#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q17551	uniprotkb:G5ECU1	intact:EBI-6920110|ensemblmetazoa:C01B7.6.1	intact:EBI-323117|uniprotkb:Q8WSZ9|ensemblmetazoa:F46A9.5.1|ensemblmetazoa:F46A9.5.2|ensemblmetazoa:F46A9.5.3|ensemblmetazoa:F46A9.5.4	psi-mi:rpm1_caeel(display_long)|uniprotkb:rpm-1(gene name)|psi-mi:rpm-1(display_short)|uniprotkb:syd-3(gene name synonym)|uniprotkb:Pam/highwire/rpm-1 protein(gene name synonym)|uniprotkb:Regulator of presynaptic morphology protein 1(gene name synonym)|uniprotkb:Synapse defective protein 3(gene name synonym)|uniprotkb:C01B7.6(orf name)	psi-mi:skr1_caeel(display_long)|uniprotkb:skr-1(gene name)|psi-mi:skr-1(display_short)|uniprotkb:F46A9.5(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liao et al. (2004)	pubmed:15208641|imex:IM-27896	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25565118|imex:IM-27896-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:C01B7.6.1(transcript)|ensemblmetazoa:WBGene00004457(gene)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010171"(body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0040011"(locomotion)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045202"(synapse)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0048692"(negative regulation of axon extension involved in regeneration)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1905489"(regulation of sensory neuron axon guidance)|go:"GO:1905490"(negative regulation of sensory neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:1905608"(positive regulation of presynapse assembly)|go:"GO:1905812"(regulation of motor neuron axon guidance)|go:"GO:1905815"(regulation of dorsal/ventral axon guidance)|go:"GO:1905868"(regulation of 3'-UTR-mediated mRNA stabilization)|go:"GO:1905869"(negative regulation of 3'-UTR-mediated mRNA stabilization)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR038648|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR012983(PHR)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_505267.1|wormbase:C01B7.6	interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492513.1|uniprotkb:Q93647(uniprot-removed-ac)|ensemblmetazoa:F46A9.5.1(transcript)|ensemblmetazoa:F46A9.5.2(transcript)|ensemblmetazoa:F46A9.5.3(transcript)|ensemblmetazoa:F46A9.5.4(transcript)|ensemblmetazoa:WBGene00004807(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046660"(female sex differentiation)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|wormbase:F46A9.5|reactome:R-CEL-68949|reactome:R-CEL-983168|reactome:R-CEL-69231|reactome:R-CEL-8951664|interpro:IPR036296|reactome:R-CEL-8939902|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-8854050|reactome:R-CEL-917937	-	-	-	figure legend:2g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2020/04/09	2020/04/17	rogid:X493vwFdULZd8T/quxnGHUxjiGI6239	rogid:KxYt2Ajt5MxBSiSlrJPfBp7IBvc6239	rigid:ROIwr4me+OGzVz2Gu145N2g4Wd0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q17551	uniprotkb:Q17389	intact:EBI-6920110|ensemblmetazoa:C01B7.6.1	intact:EBI-12687470|ensemblmetazoa:D2045.6.1|uniprotkb:Q18985	psi-mi:rpm1_caeel(display_long)|uniprotkb:rpm-1(gene name)|psi-mi:rpm-1(display_short)|uniprotkb:syd-3(gene name synonym)|uniprotkb:Pam/highwire/rpm-1 protein(gene name synonym)|uniprotkb:Regulator of presynaptic morphology protein 1(gene name synonym)|uniprotkb:Synapse defective protein 3(gene name synonym)|uniprotkb:C01B7.6(orf name)	psi-mi:cul1_caeel(display_long)|uniprotkb:cul-1(gene name)|psi-mi:cul-1(display_short)|uniprotkb:lin-19(gene name synonym)|uniprotkb:D2045.6(orf name)|uniprotkb:Abnormal cell lineage protein 19(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liao et al. (2004)	pubmed:15208641|imex:IM-27896	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25565118|imex:IM-27896-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:C01B7.6.1(transcript)|ensemblmetazoa:WBGene00004457(gene)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010171"(body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0040011"(locomotion)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045202"(synapse)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0048692"(negative regulation of axon extension involved in regeneration)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1905489"(regulation of sensory neuron axon guidance)|go:"GO:1905490"(negative regulation of sensory neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:1905608"(positive regulation of presynapse assembly)|go:"GO:1905812"(regulation of motor neuron axon guidance)|go:"GO:1905815"(regulation of dorsal/ventral axon guidance)|go:"GO:1905868"(regulation of 3'-UTR-mediated mRNA stabilization)|go:"GO:1905869"(negative regulation of 3'-UTR-mediated mRNA stabilization)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR038648|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR012983(PHR)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_505267.1|wormbase:C01B7.6	ensemblmetazoa:D2045.6.1(transcript)|ensemblmetazoa:WBGene00000836(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042594"(response to starvation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051301"(cell division)|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-68949|reactome:R-CEL-69231|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8951664|reactome:R-CEL-917937|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_499309.1|wormbase:D2045.6|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:2g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2020/04/09	2020/04/17	rogid:X493vwFdULZd8T/quxnGHUxjiGI6239	rogid:Tpix3oCNQ1diY1WVa4IQkRzudzg6239	rigid:ROIwr4me+OGzVz2Gu145N2g4Wd0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q17551	uniprotkb:Q18223	intact:EBI-6920110|ensemblmetazoa:C01B7.6.1	intact:EBI-2003744|ensemblmetazoa:C26E6.5.1	psi-mi:rpm1_caeel(display_long)|uniprotkb:rpm-1(gene name)|psi-mi:rpm-1(display_short)|uniprotkb:syd-3(gene name synonym)|uniprotkb:Pam/highwire/rpm-1 protein(gene name synonym)|uniprotkb:Regulator of presynaptic morphology protein 1(gene name synonym)|uniprotkb:Synapse defective protein 3(gene name synonym)|uniprotkb:C01B7.6(orf name)	psi-mi:fbsp1_caeel(display_long)|uniprotkb:fsn-1(gene name)|psi-mi:fsn-1(display_short)|uniprotkb:F-box synaptic protein 1(gene name synonym)|uniprotkb:C26E6.5(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liao et al. (2004)	pubmed:15208641|imex:IM-27896	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25565118|imex:IM-27896-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:C01B7.6.1(transcript)|ensemblmetazoa:WBGene00004457(gene)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010171"(body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0040011"(locomotion)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045202"(synapse)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0048692"(negative regulation of axon extension involved in regeneration)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1905489"(regulation of sensory neuron axon guidance)|go:"GO:1905490"(negative regulation of sensory neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:1905608"(positive regulation of presynapse assembly)|go:"GO:1905812"(regulation of motor neuron axon guidance)|go:"GO:1905815"(regulation of dorsal/ventral axon guidance)|go:"GO:1905868"(regulation of 3'-UTR-mediated mRNA stabilization)|go:"GO:1905869"(negative regulation of 3'-UTR-mediated mRNA stabilization)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR038648|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR012983(PHR)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_505267.1|wormbase:C01B7.6	refseq:NP_498046.1|wormbase:C26E6.5|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035784|interpro:IPR036047|interpro:IPR043136|ensemblmetazoa:C26E6.5.1(transcript)|ensemblmetazoa:WBGene00001499(gene)|go:"GO:0002020"(protease binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0040024"(dauer larval development)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060386"(synapse assembly involved in innervation)|go:"GO:0098793"(presynapse)|go:"GO:1900073"(regulation of neuromuscular synaptic transmission)|go:"GO:1900075"(positive regulation of neuromuscular synaptic transmission)|go:"GO:1900182"(positive regulation of protein localization to nucleus)	-	-	-	figure legend:2g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2020/04/09	2020/04/17	rogid:X493vwFdULZd8T/quxnGHUxjiGI6239	rogid:Voig45zw30LCvvEucQt9DkmQFnI6239	rigid:ROIwr4me+OGzVz2Gu145N2g4Wd0	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q18223	uniprotkb:G5ECU1	intact:EBI-2003744|ensemblmetazoa:C26E6.5.1	intact:EBI-323117|uniprotkb:Q8WSZ9|ensemblmetazoa:F46A9.5.1|ensemblmetazoa:F46A9.5.2|ensemblmetazoa:F46A9.5.3|ensemblmetazoa:F46A9.5.4	psi-mi:fbsp1_caeel(display_long)|uniprotkb:fsn-1(gene name)|psi-mi:fsn-1(display_short)|uniprotkb:F-box synaptic protein 1(gene name synonym)|uniprotkb:C26E6.5(orf name)	psi-mi:skr1_caeel(display_long)|uniprotkb:skr-1(gene name)|psi-mi:skr-1(display_short)|uniprotkb:F46A9.5(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liao et al. (2004)	pubmed:15208641|imex:IM-27896	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25565124|imex:IM-27896-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_498046.1|wormbase:C26E6.5|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035784|interpro:IPR036047|interpro:IPR043136|ensemblmetazoa:C26E6.5.1(transcript)|ensemblmetazoa:WBGene00001499(gene)|go:"GO:0002020"(protease binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0040024"(dauer larval development)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060386"(synapse assembly involved in innervation)|go:"GO:0098793"(presynapse)|go:"GO:1900073"(regulation of neuromuscular synaptic transmission)|go:"GO:1900075"(positive regulation of neuromuscular synaptic transmission)|go:"GO:1900182"(positive regulation of protein localization to nucleus)	interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492513.1|uniprotkb:Q93647(uniprot-removed-ac)|ensemblmetazoa:F46A9.5.1(transcript)|ensemblmetazoa:F46A9.5.2(transcript)|ensemblmetazoa:F46A9.5.3(transcript)|ensemblmetazoa:F46A9.5.4(transcript)|ensemblmetazoa:WBGene00004807(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046660"(female sex differentiation)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|wormbase:F46A9.5|reactome:R-CEL-68949|reactome:R-CEL-983168|reactome:R-CEL-69231|reactome:R-CEL-8951664|interpro:IPR036296|reactome:R-CEL-8939902|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-8854050|reactome:R-CEL-917937	-	-	-	figure legend:2g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2020/04/09	2020/04/17	rogid:Voig45zw30LCvvEucQt9DkmQFnI6239	rogid:KxYt2Ajt5MxBSiSlrJPfBp7IBvc6239	rigid:ROIwr4me+OGzVz2Gu145N2g4Wd0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q18223	uniprotkb:Q17389	intact:EBI-2003744|ensemblmetazoa:C26E6.5.1	intact:EBI-12687470|ensemblmetazoa:D2045.6.1|uniprotkb:Q18985	psi-mi:fbsp1_caeel(display_long)|uniprotkb:fsn-1(gene name)|psi-mi:fsn-1(display_short)|uniprotkb:F-box synaptic protein 1(gene name synonym)|uniprotkb:C26E6.5(orf name)	psi-mi:cul1_caeel(display_long)|uniprotkb:cul-1(gene name)|psi-mi:cul-1(display_short)|uniprotkb:lin-19(gene name synonym)|uniprotkb:D2045.6(orf name)|uniprotkb:Abnormal cell lineage protein 19(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liao et al. (2004)	pubmed:15208641|imex:IM-27896	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25565124|imex:IM-27896-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_498046.1|wormbase:C26E6.5|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035784|interpro:IPR036047|interpro:IPR043136|ensemblmetazoa:C26E6.5.1(transcript)|ensemblmetazoa:WBGene00001499(gene)|go:"GO:0002020"(protease binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0040024"(dauer larval development)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060386"(synapse assembly involved in innervation)|go:"GO:0098793"(presynapse)|go:"GO:1900073"(regulation of neuromuscular synaptic transmission)|go:"GO:1900075"(positive regulation of neuromuscular synaptic transmission)|go:"GO:1900182"(positive regulation of protein localization to nucleus)	ensemblmetazoa:D2045.6.1(transcript)|ensemblmetazoa:WBGene00000836(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042594"(response to starvation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0051301"(cell division)|reactome:R-CEL-983168|reactome:R-CEL-187577|reactome:R-CEL-195253|reactome:R-CEL-68949|reactome:R-CEL-69231|reactome:R-CEL-8854050|reactome:R-CEL-8939902|reactome:R-CEL-8951664|reactome:R-CEL-917937|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_499309.1|wormbase:D2045.6|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:2g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2020/04/09	2020/04/17	rogid:Voig45zw30LCvvEucQt9DkmQFnI6239	rogid:Tpix3oCNQ1diY1WVa4IQkRzudzg6239	rigid:ROIwr4me+OGzVz2Gu145N2g4Wd0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q18223	uniprotkb:Q17551	intact:EBI-2003744|ensemblmetazoa:C26E6.5.1	intact:EBI-6920110|ensemblmetazoa:C01B7.6.1	psi-mi:fbsp1_caeel(display_long)|uniprotkb:fsn-1(gene name)|psi-mi:fsn-1(display_short)|uniprotkb:F-box synaptic protein 1(gene name synonym)|uniprotkb:C26E6.5(orf name)	psi-mi:rpm1_caeel(display_long)|uniprotkb:rpm-1(gene name)|psi-mi:rpm-1(display_short)|uniprotkb:syd-3(gene name synonym)|uniprotkb:Pam/highwire/rpm-1 protein(gene name synonym)|uniprotkb:Regulator of presynaptic morphology protein 1(gene name synonym)|uniprotkb:Synapse defective protein 3(gene name synonym)|uniprotkb:C01B7.6(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liao et al. (2004)	pubmed:15208641|imex:IM-27896	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25565124|imex:IM-27896-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_498046.1|wormbase:C26E6.5|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035784|interpro:IPR036047|interpro:IPR043136|ensemblmetazoa:C26E6.5.1(transcript)|ensemblmetazoa:WBGene00001499(gene)|go:"GO:0002020"(protease binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0040024"(dauer larval development)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060386"(synapse assembly involved in innervation)|go:"GO:0098793"(presynapse)|go:"GO:1900073"(regulation of neuromuscular synaptic transmission)|go:"GO:1900075"(positive regulation of neuromuscular synaptic transmission)|go:"GO:1900182"(positive regulation of protein localization to nucleus)	ensemblmetazoa:C01B7.6.1(transcript)|ensemblmetazoa:WBGene00004457(gene)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010171"(body morphogenesis)|go:"GO:0018991"(oviposition)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0036062"(presynaptic periactive zone)|go:"GO:0040011"(locomotion)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045202"(synapse)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0048692"(negative regulation of axon extension involved in regeneration)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1905489"(regulation of sensory neuron axon guidance)|go:"GO:1905490"(negative regulation of sensory neuron axon guidance)|go:"GO:0030424"(axon)|go:"GO:1905608"(positive regulation of presynapse assembly)|go:"GO:1905812"(regulation of motor neuron axon guidance)|go:"GO:1905815"(regulation of dorsal/ventral axon guidance)|go:"GO:1905868"(regulation of 3'-UTR-mediated mRNA stabilization)|go:"GO:1905869"(negative regulation of 3'-UTR-mediated mRNA stabilization)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR038648|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR012983(PHR)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_505267.1|wormbase:C01B7.6	-	-	-	figure legend:2g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2020/04/09	2020/04/17	rogid:Voig45zw30LCvvEucQt9DkmQFnI6239	rogid:X493vwFdULZd8T/quxnGHUxjiGI6239	rigid:ROIwr4me+OGzVz2Gu145N2g4Wd0	false	-	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O76411	uniprotkb:Q18223	intact:EBI-25565695|ensemblmetazoa:T10H9.2.1	intact:EBI-2003744|ensemblmetazoa:C26E6.5.1	psi-mi:scd2_caeel(display_long)|uniprotkb:scd-2(gene name)|psi-mi:scd-2(display_short)|uniprotkb:Suppressor of constitutive dauer formation protein 2(gene name synonym)|uniprotkb:T10H9.2(orf name)	psi-mi:fbsp1_caeel(display_long)|uniprotkb:fsn-1(gene name)|psi-mi:fsn-1(display_short)|uniprotkb:F-box synaptic protein 1(gene name synonym)|uniprotkb:C26E6.5(orf name)	psi-mi:"MI:0096"(pull down)	Liao et al. (2004)	pubmed:15208641|imex:IM-27896	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25565732|imex:IM-27896-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:T10H9.2.1(transcript)|ensemblmetazoa:WBGene00004740(gene)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0007606"(sensory perception of chemical stimulus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0040024"(dauer larval development)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0050893"(sensory processing)|refseq:NP_504685.3|wormbase:T10H9.2|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR011009(Protein kinase-like)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR000998(MAM)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635	refseq:NP_498046.1|wormbase:C26E6.5|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035784|interpro:IPR036047|interpro:IPR043136|ensemblmetazoa:C26E6.5.1(transcript)|ensemblmetazoa:WBGene00001499(gene)|go:"GO:0002020"(protease binding)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008582"(regulation of synaptic assembly at neuromuscular junction)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0040024"(dauer larval development)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060386"(synapse assembly involved in innervation)|go:"GO:0098793"(presynapse)|go:"GO:1900073"(regulation of neuromuscular synaptic transmission)|go:"GO:1900075"(positive regulation of neuromuscular synaptic transmission)|go:"GO:1900182"(positive regulation of protein localization to nucleus)	-	-	-	figure legend:3j|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/04/09	2020/04/17	rogid:eRahnkJM4YdxE7xwdoDo5Vouq9M6239	rogid:Voig45zw30LCvvEucQt9DkmQFnI6239	rigid:twbotlHi/pAIzYvxdpgpg+rRv18	false	sufficient binding region:964-1414|glutathione s tranferase tag:?-?	sufficient binding region:85-332|his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)