#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q03322 uniprotkb:Q04338 intact:EBI-38705|uniprotkb:D6VT92|ensemblfungi:YDR468C intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C psi-mi:tlg1_yeast(display_long)|uniprotkb:Syntaxin TLG1(gene name synonym)|uniprotkb:TLG1(gene name)|psi-mi:TLG1(display_short)|uniprotkb:YDR468C(locus name)|uniprotkb:D8035.11(orf name) psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name) psi-mi:"MI:0096"(pull down) Paumet et al. (2001) pubmed:11739407|imex:IM-27981 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25419556|imex:IM-27981-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002876|refseq:NP_010756.3|mint:Q03322|dip:DIP-2058N|ensemblfungi:YDR468C(gene)|ensemblfungi:YDR468C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:2C5I|rcsb pdb:2C5J|rcsb pdb:2C5K|reactome:R-SCE-6811440 refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338 - crc64:B33251C18645EF74 crc64:E55B4DA3B40FAD67 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/29 2020/01/29 rogid:NRoBWW6XcrB9Z5iWz3Bwg4gL2/I559292 rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292 rigid:nDMX2ME06zWhuIjpoN382rdxTEM false his tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q04338 uniprotkb:Q08144 intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name) psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym) psi-mi:"MI:0096"(pull down) Paumet et al. (2001) pubmed:11739407|imex:IM-27981 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25419723|imex:IM-27981-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338 refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144 - crc64:E55B4DA3B40FAD67 crc64:CEBD6FE11278B1F0 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/29 2020/01/29 rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292 rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292 rigid:zL1im1PCPqkL0FD3Gvs9ykdmJlc false glutathione s tranferase tag:n-n his tag:n-n|sufficient binding region:36-335 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q04338 uniprotkb:Q03322 intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C intact:EBI-38705|uniprotkb:D6VT92|ensemblfungi:YDR468C psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name) psi-mi:tlg1_yeast(display_long)|uniprotkb:Syntaxin TLG1(gene name synonym)|uniprotkb:TLG1(gene name)|psi-mi:TLG1(display_short)|uniprotkb:YDR468C(locus name)|uniprotkb:D8035.11(orf name) psi-mi:"MI:0096"(pull down) Paumet et al. (2001) pubmed:11739407|imex:IM-27981 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25419723|imex:IM-27981-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338 sgd:S000002876|refseq:NP_010756.3|mint:Q03322|dip:DIP-2058N|ensemblfungi:YDR468C(gene)|ensemblfungi:YDR468C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:2C5I|rcsb pdb:2C5J|rcsb pdb:2C5K|reactome:R-SCE-6811440 - crc64:E55B4DA3B40FAD67 crc64:B33251C18645EF74 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/29 2020/01/29 rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292 rogid:NRoBWW6XcrB9Z5iWz3Bwg4gL2/I559292 rigid:zL1im1PCPqkL0FD3Gvs9ykdmJlc false glutathione s tranferase tag:n-n his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q04338 uniprotkb:P33328 intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C intact:EBI-17512|uniprotkb:D6W324|ensemblfungi:YOR327C psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name) psi-mi:snc2_yeast(display_long)|uniprotkb:SNC2(gene name)|psi-mi:SNC2(display_short)|uniprotkb:YOR327C(locus name) psi-mi:"MI:0096"(pull down) Paumet et al. (2001) pubmed:11739407|imex:IM-27981 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25419736|imex:IM-27981-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338 refseq:NP_014972.3|sgd:S000005854|ensemblfungi:YOR327C(gene)|ensemblfungi:YOR327C_mRNA(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|dip:DIP-4667N|mint:P33328 - crc64:E55B4DA3B40FAD67 crc64:815F027FAD8A599B figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/29 2020/01/29 rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292 rogid:q9N0ivbJw8/WCA1l24ymObTMu0s559292 rigid:dnjBT4RtfUS/FY2BfgEWFTMmiEk false glutathione s tranferase tag:n-n his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q04338 uniprotkb:Q08144 intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C intact:EBI-19302|uniprotkb:D6W248|uniprotkb:E9P933|ensemblfungi:YOL018C psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name) psi-mi:tlg2_yeast(display_long)|uniprotkb:YOL018C(locus name)|uniprotkb:TLG2(gene name)|psi-mi:TLG2(display_short)|uniprotkb:Syntaxin TLG2(gene name synonym) psi-mi:"MI:0096"(pull down) Paumet et al. (2001) pubmed:11739407|imex:IM-27981 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25419736|imex:IM-27981-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338 refseq:NP_014624.1|sgd:S000005378|ensemblfungi:YOL018C(gene)|ensemblfungi:YOL018C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0006675"(mannosyl-inositol phosphorylceramide metabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031303"(integral component of endosome membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028673|reactome:R-SCE-6811440|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009306"(protein secretion)|dip:DIP-4244N|mint:Q08144 - crc64:E55B4DA3B40FAD67 crc64:CEBD6FE11278B1F0 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/29 2020/01/29 rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292 rogid:M7Ezt/D1lvPf/T8TrjQwtKNhFhw559292 rigid:dnjBT4RtfUS/FY2BfgEWFTMmiEk false glutathione s tranferase tag:n-n his tag:n-n|sufficient binding region:36-335 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q04338 uniprotkb:Q03322 intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C intact:EBI-38705|uniprotkb:D6VT92|ensemblfungi:YDR468C psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name) psi-mi:tlg1_yeast(display_long)|uniprotkb:Syntaxin TLG1(gene name synonym)|uniprotkb:TLG1(gene name)|psi-mi:TLG1(display_short)|uniprotkb:YDR468C(locus name)|uniprotkb:D8035.11(orf name) psi-mi:"MI:0096"(pull down) Paumet et al. (2001) pubmed:11739407|imex:IM-27981 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25419736|imex:IM-27981-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338 sgd:S000002876|refseq:NP_010756.3|mint:Q03322|dip:DIP-2058N|ensemblfungi:YDR468C(gene)|ensemblfungi:YDR468C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:2C5I|rcsb pdb:2C5J|rcsb pdb:2C5K|reactome:R-SCE-6811440 - crc64:E55B4DA3B40FAD67 crc64:B33251C18645EF74 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/29 2020/01/29 rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292 rogid:NRoBWW6XcrB9Z5iWz3Bwg4gL2/I559292 rigid:dnjBT4RtfUS/FY2BfgEWFTMmiEk false glutathione s tranferase tag:n-n his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q04338 uniprotkb:P33328 intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C intact:EBI-17512|uniprotkb:D6W324|ensemblfungi:YOR327C psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name) psi-mi:snc2_yeast(display_long)|uniprotkb:SNC2(gene name)|psi-mi:SNC2(display_short)|uniprotkb:YOR327C(locus name) psi-mi:"MI:0096"(pull down) Paumet et al. (2001) pubmed:11739407|imex:IM-27981 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25419752|imex:IM-27981-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338 refseq:NP_014972.3|sgd:S000005854|ensemblfungi:YOR327C(gene)|ensemblfungi:YOR327C_mRNA(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|dip:DIP-4667N|mint:P33328 - crc64:E55B4DA3B40FAD67 crc64:815F027FAD8A599B figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/29 2020/01/29 rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292 rogid:q9N0ivbJw8/WCA1l24ymObTMu0s559292 rigid:tdUFabX6iNItdwAOBBbmkj/PPUA false glutathione s tranferase tag:n-n his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q04338 uniprotkb:Q03322 intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C intact:EBI-38705|uniprotkb:D6VT92|ensemblfungi:YDR468C psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name) psi-mi:tlg1_yeast(display_long)|uniprotkb:Syntaxin TLG1(gene name synonym)|uniprotkb:TLG1(gene name)|psi-mi:TLG1(display_short)|uniprotkb:YDR468C(locus name)|uniprotkb:D8035.11(orf name) psi-mi:"MI:0096"(pull down) Paumet et al. (2001) pubmed:11739407|imex:IM-27981 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25419752|imex:IM-27981-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338 sgd:S000002876|refseq:NP_010756.3|mint:Q03322|dip:DIP-2058N|ensemblfungi:YDR468C(gene)|ensemblfungi:YDR468C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|rcsb pdb:2C5I|rcsb pdb:2C5J|rcsb pdb:2C5K|reactome:R-SCE-6811440 - crc64:E55B4DA3B40FAD67 crc64:B33251C18645EF74 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/29 2020/01/29 rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292 rogid:NRoBWW6XcrB9Z5iWz3Bwg4gL2/I559292 rigid:tdUFabX6iNItdwAOBBbmkj/PPUA false glutathione s tranferase tag:n-n his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)