#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q16740-PRO_0000005516	uniprotkb:Q16740-PRO_0000005516	intact:EBI-25815820	intact:EBI-25815820	psi-mi:q16740-pro_0000005516(display_long)|uniprotkb:CLPP(gene name)|psi-mi:CLPP(display_short)|uniprotkb:Endopeptidase Clp(gene name synonym)	psi-mi:q16740-pro_0000005516(display_long)|uniprotkb:CLPP(gene name)|psi-mi:CLPP(display_short)|uniprotkb:Endopeptidase Clp(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Kang et al. (2004)	pubmed:15522782|imex:IM-28396	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25815815|wwpdb:1tg6|imex:IM-28396-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1056029(chain-parent)	intact:EBI-1056029(chain-parent)	-	chain-seq-start:57|chain-seq-end:277	chain-seq-start:57|chain-seq-end:277	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2020/08/18	2020/08/20	rogid:NI9vS/tAKFh0iOSRNzRVlHUxUbc9606	rogid:NI9vS/tAKFh0iOSRNzRVlHUxUbc9606	rigid:LQhBoVIdJhfQl/Vkdn1XLP97TEI	false	-	-	7	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O76031	intact:EBI-25815911	intact:EBI-1052667|uniprotkb:A1L428|uniprotkb:A8K8F1|uniprotkb:Q9H4D9|uniprotkb:B9EGI8|ensembl:ENSP00000300107	-	psi-mi:clpx_human(display_long)|uniprotkb:CLPX(gene name)|psi-mi:CLPX(display_short)	psi-mi:faphmalvpv(display_short)|psi-mi:EBI-25815911(display_long)	psi-mi:"MI:0435"(protease assay)	Kang et al. (2004)	pubmed:15522782|imex:IM-28396	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25815919|imex:IM-28396-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:1343"(enzyme regulator)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	refseq:NP_006651.2|ensembl:ENSG00000166855(gene)|ensembl:ENST00000300107(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009368"(endopeptidase Clp complex)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|go:"GO:0009841"(mitochondrial endopeptidase Clp complex)|mint:O76031|dip:DIP-50293N	-	-	-	-	figure legend:Fig. 6A, Table 2|comment:Removal of the 28 C-terminal amino-acid resiudes of CLPP increased reaction rate, which has been inferred to suggest increased the interaction with CLPP.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/08/18	2020/09/14	rogid:+SOis7raPEZqqeel6Y6dOWJcLj49606	rogid:Qd+ZdhUWoC42EGvaEkHbOo1H/40-2	rigid:O/WBuqgogQkjwHgsaIMYOflK7Pg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O76031	uniprotkb:Q16740-PRO_0000005516	intact:EBI-1052667|uniprotkb:A1L428|uniprotkb:A8K8F1|uniprotkb:Q9H4D9|uniprotkb:B9EGI8|ensembl:ENSP00000300107	intact:EBI-25815820	psi-mi:clpx_human(display_long)|uniprotkb:CLPX(gene name)|psi-mi:CLPX(display_short)	psi-mi:q16740-pro_0000005516(display_long)|uniprotkb:CLPP(gene name)|psi-mi:CLPP(display_short)|uniprotkb:Endopeptidase Clp(gene name synonym)	psi-mi:"MI:0435"(protease assay)	Kang et al. (2004)	pubmed:15522782|imex:IM-28396	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25815919|imex:IM-28396-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:1343"(enzyme regulator)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006651.2|ensembl:ENSG00000166855(gene)|ensembl:ENST00000300107(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009368"(endopeptidase Clp complex)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|go:"GO:0009841"(mitochondrial endopeptidase Clp complex)|mint:O76031|dip:DIP-50293N	intact:EBI-1056029(chain-parent)	-	-	chain-seq-start:57|chain-seq-end:277	figure legend:Fig. 6A, Table 2|comment:Removal of the 28 C-terminal amino-acid resiudes of CLPP increased reaction rate, which has been inferred to suggest increased the interaction with CLPP.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/08/18	2020/09/14	rogid:+SOis7raPEZqqeel6Y6dOWJcLj49606	rogid:NI9vS/tAKFh0iOSRNzRVlHUxUbc9606	rigid:O/WBuqgogQkjwHgsaIMYOflK7Pg	false	-	sufficient binding region:1-193|mutation decreasing interaction rate:1-1|mutation decreasing interaction strength:1-1	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-25815911	uniprotkb:Q16740-PRO_0000005516	-	intact:EBI-25815820	psi-mi:faphmalvpv(display_short)|psi-mi:EBI-25815911(display_long)	psi-mi:q16740-pro_0000005516(display_long)|uniprotkb:CLPP(gene name)|psi-mi:CLPP(display_short)|uniprotkb:Endopeptidase Clp(gene name synonym)	psi-mi:"MI:0435"(protease assay)	Kang et al. (2004)	pubmed:15522782|imex:IM-28396	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25828368|imex:IM-28396-5	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	intact:EBI-1056029(chain-parent)	-	-	chain-seq-start:57|chain-seq-end:277	figure legend:Table 2|comment:Removal of the 28 C-terminal amino-acid resiudes of CLPP increased reaction rate, which has been inferred to suggest increased the interaction with CLPP.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/08/18	2020/09/14	rogid:Qd+ZdhUWoC42EGvaEkHbOo1H/40-2	rogid:NI9vS/tAKFh0iOSRNzRVlHUxUbc9606	rigid:5Q1PIINp2ddTD1unFVm+dWbRJhQ	false	-	sufficient binding region:1-193	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0A6H1	intact:EBI-25815911	intact:EBI-547386|uniprotkb:P33138|uniprotkb:Q2MBY8|ensemblbacteria:AAC73541|ensemblbacteria:BAE76218	-	psi-mi:clpx_ecoli(display_long)|uniprotkb:clpX(gene name)|psi-mi:clpX(display_short)|uniprotkb:lopC(gene name synonym)|uniprotkb:b0438(locus name)|uniprotkb:JW0428(locus name)|uniprotkb:ATP-dependent unfoldase ClpX(gene name synonym)	psi-mi:faphmalvpv(display_short)|psi-mi:EBI-25815911(display_long)	psi-mi:"MI:0435"(protease assay)	Kang et al. (2004)	pubmed:15522782|imex:IM-28396	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25828468|imex:IM-28396-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:1343"(enzyme regulator)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	refseq:NP_414972.1|refseq:WP_000130305.1|ensemblbacteria:AAC73541(transcript)|ensemblbacteria:b0438(gene)|ensemblbacteria:BAE76218(gene)|ensemblbacteria:BAE76218(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030164"(protein denaturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|interpro:IPR038366|rcsb pdb:1OVX|rcsb pdb:2DS5|rcsb pdb:2DS6|rcsb pdb:2DS7|rcsb pdb:2DS8|rcsb pdb:3HTE|rcsb pdb:3HWS|rcsb pdb:4I34|rcsb pdb:4I4L|rcsb pdb:4I5O|rcsb pdb:4I63|rcsb pdb:4I81|rcsb pdb:4I9K|rcsb pdb:6PO1|rcsb pdb:6PO3|rcsb pdb:6POD|rcsb pdb:6POS|rcsb pdb:6PP5|rcsb pdb:6PP6|rcsb pdb:6PP7|rcsb pdb:6PP8|rcsb pdb:6PPE|rcsb pdb:6WR2|rcsb pdb:6WRF|rcsb pdb:6WSG|dip:DIP-35907N	-	-	-	-	figure legend:Fig. 6B,|comment:Removal of the 28 C-terminal amino-acid resiudes of CLPP increased reaction rate, which has been inferred to suggest increased the interaction with CLPP.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/08/18	2020/09/14	rogid:6//qYAydC2CE8MbKznReK0+ywDk83333	rogid:Qd+ZdhUWoC42EGvaEkHbOo1H/40-2	rigid:dRH6bmKpiSj8tex8k2g9ziPY8F4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0A6H1	uniprotkb:Q16740-PRO_0000005516	intact:EBI-547386|uniprotkb:P33138|uniprotkb:Q2MBY8|ensemblbacteria:AAC73541|ensemblbacteria:BAE76218	intact:EBI-25815820	psi-mi:clpx_ecoli(display_long)|uniprotkb:clpX(gene name)|psi-mi:clpX(display_short)|uniprotkb:lopC(gene name synonym)|uniprotkb:b0438(locus name)|uniprotkb:JW0428(locus name)|uniprotkb:ATP-dependent unfoldase ClpX(gene name synonym)	psi-mi:q16740-pro_0000005516(display_long)|uniprotkb:CLPP(gene name)|psi-mi:CLPP(display_short)|uniprotkb:Endopeptidase Clp(gene name synonym)	psi-mi:"MI:0435"(protease assay)	Kang et al. (2004)	pubmed:15522782|imex:IM-28396	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25828468|imex:IM-28396-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:1343"(enzyme regulator)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414972.1|refseq:WP_000130305.1|ensemblbacteria:AAC73541(transcript)|ensemblbacteria:b0438(gene)|ensemblbacteria:BAE76218(gene)|ensemblbacteria:BAE76218(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030164"(protein denaturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|interpro:IPR038366|rcsb pdb:1OVX|rcsb pdb:2DS5|rcsb pdb:2DS6|rcsb pdb:2DS7|rcsb pdb:2DS8|rcsb pdb:3HTE|rcsb pdb:3HWS|rcsb pdb:4I34|rcsb pdb:4I4L|rcsb pdb:4I5O|rcsb pdb:4I63|rcsb pdb:4I81|rcsb pdb:4I9K|rcsb pdb:6PO1|rcsb pdb:6PO3|rcsb pdb:6POD|rcsb pdb:6POS|rcsb pdb:6PP5|rcsb pdb:6PP6|rcsb pdb:6PP7|rcsb pdb:6PP8|rcsb pdb:6PPE|rcsb pdb:6WR2|rcsb pdb:6WRF|rcsb pdb:6WSG|dip:DIP-35907N	intact:EBI-1056029(chain-parent)	-	-	chain-seq-start:57|chain-seq-end:277	figure legend:Fig. 6B,|comment:Removal of the 28 C-terminal amino-acid resiudes of CLPP increased reaction rate, which has been inferred to suggest increased the interaction with CLPP.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/08/18	2020/09/14	rogid:6//qYAydC2CE8MbKznReK0+ywDk83333	rogid:NI9vS/tAKFh0iOSRNzRVlHUxUbc9606	rigid:dRH6bmKpiSj8tex8k2g9ziPY8F4	false	-	sufficient binding region:1-193	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0A6H1	intact:EBI-25815911	intact:EBI-547386|uniprotkb:P33138|uniprotkb:Q2MBY8|ensemblbacteria:AAC73541|ensemblbacteria:BAE76218	-	psi-mi:clpx_ecoli(display_long)|uniprotkb:clpX(gene name)|psi-mi:clpX(display_short)|uniprotkb:lopC(gene name synonym)|uniprotkb:b0438(locus name)|uniprotkb:JW0428(locus name)|uniprotkb:ATP-dependent unfoldase ClpX(gene name synonym)	psi-mi:faphmalvpv(display_short)|psi-mi:EBI-25815911(display_long)	psi-mi:"MI:0435"(protease assay)	Kang et al. (2004)	pubmed:15522782|imex:IM-28396	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25828484|imex:IM-28396-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:1343"(enzyme regulator)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	refseq:NP_414972.1|refseq:WP_000130305.1|ensemblbacteria:AAC73541(transcript)|ensemblbacteria:b0438(gene)|ensemblbacteria:BAE76218(gene)|ensemblbacteria:BAE76218(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030164"(protein denaturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|interpro:IPR038366|rcsb pdb:1OVX|rcsb pdb:2DS5|rcsb pdb:2DS6|rcsb pdb:2DS7|rcsb pdb:2DS8|rcsb pdb:3HTE|rcsb pdb:3HWS|rcsb pdb:4I34|rcsb pdb:4I4L|rcsb pdb:4I5O|rcsb pdb:4I63|rcsb pdb:4I81|rcsb pdb:4I9K|rcsb pdb:6PO1|rcsb pdb:6PO3|rcsb pdb:6POD|rcsb pdb:6POS|rcsb pdb:6PP5|rcsb pdb:6PP6|rcsb pdb:6PP7|rcsb pdb:6PP8|rcsb pdb:6PPE|rcsb pdb:6WR2|rcsb pdb:6WRF|rcsb pdb:6WSG|dip:DIP-35907N	-	-	-	-	figure legend:Fig. 6B,|comment:Removal of the 28 C-terminal amino-acid resiudes of CLPP increased reaction rate, which has been inferred to suggest increased the interaction with CLPP.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/08/18	2020/09/14	rogid:6//qYAydC2CE8MbKznReK0+ywDk83333	rogid:Qd+ZdhUWoC42EGvaEkHbOo1H/40-2	rigid:m3fuIiMOy+oZHgyROmjAOLr7bBg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0A6H1	uniprotkb:P0A6G7-PRO_0000179551	intact:EBI-547386|uniprotkb:P33138|uniprotkb:Q2MBY8|ensemblbacteria:AAC73541|ensemblbacteria:BAE76218	intact:EBI-25828476	psi-mi:clpx_ecoli(display_long)|uniprotkb:clpX(gene name)|psi-mi:clpX(display_short)|uniprotkb:lopC(gene name synonym)|uniprotkb:b0438(locus name)|uniprotkb:JW0428(locus name)|uniprotkb:ATP-dependent unfoldase ClpX(gene name synonym)	psi-mi:p0a6g7-pro_0000179551(display_long)|uniprotkb:clpP(gene name)|psi-mi:clpP(display_short)|uniprotkb:lopP(gene name synonym)|uniprotkb:b0437(locus name)|uniprotkb:JW0427(locus name)|uniprotkb:Caseinolytic protease(gene name synonym)|uniprotkb:Endopeptidase Clp(gene name synonym)|uniprotkb:Heat shock protein F21.5(gene name synonym)|uniprotkb:Protease Ti(gene name synonym)	psi-mi:"MI:0435"(protease assay)	Kang et al. (2004)	pubmed:15522782|imex:IM-28396	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0570"(protein cleavage)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25828484|imex:IM-28396-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:1343"(enzyme regulator)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414972.1|refseq:WP_000130305.1|ensemblbacteria:AAC73541(transcript)|ensemblbacteria:b0438(gene)|ensemblbacteria:BAE76218(gene)|ensemblbacteria:BAE76218(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009376"(HslUV protease complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030164"(protein denaturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|interpro:IPR038366|rcsb pdb:1OVX|rcsb pdb:2DS5|rcsb pdb:2DS6|rcsb pdb:2DS7|rcsb pdb:2DS8|rcsb pdb:3HTE|rcsb pdb:3HWS|rcsb pdb:4I34|rcsb pdb:4I4L|rcsb pdb:4I5O|rcsb pdb:4I63|rcsb pdb:4I81|rcsb pdb:4I9K|rcsb pdb:6PO1|rcsb pdb:6PO3|rcsb pdb:6POD|rcsb pdb:6POS|rcsb pdb:6PP5|rcsb pdb:6PP6|rcsb pdb:6PP7|rcsb pdb:6PP8|rcsb pdb:6PPE|rcsb pdb:6WR2|rcsb pdb:6WRF|rcsb pdb:6WSG|dip:DIP-35907N	intact:EBI-370625(chain-parent)	-	-	chain-seq-start:15|chain-seq-end:207	figure legend:Fig. 6B,|comment:Removal of the 28 C-terminal amino-acid resiudes of CLPP increased reaction rate, which has been inferred to suggest increased the interaction with CLPP.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/08/18	2020/09/14	rogid:6//qYAydC2CE8MbKznReK0+ywDk83333	rogid:hKZh56zK5/RNOHGdIKsiFQR/gLQ83333	rigid:m3fuIiMOy+oZHgyROmjAOLr7bBg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O76031	uniprotkb:Q16740-PRO_0000005516	intact:EBI-1052667|uniprotkb:A1L428|uniprotkb:A8K8F1|uniprotkb:Q9H4D9|uniprotkb:B9EGI8|ensembl:ENSP00000300107	intact:EBI-25815820	psi-mi:clpx_human(display_long)|uniprotkb:CLPX(gene name)|psi-mi:CLPX(display_short)	psi-mi:q16740-pro_0000005516(display_long)|uniprotkb:CLPP(gene name)|psi-mi:CLPP(display_short)|uniprotkb:Endopeptidase Clp(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Kang et al. (2004)	pubmed:15522782|imex:IM-28396	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25828568|imex:IM-28396-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006651.2|ensembl:ENSG00000166855(gene)|ensembl:ENST00000300107(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009368"(endopeptidase Clp complex)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|go:"GO:0009841"(mitochondrial endopeptidase Clp complex)|mint:O76031|dip:DIP-50293N	intact:EBI-1056029(chain-parent)	-	-	chain-seq-start:57|chain-seq-end:277	figure legend:Fig. 7|comment:Removal of the 28 C-terminal amino-acid resiudes of CLPP increased reaction rate, which has been inferred to suggest increased the interaction with CLPP.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/08/18	2020/09/14	rogid:+SOis7raPEZqqeel6Y6dOWJcLj49606	rogid:NI9vS/tAKFh0iOSRNzRVlHUxUbc9606	rigid:weRad9bQm+/YhDPw3IICWfhpjB8	false	-	mutation decreasing interaction rate:1-1|necessary binding region:1-3|mutation decreasing interaction strength:1-1	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)