#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O00187-2	uniprotkb:O00187-2	intact:EBI-26356134|ensembl:ENSP00000383691	intact:EBI-26356134|ensembl:ENSP00000383691	psi-mi:o00187-2(display_long)|uniprotkb:MASP2(gene name)|psi-mi:MASP2(display_short)|uniprotkb:MBL-associated serine protease 2(gene name synonym)|uniprotkb:Mannose-binding protein-associated serine protease 2(gene name synonym)|uniprotkb:MAp19(isoform synonym)|uniprotkb:Small MBL-associated protein(isoform synonym)|uniprotkb:sMAP(isoform synonym)	psi-mi:o00187-2(display_long)|uniprotkb:MASP2(gene name)|psi-mi:MASP2(display_short)|uniprotkb:MBL-associated serine protease 2(gene name synonym)|uniprotkb:Mannose-binding protein-associated serine protease 2(gene name synonym)|uniprotkb:MAp19(isoform synonym)|uniprotkb:Small MBL-associated protein(isoform synonym)|uniprotkb:sMAP(isoform synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Gregory et al. (2004)	pubmed:15117939|imex:IM-28364	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26356486|wwpdb:1szb|imex:IM-28364-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000009724(gene)|ensembl:ENST00000400898(transcript)|intact:EBI-7965040(isoform-parent)	ensembl:ENSG00000009724(gene)|ensembl:ENST00000400898(transcript)|intact:EBI-7965040(isoform-parent)	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/24	2020/09/24	rogid:HFrZYSDiESe89IQqgChsunpvyTc9606	rogid:HFrZYSDiESe89IQqgChsunpvyTc9606	rigid:ACWRYZ6AqzQ1eMD2VFjln7AQNes	false	sufficient binding region:16-185	sufficient binding region:16-185	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11226	uniprotkb:O00187-2	intact:EBI-5325353|ensembl:ENSP00000363079|ensembl:ENSP00000502615|ensembl:ENSP00000502789|uniprotkb:Q4VB12|uniprotkb:Q4VB13|uniprotkb:Q86SI4|uniprotkb:Q96KE4|uniprotkb:Q96TF7|uniprotkb:Q96TF8|uniprotkb:Q96TF9|uniprotkb:Q4VB14|uniprotkb:Q5SQS3	intact:EBI-26356134|ensembl:ENSP00000383691	psi-mi:mbl2_human(display_long)|uniprotkb:MBL2(gene name)|psi-mi:MBL2(display_short)|uniprotkb:COLEC1(gene name synonym)|uniprotkb:MBL(gene name synonym)|uniprotkb:Collectin-1(gene name synonym)|uniprotkb:MBP1(gene name synonym)|uniprotkb:Mannan-binding protein(gene name synonym)|uniprotkb:Mannose-binding lectin(gene name synonym)	psi-mi:o00187-2(display_long)|uniprotkb:MASP2(gene name)|psi-mi:MASP2(display_short)|uniprotkb:MBL-associated serine protease 2(gene name synonym)|uniprotkb:Mannose-binding protein-associated serine protease 2(gene name synonym)|uniprotkb:MAp19(isoform synonym)|uniprotkb:Small MBL-associated protein(isoform synonym)|uniprotkb:sMAP(isoform synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Gregory et al. (2004)	pubmed:15117939|imex:IM-28364	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26356518|imex:IM-28364-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165471(gene)|ensembl:ENST00000373968(transcript)|ensembl:ENST00000674931(transcript)|ensembl:ENST00000675947(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008228"(opsonization)|go:"GO:0009986"(cell surface)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001304(C-type lectin)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016186(C-type lectin-like)|refseq:XP_011538118.1|interpro:IPR018378|interpro:IPR033990|interpro:IPR037570|rcsb pdb:1HUP|interpro:IPR016187(C-type lectin fold)|reactome:R-HSA-166662|reactome:R-HSA-166663|refseq:NP_000233.1|refseq:XP_006717924.1|dip:DIP-61381N	ensembl:ENSG00000009724(gene)|ensembl:ENST00000400898(transcript)|intact:EBI-7965040(isoform-parent)	-	-	-	figure legend:Fig. 4A Table II|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.05x10^-8(molar)	2020/09/24	2020/09/24	rogid:uo0RM88uw3otObIVnOhUcOfW8yo9606	rogid:HFrZYSDiESe89IQqgChsunpvyTc9606	rigid:AmtgOwl0SEIqQeetM0ct7qu3S6o	false	-	mutation with no effect:56-56|mutation disrupting interaction strength:121-121|mutation with no effect:96-96|sufficient binding region:16-185|mutation decreasing interaction strength:124-124|mutation decreasing interaction strength:148-148|mutation with no effect:70-70|mutation with no effect:73-73|mutation disrupting interaction strength:74-74|mutation decreasing interaction strength:75-75|mutation with no effect:93-93|mutation disrupting interaction strength:120-120|mutation decreasing interaction strength:98-98	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15485	uniprotkb:O00187-2	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-26356134|ensembl:ENSP00000383691	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:o00187-2(display_long)|uniprotkb:MASP2(gene name)|psi-mi:MASP2(display_short)|uniprotkb:MBL-associated serine protease 2(gene name synonym)|uniprotkb:Mannose-binding protein-associated serine protease 2(gene name synonym)|uniprotkb:MAp19(isoform synonym)|uniprotkb:Small MBL-associated protein(isoform synonym)|uniprotkb:sMAP(isoform synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Gregory et al. (2004)	pubmed:15117939|imex:IM-28364	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26356980|imex:IM-28364-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	ensembl:ENSG00000009724(gene)|ensembl:ENST00000400898(transcript)|intact:EBI-7965040(isoform-parent)	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:Fig. 4B Table II|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:1.04x10^-8(molar)	2020/09/24	2020/09/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:HFrZYSDiESe89IQqgChsunpvyTc9606	rigid:9j3HZ+aKwdu+MyZzmnwajVuSJAE	false	-	mutation with no effect:56-56|mutation disrupting interaction strength:121-121|mutation with no effect:96-96|sufficient binding region:16-185|mutation with no effect:124-124|mutation decreasing interaction strength:148-148|mutation with no effect:70-70|mutation with no effect:73-73|mutation disrupting interaction strength:74-74|mutation with no effect:93-93|mutation decreasing interaction strength:98-98|mutation decreasing interaction strength:75-75|mutation disrupting interaction strength:120-120	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)