#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04692	uniprotkb:P04692	intact:EBI-1374736|uniprotkb:P06469|uniprotkb:P18342|uniprotkb:P18343|uniprotkb:P18344|uniprotkb:P19354|uniprotkb:Q53X09|uniprotkb:Q63582|uniprotkb:Q63608|uniprotkb:Q63609|ensembl:ENSRNOP00000048499	intact:EBI-1374736|uniprotkb:P06469|uniprotkb:P18342|uniprotkb:P18343|uniprotkb:P18344|uniprotkb:P19354|uniprotkb:Q53X09|uniprotkb:Q63582|uniprotkb:Q63608|uniprotkb:Q63609|ensembl:ENSRNOP00000048499	psi-mi:tpm1_rat(display_long)|uniprotkb:Tpm1(gene name)|psi-mi:Tpm1(display_short)|uniprotkb:Alpha-tm(gene name synonym)|uniprotkb:Tpma(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)	psi-mi:tpm1_rat(display_long)|uniprotkb:Tpm1(gene name)|psi-mi:Tpm1(display_short)|uniprotkb:Alpha-tm(gene name synonym)|uniprotkb:Tpma(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Brown et al. (2005)	pubmed:16365313|imex:IM-27935	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25567688|imex:IM-27935-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3898|refseq:NP_001029241.1|refseq:NP_001029244.1|refseq:NP_001029245.1|refseq:NP_001029246.1|refseq:NP_001029247.1|refseq:NP_062004.1|refseq:NP_001288265.1|refseq:NP_001288665.1|dip:DIP-29020N|ensembl:ENSRNOG00000018184(gene)|ensembl:ENSRNOT00000048044(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051693"(actin filament capping)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|rcsb pdb:1IHQ|rcsb pdb:1MV4|rcsb pdb:1TMZ|rcsb pdb:2B9C|rcsb pdb:2G9J|rcsb pdb:3AZD|reactome:R-RNO-390522|reactome:R-RNO-445355	rgd:3898|refseq:NP_001029241.1|refseq:NP_001029244.1|refseq:NP_001029245.1|refseq:NP_001029246.1|refseq:NP_001029247.1|refseq:NP_062004.1|refseq:NP_001288265.1|refseq:NP_001288665.1|dip:DIP-29020N|ensembl:ENSRNOG00000018184(gene)|ensembl:ENSRNOT00000048044(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051693"(actin filament capping)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|rcsb pdb:1IHQ|rcsb pdb:1MV4|rcsb pdb:1TMZ|rcsb pdb:2B9C|rcsb pdb:2G9J|rcsb pdb:3AZD|reactome:R-RNO-390522|reactome:R-RNO-445355	wwpdb:2b9c	comment:"difference in PDB and UniProt sequence: Met at position 88. Is that an N-terminal tag? How to annotate it?"	comment:"difference in PDB and UniProt sequence: Met at position 88. Is that an N-terminal tag? How to annotate it?"	figure legend:1/a|3d-r-factors:Rwork=0.256  Rfree=0.296|3d-resolution:2.3Å|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/04/21	2020/04/30	rogid:d/imATvus0XZvr7i//2MtbXZ7Pw10116	rogid:d/imATvus0XZvr7i//2MtbXZ7Pw10116	rigid:qt6fICSs484Z+CHDgjnDevlTdVs	false	sufficient binding region:89-208("SO:0001080")|fusion protein:c-c	sufficient binding region:89-208("SO:0001080")|fusion protein:c-c	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)