#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04268	uniprotkb:P04268	intact:EBI-8073544|uniprotkb:P02559|uniprotkb:P49436|uniprotkb:P08942|uniprotkb:P18441|uniprotkb:P49438|uniprotkb:Q540N4|uniprotkb:P18442|intact:UNK-6021497|uniprotkb:P49439	intact:EBI-8073544|uniprotkb:P02559|uniprotkb:P49436|uniprotkb:P08942|uniprotkb:P18441|uniprotkb:P49438|uniprotkb:Q540N4|uniprotkb:P18442|intact:UNK-6021497|uniprotkb:P49439	psi-mi:tpm1_chick(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)	psi-mi:tpm1_chick(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Brown et al. (2001)	imex:IM-28415|pubmed:11438684	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25691304|imex:IM-28415-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_015134260.1|refseq:XP_015134264.1|refseq:XP_015134271.1|interpro:IPR000533(Tropomyosin)|rcsb pdb:3U1A|refseq:NP_990732.1|rcsb pdb:3MUD|rcsb pdb:1IC2|rcsb pdb:3MTU|rcsb pdb:3U1C|reactome:R-GGA-445355|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060048"(cardiac muscle contraction)	refseq:XP_015134260.1|refseq:XP_015134264.1|refseq:XP_015134271.1|interpro:IPR000533(Tropomyosin)|rcsb pdb:3U1A|refseq:NP_990732.1|rcsb pdb:3MUD|rcsb pdb:1IC2|rcsb pdb:3MTU|rcsb pdb:3U1C|reactome:R-GGA-445355|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060048"(cardiac muscle contraction)	pdbe:1ic2	function:Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments|comment:mint	function:Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments|comment:mint	figure legend:Fig. 4e|3d-resolution:2|3d-r-factors:24.9/28.4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/06/29	2020/06/29	rogid:9L+Pdvpc4y/snwZQKGjKr9is2D09031	rogid:9L+Pdvpc4y/snwZQKGjKr9is2D09031	rigid:znrM7GYe0XEG4m4lCoLt4gWo+n0	false	sufficient binding region:1-80	sufficient binding region:1-80	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)