#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P59635	uniprotkb:P59632	intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17	intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5	psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name)	psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tan et al. (2004)	pubmed:15194747|imex:IM-28083	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25646931|imex:IM-28083-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1	reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2	-	-	-	figure legend:Fig. 6a panel 4|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/06/15	2020/06/15	rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009	rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009	rigid:Q8Xp3PNgizV2YQHv5YX1F/ojDL4	false	ha tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P59637	uniprotkb:P59632	intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8	intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5	psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name)	psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tan et al. (2004)	pubmed:15194747|imex:IM-28083	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25647200|imex:IM-28083-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1	reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2	-	-	-	figure legend:Fig. 6a panel 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/06/15	2020/06/15	rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009	rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009	rigid:j0i7A3uUDMh6QR/s/aAkOcDchuU	false	ha tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P59596	uniprotkb:P59632	intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12	intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5	psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name)	psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tan et al. (2004)	pubmed:15194747|imex:IM-28083	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25647353|imex:IM-28083-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1	reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2	-	-	-	figure legend:Fig. 6a panel 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/06/15	2020/06/15	rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009	rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009	rigid:fOf/jWaqsw18fUwCtjLyicIDyXw	false	ha tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P59594	uniprotkb:P59632	intact:EBI-15582614|intact:EBI-16063777|uniprotkb:Q6QU82|uniprotkb:Q7T696|uniprotkb:Q7TA19|uniprotkb:Q7TFA2|uniprotkb:Q7TFB1|uniprotkb:Q80BV6	intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5	psi-mi:spike_sars(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name)	psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tan et al. (2004)	pubmed:15194747|imex:IM-28083	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25647496|imex:IM-28083-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR032500|interpro:IPR036326|interpro:IPR042578|interpro:IPR043002|interpro:IPR043473|interpro:IPR043607|interpro:IPR044341|interpro:IPR044370|interpro:IPR044873|interpro:IPR044874|rcsb pdb:1Q4Z|rcsb pdb:1T7G|rcsb pdb:1U4K|rcsb pdb:1WNC|rcsb pdb:1WYY|rcsb pdb:1XJP|rcsb pdb:1ZV7|rcsb pdb:1ZV8|rcsb pdb:1ZVB|rcsb pdb:2AJF|rcsb pdb:2BEQ|rcsb pdb:2BEZ|rcsb pdb:2DD8|rcsb pdb:2FXP|rcsb pdb:2GHV|rcsb pdb:2GHW|rcsb pdb:2RUM|rcsb pdb:2RUN|rcsb pdb:2RUO|rcsb pdb:3BGF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:5WRG|rcsb pdb:5X4S|rcsb pdb:5X58|rcsb pdb:5X5B|rcsb pdb:5XJK|rcsb pdb:5XLR|rcsb pdb:5ZVM|rcsb pdb:6ACC|rcsb pdb:6ACD|rcsb pdb:6ACG|rcsb pdb:6ACK|rcsb pdb:6CRV|rcsb pdb:6CRW|rcsb pdb:6CRX|rcsb pdb:6CRZ|rcsb pdb:6CS0|rcsb pdb:6CS1|rcsb pdb:6CS2|rcsb pdb:6M3W|rcsb pdb:6NB6|rcsb pdb:6NB7|rcsb pdb:6VW1|rcsb pdb:6WAQ|rcsb pdb:7JN5|rcsb pdb:6ACJ|dip:DIP-29105N|reactome:R-HSA-9679509|reactome:R-HSA-9683686|reactome:R-HSA-9683701|refseq:NP_828851.1|reactome:R-HSA-9678110	reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2	-	-	-	figure legend:Fig. 6b|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/06/15	2020/06/15	rogid:H4uZUhfNNQNcF4O+7CmC50IoAi8694009	rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009	rigid:MWjTe2+3xlmxNfoo4kjqmm0yN/0	false	-	myc tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)