gene name synonym)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:Non-structural protein 9(gene name synonym)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:Papain-like proteinase(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Replicase polyprotein 1ab(gene name synonym)|uniprotkb:Uridylate-specific endoribonuclease(gene name synonym)|uniprotkb:p65 homolog(gene name synonym)	psi-mi:q6ayi1_rat(display_long)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Probable ATP-dependent RNA helicase DDX5(gene name synonym)|uniprotkb:rCG_35034(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chen et al. (2008)	pubmed:19224332|imex:IM-27843	taxid:228330(SARS coronavirus Urbani)|taxid:228330(SARS coronavirus Urbani)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25495167|imex:IM-27843-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0032259"(methylation)|go:"GO:0033644"(host cell membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR044315|interpro:IPR044322|interpro:IPR044330|interpro:IPR044343|interpro:IPR044351|interpro:IPR044353|interpro:IPR044357|interpro:IPR044367|interpro:IPR044371|interpro:IPR044374|interpro:IPR044389|interpro:IPR044401|interpro:IPR027351|interpro:IPR032505|interpro:IPR009461(Coronavirus NSP13)|interpro:IPR027352|interpro:IPR037227|interpro:IPR002589(Appr-1-p processing)|interpro:IPR032592|interpro:IPR042570|interpro:IPR021590|interpro:IPR036333|interpro:IPR009466(NSP11)|interpro:IPR042515|interpro:IPR038030|interpro:IPR024375|interpro:IPR038400|interpro:IPR022733|interpro:IPR038166|interpro:IPR038123|interpro:IPR014828(Nsp7 replicase)|interpro:IPR037204|interpro:IPR014829(Nsp8 replicase)|interpro:IPR037230|interpro:IPR014822(Nsp9 replicase)|interpro:IPR036499|interpro:IPR027417|interpro:IPR008740(Peptidase C30, Coronavirus endopeptidase)|interpro:IPR013016(Peptidase C30/C16)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR038083|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009469(RNA polymerase, N-terminal, coronaviral)|interpro:IPR018995|interpro:IPR029063|interpro:IPR024358|interpro:IPR043174|interpro:IPR043177|interpro:IPR043178|interpro:IPR043472|interpro:IPR043477|interpro:IPR043478|interpro:IPR043502|interpro:IPR043503|interpro:IPR043504|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR043606|interpro:IPR043608|interpro:IPR043609|interpro:IPR043610|interpro:IPR043611|interpro:IPR043612|interpro:IPR043613|interpro:IPR043615	rgd:619906|refseq:NP_001007614.1|refseq:XP_008766535.1|ensembl:ENSRNOG00000030680(gene)|ensembl:ENSRNOT00000048490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-RNO-3899300|reactome:R-RNO-72163|reactome:R-RNO-9018519	-	-	-	figure legend:Fig. 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2020/03/30	2020/03/30	rogid:l6i3G0dCddewvkIpRrSdLjyoUik228330	rogid:MiLWQ8hublA83RxlL984FW1wYNk10116	rigid:dBq1YapQBYEUNVn8u2ScFylmcto	false	ha tag:?-?|sufficient binding region:5558..5558-5909..5909	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A0A3G5BIY8	uniprotkb:Q6AYI1	intact:EBI-25494714	intact:EBI-931635|ensembl:ENSRNOP00000041663	psi-mi:a0a3g5biy8_sars(display_long)|uniprotkb:3C-like proteinase(gene name synonym)|uniprotkb:Growth factor-like peptide(gene name synonym)|uniprotkb:Guanine-N7 methyltransferase(gene name synonym)|uniprotkb:Helicase(gene name synonym)|uniprotkb:Host translation inhibitor nsp1(gene name synonym)|uniprotkb:Leader protein(gene name synonym)|uniprotkb:NendoU(gene name synonym)|uniprotkb:Non-structural protein 10(gene name synonym)|uniprotkb:Non-structural protein 2(gene name synonym)|uniprotkb:Non-structural protein 3(gene name synonym)|uniprotkb:Non-structural protein 4(gene name synonym)|uniprotkb:Non-structural protein 6(gene name synonym)|uniprotkb:Non-structural protein 7(gene name synonym)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:Non-structural protein 9(gene name synonym)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:Papain-like proteinase(gene name synonym)|uniprotkb:RNA-directed RNA polymerase(gene name synonym)|uniprotkb:Replicase polyprotein 1ab(gene name synonym)|uniprotkb:Uridylate-specific endoribonuclease(gene name synonym)|uniprotkb:p65 homolog(gene name synonym)	psi-mi:q6ayi1_rat(display_long)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Probable ATP-dependent RNA helicase DDX5(gene name synonym)|uniprotkb:rCG_35034(orf name)	psi-mi:"MI:0728"(gal4 vp16 complementation)	Chen et al. (2008)	pubmed:19224332|imex:IM-27843	taxid:228330(SARS coronavirus Urbani)|taxid:228330(SARS coronavirus Urbani)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25495258|imex:IM-27843-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0032259"(methylation)|go:"GO:0033644"(host cell membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR044315|interpro:IPR044322|interpro:IPR044330|interpro:IPR044343|interpro:IPR044351|interpro:IPR044353|interpro:IPR044357|interpro:IPR044367|interpro:IPR044371|interpro:IPR044374|interpro:IPR044389|interpro:IPR044401|interpro:IPR027351|interpro:IPR032505|interpro:IPR009461(Coronavirus NSP13)|interpro:IPR027352|interpro:IPR037227|interpro:IPR002589(Appr-1-p processing)|interpro:IPR032592|interpro:IPR042570|interpro:IPR021590|interpro:IPR036333|interpro:IPR009466(NSP11)|interpro:IPR042515|interpro:IPR038030|interpro:IPR024375|interpro:IPR038400|interpro:IPR022733|interpro:IPR038166|interpro:IPR038123|interpro:IPR014828(Nsp7 replicase)|interpro:IPR037204|interpro:IPR014829(Nsp8 replicase)|interpro:IPR037230|interpro:IPR014822(Nsp9 replicase)|interpro:IPR036499|interpro:IPR027417|interpro:IPR008740(Peptidase C30, Coronavirus endopeptidase)|interpro:IPR013016(Peptidase C30/C16)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR038083|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009469(RNA polymerase, N-terminal, coronaviral)|interpro:IPR018995|interpro:IPR029063|interpro:IPR024358|interpro:IPR043174|interpro:IPR043177|interpro:IPR043178|interpro:IPR043472|interpro:IPR043477|interpro:IPR043478|interpro:IPR043502|interpro:IPR043503|interpro:IPR043504|interpro:IPR001205(RNA-directed RNA polymerase, P3D protein)|interpro:IPR043606|interpro:IPR043608|interpro:IPR043609|interpro:IPR043610|interpro:IPR043611|interpro:IPR043612|interpro:IPR043613|interpro:IPR043615	rgd:619906|refseq:NP_001007614.1|refseq:XP_008766535.1|ensembl:ENSRNOG00000030680(gene)|ensembl:ENSRNOT00000048490(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-RNO-3899300|reactome:R-RNO-72163|reactome:R-RNO-9018519	-	-	-	figure legend:Table 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line)	-	2020/03/30	2020/03/30	rogid:l6i3G0dCddewvkIpRrSdLjyoUik228330	rogid:MiLWQ8hublA83RxlL984FW1wYNk10116	rigid:dBq1YapQBYEUNVn8u2ScFylmcto	false	sufficient binding region:5558..5558-5909..5909(IPR027351)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)