#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P59595 uniprotkb:P59595 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Surjit et al. (2004) pubmed:15094372|imex:IM-27913 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25564790|imex:IM-27913-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid figure legend:Fig. 1, Fig. 2, Fig. 4|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/04/15 2020/04/15 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rigid:nfUtR/Mag3BPyE3iFX33w2BEkZs false sufficient binding region:210-422|necessary binding region:277-422 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12904 uniprotkb:P06782 intact:EBI-17537|ensemblfungi:YGL115W|uniprotkb:D6VU32 intact:EBI-17516|uniprotkb:D6VTA0|ensemblfungi:YDR477W psi-mi:aakg_yeast(display_long)|uniprotkb:SNF4(gene name)|psi-mi:SNF4(display_short)|uniprotkb:CAT3(gene name synonym)|uniprotkb:Regulatory protein CAT3(gene name synonym)|uniprotkb:SCI1(gene name synonym)|uniprotkb:Sucrose non-fermenting protein 4(gene name synonym)|uniprotkb:YGL115W(locus name) psi-mi:snf1_yeast(display_long)|uniprotkb:SNF1(gene name)|psi-mi:SNF1(display_short)|uniprotkb:CAT1(gene name synonym)|uniprotkb:CCR1(gene name synonym)|uniprotkb:GLC2(gene name synonym)|uniprotkb:PAS14(gene name synonym)|uniprotkb:Sucrose nonfermentating protein 1(gene name synonym)|uniprotkb:D8035.20(orf name)|uniprotkb:YDR477W(locus name) psi-mi:"MI:0018"(two hybrid) Surjit et al. (2004) pubmed:15094372|imex:IM-27913 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25564794|imex:IM-27913-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|ensemblfungi:YGL115W(gene)|ensemblfungi:YGL115W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|refseq:NP_011400.1|sgd:S000003083|go:"GO:0007031"(peroxisome organization)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|rcsb pdb:2NYC|rcsb pdb:2NYE|rcsb pdb:2QLV|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|dip:DIP-592N|mint:P12904 refseq:NP_010765.3|sgd:S000002885|ensemblfungi:YDR477W(gene)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0071940"(fungal-type cell wall assembly)|go:"GO:0090606"(single-species surface biofilm formation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900436"(positive regulation of filamentous growth of a population of unicellular organisms in response to starvation)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013896(Ubiquitin-associated region 2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR032270|rcsb pdb:2FH9|rcsb pdb:2QLV|rcsb pdb:3DAE|rcsb pdb:3HYH|rcsb pdb:3MN3|rcsb pdb:3T4N|rcsb pdb:3TDH|rcsb pdb:3TE5|reactome:R-SCE-1632852|reactome:R-SCE-163680|reactome:R-SCE-200425|reactome:R-SCE-380972|ensemblfungi:YDR477W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000144"(cellular bud neck septin ring)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0007155"(cell adhesion)|go:"GO:0016239"(positive regulation of macroautophagy)|dip:DIP-18N|mint:P06782 - crc64:51B387E346EE9561 crc64:F5C63565C986C4E3 figure legend:Fig. 1, Fig. 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/04/15 2020/04/15 rogid:dYtx5LQZtt2QZX/VelN4akMH7KA559292 rogid:O/SAW1kJE3fpoXPHGLG01i9RePs559292 rigid:4MHnCvJEe/pauqdj+JsPSZ8Bj+o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P59595 uniprotkb:P59595 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Surjit et al. (2004) pubmed:15094372|imex:IM-27913 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25564823|imex:IM-27913-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid figure legend:Fig. 3 lane 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2020/04/15 2020/04/15 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rigid:nfUtR/Mag3BPyE3iFX33w2BEkZs false ha tag:n-n myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)