#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O43765 uniprotkb:P59635 intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym) psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:"MI:0018"(two hybrid) Fielding et al. (2006) pubmed:16580632|imex:IM-27925 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25566121|imex:IM-27925-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1 interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 - - - figure legend:na|comment:"The positive cDNA clones were sequenced and analyzed using BLAST; four of the positive clones contained complete ORFs that showed nucleotide sequence identity to human (h) SGT."|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/04/17 2020/04/17 rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rigid:FStUCoPfjiDSPbw5B5ux22sztNk false - sufficient binding region:1-95 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O43765 uniprotkb:P59635 intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym) psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fielding et al. (2006) pubmed:16580632|imex:IM-27925 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25566158|imex:IM-27925-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1 interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 - - - figure legend:Fig. 1B, Fig. 4|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/04/17 2020/04/17 rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rigid:FStUCoPfjiDSPbw5B5ux22sztNk false flag tag:n-n|sufficient binding region:1-158|necessary binding region:126-158(IPR019734) ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P59635 uniprotkb:P59596 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fielding et al. (2006) pubmed:16580632|imex:IM-27925 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25566227|imex:IM-27925-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - - - figure legend:Fig. 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/04/17 2020/04/17 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:N+l2HNiNsWXGxDuC7OT/qxnKgeQ false myc tag:c-c ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P59635 uniprotkb:P59637 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fielding et al. (2006) pubmed:16580632|imex:IM-27925 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25566244|imex:IM-27925-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 - - - figure legend:Fig. 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/04/17 2020/04/17 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rigid:AsEVvyXGA7rmtQtCgArW7LQl/Y0 false myc tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5MAG3 uniprotkb:P59635 intact:EBI-25566189 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 psi-mi:q5mag3_chlae(display_long) psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fielding et al. (2006) pubmed:16580632|imex:IM-27925 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25566180|imex:IM-27925-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR032374|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR019734 interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 - - - figure legend:Fig. 1B|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/04/17 2020/04/17 rogid:0Djtt0tJyrof7JDX5ZFJX2C1v/w9534 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rigid:cmBu7RXW3yUE8GeOggBjkkxMJHo false - ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O43765 uniprotkb:P59635 intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym) psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:"MI:0663"(confocal microscopy) Fielding et al. (2006) pubmed:16580632|imex:IM-27925 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25566204|imex:IM-27925-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1 interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 - - - figure legend:Fig. 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/04/17 2020/04/17 rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rigid:FStUCoPfjiDSPbw5B5ux22sztNk false flag tag:n-n ha tag:c-c - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)