#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9H329	uniprotkb:P82279	intact:EBI-3941680|uniprotkb:Q9H328|uniprotkb:Q5T4G6|uniprotkb:Q5T4G5|uniprotkb:Q9P2V3|ensembl:ENSP00000363694	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	psi-mi:e41lb_human(display_long)|uniprotkb:EPB41L4B(gene name)|psi-mi:EPB41L4B(display_short)|uniprotkb:EHM2(gene name synonym)|uniprotkb:FERM-containing protein CG1(gene name synonym)|uniprotkb:Protein EHM2(gene name synonym)|uniprotkb:LULU2(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 4B(gene name synonym)	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:"MI:0018"(two hybrid)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26451720|imex:IM-28524-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000095203(gene)|ensembl:ENST00000374566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042060"(wound healing)|go:"GO:0045177"(apical part of cell)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0051549"(positive regulation of keratinocyte migration)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030698|interpro:IPR035963|go:"GO:0031032"(actomyosin structure organization)|refseq:NP_060894.2|refseq:NP_061987.3	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	-	-	-	figure legend:Fig.5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/11/19	2020/11/19	rogid:NSuoD84Y202IDxiauNoP97D55A09606	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rigid:G9q8+RQ1TKtPILLQ0zGqDwelShc	false	sufficient binding region:67-263	sufficient binding region:1370-1406	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P26038	uniprotkb:P82279	intact:EBI-528768|ensembl:ENSP00000353408	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	psi-mi:moes_human(display_long)|uniprotkb:Membrane-organizing extension spike protein(gene name synonym)|uniprotkb:MSN(gene name)|psi-mi:MSN(display_short)	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:"MI:0018"(two hybrid)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26451732|imex:IM-28524-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002435.1|ensembl:ENSG00000147065(gene)|ensembl:ENST00000360270(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001931"(uropod)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005925"(focal adhesion)|go:"GO:0031982"(vesicle)|go:"GO:0042098"(T cell proliferation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070489"(T cell aggregation)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009986"(cell surface)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0072678"(T cell migration)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000401"(regulation of lymphocyte migration)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P26038|rcsb pdb:1E5W|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016323"(basolateral plasma membrane)|rcsb pdb:1EF1|rcsb pdb:1SGH|rcsb pdb:6TXQ|go:"GO:0016324"(apical plasma membrane)|rcsb pdb:6TXS|reactome:R-HSA-437239|reactome:R-HSA-8950505|reactome:R-HSA-9662360|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-9662361|go:"GO:0019901"(protein kinase binding)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030175"(filopodium)|go:"GO:0031143"(pseudopodium)|go:"GO:0031528"(microvillus membrane)|dip:DIP-33841N	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	-	-	-	figure legend:Fig.5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/11/19	2020/11/19	rogid:XYzuC8VtaVyNYyZ2G5wVbxyPPww9606	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rigid:ijNH+mSPv+FnrZxTZ5P5QdoDPJg	false	sufficient binding region:1-306	sufficient binding region:1370-1406	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCM4	uniprotkb:P82279	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:"MI:0018"(two hybrid)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26451740|imex:IM-28524-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	-	-	-	figure legend:Fig.5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/11/19	2020/11/19	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rigid:t0rirXXSjl1ALSI7ZOm2vgSMZo4	false	sufficient binding region:29-353|necessary binding region:29-119	sufficient binding region:1370-1406	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N3R9	uniprotkb:P82279	intact:EBI-2513978|ensembl:ENSP00000261681|ensembl:ENSP00000503321|ensembl:ENSP00000503322|ensembl:ENSP00000503517|ensembl:ENSP00000503713|uniprotkb:Q86T98|uniprotkb:Q8N7I5|uniprotkb:Q7Z631|uniprotkb:Q9H9Q0|uniprotkb:A1L380	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	psi-mi:pals1_human(display_long)|uniprotkb:PALS1(gene name)|psi-mi:PALS1(display_short)|uniprotkb:MAGUK p55 subfamily member 5(gene name synonym)|uniprotkb:MPP5(gene name synonym)|uniprotkb:Membrane protein, palmitoylated 5(gene name synonym)|uniprotkb:Protein associated with Lin-7 1(gene name synonym)	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:"MI:0018"(two hybrid)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26451759|imex:IM-28524-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010467"(gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032288"(myelin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035750"(protein localization to myelin sheath abaxonal region)|go:"GO:0043204"(perikaryon)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR015145(L27-N)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035601|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q8N3R9|rcsb pdb:1Y76|rcsb pdb:3UIT|rcsb pdb:4UU5|rcsb pdb:4UU6|rcsb pdb:4WSI|rcsb pdb:7M4R|rcsb pdb:7NTJ|rcsb pdb:7NTK|reactome:R-HSA-420029|ensembl:ENSG00000072415(gene)|ensembl:ENST00000261681(transcript)|ensembl:ENST00000676464(transcript)|ensembl:ENST00000677382(transcript)|ensembl:ENST00000677835(transcript)|ensembl:ENST00000678380(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|refseq:XP_011535388.1|refseq:XP_011535389.1|refseq:NP_071919.2|refseq:NP_001243479.1|refseq:XP_005268060.1	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	-	-	-	figure legend:Fig.5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/11/19	2020/11/19	rogid:VpQVKlVcuBSs8mztUd9iHqkIXDM9606	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rigid:C95LT0UY9cOB0m3A/xzemwETVkM	false	sufficient binding region:256..256-336..336(IPR001478)	sufficient binding region:1370-1406	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCM4	uniprotkb:Q8N3R9	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	intact:EBI-2513978|ensembl:ENSP00000261681|ensembl:ENSP00000503321|ensembl:ENSP00000503322|ensembl:ENSP00000503517|ensembl:ENSP00000503713|uniprotkb:Q86T98|uniprotkb:Q8N7I5|uniprotkb:Q7Z631|uniprotkb:Q9H9Q0|uniprotkb:A1L380	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:pals1_human(display_long)|uniprotkb:PALS1(gene name)|psi-mi:PALS1(display_short)|uniprotkb:MAGUK p55 subfamily member 5(gene name synonym)|uniprotkb:MPP5(gene name synonym)|uniprotkb:Membrane protein, palmitoylated 5(gene name synonym)|uniprotkb:Protein associated with Lin-7 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26452196|imex:IM-28524-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010467"(gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032288"(myelin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035750"(protein localization to myelin sheath abaxonal region)|go:"GO:0043204"(perikaryon)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR015145(L27-N)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035601|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q8N3R9|rcsb pdb:1Y76|rcsb pdb:3UIT|rcsb pdb:4UU5|rcsb pdb:4UU6|rcsb pdb:4WSI|rcsb pdb:7M4R|rcsb pdb:7NTJ|rcsb pdb:7NTK|reactome:R-HSA-420029|ensembl:ENSG00000072415(gene)|ensembl:ENST00000261681(transcript)|ensembl:ENST00000676464(transcript)|ensembl:ENST00000677382(transcript)|ensembl:ENST00000677835(transcript)|ensembl:ENST00000678380(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|refseq:XP_011535388.1|refseq:XP_011535389.1|refseq:NP_071919.2|refseq:NP_001243479.1|refseq:XP_005268060.1	-	-	-	figure legend:Fig.6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/11/19	2020/11/20	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rogid:VpQVKlVcuBSs8mztUd9iHqkIXDM9606	rigid:YpDoWZKdZn2doIvhTUslvArnXvA	false	sufficient binding region:29-353	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCM4	uniprotkb:Q8N3R9	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	intact:EBI-2513978|ensembl:ENSP00000261681|ensembl:ENSP00000503321|ensembl:ENSP00000503322|ensembl:ENSP00000503517|ensembl:ENSP00000503713|uniprotkb:Q86T98|uniprotkb:Q8N7I5|uniprotkb:Q7Z631|uniprotkb:Q9H9Q0|uniprotkb:A1L380	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:pals1_human(display_long)|uniprotkb:PALS1(gene name)|psi-mi:PALS1(display_short)|uniprotkb:MAGUK p55 subfamily member 5(gene name synonym)|uniprotkb:MPP5(gene name synonym)|uniprotkb:Membrane protein, palmitoylated 5(gene name synonym)|uniprotkb:Protein associated with Lin-7 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26452206|imex:IM-28524-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010467"(gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032288"(myelin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035750"(protein localization to myelin sheath abaxonal region)|go:"GO:0043204"(perikaryon)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR015145(L27-N)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035601|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q8N3R9|rcsb pdb:1Y76|rcsb pdb:3UIT|rcsb pdb:4UU5|rcsb pdb:4UU6|rcsb pdb:4WSI|rcsb pdb:7M4R|rcsb pdb:7NTJ|rcsb pdb:7NTK|reactome:R-HSA-420029|ensembl:ENSG00000072415(gene)|ensembl:ENST00000261681(transcript)|ensembl:ENST00000676464(transcript)|ensembl:ENST00000677382(transcript)|ensembl:ENST00000677835(transcript)|ensembl:ENST00000678380(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|refseq:XP_011535388.1|refseq:XP_011535389.1|refseq:NP_071919.2|refseq:NP_001243479.1|refseq:XP_005268060.1	-	-	-	figure legend:Fig.6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/11/19	2020/11/20	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rogid:VpQVKlVcuBSs8mztUd9iHqkIXDM9606	rigid:YpDoWZKdZn2doIvhTUslvArnXvA	false	sufficient binding region:29-353	sufficient binding region:408-466	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCM4	uniprotkb:P82279	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:"MI:0090"(protein complementation assay)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26451787|imex:IM-28524-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	-	-	-	figure legend:Fig.5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/11/19	2020/11/19	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rigid:t0rirXXSjl1ALSI7ZOm2vgSMZo4	false	sufficient binding region:29-353|necessary binding region:29-119|tag:?-?	sufficient binding region:1370-1406|tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N3R9	uniprotkb:P82279	intact:EBI-2513978|ensembl:ENSP00000261681|ensembl:ENSP00000503321|ensembl:ENSP00000503322|ensembl:ENSP00000503517|ensembl:ENSP00000503713|uniprotkb:Q86T98|uniprotkb:Q8N7I5|uniprotkb:Q7Z631|uniprotkb:Q9H9Q0|uniprotkb:A1L380	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	psi-mi:pals1_human(display_long)|uniprotkb:PALS1(gene name)|psi-mi:PALS1(display_short)|uniprotkb:MAGUK p55 subfamily member 5(gene name synonym)|uniprotkb:MPP5(gene name synonym)|uniprotkb:Membrane protein, palmitoylated 5(gene name synonym)|uniprotkb:Protein associated with Lin-7 1(gene name synonym)	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:"MI:0090"(protein complementation assay)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26451805|imex:IM-28524-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010467"(gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032288"(myelin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035750"(protein localization to myelin sheath abaxonal region)|go:"GO:0043204"(perikaryon)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR015145(L27-N)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035601|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q8N3R9|rcsb pdb:1Y76|rcsb pdb:3UIT|rcsb pdb:4UU5|rcsb pdb:4UU6|rcsb pdb:4WSI|rcsb pdb:7M4R|rcsb pdb:7NTJ|rcsb pdb:7NTK|reactome:R-HSA-420029|ensembl:ENSG00000072415(gene)|ensembl:ENST00000261681(transcript)|ensembl:ENST00000676464(transcript)|ensembl:ENST00000677382(transcript)|ensembl:ENST00000677835(transcript)|ensembl:ENST00000678380(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|refseq:XP_011535388.1|refseq:XP_011535389.1|refseq:NP_071919.2|refseq:NP_001243479.1|refseq:XP_005268060.1	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	-	-	-	figure legend:Fig.5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/11/19	2020/11/19	rogid:VpQVKlVcuBSs8mztUd9iHqkIXDM9606	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rigid:C95LT0UY9cOB0m3A/xzemwETVkM	false	tag:?-?|sufficient binding region:256..256-336..336	tag:?-?|sufficient binding region:1370-1406	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9HCM4	uniprotkb:P82279	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:"MI:0096"(pull down)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26451871|imex:IM-28524-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	-	-	-	figure legend:Fig.5C Supp. Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/19	2020/11/26	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rigid:t0rirXXSjl1ALSI7ZOm2vgSMZo4	false	sufficient binding region:29-353|his tag:?-?|maltose binding protein tag:?-?|necessary binding region:29-119	sufficient binding region:1370-1406|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5IJ48	uniprotkb:Q9HCM4	intact:EBI-26302775|ensembl:ENSP00000362734|uniprotkb:A2A3N4|uniprotkb:Q0QD46|uniprotkb:Q5JS41|uniprotkb:Q5JS43|uniprotkb:Q6ZTA9|uniprotkb:Q6ZWI6	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	psi-mi:crum2_human(display_long)|uniprotkb:CRB2(gene name)|psi-mi:CRB2(display_short)|uniprotkb:Crumbs-like protein 2(gene name synonym)	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26451885|imex:IM-28524-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007601"(visual perception)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014028"(notochord formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|ensembl:ENSG00000148204(gene)|ensembl:ENST00000373631(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001756"(somitogenesis)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0050896"(response to stimulus)|go:"GO:0055111"(ingression involved in gastrulation with mouth forming second)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072359"(circulatory system development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:2WO6|refseq:NP_775960.4|refseq:XP_005251991.1	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	-	-	-	figure legend:Fig.5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/19	2020/11/26	rogid:OAqOD+Pj//NMpUYn2R5eqguGEkw9606	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rigid:dadWb2sotNynjOfFc6xihC5yea4	false	sufficient binding region:1249-1285|his tag:?-?|maltose binding protein tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9HCM4	uniprotkb:Q8N3R9	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	intact:EBI-2513978|ensembl:ENSP00000261681|ensembl:ENSP00000503321|ensembl:ENSP00000503322|ensembl:ENSP00000503517|ensembl:ENSP00000503713|uniprotkb:Q86T98|uniprotkb:Q8N7I5|uniprotkb:Q7Z631|uniprotkb:Q9H9Q0|uniprotkb:A1L380	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:pals1_human(display_long)|uniprotkb:PALS1(gene name)|psi-mi:PALS1(display_short)|uniprotkb:MAGUK p55 subfamily member 5(gene name synonym)|uniprotkb:MPP5(gene name synonym)|uniprotkb:Membrane protein, palmitoylated 5(gene name synonym)|uniprotkb:Protein associated with Lin-7 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26452214|imex:IM-28524-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010467"(gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032288"(myelin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035750"(protein localization to myelin sheath abaxonal region)|go:"GO:0043204"(perikaryon)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR015145(L27-N)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035601|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q8N3R9|rcsb pdb:1Y76|rcsb pdb:3UIT|rcsb pdb:4UU5|rcsb pdb:4UU6|rcsb pdb:4WSI|rcsb pdb:7M4R|rcsb pdb:7NTJ|rcsb pdb:7NTK|reactome:R-HSA-420029|ensembl:ENSG00000072415(gene)|ensembl:ENST00000261681(transcript)|ensembl:ENST00000676464(transcript)|ensembl:ENST00000677382(transcript)|ensembl:ENST00000677835(transcript)|ensembl:ENST00000678380(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|refseq:XP_011535388.1|refseq:XP_011535389.1|refseq:NP_071919.2|refseq:NP_001243479.1|refseq:XP_005268060.1	-	-	-	figure legend:Fig.6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/19	2020/11/27	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rogid:VpQVKlVcuBSs8mztUd9iHqkIXDM9606	rigid:YpDoWZKdZn2doIvhTUslvArnXvA	false	sufficient binding region:29-353|his tag:?-?|maltose binding protein tag:?-?	sufficient binding region:408-466|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BUF7	uniprotkb:Q9HCM4	intact:EBI-9844372|uniprotkb:A8KA91|uniprotkb:D6W643|uniprotkb:Q8N0V8|uniprotkb:Q8WVA0|ensembl:ENSP00000310123|ensembl:ENSP00000469707|ensembl:ENSP00000472010	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	psi-mi:crum3_human(display_long)|uniprotkb:CRB3(gene name)|psi-mi:CRB3(display_short)|uniprotkb:UNQ588/PRO1158(orf name)	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26474377|imex:IM-28524-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_777378.1|refseq:NP_631900.1|refseq:NP_777377.1|ensembl:ENSG00000130545(gene)|ensembl:ENST00000308243(transcript)|ensembl:ENST00000598494(transcript)|ensembl:ENST00000600229(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901890"(positive regulation of cell junction assembly)|rcsb pdb:5I7Z|reactome:R-HSA-420029|go:"GO:0030054"(cell junction)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	-	-	-	figure legend:Fig.5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/19	2020/11/26	rogid:PJ8C9nnERz7UQ+pMLRZjV0Fh/M89606	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rigid:ZM+1Gz1b5jJZBBsXvajaj2WUXiQ	false	sufficient binding region:84-120|his tag:?-?|maltose binding protein tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P82279	uniprotkb:A0A3Q1LY00	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	intact:EBI-26451960|ensembl:ENSBTAP00000062138	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:a0a3q1ly00_bovin(display_long)|uniprotkb:PALS1(gene name)|psi-mi:PALS1(display_short)|uniprotkb:MPP5(gene name synonym)|uniprotkb:Protein PALS1(gene name synonym)|uniprotkb:Protein associated with Lin-7 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26451920|imex:IM-28524-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	go:"GO:0012505"(endomembrane system)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035750"(protein localization to myelin sheath abaxonal region)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0045177"(apical part of cell)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|ensembl:ENSBTAG00000011767(gene)|ensembl:ENSBTAT00000081434(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010467"(gene expression)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR015145(L27-N)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035601|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|refseq:NP_001192880.1|refseq:XP_015328720.1|refseq:XP_015328721.1	-	-	-	figure legend:Fig.5E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/19	2020/11/19	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rogid:sROfcRNMIDIs7SQYeQ8+ZL4kTxY9913	rigid:yURj5Fn3CU6+qfPHOwB2xpDPZV0	false	sufficient binding region:1370-1406|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P82279	uniprotkb:Q58CU2	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	intact:EBI-26451934|ensembl:ENSBTAP00000024277	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:e41l5_bovin(display_long)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26451920|imex:IM-28524-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	ensembl:ENSBTAG00000018236(gene)|ensembl:ENSBTAT00000024277(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0031032"(actomyosin structure organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|refseq:NP_001030461.1	-	-	-	figure legend:Fig.5E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/19	2020/11/19	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rogid:Eh0989FUnJELTbjf3jBbIV3JGBI9913	rigid:yURj5Fn3CU6+qfPHOwB2xpDPZV0	false	sufficient binding region:1370-1406|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q58CU2	uniprotkb:P82279	intact:EBI-26451934|ensembl:ENSBTAP00000024277	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	psi-mi:e41l5_bovin(display_long)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:"MI:0096"(pull down)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26474448|imex:IM-28524-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAG00000018236(gene)|ensembl:ENSBTAT00000024277(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0031032"(actomyosin structure organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|refseq:NP_001030461.1	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	-	-	-	figure legend:Fig.5E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/19	2020/11/27	rogid:Eh0989FUnJELTbjf3jBbIV3JGBI9913	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rigid:b6ssAWJg+cMOqSECI5q4VKzwSCo	false	-	sufficient binding region:1370-1402|glutathione s tranferase tag:n-n|necessary binding region:1377-1379	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A0A3Q1LY00	uniprotkb:P82279	intact:EBI-26451960|ensembl:ENSBTAP00000062138	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	psi-mi:a0a3q1ly00_bovin(display_long)|uniprotkb:PALS1(gene name)|psi-mi:PALS1(display_short)|uniprotkb:MPP5(gene name synonym)|uniprotkb:Protein PALS1(gene name synonym)|uniprotkb:Protein associated with Lin-7 1(gene name synonym)	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:"MI:0096"(pull down)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26474457|imex:IM-28524-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0012505"(endomembrane system)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035750"(protein localization to myelin sheath abaxonal region)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0045177"(apical part of cell)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|ensembl:ENSBTAG00000011767(gene)|ensembl:ENSBTAT00000081434(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010467"(gene expression)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR015145(L27-N)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035601|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|refseq:NP_001192880.1|refseq:XP_015328720.1|refseq:XP_015328721.1	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	-	-	-	figure legend:Fig.5E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/19	2020/11/27	rogid:sROfcRNMIDIs7SQYeQ8+ZL4kTxY9913	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rigid:WDCkI/ZfhvFiQUGD2JGvlm+EK/4	false	-	glutathione s tranferase tag:n-n|sufficient binding region:1370-1406|necessary binding region:1403-1406	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9HCM4	uniprotkb:Q8N3R9	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	intact:EBI-2513978|ensembl:ENSP00000261681|ensembl:ENSP00000503321|ensembl:ENSP00000503322|ensembl:ENSP00000503517|ensembl:ENSP00000503713|uniprotkb:Q86T98|uniprotkb:Q8N7I5|uniprotkb:Q7Z631|uniprotkb:Q9H9Q0|uniprotkb:A1L380	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:pals1_human(display_long)|uniprotkb:PALS1(gene name)|psi-mi:PALS1(display_short)|uniprotkb:MAGUK p55 subfamily member 5(gene name synonym)|uniprotkb:MPP5(gene name synonym)|uniprotkb:Membrane protein, palmitoylated 5(gene name synonym)|uniprotkb:Protein associated with Lin-7 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26452315|imex:IM-28524-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010467"(gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032288"(myelin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035750"(protein localization to myelin sheath abaxonal region)|go:"GO:0043204"(perikaryon)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR015145(L27-N)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035601|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q8N3R9|rcsb pdb:1Y76|rcsb pdb:3UIT|rcsb pdb:4UU5|rcsb pdb:4UU6|rcsb pdb:4WSI|rcsb pdb:7M4R|rcsb pdb:7NTJ|rcsb pdb:7NTK|reactome:R-HSA-420029|ensembl:ENSG00000072415(gene)|ensembl:ENST00000261681(transcript)|ensembl:ENST00000676464(transcript)|ensembl:ENST00000677382(transcript)|ensembl:ENST00000677835(transcript)|ensembl:ENST00000678380(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|refseq:XP_011535388.1|refseq:XP_011535389.1|refseq:NP_071919.2|refseq:NP_001243479.1|refseq:XP_005268060.1	-	-	-	figure legend:Fig.6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/11/19	2020/11/20	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rogid:VpQVKlVcuBSs8mztUd9iHqkIXDM9606	rigid:YpDoWZKdZn2doIvhTUslvArnXvA	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9HCM4	uniprotkb:P82279	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	intact:EBI-1048648|uniprotkb:Q5K3A6|uniprotkb:Q5TC28|uniprotkb:Q5VUT1|uniprotkb:Q6N027|uniprotkb:Q8WWY0|uniprotkb:A2A308|uniprotkb:B9EG71|intact:EBI-1058755|uniprotkb:Q8WWY1|uniprotkb:B7Z5T2|ensembl:ENSP00000356370	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:crum1_human(display_long)|uniprotkb:CRB1(gene name)|psi-mi:CRB1(display_short)	psi-mi:"MI:0096"(pull down)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26452541|imex:IM-28524-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	refseq:NP_001180569.1|refseq:NP_957705.1|refseq:NP_001244894.1|refseq:NP_001244895.1|ensembl:ENSG00000134376(gene)|ensembl:ENST00000367400(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010467"(gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060060"(post-embryonic retina morphogenesis in camera-type eye)|go:"GO:0061159"(establishment of bipolar cell polarity involved in cell morphogenesis)|go:"GO:0071482"(cellular response to light stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|rcsb pdb:4UU5	-	-	-	figure legend:Supp. Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/11/19	2020/11/20	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rogid:ootDiV2LmQtjcB1YBjcBhFimWq09606	rigid:t0rirXXSjl1ALSI7ZOm2vgSMZo4	false	35s radiolabel:?-?	sufficient binding region:1370-1402|glutathione s tranferase tag:n-n|necessary binding region:1377-1379	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q9HCM4	uniprotkb:Q9BUF7	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	intact:EBI-9844372|uniprotkb:A8KA91|uniprotkb:D6W643|uniprotkb:Q8N0V8|uniprotkb:Q8WVA0|ensembl:ENSP00000310123|ensembl:ENSP00000469707|ensembl:ENSP00000472010	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:crum3_human(display_long)|uniprotkb:CRB3(gene name)|psi-mi:CRB3(display_short)|uniprotkb:UNQ588/PRO1158(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26453340|imex:IM-28524-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	refseq:NP_777378.1|refseq:NP_631900.1|refseq:NP_777377.1|ensembl:ENSG00000130545(gene)|ensembl:ENST00000308243(transcript)|ensembl:ENST00000598494(transcript)|ensembl:ENST00000600229(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901890"(positive regulation of cell junction assembly)|rcsb pdb:5I7Z|reactome:R-HSA-420029|go:"GO:0030054"(cell junction)	-	-	-	figure legend:Supp Fg. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2020/11/19	2020/11/23	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rogid:PJ8C9nnERz7UQ+pMLRZjV0Fh/M89606	rigid:ZM+1Gz1b5jJZBBsXvajaj2WUXiQ	false	myc tag:?-?	tag:n-n|sufficient binding region:84-116	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9HCM4	uniprotkb:Q9BUF7	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	intact:EBI-9844372|uniprotkb:A8KA91|uniprotkb:D6W643|uniprotkb:Q8N0V8|uniprotkb:Q8WVA0|ensembl:ENSP00000310123|ensembl:ENSP00000469707|ensembl:ENSP00000472010	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:crum3_human(display_long)|uniprotkb:CRB3(gene name)|psi-mi:CRB3(display_short)|uniprotkb:UNQ588/PRO1158(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Gosens et al. (2007)	imex:IM-28524|pubmed:17920587	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26453357|imex:IM-28524-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	refseq:NP_777378.1|refseq:NP_631900.1|refseq:NP_777377.1|ensembl:ENSG00000130545(gene)|ensembl:ENST00000308243(transcript)|ensembl:ENST00000598494(transcript)|ensembl:ENST00000600229(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901890"(positive regulation of cell junction assembly)|rcsb pdb:5I7Z|reactome:R-HSA-420029|go:"GO:0030054"(cell junction)	-	-	-	figure legend:Supp Fg. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2020/11/19	2020/11/23	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rogid:PJ8C9nnERz7UQ+pMLRZjV0Fh/M89606	rigid:ZM+1Gz1b5jJZBBsXvajaj2WUXiQ	false	myc tag:?-?	tag:n-n|sufficient binding region:84-116	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)