#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P20292 uniprotkb:P20292 intact:EBI-3904621|uniprotkb:Q5VV04|ensembl:ENSP00000369858 intact:EBI-3904621|uniprotkb:Q5VV04|ensembl:ENSP00000369858 psi-mi:al5ap_human(display_long)|uniprotkb:ALOX5AP(gene name)|psi-mi:ALOX5AP(display_short)|uniprotkb:FLAP(gene name synonym)|uniprotkb:MK-886-binding protein(gene name synonym) psi-mi:al5ap_human(display_long)|uniprotkb:ALOX5AP(gene name)|psi-mi:ALOX5AP(display_short)|uniprotkb:FLAP(gene name synonym)|uniprotkb:MK-886-binding protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ferguson et al. (2007) pubmed:17600184|imex:IM-28570 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-26452342|wwpdb:2Q7M|wwpdb:2Q7R|imex:IM-28570-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191335.1|refseq:NP_001620.2|ensembl:ENSG00000132965(gene)|ensembl:ENST00000380490(transcript)|go:"GO:0002540"(leukotriene production involved in inflammatory response)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0004051"(arachidonate 5-lipoxygenase activity)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004464"(leukotriene-C4 synthase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0005635"(nuclear envelope)|interpro:IPR001446(5-lipoxygenase-activating protein)|interpro:IPR018295|interpro:IPR023352|rcsb pdb:2Q7M|rcsb pdb:2Q7R|rcsb pdb:6VGC|rcsb pdb:6VGI|reactome:R-HSA-2142688|reactome:R-HSA-2142691|reactome:R-HSA-2142700|interpro:IPR001129("Membrane-associated, eicosanoid and glutathione metabolism (MAPEG)") refseq:NP_001191335.1|refseq:NP_001620.2|ensembl:ENSG00000132965(gene)|ensembl:ENST00000380490(transcript)|go:"GO:0002540"(leukotriene production involved in inflammatory response)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0004051"(arachidonate 5-lipoxygenase activity)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004464"(leukotriene-C4 synthase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0005635"(nuclear envelope)|interpro:IPR001446(5-lipoxygenase-activating protein)|interpro:IPR018295|interpro:IPR023352|rcsb pdb:2Q7M|rcsb pdb:2Q7R|rcsb pdb:6VGC|rcsb pdb:6VGI|reactome:R-HSA-2142688|reactome:R-HSA-2142691|reactome:R-HSA-2142700|interpro:IPR001129("Membrane-associated, eicosanoid and glutathione metabolism (MAPEG)") - - - figure legend:Fig 1, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/11/20 2020/11/20 rogid:voBvHh41O8qvD1eBm0eaLiWPIdI9606 rogid:voBvHh41O8qvD1eBm0eaLiWPIdI9606 rigid:xo2qs3lms5ZHiriqeRT0fuTuyLU false his tag:c-c his tag:c-c 3 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)