#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P59594 uniprotkb:P35247 intact:EBI-15582614|intact:EBI-16063777|uniprotkb:Q6QU82|uniprotkb:Q7T696|uniprotkb:Q7TA19|uniprotkb:Q7TFA2|uniprotkb:Q7TFB1|uniprotkb:Q80BV6 intact:EBI-11316157|uniprotkb:Q5T0M3|uniprotkb:Q6FH08|uniprotkb:Q86YK9|uniprotkb:Q8TCD8|uniprotkb:Q9UCJ2|uniprotkb:Q9UCJ3|ensembl:ENSP00000361366 psi-mi:spike_sars(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:sftpd_human(display_long)|uniprotkb:SFTPD(gene name)|psi-mi:SFTPD(display_short)|uniprotkb:COLEC7(gene name synonym)|uniprotkb:PSPD(gene name synonym)|uniprotkb:SFTP4(gene name synonym)|uniprotkb:Collectin-7(gene name synonym)|uniprotkb:Lung surfactant protein D(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Leth-Larsen et al. (2006) pubmed:17412287|imex:IM-27905 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25510559|imex:IM-27905-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR032500|interpro:IPR036326|interpro:IPR042578|interpro:IPR043002|interpro:IPR043473|interpro:IPR043607|interpro:IPR044341|interpro:IPR044370|interpro:IPR044873|interpro:IPR044874|rcsb pdb:1Q4Z|rcsb pdb:1T7G|rcsb pdb:1U4K|rcsb pdb:1WNC|rcsb pdb:1WYY|rcsb pdb:1XJP|rcsb pdb:1ZV7|rcsb pdb:1ZV8|rcsb pdb:1ZVB|rcsb pdb:2AJF|rcsb pdb:2BEQ|rcsb pdb:2BEZ|rcsb pdb:2DD8|rcsb pdb:2FXP|rcsb pdb:2GHV|rcsb pdb:2GHW|rcsb pdb:2RUM|rcsb pdb:2RUN|rcsb pdb:2RUO|rcsb pdb:3BGF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:5WRG|rcsb pdb:5X4S|rcsb pdb:5X58|rcsb pdb:5X5B|rcsb pdb:5XJK|rcsb pdb:5XLR|rcsb pdb:5ZVM|rcsb pdb:6ACC|rcsb pdb:6ACD|rcsb pdb:6ACG|rcsb pdb:6ACK|rcsb pdb:6CRV|rcsb pdb:6CRW|rcsb pdb:6CRX|rcsb pdb:6CRZ|rcsb pdb:6CS0|rcsb pdb:6CS1|rcsb pdb:6CS2|rcsb pdb:6M3W|rcsb pdb:6NB6|rcsb pdb:6NB7|rcsb pdb:6VW1|rcsb pdb:6WAQ|rcsb pdb:7JN5|rcsb pdb:6ACJ|dip:DIP-29105N|reactome:R-HSA-9679509|reactome:R-HSA-9683686|reactome:R-HSA-9683701|refseq:NP_828851.1|reactome:R-HSA-9678110 refseq:NP_003010.4|refseq:XP_011538389.1|rcsb pdb:2GGU|rcsb pdb:2GGX|rcsb pdb:2ORJ|rcsb pdb:2ORK|rcsb pdb:2OS9|rcsb pdb:2RIA|rcsb pdb:2RIB|rcsb pdb:2RIC|rcsb pdb:2RID|rcsb pdb:2RIE|rcsb pdb:3DBZ|rcsb pdb:3G81|rcsb pdb:3G83|rcsb pdb:3G84|rcsb pdb:3IKN|rcsb pdb:3IKP|rcsb pdb:3IKQ|rcsb pdb:3IKR|rcsb pdb:4E52|rcsb pdb:4M17|rcsb pdb:4M18|rcsb pdb:5OXR|rcsb pdb:5OXS|reactome:R-HSA-166016|reactome:R-HSA-168179|reactome:R-HSA-198933|reactome:R-HSA-391160|reactome:R-HSA-5683826|reactome:R-HSA-5686938|reactome:R-HSA-5688849|reactome:R-HSA-5688890|ensembl:ENSG00000133661(gene)|ensembl:ENST00000372292(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0045087"(innate immune response)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048286"(lung alveolus development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0052405"|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1905226"(regulation of adhesion of symbiont to host epithelial cell)|interpro:IPR001304(C-type lectin)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR015097(Lung surfactant protein D coiled-coil trimerisation)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033990|rcsb pdb:1B08|rcsb pdb:1M7L|rcsb pdb:1PW9|rcsb pdb:1PWB - - - figure legend:Fig. 4 A-C|antagonist:"CHEBI:37684 - mannose"|antagonist:"CHEBI:64755 - EDTA(2−)"|antagonist:"CHEBI:17306 - maltose"|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/14 2020/04/14 rogid:H4uZUhfNNQNcF4O+7CmC50IoAi8694009 rogid:YVPGpA6rwjdTjpc67Y8V8EoFiWo9606 rigid:vT30Q+cwKdITIA7swPxbw0zTpDQ false - myc tag:c-c|his tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)