#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9P278 uniprotkb:P54619 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-1181439|ensembl:ENSP00000447433|uniprotkb:B4DDT7|uniprotkb:Q8N7V9 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:aakg1_human(display_long)|uniprotkb:PRKAG1(gene name)|psi-mi:PRKAG1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361352|imex:IM-28429-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 refseq:NP_001193638.1|refseq:NP_001193639.1|refseq:NP_002724.1|refseq:XP_011536864.1|reactome:R-HSA-9619483|reactome:R-HSA-9613354|ensembl:ENSG00000181929(gene)|ensembl:ENST00000548065(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043531"(ADP binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051170"(import into nucleus)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR039166|mint:P54619|rcsb pdb:2UV4|rcsb pdb:2UV5|rcsb pdb:2UV6|rcsb pdb:2UV7|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|refseq:XP_006719562.1|dip:DIP-39974N - comment:mint - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:JNBzPdCbcgr37RKb2sk6yVL+7649606 rigid:kr16TppH1dqX0CTqCsZqdLpcp1E false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P278 uniprotkb:Q9Y478 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-719769|uniprotkb:Q9UBV0|uniprotkb:Q9UE20|uniprotkb:Q9UEX2|uniprotkb:Q9Y6V8|ensembl:ENSP00000229328|ensembl:ENSP00000441369 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:aakb1_human(display_long)|uniprotkb:PRKAB1(gene name)|psi-mi:PRKAB1(display_short)|uniprotkb:AMPK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361352|imex:IM-28429-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 refseq:NP_006244.2|ensembl:ENSG00000111725(gene)|ensembl:ENST00000229328(transcript)|ensembl:ENST00000541640(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0035878"(nail development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0080090"(regulation of primary metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006828(5-AMP-activated protein kinase, beta subunit, complex-interacting region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032640|interpro:IPR037256|interpro:IPR039160|mint:Q9Y478|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|go:"GO:0005654"(nucleoplasm)|refseq:XP_005253966.1|dip:DIP-39736N - comment:mint - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:QJftPEDhjfudQn6uXn5nWOkchc09606 rigid:kr16TppH1dqX0CTqCsZqdLpcp1E false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P278 uniprotkb:Q13131 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-1181405|uniprotkb:O00286|uniprotkb:Q5D0E1|uniprotkb:Q9UNQ4|uniprotkb:Q86VS1|intact:EBI-1383523|uniprotkb:A8MTQ6|uniprotkb:B2R7E1|ensembl:ENSP00000380317 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:aapk1_human(display_long)|uniprotkb:PRKAA1(gene name)|psi-mi:PRKAA1(display_short)|uniprotkb:AMPK1(gene name synonym)|uniprotkb:Tau-protein kinase PRKAA1(gene name synonym)|uniprotkb:Acetyl-CoA carboxylase kinase(gene name synonym)|uniprotkb:Hydroxymethylglutaryl-CoA reductase kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361352|imex:IM-28429-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 refseq:NP_006242.5|refseq:NP_996790.3|ensembl:ENSG00000132356(gene)|ensembl:ENST00000397128(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003682"(chromatin binding)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009411"(response to UV)|go:"GO:0009631"(cold acclimation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031000"(response to caffeine)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046318"(negative regulation of glucosylceramide biosynthetic process)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0047322"("[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity")|go:"GO:0048156"(tau protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050405"([acetyl-CoA carboxylase] kinase activity)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0004672"(protein kinase activity)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061744"(motor behavior)|go:"GO:0061762"(CAMKK-AMPK signaling cascade)|go:"GO:0062028"(regulation of stress granule assembly)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120188"(regulation of bile acid secretion)|go:"GO:1901563"(response to camptothecin)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|go:"GO:1904486"(response to 17alpha-ethynylestradiol)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR028797|interpro:IPR032270|interpro:IPR039137|mint:Q13131|rcsb pdb:4RED|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:5EZV|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1632852|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9619483|dip:DIP-39973N - comment:mint - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:isWWA5k0AqbXwXq5Bj+pk0joegU9606 rigid:kr16TppH1dqX0CTqCsZqdLpcp1E false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P278 uniprotkb:Q8NFG4 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2970160|ensembl:ENSP00000285071|uniprotkb:Q96BD2|uniprotkb:Q96BE4|uniprotkb:A6NJJ8|uniprotkb:Q6ZRX1 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:flcn_human(display_long)|uniprotkb:FLCN(gene name)|psi-mi:FLCN(display_short)|uniprotkb:BHD(gene name synonym)|uniprotkb:BHD skin lesion fibrofolliculoma protein(gene name synonym)|uniprotkb:Birt-Hogg-Dube syndrome protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361352|imex:IM-28429-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097009"(energy homeostasis)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901723"(negative regulation of cell proliferation involved in kidney development)|go:"GO:1903444"(negative regulation of brown fat cell differentiation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2000973"(regulation of pro-B cell differentiation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR021713|interpro:IPR032035|interpro:IPR037520|interpro:IPR037521|interpro:IPR044886|rcsb pdb:3V42|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288|ensembl:ENSG00000154803(gene)|ensembl:ENST00000285071(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|refseq:NP_653207.1|refseq:NP_659434.2|refseq:XP_016879795.1|refseq:XP_016879796.1|refseq:XP_016879797.1|dip:DIP-61287N - comment:mint - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:gd59RCSQ6ssRdb2wz+HZl1V5wLY9606 rigid:kr16TppH1dqX0CTqCsZqdLpcp1E false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P278 uniprotkb:Q13131 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-1181405|uniprotkb:O00286|uniprotkb:Q5D0E1|uniprotkb:Q9UNQ4|uniprotkb:Q86VS1|intact:EBI-1383523|uniprotkb:A8MTQ6|uniprotkb:B2R7E1|ensembl:ENSP00000380317 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:aapk1_human(display_long)|uniprotkb:PRKAA1(gene name)|psi-mi:PRKAA1(display_short)|uniprotkb:AMPK1(gene name synonym)|uniprotkb:Tau-protein kinase PRKAA1(gene name synonym)|uniprotkb:Acetyl-CoA carboxylase kinase(gene name synonym)|uniprotkb:Hydroxymethylglutaryl-CoA reductase kinase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361490|imex:IM-28429-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 refseq:NP_006242.5|refseq:NP_996790.3|ensembl:ENSG00000132356(gene)|ensembl:ENST00000397128(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003682"(chromatin binding)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009411"(response to UV)|go:"GO:0009631"(cold acclimation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031000"(response to caffeine)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046318"(negative regulation of glucosylceramide biosynthetic process)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0047322"("[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity")|go:"GO:0048156"(tau protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050405"([acetyl-CoA carboxylase] kinase activity)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0004672"(protein kinase activity)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061744"(motor behavior)|go:"GO:0061762"(CAMKK-AMPK signaling cascade)|go:"GO:0062028"(regulation of stress granule assembly)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120188"(regulation of bile acid secretion)|go:"GO:1901563"(response to camptothecin)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|go:"GO:1904486"(response to 17alpha-ethynylestradiol)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR028797|interpro:IPR032270|interpro:IPR039137|mint:Q13131|rcsb pdb:4RED|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:5EZV|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1632852|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9619483|dip:DIP-39973N - comment:mint - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:isWWA5k0AqbXwXq5Bj+pk0joegU9606 rigid:xrCqLNqdl25Xcqpj/6al2Vhwq2A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P278 uniprotkb:Q8NFG4 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2970160|ensembl:ENSP00000285071|uniprotkb:Q96BD2|uniprotkb:Q96BE4|uniprotkb:A6NJJ8|uniprotkb:Q6ZRX1 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:flcn_human(display_long)|uniprotkb:FLCN(gene name)|psi-mi:FLCN(display_short)|uniprotkb:BHD(gene name synonym)|uniprotkb:BHD skin lesion fibrofolliculoma protein(gene name synonym)|uniprotkb:Birt-Hogg-Dube syndrome protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361490|imex:IM-28429-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097009"(energy homeostasis)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901723"(negative regulation of cell proliferation involved in kidney development)|go:"GO:1903444"(negative regulation of brown fat cell differentiation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2000973"(regulation of pro-B cell differentiation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR021713|interpro:IPR032035|interpro:IPR037520|interpro:IPR037521|interpro:IPR044886|rcsb pdb:3V42|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288|ensembl:ENSG00000154803(gene)|ensembl:ENST00000285071(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|refseq:NP_653207.1|refseq:NP_659434.2|refseq:XP_016879795.1|refseq:XP_016879796.1|refseq:XP_016879797.1|dip:DIP-61287N - comment:mint - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:gd59RCSQ6ssRdb2wz+HZl1V5wLY9606 rigid:xrCqLNqdl25Xcqpj/6al2Vhwq2A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P278 uniprotkb:Q8NFG4 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2970160|ensembl:ENSP00000285071|uniprotkb:Q96BD2|uniprotkb:Q96BE4|uniprotkb:A6NJJ8|uniprotkb:Q6ZRX1 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:flcn_human(display_long)|uniprotkb:FLCN(gene name)|psi-mi:FLCN(display_short)|uniprotkb:BHD(gene name synonym)|uniprotkb:BHD skin lesion fibrofolliculoma protein(gene name synonym)|uniprotkb:Birt-Hogg-Dube syndrome protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361500|imex:IM-28429-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097009"(energy homeostasis)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901723"(negative regulation of cell proliferation involved in kidney development)|go:"GO:1903444"(negative regulation of brown fat cell differentiation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2000973"(regulation of pro-B cell differentiation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR021713|interpro:IPR032035|interpro:IPR037520|interpro:IPR037521|interpro:IPR044886|rcsb pdb:3V42|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288|ensembl:ENSG00000154803(gene)|ensembl:ENST00000285071(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|refseq:NP_653207.1|refseq:NP_659434.2|refseq:XP_016879795.1|refseq:XP_016879796.1|refseq:XP_016879797.1|dip:DIP-61287N - comment:mint - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:gd59RCSQ6ssRdb2wz+HZl1V5wLY9606 rigid:f9S4f+LNo+6b6vAtsIkhBpBrxWg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P278 uniprotkb:Q8TF40 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361736|imex:IM-28429-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N - comment:mint - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rigid:aphSYVbGdZRYfu+uCOePpOo9CVs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P278 uniprotkb:Q8NFG4 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2970160|ensembl:ENSP00000285071|uniprotkb:Q96BD2|uniprotkb:Q96BE4|uniprotkb:A6NJJ8|uniprotkb:Q6ZRX1 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:flcn_human(display_long)|uniprotkb:FLCN(gene name)|psi-mi:FLCN(display_short)|uniprotkb:BHD(gene name synonym)|uniprotkb:BHD skin lesion fibrofolliculoma protein(gene name synonym)|uniprotkb:Birt-Hogg-Dube syndrome protein(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-26361656|imex:IM-28429-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097009"(energy homeostasis)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901723"(negative regulation of cell proliferation involved in kidney development)|go:"GO:1903444"(negative regulation of brown fat cell differentiation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2000973"(regulation of pro-B cell differentiation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR021713|interpro:IPR032035|interpro:IPR037520|interpro:IPR037521|interpro:IPR044886|rcsb pdb:3V42|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288|ensembl:ENSG00000154803(gene)|ensembl:ENST00000285071(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|refseq:NP_653207.1|refseq:NP_659434.2|refseq:XP_016879795.1|refseq:XP_016879796.1|refseq:XP_016879797.1|dip:DIP-61287N go:"GO:0005737"(cytoplasm) comment:mint - figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:gd59RCSQ6ssRdb2wz+HZl1V5wLY9606 rigid:f9S4f+LNo+6b6vAtsIkhBpBrxWg false flag tag:?-? ha tag:?-? - - psi-mi:"MI:1201"(anti-tag immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q9P278 uniprotkb:Q8NFG4 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2970160|ensembl:ENSP00000285071|uniprotkb:Q96BD2|uniprotkb:Q96BE4|uniprotkb:A6NJJ8|uniprotkb:Q6ZRX1 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:flcn_human(display_long)|uniprotkb:FLCN(gene name)|psi-mi:FLCN(display_short)|uniprotkb:BHD(gene name synonym)|uniprotkb:BHD skin lesion fibrofolliculoma protein(gene name synonym)|uniprotkb:Birt-Hogg-Dube syndrome protein(gene name synonym) psi-mi:"MI:0096"(pull down) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361675|imex:IM-28429-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097009"(energy homeostasis)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901723"(negative regulation of cell proliferation involved in kidney development)|go:"GO:1903444"(negative regulation of brown fat cell differentiation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2000973"(regulation of pro-B cell differentiation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR021713|interpro:IPR032035|interpro:IPR037520|interpro:IPR037521|interpro:IPR044886|rcsb pdb:3V42|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288|ensembl:ENSG00000154803(gene)|ensembl:ENST00000285071(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|refseq:NP_653207.1|refseq:NP_659434.2|refseq:XP_016879795.1|refseq:XP_016879796.1|refseq:XP_016879797.1|dip:DIP-61287N - comment:mint - figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:gd59RCSQ6ssRdb2wz+HZl1V5wLY9606 rigid:f9S4f+LNo+6b6vAtsIkhBpBrxWg false 35s radiolabel:?-? glutathione s tranferase tag:?-?|sufficient binding region:345-579(IPR032035)|necessary binding region:517-579 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9P278 uniprotkb:Q8TF40 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:"MI:0096"(pull down) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361740|imex:IM-28429-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N - comment:mint - figure legend:Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rigid:aphSYVbGdZRYfu+uCOePpOo9CVs false 35s radiolabel:?-? glutathione s tranferase tag:?-?|sufficient binding region:1-602(IPR032035)|sufficient binding region:929-1166(IPR028086) - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9P278 uniprotkb:Q8TF40 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361697|imex:IM-28429-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N - comment:mint - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rigid:aphSYVbGdZRYfu+uCOePpOo9CVs false flag tag:?-? v5 tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8TF40 uniprotkb:Q9P278 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361707|imex:IM-28429-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 - - comment:mint figure legend:Fig. 4A|comment:Expression of ficolin is doxycycline-inducible|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/09/25 2020/09/29 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rigid:JrfowNRqp+M4Tzz5mMPy7W14Rco false v5 tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8TF40 uniprotkb:Q8NFG4 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 intact:EBI-2970160|ensembl:ENSP00000285071|uniprotkb:Q96BD2|uniprotkb:Q96BE4|uniprotkb:A6NJJ8|uniprotkb:Q6ZRX1 psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:flcn_human(display_long)|uniprotkb:FLCN(gene name)|psi-mi:FLCN(display_short)|uniprotkb:BHD(gene name synonym)|uniprotkb:BHD skin lesion fibrofolliculoma protein(gene name synonym)|uniprotkb:Birt-Hogg-Dube syndrome protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361707|imex:IM-28429-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097009"(energy homeostasis)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901723"(negative regulation of cell proliferation involved in kidney development)|go:"GO:1903444"(negative regulation of brown fat cell differentiation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2000973"(regulation of pro-B cell differentiation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR021713|interpro:IPR032035|interpro:IPR037520|interpro:IPR037521|interpro:IPR044886|rcsb pdb:3V42|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288|ensembl:ENSG00000154803(gene)|ensembl:ENST00000285071(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|refseq:NP_653207.1|refseq:NP_659434.2|refseq:XP_016879795.1|refseq:XP_016879796.1|refseq:XP_016879797.1|dip:DIP-61287N - - - figure legend:Fig. 4A|comment:Expression of ficolin is doxycycline-inducible|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/09/25 2020/09/29 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rogid:gd59RCSQ6ssRdb2wz+HZl1V5wLY9606 rigid:JrfowNRqp+M4Tzz5mMPy7W14Rco false v5 tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P278 uniprotkb:Q8TF40 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361716|imex:IM-28429-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N - comment:mint - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rigid:aphSYVbGdZRYfu+uCOePpOo9CVs false flag tag:?-? v5 tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P278 uniprotkb:Q8NFG4 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2970160|ensembl:ENSP00000285071|uniprotkb:Q96BD2|uniprotkb:Q96BE4|uniprotkb:A6NJJ8|uniprotkb:Q6ZRX1 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:flcn_human(display_long)|uniprotkb:FLCN(gene name)|psi-mi:FLCN(display_short)|uniprotkb:BHD(gene name synonym)|uniprotkb:BHD skin lesion fibrofolliculoma protein(gene name synonym)|uniprotkb:Birt-Hogg-Dube syndrome protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361724|imex:IM-28429-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097009"(energy homeostasis)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901723"(negative regulation of cell proliferation involved in kidney development)|go:"GO:1903444"(negative regulation of brown fat cell differentiation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2000973"(regulation of pro-B cell differentiation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR021713|interpro:IPR032035|interpro:IPR037520|interpro:IPR037521|interpro:IPR044886|rcsb pdb:3V42|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288|ensembl:ENSG00000154803(gene)|ensembl:ENST00000285071(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|refseq:NP_653207.1|refseq:NP_659434.2|refseq:XP_016879795.1|refseq:XP_016879796.1|refseq:XP_016879797.1|dip:DIP-61287N - comment:mint - figure legend:Fig. 4A|comment:Expression of ficolon is doxycycline-inducible|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:gd59RCSQ6ssRdb2wz+HZl1V5wLY9606 rigid:JrfowNRqp+M4Tzz5mMPy7W14Rco false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P278 uniprotkb:Q8TF40 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361724|imex:IM-28429-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N - comment:mint - figure legend:Fig. 4A|comment:Expression of ficolon is doxycycline-inducible|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rigid:JrfowNRqp+M4Tzz5mMPy7W14Rco false flag tag:?-? v5 tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8TF40 uniprotkb:P54619 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 intact:EBI-1181439|ensembl:ENSP00000447433|uniprotkb:B4DDT7|uniprotkb:Q8N7V9 psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:aakg1_human(display_long)|uniprotkb:PRKAG1(gene name)|psi-mi:PRKAG1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361869|imex:IM-28429-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N refseq:NP_001193638.1|refseq:NP_001193639.1|refseq:NP_002724.1|refseq:XP_011536864.1|reactome:R-HSA-9619483|reactome:R-HSA-9613354|ensembl:ENSG00000181929(gene)|ensembl:ENST00000548065(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043531"(ADP binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051170"(import into nucleus)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR039166|mint:P54619|rcsb pdb:2UV4|rcsb pdb:2UV5|rcsb pdb:2UV6|rcsb pdb:2UV7|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|refseq:XP_006719562.1|dip:DIP-39974N - - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rogid:JNBzPdCbcgr37RKb2sk6yVL+7649606 rigid:EOPYtLZl0o42VwQOZ/+0atzSWAQ false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TF40 uniprotkb:Q8TF40 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361869|imex:IM-28429-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N - - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rigid:EOPYtLZl0o42VwQOZ/+0atzSWAQ false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TF40 uniprotkb:Q8NFG4 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 intact:EBI-2970160|ensembl:ENSP00000285071|uniprotkb:Q96BD2|uniprotkb:Q96BE4|uniprotkb:A6NJJ8|uniprotkb:Q6ZRX1 psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:flcn_human(display_long)|uniprotkb:FLCN(gene name)|psi-mi:FLCN(display_short)|uniprotkb:BHD(gene name synonym)|uniprotkb:BHD skin lesion fibrofolliculoma protein(gene name synonym)|uniprotkb:Birt-Hogg-Dube syndrome protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361869|imex:IM-28429-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097009"(energy homeostasis)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901723"(negative regulation of cell proliferation involved in kidney development)|go:"GO:1903444"(negative regulation of brown fat cell differentiation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2000973"(regulation of pro-B cell differentiation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR021713|interpro:IPR032035|interpro:IPR037520|interpro:IPR037521|interpro:IPR044886|rcsb pdb:3V42|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288|ensembl:ENSG00000154803(gene)|ensembl:ENST00000285071(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|refseq:NP_653207.1|refseq:NP_659434.2|refseq:XP_016879795.1|refseq:XP_016879796.1|refseq:XP_016879797.1|dip:DIP-61287N - - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rogid:gd59RCSQ6ssRdb2wz+HZl1V5wLY9606 rigid:EOPYtLZl0o42VwQOZ/+0atzSWAQ false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TF40 uniprotkb:Q9P278 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361881|imex:IM-28429-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 - - comment:mint figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rigid:Jk4WJ6mQxWgOtHmAPDoNNHq3g4I false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TF40 uniprotkb:P54619 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 intact:EBI-1181439|ensembl:ENSP00000447433|uniprotkb:B4DDT7|uniprotkb:Q8N7V9 psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:aakg1_human(display_long)|uniprotkb:PRKAG1(gene name)|psi-mi:PRKAG1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361881|imex:IM-28429-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N refseq:NP_001193638.1|refseq:NP_001193639.1|refseq:NP_002724.1|refseq:XP_011536864.1|reactome:R-HSA-9619483|reactome:R-HSA-9613354|ensembl:ENSG00000181929(gene)|ensembl:ENST00000548065(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043531"(ADP binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051170"(import into nucleus)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR039166|mint:P54619|rcsb pdb:2UV4|rcsb pdb:2UV5|rcsb pdb:2UV6|rcsb pdb:2UV7|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|refseq:XP_006719562.1|dip:DIP-39974N - - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rogid:JNBzPdCbcgr37RKb2sk6yVL+7649606 rigid:Jk4WJ6mQxWgOtHmAPDoNNHq3g4I false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8TF40 uniprotkb:Q8NFG4 intact:EBI-2946919|ensembl:ENSP00000421985|uniprotkb:Q9BUT0|uniprotkb:Q86T47|uniprotkb:D6RJH5 intact:EBI-2970160|ensembl:ENSP00000285071|uniprotkb:Q96BD2|uniprotkb:Q96BE4|uniprotkb:A6NJJ8|uniprotkb:Q6ZRX1 psi-mi:fnip1_human(display_long)|uniprotkb:FNIP1(gene name)|psi-mi:FNIP1(display_short)|uniprotkb:KIAA1961(gene name synonym) psi-mi:flcn_human(display_long)|uniprotkb:FLCN(gene name)|psi-mi:FLCN(display_short)|uniprotkb:BHD(gene name synonym)|uniprotkb:BHD skin lesion fibrofolliculoma protein(gene name synonym)|uniprotkb:Birt-Hogg-Dube syndrome protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361881|imex:IM-28429-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000217128(gene)|ensembl:ENST00000510461(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051087"(chaperone binding)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q8TF40|reactome:R-HSA-9639288|go:"GO:0032008"(positive regulation of TOR signaling)|refseq:NP_001008738.2|refseq:NP_588613.2|refseq:NP_001333042.1|dip:DIP-57169N go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097009"(energy homeostasis)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901723"(negative regulation of cell proliferation involved in kidney development)|go:"GO:1903444"(negative regulation of brown fat cell differentiation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2000973"(regulation of pro-B cell differentiation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR021713|interpro:IPR032035|interpro:IPR037520|interpro:IPR037521|interpro:IPR044886|rcsb pdb:3V42|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288|ensembl:ENSG00000154803(gene)|ensembl:ENST00000285071(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|refseq:NP_653207.1|refseq:NP_659434.2|refseq:XP_016879795.1|refseq:XP_016879796.1|refseq:XP_016879797.1|dip:DIP-61287N - - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:HVA3rKbb8nS/97UCKVDCje0xTjw9606 rogid:gd59RCSQ6ssRdb2wz+HZl1V5wLY9606 rigid:Jk4WJ6mQxWgOtHmAPDoNNHq3g4I false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P278 uniprotkb:Q9P278 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361891|imex:IM-28429-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 - comment:mint comment:mint figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rigid:A5iR1nIAtJ5XXFlBrIuRIUVgvkc false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P278 uniprotkb:P54619 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-1181439|ensembl:ENSP00000447433|uniprotkb:B4DDT7|uniprotkb:Q8N7V9 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:aakg1_human(display_long)|uniprotkb:PRKAG1(gene name)|psi-mi:PRKAG1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361891|imex:IM-28429-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 refseq:NP_001193638.1|refseq:NP_001193639.1|refseq:NP_002724.1|refseq:XP_011536864.1|reactome:R-HSA-9619483|reactome:R-HSA-9613354|ensembl:ENSG00000181929(gene)|ensembl:ENST00000548065(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043531"(ADP binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051170"(import into nucleus)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR039166|mint:P54619|rcsb pdb:2UV4|rcsb pdb:2UV5|rcsb pdb:2UV6|rcsb pdb:2UV7|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|refseq:XP_006719562.1|dip:DIP-39974N - comment:mint - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:JNBzPdCbcgr37RKb2sk6yVL+7649606 rigid:A5iR1nIAtJ5XXFlBrIuRIUVgvkc false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9P278 uniprotkb:Q8NFG4 intact:EBI-7597109|intact:MINT-7298240|uniprotkb:Q05DC3|uniprotkb:Q9H994|uniprotkb:Q96I31|ensembl:ENSP00000264433 intact:EBI-2970160|ensembl:ENSP00000285071|uniprotkb:Q96BD2|uniprotkb:Q96BE4|uniprotkb:A6NJJ8|uniprotkb:Q6ZRX1 psi-mi:fnip2_human(display_long)|uniprotkb:O6-methylguanine-induced apoptosis 1 protein(gene name synonym)|uniprotkb:FNIPL(gene name synonym)|uniprotkb:MAPO1(gene name synonym)|uniprotkb:FNIP2(gene name)|psi-mi:FNIP2(display_short)|uniprotkb:KIAA1450(gene name synonym)|uniprotkb:FNIP1-like protein(gene name synonym) psi-mi:flcn_human(display_long)|uniprotkb:FLCN(gene name)|psi-mi:FLCN(display_short)|uniprotkb:BHD(gene name synonym)|uniprotkb:BHD skin lesion fibrofolliculoma protein(gene name synonym)|uniprotkb:Birt-Hogg-Dube syndrome protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasumi et al. (2008) pubmed:18403135|imex:IM-28429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26361891|imex:IM-28429-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310845.1|refseq:NP_001332972.1|refseq:NP_065891.1|ensembl:ENSG00000052795(gene)|ensembl:ENST00000264433(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051087"(chaperone binding)|interpro:IPR026156|interpro:IPR028084|interpro:IPR028085|interpro:IPR028086|interpro:IPR037545|mint:Q9P278|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288 go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032418"(lysosome localization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097009"(energy homeostasis)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901723"(negative regulation of cell proliferation involved in kidney development)|go:"GO:1903444"(negative regulation of brown fat cell differentiation)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:2000973"(regulation of pro-B cell differentiation)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR021713|interpro:IPR032035|interpro:IPR037520|interpro:IPR037521|interpro:IPR044886|rcsb pdb:3V42|rcsb pdb:6NZD|rcsb pdb:6ULG|reactome:R-HSA-9639288|ensembl:ENSG00000154803(gene)|ensembl:ENST00000285071(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|refseq:NP_653207.1|refseq:NP_659434.2|refseq:XP_016879795.1|refseq:XP_016879796.1|refseq:XP_016879797.1|dip:DIP-61287N - comment:mint - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/09/25 2020/09/29 rogid:hdSPB5yh7jtlmQogUtH8Lkjhs5k9606 rogid:gd59RCSQ6ssRdb2wz+HZl1V5wLY9606 rigid:A5iR1nIAtJ5XXFlBrIuRIUVgvkc false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)