#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04114	uniprotkb:P02647	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	intact:EBI-701692|uniprotkb:Q6LDN9|uniprotkb:Q6Q785|uniprotkb:A8K866|uniprotkb:Q9UCS8|uniprotkb:Q9UCT8|ensembl:ENSP00000236850|ensembl:ENSP00000352471|ensembl:ENSP00000364469|ensembl:ENSP00000364472	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:apoa1_human(display_long)|uniprotkb:APOA1(gene name)|psi-mi:APOA1(display_short)|uniprotkb:Apolipoprotein A1(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Rutledge et al. (2009)	pubmed:19164805|imex:IM-27675	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596734|imex:IM-27675-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N	refseq:NP_000030.1|refseq:NP_001304946.1|refseq:NP_001304947.1|refseq:NP_001304950.1|dip:DIP-29619N|ensembl:ENSG00000118137(gene)|ensembl:ENST00000236850(transcript)|ensembl:ENST00000359492(transcript)|ensembl:ENST00000375320(transcript)|ensembl:ENST00000375323(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0019899"(enzyme binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051180"(vitamin transport)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070508"(cholesterol import)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:P02647|rcsb pdb:1AV1|rcsb pdb:1GW3|rcsb pdb:1GW4|rcsb pdb:1ODP|rcsb pdb:1ODQ|rcsb pdb:1ODR|rcsb pdb:2MSC|rcsb pdb:2MSD|rcsb pdb:2MSE|rcsb pdb:2N5E|rcsb pdb:3K2S|rcsb pdb:3R2P|rcsb pdb:4V6M|rcsb pdb:6CC9|rcsb pdb:6CCH|rcsb pdb:6CCX|rcsb pdb:6CLZ|rcsb pdb:6CM1|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6W4E|rcsb pdb:6W4F|rcsb pdb:7KJR|reactome:R-HSA-114608|reactome:R-HSA-1369062|reactome:R-HSA-1989781|reactome:R-HSA-2168880|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-381426|reactome:R-HSA-5682113|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963896|reactome:R-HSA-8963901|reactome:R-HSA-8964011|reactome:R-HSA-8964058|reactome:R-HSA-9707616|reactome:R-HSA-975634|reactome:R-HSA-977225	-	-	-	figure legend:1B, 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).")	-	2020/01/09	2020/05/11	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	rogid:yEzPDeU8Uu/43dkLLOBAy6ey1vs9606	rigid:Sl+rIX4CWDdXQmxKOJghzo8j9u4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04114	uniprotkb:Q9BQE4	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name)	psi-mi:"MI:0030"(cross-linking study)	Rutledge et al. (2009)	pubmed:19164805|imex:IM-27675	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596734|imex:IM-27675-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N	refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)	-	-	-	figure legend:1B, 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).")	-	2020/01/09	2020/05/11	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606	rigid:Sl+rIX4CWDdXQmxKOJghzo8j9u4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04114	uniprotkb:Q9BUN8	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Rutledge et al. (2009)	pubmed:19164805|imex:IM-27675	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596734|imex:IM-27675-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	-	-	-	figure legend:1B, 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).")	-	2020/01/09	2020/05/11	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rigid:Sl+rIX4CWDdXQmxKOJghzo8j9u4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04114	uniprotkb:Q86TM6	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Rutledge et al. (2009)	pubmed:19164805|imex:IM-27675	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596734|imex:IM-27675-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	-	-	-	figure legend:1B, 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).")	-	2020/01/09	2020/05/11	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rigid:Sl+rIX4CWDdXQmxKOJghzo8j9u4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04114	uniprotkb:P11021	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Rutledge et al. (2009)	pubmed:19164805|imex:IM-27675	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596734|imex:IM-27675-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	-	-	-	figure legend:1B, 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).")	-	2020/01/09	2020/05/11	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rigid:Sl+rIX4CWDdXQmxKOJghzo8j9u4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04114	uniprotkb:P55072	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Rutledge et al. (2009)	pubmed:19164805|imex:IM-27675	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596734|imex:IM-27675-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N	-	-	-	figure legend:1B, 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).")	-	2020/01/09	2020/05/11	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:Sl+rIX4CWDdXQmxKOJghzo8j9u4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04114	uniprotkb:Q01853	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	intact:EBI-80597|ensembl:ENSMUSP00000030164|uniprotkb:Q3TFH9|uniprotkb:Q3TIM2|uniprotkb:Q3TXN9|uniprotkb:Q6PI18|uniprotkb:Q8BSR6|uniprotkb:Q8CEG4	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:tera_mouse(display_long)|uniprotkb:Vcp(gene name)|psi-mi:Vcp(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Rutledge et al. (2009)	pubmed:19164805|imex:IM-27675	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25412560|imex:IM-27675-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N	go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:Q01853|rcsb pdb:1E32|rcsb pdb:1R7R|rcsb pdb:1S3S|rcsb pdb:2PJH|rcsb pdb:3CF0|rcsb pdb:3CF1|rcsb pdb:3CF2|rcsb pdb:3CF3|reactome:R-MMU-110320|reactome:R-MMU-3371511|reactome:R-MMU-382556|reactome:R-MMU-532668|reactome:R-MMU-5358346|reactome:R-MMU-5689877|reactome:R-MMU-5689896|reactome:R-MMU-6798695|reactome:R-MMU-8876725|reactome:R-MMU-9013407|ensembl:ENSMUSG00000028452(gene)|ensembl:ENSMUST00000030164(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0019904"(protein domain specific binding)|refseq:NP_033529.3|dip:DIP-29796N	-	-	-	figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hep2)|taxid:9606(Homo sapiens)	-	2020/01/09	2020/05/11	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs10090	rigid:5WlaPU6wUpdb0NLJNOeTp8VHINE	false	-	his tag:?-?|mutation with no effect:524-524|mutation with no effect:305-305,578-578	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04114	intact:EBI-25412546	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	-	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:tera_chlae_protein(display_short)|psi-mi:EBI-25412546(display_long)	psi-mi:"MI:0030"(cross-linking study)	Rutledge et al. (2009)	pubmed:19164805|imex:IM-27675	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596725|imex:IM-27675-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N	-	-	-	comment:similar to P55072	figure legend:2-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2020/01/09	2020/05/11	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	-	-	false	mutation:2180-2180|sufficient binding region:1-3285..3285	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04114	intact:EBI-25412519	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	-	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:chlae_bip_protein(display_short)|psi-mi:EBI-25412519(display_long)	psi-mi:"MI:0030"(cross-linking study)	Rutledge et al. (2009)	pubmed:19164805|imex:IM-27675	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596725|imex:IM-27675-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N	-	-	-	comment:"similar to P11021 (BIP_HUMAN)"	figure legend:2-3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2020/01/09	2020/05/11	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	-	-	false	mutation:2180-2180|sufficient binding region:1-3285..3285	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-25412519	uniprotkb:P04114	-	intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242	psi-mi:chlae_bip_protein(display_short)|psi-mi:EBI-25412519(display_long)	psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:"MI:0030"(cross-linking study)	Rutledge et al. (2009)	pubmed:19164805|imex:IM-27675	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596715|imex:IM-27675-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N	-	comment:"similar to P11021 (BIP_HUMAN)"	-	figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2020/01/09	2020/05/11	-	rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606	-	false	-	sufficient binding region:1-1323..1323	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-25412519	uniprotkb:P04114-PRO_0000020751	-	intact:EBI-25412533	psi-mi:chlae_bip_protein(display_short)|psi-mi:EBI-25412519(display_long)	psi-mi:p04114-pro_0000020751(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short)	psi-mi:"MI:0030"(cross-linking study)	Rutledge et al. (2009)	pubmed:19164805|imex:IM-27675	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596721|imex:IM-27675-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	-	intact:EBI-3926040(chain-parent)	-	comment:"similar to P11021 (BIP_HUMAN)"	chain-seq-start:28|chain-seq-end:2179	figure legend:2-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2020/01/09	2020/05/11	-	rogid:wy0BdfwQZbtu0F0qGzMiCX1GYBk9606	-	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)