#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P13036 uniprotkb:P02929 intact:EBI-1131517|uniprotkb:Q2M624|ensemblbacteria:AAC77247|ensemblbacteria:BAE78282 intact:EBI-6399993|ensemblbacteria:AAC74334|ensemblbacteria:BAA14784|uniprotkb:P76831|uniprotkb:P94719|uniprotkb:P94722|uniprotkb:P94726|uniprotkb:P94728|uniprotkb:P94732|uniprotkb:P94736|uniprotkb:P94739|uniprotkb:P97239 psi-mi:feca_ecoli(display_long)|uniprotkb:fecA(gene name)|psi-mi:fecA(display_short)|uniprotkb:b4291(locus name)|uniprotkb:JW4251(locus name)|uniprotkb:"Iron(III) dicitrate transport protein FecA"(gene name synonym) psi-mi:tonb_ecoli(display_long)|uniprotkb:tonB(gene name)|psi-mi:tonB(display_short)|uniprotkb:exbA(gene name synonym)|uniprotkb:JW5195(locus name)|uniprotkb:b1252(locus name) psi-mi:"MI:0030"(cross-linking study) Ogierman et al. (2003) imex:IM-28005|pubmed:12618451 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25608408|dip:DIP-192943E|imex:IM-28005-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418711.1|refseq:WP_000188283.1|ensemblbacteria:AAC77247(transcript)|ensemblbacteria:b4291(gene)|ensemblbacteria:BAE78282(gene)|ensemblbacteria:BAE78282(transcript)|go:"GO:0006826"(iron ion transport)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015091"(ferric iron transmembrane transporter activity)|go:"GO:0015344"(siderophore uptake transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR011662(Secretin/TonB, short N-terminal)|interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR036942|interpro:IPR037066|rcsb pdb:1KMO|rcsb pdb:1KMP|rcsb pdb:1PO0|rcsb pdb:1PO3|rcsb pdb:1ZZV|rcsb pdb:2D1U|rcsb pdb:1PNZ|dip:DIP-9583N refseq:WP_001360141.1|ensemblbacteria:AAC74334(transcript)|ensemblbacteria:b1252(gene)|ensemblbacteria:BAA14784(gene)|ensemblbacteria:BAA14784(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015891"(siderophore transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042914"(colicin transport)|go:"GO:0071575"(integral component of external side of plasma membrane)|go:"GO:0098002"(receptor-mediated bacteriophage irreversible attachment to host cell)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003538(Gram-negative bacterial tonB protein)|interpro:IPR006260(TonB, C-terminal)|interpro:IPR037682|rcsb pdb:1IHR|rcsb pdb:1QXX|rcsb pdb:1U07|rcsb pdb:1XX3|rcsb pdb:2GRX|rcsb pdb:2GSK|refseq:NP_415768.1|dip:DIP-48111N psi-mi:"MI:0465"(dip) - - figure legend:Fig. 5A. 5B, 6, 8|comment:Interaction occurs in the absence of a functional TonB/ExbB/ExbD complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2020/05/12 2020/05/13 rogid:cUwH9Ef2cbWHQ8ioykPhpsauApY83333 rogid:ia5lbqqvP+O4DJyZcLSRdxZV/tE83333 rigid:jWyBFsreymDcgz+00ofSXJEmznE false mutation:113-113|mutation:115-115|mutation:114-114|mutation:116-116|mutation:117-117 mutation:160-160 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13036 uniprotkb:P02929 intact:EBI-1131517|uniprotkb:Q2M624|ensemblbacteria:AAC77247|ensemblbacteria:BAE78282 intact:EBI-6399993|ensemblbacteria:AAC74334|ensemblbacteria:BAA14784|uniprotkb:P76831|uniprotkb:P94719|uniprotkb:P94722|uniprotkb:P94726|uniprotkb:P94728|uniprotkb:P94732|uniprotkb:P94736|uniprotkb:P94739|uniprotkb:P97239 psi-mi:feca_ecoli(display_long)|uniprotkb:fecA(gene name)|psi-mi:fecA(display_short)|uniprotkb:b4291(locus name)|uniprotkb:JW4251(locus name)|uniprotkb:"Iron(III) dicitrate transport protein FecA"(gene name synonym) psi-mi:tonb_ecoli(display_long)|uniprotkb:tonB(gene name)|psi-mi:tonB(display_short)|uniprotkb:exbA(gene name synonym)|uniprotkb:JW5195(locus name)|uniprotkb:b1252(locus name) psi-mi:"MI:0030"(cross-linking study) Ogierman et al. (2003) imex:IM-28005|pubmed:12618451 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25609568|imex:IM-28005-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418711.1|refseq:WP_000188283.1|ensemblbacteria:AAC77247(transcript)|ensemblbacteria:b4291(gene)|ensemblbacteria:BAE78282(gene)|ensemblbacteria:BAE78282(transcript)|go:"GO:0006826"(iron ion transport)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015091"(ferric iron transmembrane transporter activity)|go:"GO:0015344"(siderophore uptake transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR011662(Secretin/TonB, short N-terminal)|interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR036942|interpro:IPR037066|rcsb pdb:1KMO|rcsb pdb:1KMP|rcsb pdb:1PO0|rcsb pdb:1PO3|rcsb pdb:1ZZV|rcsb pdb:2D1U|rcsb pdb:1PNZ|dip:DIP-9583N refseq:WP_001360141.1|ensemblbacteria:AAC74334(transcript)|ensemblbacteria:b1252(gene)|ensemblbacteria:BAA14784(gene)|ensemblbacteria:BAA14784(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015891"(siderophore transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042914"(colicin transport)|go:"GO:0071575"(integral component of external side of plasma membrane)|go:"GO:0098002"(receptor-mediated bacteriophage irreversible attachment to host cell)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003538(Gram-negative bacterial tonB protein)|interpro:IPR006260(TonB, C-terminal)|interpro:IPR037682|rcsb pdb:1IHR|rcsb pdb:1QXX|rcsb pdb:1U07|rcsb pdb:1XX3|rcsb pdb:2GRX|rcsb pdb:2GSK|refseq:NP_415768.1|dip:DIP-48111N psi-mi:"MI:0465"(dip) - - figure legend:Fig. 5A. 5B, 6, 8|comment:Interaction occurs in the absence of a functional TonB/ExbB/ExbD complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2020/05/12 2020/05/13 rogid:cUwH9Ef2cbWHQ8ioykPhpsauApY83333 rogid:ia5lbqqvP+O4DJyZcLSRdxZV/tE83333 rigid:jWyBFsreymDcgz+00ofSXJEmznE false mutation:113-113|mutation:115-115|mutation:114-114|mutation:116-116|mutation:117-117 mutation:162-162 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P13036 uniprotkb:P02929 intact:EBI-1131517|uniprotkb:Q2M624|ensemblbacteria:AAC77247|ensemblbacteria:BAE78282 intact:EBI-6399993|ensemblbacteria:AAC74334|ensemblbacteria:BAA14784|uniprotkb:P76831|uniprotkb:P94719|uniprotkb:P94722|uniprotkb:P94726|uniprotkb:P94728|uniprotkb:P94732|uniprotkb:P94736|uniprotkb:P94739|uniprotkb:P97239 psi-mi:feca_ecoli(display_long)|uniprotkb:fecA(gene name)|psi-mi:fecA(display_short)|uniprotkb:b4291(locus name)|uniprotkb:JW4251(locus name)|uniprotkb:"Iron(III) dicitrate transport protein FecA"(gene name synonym) psi-mi:tonb_ecoli(display_long)|uniprotkb:tonB(gene name)|psi-mi:tonB(display_short)|uniprotkb:exbA(gene name synonym)|uniprotkb:JW5195(locus name)|uniprotkb:b1252(locus name) psi-mi:"MI:0030"(cross-linking study) Ogierman et al. (2003) imex:IM-28005|pubmed:12618451 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25609598|imex:IM-28005-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418711.1|refseq:WP_000188283.1|ensemblbacteria:AAC77247(transcript)|ensemblbacteria:b4291(gene)|ensemblbacteria:BAE78282(gene)|ensemblbacteria:BAE78282(transcript)|go:"GO:0006826"(iron ion transport)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015091"(ferric iron transmembrane transporter activity)|go:"GO:0015344"(siderophore uptake transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR011662(Secretin/TonB, short N-terminal)|interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR036942|interpro:IPR037066|rcsb pdb:1KMO|rcsb pdb:1KMP|rcsb pdb:1PO0|rcsb pdb:1PO3|rcsb pdb:1ZZV|rcsb pdb:2D1U|rcsb pdb:1PNZ|dip:DIP-9583N refseq:WP_001360141.1|ensemblbacteria:AAC74334(transcript)|ensemblbacteria:b1252(gene)|ensemblbacteria:BAA14784(gene)|ensemblbacteria:BAA14784(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015891"(siderophore transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042914"(colicin transport)|go:"GO:0071575"(integral component of external side of plasma membrane)|go:"GO:0098002"(receptor-mediated bacteriophage irreversible attachment to host cell)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003538(Gram-negative bacterial tonB protein)|interpro:IPR006260(TonB, C-terminal)|interpro:IPR037682|rcsb pdb:1IHR|rcsb pdb:1QXX|rcsb pdb:1U07|rcsb pdb:1XX3|rcsb pdb:2GRX|rcsb pdb:2GSK|refseq:NP_415768.1|dip:DIP-48111N psi-mi:"MI:0465"(dip) - - figure legend:Fig. 5A. 5B, 6, 8|comment:Interaction occurs in the absence of a functional TonB/ExbB/ExbD complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2020/05/12 2020/05/13 rogid:cUwH9Ef2cbWHQ8ioykPhpsauApY83333 rogid:ia5lbqqvP+O4DJyZcLSRdxZV/tE83333 rigid:jWyBFsreymDcgz+00ofSXJEmznE false mutation:116-116|mutation:117-117|mutation:113-113|mutation:115-115|mutation:114-114 mutation:163-163 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)