#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00533-4 uniprotkb:Q96JA1 intact:EBI-25434613|ensembl:ENSP00000342376 intact:EBI-2865191|uniprotkb:Q9BYB8|uniprotkb:Q96CF9|uniprotkb:Q6IQ51|uniprotkb:Q9UFI4|ensembl:ENSP00000273261 psi-mi:p00533-4(display_long)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:ERBB(gene name synonym)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:HER1(gene name synonym) psi-mi:lrig1_human(display_long)|uniprotkb:LRIG1(gene name)|psi-mi:LRIG1(display_short)|uniprotkb:LIG1(gene name synonym) psi-mi:"MI:0047"(far western blotting) Goldoni et al. (2007) imex:IM-27741|pubmed:16847455 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25434591|imex:IM-27741-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146648(gene)|ensembl:ENST00000342916(transcript)|intact:EBI-297353(isoform-parent) refseq:NP_056356.2|ensembl:ENSG00000144749(gene)|ensembl:ENST00000273261(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022405"(hair cycle process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032474"(otolith morphogenesis)|go:"GO:0060384"(innervation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032675|interpro:IPR036179|rcsb pdb:4U7L|rcsb pdb:4U7M|reactome:R-HSA-177929|reactome:R-HSA-6807004 - - - figure legend:5F|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/11 2020/02/24 rogid:KEt1NOcj77W++zqoZ3ue192UELc9606 rogid:bnp2t5D9UqLg2EqOUJg6P6BVaE09606 rigid:aTMrXLvN9y6q+RMNG1ydAdGhPqo false - his tag:c-c|sufficient binding region:42-493(IPR001611)|tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P00533-4 uniprotkb:Q96JA1 intact:EBI-25434613|ensembl:ENSP00000342376 intact:EBI-2865191|uniprotkb:Q9BYB8|uniprotkb:Q96CF9|uniprotkb:Q6IQ51|uniprotkb:Q9UFI4|ensembl:ENSP00000273261 psi-mi:p00533-4(display_long)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:ERBB(gene name synonym)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:HER1(gene name synonym) psi-mi:lrig1_human(display_long)|uniprotkb:LRIG1(gene name)|psi-mi:LRIG1(display_short)|uniprotkb:LIG1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Goldoni et al. (2007) imex:IM-27741|pubmed:16847455 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25434636|imex:IM-27741-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146648(gene)|ensembl:ENST00000342916(transcript)|intact:EBI-297353(isoform-parent) refseq:NP_056356.2|ensembl:ENSG00000144749(gene)|ensembl:ENST00000273261(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022405"(hair cycle process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032474"(otolith morphogenesis)|go:"GO:0060384"(innervation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032675|interpro:IPR036179|rcsb pdb:4U7L|rcsb pdb:4U7M|reactome:R-HSA-177929|reactome:R-HSA-6807004 go:"GO:0009986"(cell surface) - - figure legend:8i|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/11 2020/02/24 rogid:KEt1NOcj77W++zqoZ3ue192UELc9606 rogid:bnp2t5D9UqLg2EqOUJg6P6BVaE09606 rigid:aTMrXLvN9y6q+RMNG1ydAdGhPqo false - his tag:c-c|sufficient binding region:42-493(IPR001611)|tag:n-n - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry)