#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q13424	uniprotkb:B7UR60	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26377591|imex:IM-28455-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/21	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:P+G3Aria4ASXYXpH49TridDfhSQ	false	binding-associated region:79-300	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NUP9	uniprotkb:B7UR60	intact:EBI-1171517|ensembl:ENSP00000278193	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26377624|imex:IM-28455-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060832.1|ensembl:ENSG00000148943(gene)|ensembl:ENST00000278193(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|interpro:IPR001478(PDZ/DHR/GLGF)	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/21	rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:nIKdSbFKriUtE/Yq4PRiT1L/9vo	false	binding-associated region:1-194	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5EBL8	uniprotkb:B7UR60	intact:EBI-1644207|uniprotkb:Q6UWE1|uniprotkb:Q9P0Q1|uniprotkb:D3DVU3|ensembl:ENSP00000239666|ensembl:ENSP00000363578	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:pdz11_human(display_long)|uniprotkb:PDZD11(gene name)|psi-mi:PDZD11(display_short)|uniprotkb:PDZK11(gene name synonym)|uniprotkb:AIPP1(gene name synonym)|uniprotkb:ATPase-interacting PDZ protein(gene name synonym)|uniprotkb:PISP(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase-interacting single-PDZ protein(gene name synonym)|uniprotkb:HSPC227(orf name)|uniprotkb:UNQ6486/PRO21335(orf name)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26377632|imex:IM-28455-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011529275.1|refseq:NP_057568.1|refseq:XP_016885057.1|ensembl:ENSG00000120509(gene)|ensembl:ENST00000239666(transcript)|ensembl:ENST00000374454(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0098793"(presynapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q5EBL8|reactome:R-HSA-196780|reactome:R-HSA-199220|reactome:R-HSA-425397|reactome:R-HSA-6803544|reactome:R-HSA-936837|interpro:IPR001478(PDZ/DHR/GLGF)	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/21	rogid:lbIwGsi2cawUe/V0/Km+ek9pOIE9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:no3JaFTsH48zrfgkdarRkH190Ig	false	binding-associated region:1-139	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96L92	uniprotkb:B7UR60	intact:EBI-2514865|ensembl:ENSP00000400333|uniprotkb:Q9H3K8|uniprotkb:Q4AEJ5|uniprotkb:Q5VWB0|uniprotkb:Q5VWB2|uniprotkb:Q96D79|uniprotkb:Q5VWB1|uniprotkb:Q32Q36|uniprotkb:Q6IPP6|uniprotkb:Q86UB1	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:snx27_human(display_long)|uniprotkb:SNX27(gene name)|psi-mi:SNX27(display_short)|uniprotkb:KIAA0488(gene name synonym)|uniprotkb:My014(orf name)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26377638|imex:IM-28455-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143376(gene)|ensembl:ENST00000458013(transcript)|go:"GO:0001770"(establishment of natural killer cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007165"(signal transduction)|refseq:NP_001317652.1|refseq:NP_112180.4|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR000159(Ras-association)|interpro:IPR001683(Phox-like)|interpro:IPR028667|interpro:IPR029071|interpro:IPR036034|interpro:IPR036871|interpro:IPR037827|interpro:IPR037831|interpro:IPR037833|interpro:IPR037835|mint:Q96L92|rcsb pdb:4HAS|rcsb pdb:5ZN9|rcsb pdb:6SAK|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001478(PDZ/DHR/GLGF)	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/21	rogid:UsAQwtTpOo87fFo6fQJNAZxrFe09606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:CIyUYldJHdhHRXd6rTNXEK2x85A	false	binding-associated region:56-167	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95487	uniprotkb:B7UR60	intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26377646|imex:IM-28455-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802(gene)|ensembl:ENST00000265175(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090178"(regulation of establishment of planar polarity involved in neural tube closure)|go:"GO:1901301"(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|rcsb pdb:3EH1|go:"GO:0021747"(cochlear nucleus development)|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829|refseq:NP_001305014.1|refseq:NP_001305015.1|refseq:NP_001287742.1|interpro:IPR001478(PDZ/DHR/GLGF)	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/21	rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:UKgj27WJYDVLh13UDAp2rsO6fio	false	binding-associated region:67-292	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13428	uniprotkb:B7UR60	intact:EBI-396105|uniprotkb:Q6SC72|uniprotkb:Q7Z5W9|uniprotkb:Q96A52|uniprotkb:Q99408|uniprotkb:Q99860|uniprotkb:A0JLU0|uniprotkb:B4E111|intact:EBI-28974716|ensembl:ENSP00000367028|ensembl:ENSP00000421655	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:tcof_human(display_long)|uniprotkb:TCOF1(gene name)|psi-mi:TCOF1(display_short)|uniprotkb:Treacher Collins syndrome protein(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0398"(two hybrid pooling approach)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26377654|imex:IM-28455-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000347.2|refseq:NP_001008657.1|refseq:NP_001128715.1|refseq:NP_001128716.1|refseq:NP_001128717.1|refseq:NP_001182070.1|ensembl:ENST00000323668|ensembl:ENSP00000325223|ensembl:ENSP00000367028|ensembl:ENST00000394269|ensembl:ENSP00000377811|ensembl:ENST00000427724|ensembl:ENSP00000390717|ensembl:ENST00000439160|ensembl:ENSP00000406888|ensembl:ENST00000445265|ensembl:ENSP00000409944|ensembl:ENSP00000421655|ensembl:ENST00000643257|ensembl:ENSP00000493815|refseq:XP_005268562.1|ensembl:ENSG00000070814(gene)|ensembl:ENST00000377797(transcript)|ensembl:ENST00000504761(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003993(Treacher Collins syndrome, treacle)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR017859|mint:Q13428|dip:DIP-32953N|interpro:IPR001478(PDZ/DHR/GLGF)	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:table 1|comment:To identify potential eukaryotic interacting partners of  EspI, we performed a Y2HS screen of a pretransformed  HeLa cDNA library using the full-length EspI from EPEC  E2348/69 as bait.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/21	rogid:eRazgHpn5CwQVFH5hRnA/sVp24M9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:XgON+FSIMEMDf7J15OYZfImFjR4	false	binding-associated region:356-513	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q13424	uniprotkb:B7UR60	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26378057|imex:IM-28455-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig.1a, fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/26	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:P+G3Aria4ASXYXpH49TridDfhSQ	false	-	necessary binding region:434-440|mutation disrupting interaction:437-437,440-440	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O95487	uniprotkb:B7UR60	intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429143|imex:IM-28455-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802(gene)|ensembl:ENST00000265175(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090178"(regulation of establishment of planar polarity involved in neural tube closure)|go:"GO:1901301"(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|rcsb pdb:3EH1|go:"GO:0021747"(cochlear nucleus development)|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829|refseq:NP_001305014.1|refseq:NP_001305015.1|refseq:NP_001287742.1	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig.1a, fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/26	rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:UKgj27WJYDVLh13UDAp2rsO6fio	false	-	necessary binding region:434-440|mutation disrupting interaction:437-437,440-440	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13428	uniprotkb:B7UR60	intact:EBI-396105|uniprotkb:Q6SC72|uniprotkb:Q7Z5W9|uniprotkb:Q96A52|uniprotkb:Q99408|uniprotkb:Q99860|uniprotkb:A0JLU0|uniprotkb:B4E111|intact:EBI-28974716|ensembl:ENSP00000367028|ensembl:ENSP00000421655	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:tcof_human(display_long)|uniprotkb:TCOF1(gene name)|psi-mi:TCOF1(display_short)|uniprotkb:Treacher Collins syndrome protein(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429152|imex:IM-28455-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000347.2|refseq:NP_001008657.1|refseq:NP_001128715.1|refseq:NP_001128716.1|refseq:NP_001128717.1|refseq:NP_001182070.1|ensembl:ENST00000323668|ensembl:ENSP00000325223|ensembl:ENSP00000367028|ensembl:ENST00000394269|ensembl:ENSP00000377811|ensembl:ENST00000427724|ensembl:ENSP00000390717|ensembl:ENST00000439160|ensembl:ENSP00000406888|ensembl:ENST00000445265|ensembl:ENSP00000409944|ensembl:ENSP00000421655|ensembl:ENST00000643257|ensembl:ENSP00000493815|refseq:XP_005268562.1|ensembl:ENSG00000070814(gene)|ensembl:ENST00000377797(transcript)|ensembl:ENST00000504761(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003993(Treacher Collins syndrome, treacle)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR017859|mint:Q13428|dip:DIP-32953N	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig.1a, fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/26	rogid:eRazgHpn5CwQVFH5hRnA/sVp24M9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:XgON+FSIMEMDf7J15OYZfImFjR4	false	-	mutation with no effect:437-437,440-440	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B7UR60	uniprotkb:Q5EBL8	intact:EBI-25435618|ensemblbacteria:CAS08990	intact:EBI-1644207|uniprotkb:Q6UWE1|uniprotkb:Q9P0Q1|uniprotkb:D3DVU3|ensembl:ENSP00000239666|ensembl:ENSP00000363578	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:pdz11_human(display_long)|uniprotkb:PDZD11(gene name)|psi-mi:PDZD11(display_short)|uniprotkb:PDZK11(gene name synonym)|uniprotkb:AIPP1(gene name synonym)|uniprotkb:ATPase-interacting PDZ protein(gene name synonym)|uniprotkb:PISP(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase-interacting single-PDZ protein(gene name synonym)|uniprotkb:HSPC227(orf name)|uniprotkb:UNQ6486/PRO21335(orf name)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429175|imex:IM-28455-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	refseq:XP_011529275.1|refseq:NP_057568.1|refseq:XP_016885057.1|ensembl:ENSG00000120509(gene)|ensembl:ENST00000239666(transcript)|ensembl:ENST00000374454(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0098793"(presynapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q5EBL8|reactome:R-HSA-196780|reactome:R-HSA-199220|reactome:R-HSA-425397|reactome:R-HSA-6803544|reactome:R-HSA-936837	-	-	-	figure legend:fig.1a, fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/26	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:lbIwGsi2cawUe/V0/Km+ek9pOIE9606	rigid:no3JaFTsH48zrfgkdarRkH190Ig	false	mutation disrupting interaction:437-437,440-440|necessary binding region:434-440	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B7UR60	uniprotkb:Q9NUP9	intact:EBI-25435618|ensemblbacteria:CAS08990	intact:EBI-1171517|ensembl:ENSP00000278193	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429184|imex:IM-28455-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	refseq:NP_060832.1|ensembl:ENSG00000148943(gene)|ensembl:ENST00000278193(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736	-	-	-	figure legend:fig.1a, fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/26	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606	rigid:nIKdSbFKriUtE/Yq4PRiT1L/9vo	false	mutation disrupting interaction:437-437,440-440|necessary binding region:434-440	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:B7UR60	uniprotkb:Q96L92	intact:EBI-25435618|ensemblbacteria:CAS08990	intact:EBI-2514865|ensembl:ENSP00000400333|uniprotkb:Q9H3K8|uniprotkb:Q4AEJ5|uniprotkb:Q5VWB0|uniprotkb:Q5VWB2|uniprotkb:Q96D79|uniprotkb:Q5VWB1|uniprotkb:Q32Q36|uniprotkb:Q6IPP6|uniprotkb:Q86UB1	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:snx27_human(display_long)|uniprotkb:SNX27(gene name)|psi-mi:SNX27(display_short)|uniprotkb:KIAA0488(gene name synonym)|uniprotkb:My014(orf name)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429193|imex:IM-28455-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	ensembl:ENSG00000143376(gene)|ensembl:ENST00000458013(transcript)|go:"GO:0001770"(establishment of natural killer cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007165"(signal transduction)|refseq:NP_001317652.1|refseq:NP_112180.4|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR000159(Ras-association)|interpro:IPR001683(Phox-like)|interpro:IPR028667|interpro:IPR029071|interpro:IPR036034|interpro:IPR036871|interpro:IPR037827|interpro:IPR037831|interpro:IPR037833|interpro:IPR037835|mint:Q96L92|rcsb pdb:4HAS|rcsb pdb:5ZN9|rcsb pdb:6SAK|interpro:IPR001478(PDZ/DHR/GLGF)	-	-	-	figure legend:fig.1a, fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/26	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rogid:UsAQwtTpOo87fFo6fQJNAZxrFe09606	rigid:CIyUYldJHdhHRXd6rTNXEK2x85A	false	mutation with no effect:437-437,440-440|necessary binding region:434-440	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:D2TJZ4	uniprotkb:Q9NUP9	intact:EBI-13953726	intact:EBI-1171517|ensembl:ENSP00000278193	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:ROD_03401(locus name)	psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910("Citrobacter rodentium (strain ICC168)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26430129|imex:IM-28455-48	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_012904700.1	refseq:NP_060832.1|ensembl:ENSG00000148943(gene)|ensembl:ENST00000278193(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736	-	-	-	figure legend:fig.6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/28	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606	rigid:0sn2aKxYCjx2Tik9mOmdbj/Cj/k	false	necessary binding region:424-430	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:D2TJZ4	uniprotkb:Q96L92	intact:EBI-13953726	intact:EBI-2514865|ensembl:ENSP00000400333|uniprotkb:Q9H3K8|uniprotkb:Q4AEJ5|uniprotkb:Q5VWB0|uniprotkb:Q5VWB2|uniprotkb:Q96D79|uniprotkb:Q5VWB1|uniprotkb:Q32Q36|uniprotkb:Q6IPP6|uniprotkb:Q86UB1	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:ROD_03401(locus name)	psi-mi:snx27_human(display_long)|uniprotkb:SNX27(gene name)|psi-mi:SNX27(display_short)|uniprotkb:KIAA0488(gene name synonym)|uniprotkb:My014(orf name)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910("Citrobacter rodentium (strain ICC168)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26430138|imex:IM-28455-50	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_012904700.1	ensembl:ENSG00000143376(gene)|ensembl:ENST00000458013(transcript)|go:"GO:0001770"(establishment of natural killer cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007165"(signal transduction)|refseq:NP_001317652.1|refseq:NP_112180.4|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR000159(Ras-association)|interpro:IPR001683(Phox-like)|interpro:IPR028667|interpro:IPR029071|interpro:IPR036034|interpro:IPR036871|interpro:IPR037827|interpro:IPR037831|interpro:IPR037833|interpro:IPR037835|mint:Q96L92|rcsb pdb:4HAS|rcsb pdb:5ZN9|rcsb pdb:6SAK|interpro:IPR001478(PDZ/DHR/GLGF)	-	-	-	figure legend:fig.6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/28	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:UsAQwtTpOo87fFo6fQJNAZxrFe09606	rigid:04LK6xQlkcfp7L2SyKb6qZSeP1Q	false	necessary binding region:424-430	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:D2TJZ4	uniprotkb:Q5EBL8	intact:EBI-13953726	intact:EBI-1644207|uniprotkb:Q6UWE1|uniprotkb:Q9P0Q1|uniprotkb:D3DVU3|ensembl:ENSP00000239666|ensembl:ENSP00000363578	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:ROD_03401(locus name)	psi-mi:pdz11_human(display_long)|uniprotkb:PDZD11(gene name)|psi-mi:PDZD11(display_short)|uniprotkb:PDZK11(gene name synonym)|uniprotkb:AIPP1(gene name synonym)|uniprotkb:ATPase-interacting PDZ protein(gene name synonym)|uniprotkb:PISP(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase-interacting single-PDZ protein(gene name synonym)|uniprotkb:HSPC227(orf name)|uniprotkb:UNQ6486/PRO21335(orf name)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910("Citrobacter rodentium (strain ICC168)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26430144|imex:IM-28455-52	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_012904700.1	refseq:XP_011529275.1|refseq:NP_057568.1|refseq:XP_016885057.1|ensembl:ENSG00000120509(gene)|ensembl:ENST00000239666(transcript)|ensembl:ENST00000374454(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0098793"(presynapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q5EBL8|reactome:R-HSA-196780|reactome:R-HSA-199220|reactome:R-HSA-425397|reactome:R-HSA-6803544|reactome:R-HSA-936837	-	-	-	figure legend:fig.6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/28	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:lbIwGsi2cawUe/V0/Km+ek9pOIE9606	rigid:X9k2a7eiIQi//1tFNusoNVrL7IA	false	necessary binding region:424-430	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:D2TJZ4	uniprotkb:Q13424	intact:EBI-13953726	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:ROD_03401(locus name)	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910("Citrobacter rodentium (strain ICC168)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26430150|imex:IM-28455-54	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_012904700.1	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	-	-	-	figure legend:fig.6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/28	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rigid:SXbyTkqw8yWETa96RTRhm8oFKd0	false	necessary binding region:424-430	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:D2TJZ4	uniprotkb:O95487	intact:EBI-13953726	intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:ROD_03401(locus name)	psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910("Citrobacter rodentium (strain ICC168)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26430156|imex:IM-28455-62	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_012904700.1	refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802(gene)|ensembl:ENST00000265175(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090178"(regulation of establishment of planar polarity involved in neural tube closure)|go:"GO:1901301"(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|rcsb pdb:3EH1|go:"GO:0021747"(cochlear nucleus development)|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829|refseq:NP_001305014.1|refseq:NP_001305015.1|refseq:NP_001287742.1	-	-	-	figure legend:fig.6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/28	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606	rigid:kOtDZ4w6f78PZmD68E2rIhIZ1No	false	necessary binding region:424-430	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:D2TJZ4	uniprotkb:Q13428	intact:EBI-13953726	intact:EBI-396105|uniprotkb:Q6SC72|uniprotkb:Q7Z5W9|uniprotkb:Q96A52|uniprotkb:Q99408|uniprotkb:Q99860|uniprotkb:A0JLU0|uniprotkb:B4E111|intact:EBI-28974716|ensembl:ENSP00000367028|ensembl:ENSP00000421655	psi-mi:d2tjz4_citri(display_long)|uniprotkb:espI(gene name)|psi-mi:espI(display_short)|uniprotkb:ROD_03401(locus name)	psi-mi:tcof_human(display_long)|uniprotkb:TCOF1(gene name)|psi-mi:TCOF1(display_short)|uniprotkb:Treacher Collins syndrome protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:637910(Citrobacter freundii biotype 4280)|taxid:637910("Citrobacter rodentium (strain ICC168)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26430162|imex:IM-28455-56	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_012904700.1	refseq:NP_000347.2|refseq:NP_001008657.1|refseq:NP_001128715.1|refseq:NP_001128716.1|refseq:NP_001128717.1|refseq:NP_001182070.1|ensembl:ENST00000323668|ensembl:ENSP00000325223|ensembl:ENSP00000367028|ensembl:ENST00000394269|ensembl:ENSP00000377811|ensembl:ENST00000427724|ensembl:ENSP00000390717|ensembl:ENST00000439160|ensembl:ENSP00000406888|ensembl:ENST00000445265|ensembl:ENSP00000409944|ensembl:ENSP00000421655|ensembl:ENST00000643257|ensembl:ENSP00000493815|refseq:XP_005268562.1|ensembl:ENSG00000070814(gene)|ensembl:ENST00000377797(transcript)|ensembl:ENST00000504761(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003993(Treacher Collins syndrome, treacle)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR017859|mint:Q13428|dip:DIP-32953N	-	-	-	figure legend:fig.6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/10/13	2020/10/28	rogid:PxNhenqiu0k8rDZhr1zXhKEjTVE637910	rogid:eRazgHpn5CwQVFH5hRnA/sVp24M9606	rigid:OGY5ycjb/8608zeSwL+7HQGXj0Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86UL8	uniprotkb:B7UR60	intact:EBI-311035|uniprotkb:O60434|uniprotkb:O60510|uniprotkb:Q86UI7|uniprotkb:Q9NP44|uniprotkb:Q9UDQ5|uniprotkb:Q9UDU1|uniprotkb:A4D1C1|uniprotkb:A7E2C3|intact:EBI-28973920|ensembl:ENSP00000346151	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:magi2_human(display_long)|uniprotkb:MAGI2(gene name)|psi-mi:MAGI2(display_short)|uniprotkb:KIAA0705(gene name synonym)|uniprotkb:ACVRINP1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein A(gene name synonym)|uniprotkb:AIP1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429242|imex:IM-28455-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000346151|ensembl:ENST00000419488|ensembl:ENSP00000405766|refseq:NP_036433.2|refseq:NP_001288057.1|ensembl:ENSG00000187391(gene)|ensembl:ENST00000354212(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0045202"(synapse)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR030036|interpro:IPR036020|interpro:IPR036034|mint:Q86UL8|rcsb pdb:1UEP|rcsb pdb:1UEQ|rcsb pdb:1UEW|rcsb pdb:1UJV|rcsb pdb:1WFV|reactome:R-HSA-373753|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043113"(receptor clustering)	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:/uTMSMqB1wrlyHj2P9OVVBCpWcY9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:Efgpnx/x/qL8cfcrLXi9Afgr4y8	false	his tag:?-?|binding-associated region:599-743	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5TCQ9	uniprotkb:B7UR60	intact:EBI-310506|uniprotkb:Q5TCR0|uniprotkb:Q9H2V6|uniprotkb:Q5TCQ8|uniprotkb:Q9H5Y8|uniprotkb:Q9HBC4|intact:EBI-2512710|intact:EBI-991068|ensembl:ENSP00000304604|uniprotkb:Q9HCD8|uniprotkb:A0A024R0E9|uniprotkb:A0A024R0H3	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:magi3_human(display_long)|uniprotkb:MAGI3(gene name)|psi-mi:MAGI3(display_short)|uniprotkb:KIAA1634(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 3(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429833|imex:IM-28455-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000307546(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|ensembl:ENSG00000081026(gene)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0030054"(cell junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0016020"(membrane)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR030035|interpro:IPR036020|interpro:IPR036034|mint:Q5TCQ9|rcsb pdb:3SOE|refseq:NP_001136254.1|refseq:NP_690864.2|refseq:XP_005270794.1	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:muK+zH3ww4Ve8aJ74iU2be8hRa09606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:gql4iS+HpNlfXC/jjgafV5k9FDY	false	binding-associated region:429-579|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q28619	uniprotkb:B7UR60	intact:EBI-7073613|intact:MINT-148118	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:nhrf1_rabit(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429845|imex:IM-28455-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR031199|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0030175"(filopodium)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070293"(renal absorption)|go:"GO:0071944"(cell periphery)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:2000146"(negative regulation of cell motility)|refseq:NP_001075814.1|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	function:Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli|comment:mint	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:Whyx53K9mx3z81+1fNi++cEigDc9986	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:htFy6dZGrP9rGSQ29aKYaffs0Mg	false	binding-associated region:1-151|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15599	uniprotkb:B7UR60	intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005|intact:EBI-15579694	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:nhrf2_human(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429856|imex:IM-28455-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|ensembl:ENSG00000065054(gene)|ensembl:ENST00000424542(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031197|interpro:IPR036034|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|go:"GO:0042802"(identical protein binding)|dip:DIP-29093N	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:uta98I2Rt9s9h2ckdisEtP3ay4M	false	binding-associated region:149-337|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P31016	uniprotkb:B7UR60	intact:EBI-375655|uniprotkb:P97631|ensembl:ENSRNOP00000059045	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:dlg4_rat(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)|uniprotkb:Psd95(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429867|imex:IM-28455-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|rcsb pdb:1TP3|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:P31016|rcsb pdb:1BE9|rcsb pdb:1BFE|rcsb pdb:1IU0|rcsb pdb:1IU2|rcsb pdb:1JXM|rcsb pdb:1JXO|rcsb pdb:1KJW|rcsb pdb:1QLC|rcsb pdb:1RGR|rcsb pdb:5MZ7|rcsb pdb:5W72|rcsb pdb:5YPO|rcsb pdb:5YPR|rcsb pdb:7CQF|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5625900|reactome:R-RNO-5673001|reactome:R-RNO-5682910|reactome:R-RNO-6794361|reactome:R-RNO-8849932|rcsb pdb:1TP5|rcsb pdb:1TQ3|rcsb pdb:2KA9|rcsb pdb:2MHO|rcsb pdb:2XKX|rcsb pdb:3GSL|rcsb pdb:3WP0|rcsb pdb:3WP1|rcsb pdb:5B64|rcsb pdb:5D13|rcsb pdb:5GNV|rcsb pdb:5HDY|rcsb pdb:5HEB|rcsb pdb:5HED|rcsb pdb:5HET|rcsb pdb:5HEY|rcsb pdb:5HF1|rcsb pdb:5HF4|rcsb pdb:5HFB|rcsb pdb:5HFC|rcsb pdb:5HFD|rcsb pdb:5HFE|rcsb pdb:5HFF|ensembl:ENSRNOG00000018526(gene)|ensembl:ENSRNOT00000068493(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|rgd:68424|refseq:NP_062567.1|dip:DIP-29264N	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:4oWbxT/HVvWQqdbFqt3htRuQNpw10116	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:f8TwVhFs5SVS9995nh3LhEfZNFY	false	binding-associated region:59-303|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q62696	uniprotkb:B7UR60	intact:EBI-389325	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429878|imex:IM-28455-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:PHx3oQUpUgx6yhlV+meIPESMr88	false	binding-associated region:459-607|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q62936	uniprotkb:B7UR60	intact:EBI-349596|uniprotkb:P70547|ensembl:ENSRNOP00000003741	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:dlg3_rat(display_long)|uniprotkb:Dlg3(gene name)|psi-mi:Dlg3(display_short)|uniprotkb:Dlgh3(gene name synonym)|uniprotkb:Synapse-associated protein 102(gene name synonym)|uniprotkb:PSD-95/SAP90-related protein 1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429889|imex:IM-28455-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:68423|refseq:NP_113827.1|ensembl:ENSRNOG00000002767(gene)|ensembl:ENSRNOT00000003741(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035763|interpro:IPR036028|interpro:IPR036034|mint:Q62936|rcsb pdb:3JXT|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-6794361|reactome:R-RNO-8849932|refseq:XP_006257144.1	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:SE5z/dJFoJsSa0HYyz7KOlFDHio10116	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:U7yxDCgQSQG5zyYqFsKwpK23NsA	false	binding-associated region:398-552|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61234	uniprotkb:B7UR60	intact:EBI-295952|uniprotkb:Q8VEF3|ensembl:ENSMUSP00000028991	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:snta1_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)|uniprotkb:Snt1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429951|imex:IM-28455-58	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0051117"(ATPase binding)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|mint:Q61234|rcsb pdb:1QAV|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|rcsb pdb:1Z86|rcsb pdb:1Z87|rcsb pdb:2ADZ|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|rcsb pdb:2PDZ|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|rcsb pdb:4HOP|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000028991(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|dip:DIP-32898N	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:ENtty34uPh1ZGRmhT4TTIM/OVpI10090	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:q7dmMkAZeNgFaPWqRT8OfFaocck	false	binding-associated region:76-228|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99L88	uniprotkb:B7UR60	intact:EBI-295943|uniprotkb:O35925|ensembl:ENSMUSP00000041294	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:sntb1_mouse(display_long)|uniprotkb:Sntb1(gene name)|psi-mi:Sntb1(display_short)|uniprotkb:Snt2b1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 1(gene name synonym)|uniprotkb:Syntrophin-2(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429962|imex:IM-28455-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|mint:Q99L88|ensembl:ENSMUSG00000060429(gene)|ensembl:ENSMUST00000039769(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_057876.1|refseq:XP_006520734.1	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:s9YcOAVq5wEohYlPv5lLHlu62Sc10090	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:e7mY02gmrz78JJ9SFgKlAVh/qVM	false	binding-associated region:106-252|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13425	uniprotkb:B7UR60	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26429985|imex:IM-28455-60	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	-	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:5tP+GQIYpBLxyqkERQl+OWKrV2A	false	binding-associated region:111-265|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q925E0	uniprotkb:B7UR60	intact:EBI-8521556|uniprotkb:B2RSQ0|intact:UNK-5532739|ensembl:ENSMUSP00000021004	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:sntg2_mouse(display_long)|uniprotkb:Sntg2(gene name)|psi-mi:Sntg2(display_short)|uniprotkb:Syntrophin-5(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26430025|imex:IM-28455-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_766539.2|ensembl:ENSMUSG00000020672(gene)|ensembl:ENSMUST00000021004(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0097109"(neuroligin family protein binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|mint:Q925E0	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	comment:mint|function:Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:8A7Dm4xWGrV9Zeb8BTMq2gTwvcg10090	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:0QGgZ/BLo1++I/yPlWeexphpToI	false	binding-associated region:68-215|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9JIL4	uniprotkb:B7UR60	intact:EBI-7420331|uniprotkb:Q8CDP5|uniprotkb:Q9CQ72|uniprotkb:Q8R4G2|intact:MINT-148595	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:nhrf3_mouse(display_long)|uniprotkb:Pdzk1(gene name)|psi-mi:Pdzk1(display_short)|uniprotkb:Cap70(gene name synonym)|uniprotkb:Nherf3(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger regulatory factor 3"(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26430038|imex:IM-28455-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q9JIL4|refseq:XP_011238480.1|refseq:NP_001139473.1|refseq:NP_067492.2|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:XP_017175164.1|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0015879"(carnitine transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1904064"(positive regulation of cation transmembrane transport)|go:"GO:1905477"(positive regulation of protein localization to membrane)|rcsb pdb:2D90|rcsb pdb:2EDZ|rcsb pdb:3NGH|rcsb pdb:3R68|rcsb pdb:3R69|rcsb pdb:4F8K|rcsb pdb:4R2Z|interpro:IPR036034|refseq:XP_006501896.1	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	comment:mint|function:"A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism (By similarity). May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function"	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:BJgdvpSO4jt9gOQ4q7csJ928GKI10090	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:G6cRubVqEyxXV0ZnRLZXQ5PmpF0	false	binding-associated region:1-128|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99MJ6	uniprotkb:B7UR60	intact:EBI-7455069|uniprotkb:Q8BWE5|intact:MINT-152467	intact:EBI-25435618|ensemblbacteria:CAS08990	psi-mi:nhrf4_mouse(display_long)|uniprotkb:Pdzd3(gene name)|psi-mi:Pdzd3(display_short)|uniprotkb:Pdzk2(gene name synonym)|uniprotkb:Nherf4(gene name synonym)|uniprotkb:PDZ domain-containing protein 3(gene name synonym)|uniprotkb:PDZ domain-containing protein 2(gene name synonym)|uniprotkb:Natrium-phosphate cotransporter IIa C-terminal-associated protein 2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 4(gene name synonym)	psi-mi:b7ur60_eco27(display_long)|uniprotkb:E2348C_1442(locus name)	psi-mi:"MI:0089"(protein array)	Lee et al. (2008)	pubmed:17979986|imex:IM-28455	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:574521(eco27)|taxid:574521("Escherichia coli O127:H6 (strain E2348/69 / EPEC)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26430051|imex:IM-28455-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR031200|interpro:IPR036034|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:NP_573489.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005903"(brush border)|go:"GO:0006811"(ion transport)|go:"GO:0007168"(receptor guanylyl cyclase signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030251"(guanylate cyclase inhibitor activity)|go:"GO:0043296"(apical junction complex)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)	ensemblbacteria:CAS08990(transcript)|ensemblbacteria:E2348C_1442(gene)|refseq:WP_001025663.1	-	comment:mint|function:Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation	-	figure legend:fig. 1b,1c table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/10/13	2020/10/28	rogid:Nlz4RzwY4ilDwdPQALP7wG4HjEk10090	rogid:9JzwwZQrNraeZGU9Yv2lBn78En8574521	rigid:mRHMCziKvpLPrjhr4C/f0cXmugA	false	binding-associated region:1-128|his tag:?-?	binding-associated region:391-440|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)