#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:P0C6X7-PRO_0000037316 intact:EBI-25475825 intact:EBI-25475825 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0114"(x-ray crystallography) Sutton et al. (2004) pubmed:14962394|imex:IM-27958 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25595275|imex:IM-27958-1|wwpdb:1UW7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) intact:EBI-7843867(chain-parent) - chain-seq-start:4118|chain-seq-end:4230 chain-seq-start:4118|chain-seq-end:4230 figure legend:Table 4|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/06 2020/05/06 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rigid:2/6i9UZxwEXjOQHa7xe1bpujt/U false his tag:n-n|tag:n-n his tag:n-n|tag:n-n 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:P0C6X7-PRO_0000037316 intact:EBI-25475825 intact:EBI-25475825 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0038"(dynamic light scattering) Sutton et al. (2004) pubmed:14962394|imex:IM-27958 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25595332|imex:IM-27958-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) intact:EBI-7843867(chain-parent) - chain-seq-start:4118|chain-seq-end:4230 chain-seq-start:4118|chain-seq-end:4230 figure legend:Figure 4A|comment:It is not clear from the text if the N-terminal tags have been removed for DLS measurements, or not.|comment:"For concentrations above 1.5mg/ml the Stokes’radius of approximately 2.1 nm (Figure 4A), is in close agreement with the calculated radius of 1.9 nm for a dimer."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/06 2020/05/06 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rigid:2/6i9UZxwEXjOQHa7xe1bpujt/U false his tag:n-n|tag:n-n his tag:n-n|tag:n-n 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:P0C6X7-PRO_0000037316 intact:EBI-25475825 intact:EBI-25475825 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0028"(cosedimentation in solution) Sutton et al. (2004) pubmed:14962394|imex:IM-27958 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25595353|imex:IM-27958-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) intact:EBI-7843867(chain-parent) - chain-seq-start:4118|chain-seq-end:4230 chain-seq-start:4118|chain-seq-end:4230 figure legend:Figure 4B|comment:For tagged protein; at high concentration and high speed, nsp9 behaves as a dimer with an approximate Kd of 0.46mM.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/06 2020/05/06 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rigid:2/6i9UZxwEXjOQHa7xe1bpujt/U false his tag:n-n|tag:n-n his tag:n-n|tag:n-n 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:P0C6X7-PRO_0000037316 intact:EBI-25487941 intact:EBI-25475825 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0028"(cosedimentation in solution) Sutton et al. (2004) pubmed:14962394|imex:IM-27958 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25595385|imex:IM-27958-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) intact:EBI-7843867(chain-parent) - chain-seq-start:3920|chain-seq-end:4117 chain-seq-start:4118|chain-seq-end:4230 figure legend:Figure 4C|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/06 2020/05/06 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rigid:YHKNXoSsk4WAvhYCE5Gl2Wgmabc false his tag:n-n|tag:n-n his tag:n-n|tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:P0C6X7-PRO_0000037316 intact:EBI-25475825 intact:EBI-25475825 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0028"(cosedimentation in solution) Sutton et al. (2004) pubmed:14962394|imex:IM-27958 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25595411|imex:IM-27958-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) intact:EBI-7843867(chain-parent) - chain-seq-start:4118|chain-seq-end:4230 chain-seq-start:4118|chain-seq-end:4230 figure legend:Figure 4B|comment:For untagged protein; nsp9 behaves as a dimer with an approximate Kd of 0.16mM which is not significantly different from the value obtained for the tagged protein.|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/06 2020/05/06 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rigid:2/6i9UZxwEXjOQHa7xe1bpujt/U false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-25595415 uniprotkb:P0C6X7-PRO_0000037316 - intact:EBI-25475825 psi-mi:unknown_ribonucleotide_oligo(display_short)|psi-mi:EBI-25595415(display_long) psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Sutton et al. (2004) pubmed:14962394|imex:IM-27958 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25595369|imex:IM-27958-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) ddbj/embl/genbank:NC_003714.1(see-also) intact:EBI-7843867(chain-parent) - - chain-seq-start:4118|chain-seq-end:4230 figure legend:Figure 4D|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/06 2020/05/06 - rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 - false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)