#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P38615	uniprotkb:P21190	intact:EBI-10642|uniprotkb:Q6Q5K4|ensemblfungi:YMR139W|uniprotkb:D6VZW2	intact:EBI-9199|ensemblfungi:YJR094C|uniprotkb:D6VWR2	psi-mi:rim11_yeast(display_long)|uniprotkb:RIM11(gene name)|psi-mi:RIM11(display_short)|uniprotkb:GSK3(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:YMR139W(locus name)|uniprotkb:YM9375.08(orf name)|uniprotkb:Regulator of IME2 protein 11(gene name synonym)	psi-mi:ime1_yeast(display_long)|uniprotkb:IME1(gene name)|psi-mi:IME1(display_short)|uniprotkb:J1916(orf name)|uniprotkb:YJR094C(locus name)	psi-mi:"MI:0018"(two hybrid)	Malathi et al. (1999)	pubmed:10545448|imex:IM-28003	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25608378|dip:DIP-2606E|imex:IM-28003-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013859.1|sgd:S000004747|ensemblfungi:YMR139W(gene)|ensemblfungi:YMR139W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-SCE-3371453|mint:P38615|dip:DIP-1566N	ensemblfungi:YJR094C(gene)|ensemblfungi:YJR094C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|sgd:S000003854|refseq:NP_012627.1|dip:DIP-1567N	psi-mi:"MI:0465"(dip)	crc64:59D92C9D42408E97	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/05/12	2020/05/13	rogid:HR/odTTwzM907syfBEfaJny7t5Q559292	rogid:SNKIGrZsqwUO9IW/kQdg0DVgdH8559292	rigid:9D5edWQK/XhTZoAyqz/SbzEvRd4	false	-	mutation disrupting interaction strength:347-347|sufficient binding region:1-340|mutation disrupting interaction strength:321-321|necessary binding region:295-340|mutation decreasing interaction strength:360-360,347-347|mutation decreasing interaction strength:321-321,360-360	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39001	uniprotkb:P21190	intact:EBI-20086|uniprotkb:D6VSI8|ensemblfungi:YDR207C	intact:EBI-9199|ensemblfungi:YJR094C|uniprotkb:D6VWR2	psi-mi:ume6_yeast(display_long)|uniprotkb:UME6(gene name)|psi-mi:UME6(display_short)|uniprotkb:CAR80(gene name synonym)|uniprotkb:CARGR1(gene name synonym)|uniprotkb:YDR207C(locus name)|uniprotkb:YD8142.04C(orf name)|uniprotkb:Unscheduled meiotic gene expression protein 6(gene name synonym)|uniprotkb:Negative transcriptional regulator of IME2(gene name synonym)|uniprotkb:Regulator of inducer of meiosis protein 16(gene name synonym)|uniprotkb:NIM2(gene name synonym)|uniprotkb:RIM16(gene name synonym)	psi-mi:ime1_yeast(display_long)|uniprotkb:IME1(gene name)|psi-mi:IME1(display_short)|uniprotkb:J1916(orf name)|uniprotkb:YJR094C(locus name)	psi-mi:"MI:0018"(two hybrid)	Malathi et al. (1999)	pubmed:10545448|imex:IM-28003	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25609727|imex:IM-28003-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010493.1|sgd:S000002615|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009847"(spore germination)|go:"GO:0010673"(positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:6XAW|mint:P39001|ensemblfungi:YDR207C(gene)|ensemblfungi:YDR207C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001081"(nitrogen catabolite repression of transcription from RNA polymerase II promoter)|dip:DIP-959N	ensemblfungi:YJR094C(gene)|ensemblfungi:YJR094C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|sgd:S000003854|refseq:NP_012627.1|dip:DIP-1567N	psi-mi:"MI:0465"(dip)	crc64:0DDA0A6B4A157182	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/05/12	2020/05/13	rogid:FYPIyvIh6lPIX4TSkGdpT47v/WM559292	rogid:SNKIGrZsqwUO9IW/kQdg0DVgdH8559292	rigid:DuyhsD8ctotAHhe9BuHFXQvxYdU	false	-	mutation disrupting interaction strength:342-343,352-353,356-356,358-360|necessary binding region:341-360|mutation disrupting interaction strength:347-347|sufficient binding region:1-67,183-360|mutation disrupting interaction strength:321-321|mutation decreasing interaction strength:352-352,356-356,360-360|mutation disrupting interaction strength:360-360,347-347|mutation decreasing interaction strength:321-321,360-360	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38615	uniprotkb:P21190	intact:EBI-10642|uniprotkb:Q6Q5K4|ensemblfungi:YMR139W|uniprotkb:D6VZW2	intact:EBI-9199|ensemblfungi:YJR094C|uniprotkb:D6VWR2	psi-mi:rim11_yeast(display_long)|uniprotkb:RIM11(gene name)|psi-mi:RIM11(display_short)|uniprotkb:GSK3(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:YMR139W(locus name)|uniprotkb:YM9375.08(orf name)|uniprotkb:Regulator of IME2 protein 11(gene name synonym)	psi-mi:ime1_yeast(display_long)|uniprotkb:IME1(gene name)|psi-mi:IME1(display_short)|uniprotkb:J1916(orf name)|uniprotkb:YJR094C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Malathi et al. (1999)	pubmed:10545448|imex:IM-28003	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25608385|dip:DIP-2606E|imex:IM-28003-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013859.1|sgd:S000004747|ensemblfungi:YMR139W(gene)|ensemblfungi:YMR139W_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-SCE-3371453|mint:P38615|dip:DIP-1566N	ensemblfungi:YJR094C(gene)|ensemblfungi:YJR094C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|sgd:S000003854|refseq:NP_012627.1|dip:DIP-1567N	psi-mi:"MI:0465"(dip)	crc64:59D92C9D42408E97	-	figure legend:Fig. 2, 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/05/12	2020/05/13	rogid:HR/odTTwzM907syfBEfaJny7t5Q559292	rogid:SNKIGrZsqwUO9IW/kQdg0DVgdH8559292	rigid:9D5edWQK/XhTZoAyqz/SbzEvRd4	false	ha tag:?-?	sufficient binding region:1-67,183-360|mutation with no effect:347-347,360-360|mutation with no effect:342-343,352-353,356-356,358-360|necessary binding region:341-360|mutation disrupting interaction strength:321-321|mutation with no effect:321-321,360-360|mutation disrupting interaction strength:347-347	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)