#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-22235520 uniprotkb:O43615 - intact:EBI-861737|uniprotkb:Q8N193|uniprotkb:A8K0R9|uniprotkb:D6W664|ensembl:ENSP00000270538 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tim44_human(display_long)|uniprotkb:TIMM44(gene name)|psi-mi:TIMM44(display_short)|uniprotkb:MIMT44(gene name synonym)|uniprotkb:TIM44(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_006342.2|ensembl:ENSG00000104980(gene)|ensembl:ENST00000270538(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0051087"(chaperone binding)|interpro:IPR007379(Mitochondrial import inner membrane translocase, subunit Tim44)|interpro:IPR017303(Import inner membrane translocase, TIM44 subunit, mitochondria)|interpro:IPR032710|interpro:IPR039544|mint:O43615|rcsb pdb:2CW9|reactome:R-HSA-1268020 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Hwln5XuF3a9IMwVhP63Ud+LM5M09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96CC6 - intact:EBI-3865223|uniprotkb:Q1W6H2|uniprotkb:Q4TT59|uniprotkb:Q96S34|uniprotkb:Q9H6E1|uniprotkb:Q04842|ensembl:ENSP00000262316 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rhdf1_human(display_long)|uniprotkb:IRHOM1(gene name synonym)|uniprotkb:Rhomboid family member 1(gene name synonym)|uniprotkb:RHBDF1(gene name)|psi-mi:RHBDF1(display_short)|uniprotkb:C16orf8(gene name synonym)|uniprotkb:Rhomboid 5 homolog 1(gene name synonym)|uniprotkb:p100hRho(gene name synonym)|uniprotkb:DIST1(gene name synonym)|uniprotkb:Epidermal growth factor receptor-related protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_071895.3|refseq:XP_005255551.1|ensembl:ENSG00000007384(gene)|ensembl:ENST00000262316(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008283"(cell population proliferation)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019838"(growth factor binding)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|interpro:IPR022241|interpro:IPR022764|interpro:IPR035952 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:LE4/RJCgut92iUvHPPwAdSs6O7M9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NR77 - intact:EBI-1392944|ensembl:ENSP00000321271 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pxmp2_human(display_long)|uniprotkb:PXMP2(gene name)|psi-mi:PXMP2(display_short)|uniprotkb:PMP22(gene name synonym)|uniprotkb:22 kDa peroxisomal membrane protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_061133.1|ensembl:ENSG00000176894(gene)|ensembl:ENST00000317479(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|interpro:IPR007248(Mpv17/PMP22)|reactome:R-HSA-389661|reactome:R-HSA-9603798 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:YujoZztq9Zk8jAMeODfHj8Op1gQ9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P00403 - intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:NyMmciQe53E935KEZahz8cGPjIM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9Y320 - intact:EBI-6447886|ensembl:ENSP00000278422|uniprotkb:B7Z4R4|uniprotkb:Q8NBP9|uniprotkb:Q5J7Q7|uniprotkb:Q561W0|uniprotkb:Q53G73|uniprotkb:Q9H3L1|intact:EBI-7128726|intact:MINT-6945923 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tmx2_human(display_long)|uniprotkb:Cell proliferation-inducing gene 26 protein(gene name synonym)|uniprotkb:TXNDC14(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 14(gene name synonym)|uniprotkb:CGI-31(orf name)|uniprotkb:My009(orf name)|uniprotkb:PIG26(orf name)|uniprotkb:PSEC0045(orf name)|uniprotkb:UNQ237/PRO270(orf name)|uniprotkb:TMX2(gene name)|psi-mi:TMX2(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000213593(gene)|ensembl:ENST00000278422(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007420"(brain development)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037463|interpro:IPR039101|mint:Q9Y320|rcsb pdb:2DJ0|refseq:NP_001137484.1|refseq:NP_057043.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:5YbR806GhogQ2yI3r9uo8i97MzY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96G21 - intact:EBI-8641721|ensembl:ENSP00000259239|intact:MINT-3052989|intact:MINT-8163231|uniprotkb:Q3ZTT3 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:imp4_human(display_long)|uniprotkb:BXDC4(gene name synonym)|uniprotkb:IMP4(gene name)|psi-mi:IMP4(display_short)|uniprotkb:Brix domain-containing protein 4(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000136718(gene)|ensembl:ENST00000259239(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030684"(preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR044281|mint:Q96G21|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_001307233.1|refseq:NP_001307234.1|refseq:NP_001307235.1|refseq:NP_001307236.1|refseq:NP_001307238.1|refseq:NP_001307239.1|refseq:NP_001307240.1|refseq:NP_219484.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." function:"Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing"|comment:mint figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:O220J7eEl0dgQmdVSttk/TMtY4Y9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NX36 - intact:EBI-7206847|uniprotkb:D3DSF2|intact:MINT-6782695|ensembl:ENSP00000320303|ensembl:ENSP00000371373|ensembl:ENSP00000385777|ensembl:ENSP00000461084|ensembl:ENSP00000461665|ensembl:ENSP00000461737|ensembl:ENSP00000479716|ensembl:ENSP00000483670 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:djc28_human(display_long)|uniprotkb:DNAJC28(gene name)|psi-mi:DNAJC28(display_short)|uniprotkb:C21orf55(gene name synonym)|uniprotkb:C21orf78(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001307675.1|refseq:NP_001035282.1|refseq:NP_060303.2|ensembl:ENSG00000177692(gene)|ensembl:ENSG00000262911(gene)|ensembl:ENST00000314399(transcript)|ensembl:ENST00000381947(transcript)|ensembl:ENST00000402202(transcript)|ensembl:ENST00000571432(transcript)|ensembl:ENST00000572540(transcript)|ensembl:ENST00000573306(transcript)|ensembl:ENST00000615701(transcript)|ensembl:ENST00000617313(transcript)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007030"(Golgi organization)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0048213"(Golgi vesicle prefusion complex stabilization)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018961|interpro:IPR036869 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." function:May have a role in protein folding or as a chaperone|comment:mint|comment:homomint figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:zt1+vves9QEGzK2+8laiKCj77uk9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P61009 - intact:EBI-6166040|ensembl:ENSP00000427463|uniprotkb:P12280|uniprotkb:Q9H0S7 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:spcs3_human(display_long)|uniprotkb:SPCS3(gene name)|psi-mi:SPCS3(display_short)|uniprotkb:Microsomal signal peptidase 22/23 kDa subunit(gene name synonym)|uniprotkb:SPC22(gene name synonym)|uniprotkb:UNQ1841/PRO3567(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000129128(gene)|ensembl:ENST00000503362(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR007653(Signal peptidase 22 kDa subunit)|mint:P61009|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_068747.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:IJjfzKRjeZefoy2znnC4XC6wgOU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P25686 - intact:EBI-6166532|ensembl:ENSP00000338019|uniprotkb:A8K9P6|uniprotkb:Q8IUK1|uniprotkb:Q8IUK2|uniprotkb:Q96F52|uniprotkb:Q53QD7 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:dnjb2_human(display_long)|uniprotkb:DNAJB2(gene name)|psi-mi:DNAJB2(display_short)|uniprotkb:HSJ1(gene name synonym)|uniprotkb:HSPF3(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 3(gene name synonym)|uniprotkb:Heat shock protein J1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000135924(gene)|ensembl:ENST00000336576(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016234"(inclusion body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070628"(proteasome binding)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0090086"(negative regulation of protein deubiquitination)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:1903644"(regulation of chaperone-mediated protein folding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR018253|interpro:IPR036869|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042026"(protein refolding)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0043130"(ubiquitin binding)|mint:P25686|rcsb pdb:2LGW|interpro:IPR043183|refseq:NP_001034639.1|refseq:NP_006727.2|dip:DIP-29051N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:BpmS2Mrk3FLzXLC0o3vIvSVPd3c9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q6UXV4 - intact:EBI-9641073|uniprotkb:Q3KNU7|uniprotkb:Q5H9D1|ensembl:ENSP00000362268 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:mic27_human(display_long)|uniprotkb:APOOL(gene name)|psi-mi:APOOL(display_short)|uniprotkb:CXorf33(gene name synonym)|uniprotkb:FAM121A(gene name synonym)|uniprotkb:Protein FAM121A(gene name synonym)|uniprotkb:UNQ8193/PRO23204(orf name)|uniprotkb:Apolipoprotein O-like(gene name synonym)|uniprotkb:MIC27(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_940852.3|dip:DIP-47309N|ensembl:ENSG00000155008(gene)|ensembl:ENST00000373173(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|go:"GO:0140275"(MIB complex)|interpro:IPR019166|interpro:IPR033182|mint:Q6UXV4|reactome:R-HSA-114608|reactome:R-HSA-8949613 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:ylhhtQDkjSpam535KFeGRCsybfE9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P04439 - intact:EBI-1042870|uniprotkb:O02963|uniprotkb:O78073|uniprotkb:P79563|uniprotkb:Q30208|uniprotkb:Q31623|uniprotkb:Q95377|uniprotkb:Q9BD15|uniprotkb:Q9BD19|uniprotkb:Q9MW42|uniprotkb:Q9TQK5|ensembl:ENSP00000366005|ensembl:ENSP00000379873|intact:EBI-1050524|intact:EBI-1049899|intact:EBI-2839447|intact:EBI-1044129|intact:EBI-8770309|intact:EBI-21249599|uniprotkb:B1PKZ3|uniprotkb:O02939|uniprotkb:O02954|uniprotkb:O02955|uniprotkb:O19509|uniprotkb:O19546|uniprotkb:O19598|uniprotkb:O19605|uniprotkb:O19606|uniprotkb:O19619|uniprotkb:O19647|uniprotkb:O19673|uniprotkb:O19687|uniprotkb:O19695|uniprotkb:O19756|uniprotkb:O19794|uniprotkb:O19795|uniprotkb:O43906|uniprotkb:O43907|uniprotkb:O46874|uniprotkb:O62921|uniprotkb:O62924|uniprotkb:O77937|uniprotkb:O77938|uniprotkb:O77964|uniprotkb:O78171|uniprotkb:O98009|uniprotkb:P30455|uniprotkb:P30456|uniprotkb:P30457|uniprotkb:P30458|uniprotkb:O98010|uniprotkb:O98011|uniprotkb:O98137|uniprotkb:P01891|uniprotkb:P01892|uniprotkb:P05534|uniprotkb:P06338|uniprotkb:P10313|uniprotkb:P10314|uniprotkb:P10315|uniprotkb:P10316|uniprotkb:P13746|uniprotkb:P16188|uniprotkb:P16189|uniprotkb:P16190|uniprotkb:P18462|uniprotkb:P30443|uniprotkb:P30444|uniprotkb:P30445|uniprotkb:P30446|uniprotkb:P30447|uniprotkb:P30448|uniprotkb:P30449|uniprotkb:P30450|uniprotkb:P30451|uniprotkb:P30514|uniprotkb:P79505|uniprotkb:P79562|uniprotkb:Q09160|uniprotkb:Q29680|uniprotkb:P30512|uniprotkb:Q29747|uniprotkb:Q29835|uniprotkb:Q29837|uniprotkb:Q29838|uniprotkb:Q29899|uniprotkb:Q29908|uniprotkb:Q29909|uniprotkb:Q29910|uniprotkb:Q5S3G1|uniprotkb:Q65A82|uniprotkb:Q8MHM1|uniprotkb:Q8MHN9|uniprotkb:Q95352|uniprotkb:Q95355|uniprotkb:P30452|uniprotkb:P30459|uniprotkb:Q95380|uniprotkb:Q95IZ5|uniprotkb:Q9BCN0|uniprotkb:Q9GJE6|uniprotkb:Q9GJE7|uniprotkb:Q9GJE8|uniprotkb:Q9MY89|uniprotkb:Q9MYA3|uniprotkb:Q9MYA5|uniprotkb:Q9MYC4|uniprotkb:Q9MYE6|uniprotkb:Q9MYE9|uniprotkb:Q9MYG4|uniprotkb:Q9MYG5|uniprotkb:Q9MYI5|uniprotkb:Q9TP25|uniprotkb:Q9TPQ3|uniprotkb:Q9TPR8|uniprotkb:Q9TPX8|uniprotkb:Q9TPX9|uniprotkb:Q9TPY0|uniprotkb:Q95362|uniprotkb:Q9TQ24|uniprotkb:Q9TQE8|uniprotkb:Q9TQE9|uniprotkb:Q9TQF1|uniprotkb:Q9TQF5|uniprotkb:Q9TQF8|uniprotkb:Q9TQF9|uniprotkb:Q9TQG0|uniprotkb:Q9TQG5|uniprotkb:Q9TQG7|uniprotkb:Q9TQH5|uniprotkb:Q9TQI3|uniprotkb:Q9TQM6|uniprotkb:Q9TQN5|uniprotkb:Q9TQP5|uniprotkb:Q9TQP6|uniprotkb:Q9TQP7|uniprotkb:Q9UIN1|uniprotkb:Q9UIN2|uniprotkb:Q9UIP7|uniprotkb:Q9UQU3|uniprotkb:Q9UQU6|uniprotkb:Q9UQU7|uniprotkb:P30453|uniprotkb:P30454|intact:EBI-1050350|intact:EBI-21505155 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hlaa_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENST00000376809(transcript)|ensembl:ENST00000396634(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002419"(T cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|ensembl:ENSG00000206503(gene)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016045"(detection of bacterium)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0036037"(CD8-positive, alpha-beta T cell activation)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0062061"(TAP complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2000568"(positive regulation of memory T cell activation)|go:"GO:2001187"(positive regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|go:"GO:0050830"(defense response to Gram-positive bacterium)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P04439|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:1P7Q|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:5HYJ|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MGT|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3TO2|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:4E5X|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L3E|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MNQ|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4GKN|rcsb pdb:4NO5|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4OV5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4GKS|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4I48|rcsb pdb:4WJ5|rcsb pdb:4I4W|rcsb pdb:4WU5|rcsb pdb:4JFD|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4K7F|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQK|rcsb pdb:5SWQ|rcsb pdb:5TEZ|rcsb pdb:5W1W|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKF|rcsb pdb:5WKH|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT9|rcsb pdb:6D78|rcsb pdb:6D7G|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:5NME|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0C|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSD|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:6EWA|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-8866654|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6RSY|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6ID4|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6MPP|rcsb pdb:6NCA|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6OPD|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6PTE|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:2GUO|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2XPG|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|refseq:NP_002107.3|refseq:NP_001229687.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:RNvdwEiEB2h1Qfvd4BEIKiGzw1s9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O60264 - intact:EBI-352588|ensembl:ENSP00000283131 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:smca5_human(display_long)|uniprotkb:SMARCA5(gene name)|psi-mi:SMARCA5(display_short)|uniprotkb:SNF2H(gene name synonym)|uniprotkb:WCRF135(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENST00000283131(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:O60264|rcsb pdb:6NE3|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5693565|reactome:R-HSA-606279|refseq:NP_003592.3|ensembl:ENSG00000153147(gene)|dip:DIP-33204N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:XlXL5MRhAFlqHhGroPdm01lYEk89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q15649 - intact:EBI-2563564|uniprotkb:K7EQP1|uniprotkb:Q8WVJ3|uniprotkb:A8K493|ensembl:ENSP00000481504|ensembl:ENSP00000484687 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:znhi3_human(display_long)|uniprotkb:TRIP3(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 3(gene name synonym)|uniprotkb:HNF-4a coactivator(gene name synonym)|uniprotkb:ZNHIT3(gene name)|psi-mi:ZNHIT3(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_004764.1|ensembl:ENSG00000273611(gene)|ensembl:ENSG00000278574(gene)|ensembl:ENST00000617429(transcript)|ensembl:ENST00000620508(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048254"(snoRNA localization)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR040197|rcsb pdb:2YQQ|rcsb pdb:5L85|refseq:NP_001268361.1|refseq:NP_001268362.1|refseq:NP_001268363.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:SxaEXdRQAbzgxjubm6FKF2oJnOw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9H707 - intact:EBI-2555731|uniprotkb:Q6P5A6|uniprotkb:B3KUE9|ensembl:ENSP00000375582 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:zn552_human(display_long)|uniprotkb:ZNF552(gene name)|psi-mi:ZNF552(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_079038.2|ensembl:ENSG00000178935(gene)|ensembl:ENST00000391701(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:iBtlQJUfshM3z2VjtOUrQBSMjy89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8N0Y2 - intact:EBI-6660528|ensembl:ENSP00000338860|uniprotkb:Q9NUU1|uniprotkb:Q8WU35|uniprotkb:Q8TEQ9 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:zn444_human(display_long)|uniprotkb:ZNF444(gene name)|psi-mi:ZNF444(display_short)|uniprotkb:EZF2(gene name synonym)|uniprotkb:Endothelial zinc finger protein 2(gene name synonym)|uniprotkb:ZSCAN17(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 17(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000167685(gene)|ensembl:ENST00000337080(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|refseq:XP_011525370.1|refseq:NP_001240721.1|refseq:NP_060807.2|refseq:XP_005259091.1|refseq:XP_005259092.1|refseq:XP_005259093.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:mtsW9JRIoWkvBjEsovYO7sKkcos9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UPR6 - intact:EBI-22234228|ensembl:ENSP00000262961|uniprotkb:B4DHD0 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:zfr2_human(display_long)|uniprotkb:ZFR2(gene name)|psi-mi:ZFR2(display_short)|uniprotkb:KIAA1086(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000105278(gene)|ensembl:ENST00000262961(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR006561(DZF)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043519|ensembl:ENSP00000262961|ensembl:ENST00000438164|ensembl:ENSP00000388974|ensembl:ENST00000439086|ensembl:ENSP00000388567|refseq:NP_001139112.1|refseq:NP_055989.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:zn3n1FKffGCv1IAhYf7/kDxP/1M9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96MU7 - intact:EBI-2849854|uniprotkb:Q4W5Q3|uniprotkb:Q7Z622|uniprotkb:Q8TF35|intact:EBI-28984617|ensembl:ENSP00000339245|ensembl:ENSP00000479213 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ytdc1_human(display_long)|uniprotkb:YTHDC1(gene name)|psi-mi:YTHDC1(display_short)|uniprotkb:KIAA1966(gene name synonym)|uniprotkb:YT521(gene name synonym)|uniprotkb:Splicing factor YT521(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001026902.1|refseq:NP_588611.2|ensembl:ENSP00000339245|ensembl:ENST00000355665|ensembl:ENSP00000347888|ensembl:ENST00000613637|ensembl:ENSP00000484604|ensembl:ENSP00000479213|refseq:NP_001317627.1|rcsb pdb:6T01|rcsb pdb:6T02|rcsb pdb:6T03|rcsb pdb:6T04|rcsb pdb:6T05|rcsb pdb:6SZY|rcsb pdb:6T06|rcsb pdb:6T07|rcsb pdb:6T08|rcsb pdb:6T09|rcsb pdb:6T0A|rcsb pdb:6T0C|rcsb pdb:6T0D|rcsb pdb:6T0O|rcsb pdb:6T0X|rcsb pdb:6T0Z|rcsb pdb:6T10|rcsb pdb:6T11|rcsb pdb:6T12|rcsb pdb:6WE8|rcsb pdb:6WE9|rcsb pdb:6WEA|rcsb pdb:6YKE|rcsb pdb:6YKI|rcsb pdb:6YKJ|rcsb pdb:6YKZ|rcsb pdb:6YL0|rcsb pdb:6YL8|rcsb pdb:6YL9|rcsb pdb:6YM2|rcsb pdb:6YM6|rcsb pdb:6YM7|rcsb pdb:6YM8|rcsb pdb:6YNI|rcsb pdb:6YNJ|rcsb pdb:6YNK|rcsb pdb:6YNL|rcsb pdb:6YNM|rcsb pdb:6YNN|rcsb pdb:6YNO|rcsb pdb:6YNP|rcsb pdb:6YOQ|rcsb pdb:6ZCM|rcsb pdb:6ZCN|rcsb pdb:6ZD9|ensembl:ENSG00000083896(gene)|ensembl:ENSG00000275272(gene)|ensembl:ENST00000344157(transcript)|ensembl:ENST00000615500(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048160"(primary follicle stage)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR007275(YT521-B-like protein)|rcsb pdb:2YUD|rcsb pdb:4R3H|rcsb pdb:4R3I|rcsb pdb:6RT4|rcsb pdb:6RT5|rcsb pdb:6RT6|rcsb pdb:6RT7|rcsb pdb:6SYZ|rcsb pdb:6SZ1|rcsb pdb:6SZ2|rcsb pdb:6SZ3|rcsb pdb:6SZL|rcsb pdb:6SZN|rcsb pdb:6SZR|rcsb pdb:6SZT|rcsb pdb:6SZX go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:vfZLRHOJvCdw6OIA9xeqeSgJZgE9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q5BJH7 - intact:EBI-11288011|uniprotkb:H7BXS8|uniprotkb:Q5JPC2|uniprotkb:Q8WY70|uniprotkb:Q96C02|uniprotkb:Q96IC4|ensembl:ENSP00000343435 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:yif1b_human(display_long)|uniprotkb:YIF1B(gene name)|psi-mi:YIF1B(display_short)|uniprotkb:YIP1-interacting factor homolog B(gene name synonym)|uniprotkb:PP4519(orf name)|uniprotkb:UNQ3073/PRO9905(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001034761.1|refseq:NP_001034762.1|refseq:NP_001138934.1|refseq:NP_001138935.1|refseq:XP_005259442.1|refseq:XP_016882938.1|ensembl:ENSG00000167645(gene)|ensembl:ENST00000339413(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR005578(Hrf1)|mint:Q5BJH7 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Vq4GGKQqOKq1sydz+NMnUNcriWQ9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q5T750 - intact:EBI-2563033|ensembl:ENSP00000357764|uniprotkb:O14634 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:xp32_human(display_long)|uniprotkb:XP32(gene name)|psi-mi:XP32(display_short)|uniprotkb:C1orf68(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001019850.1|ensembl:ENSG00000198854(gene)|ensembl:ENST00000368775(transcript)|go:"GO:0008544"(epidermis development)|interpro:IPR026078|mint:Q5T750 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:QHKngjyz/pqUrpu1XJ8NINDtmm49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UEU0 - intact:EBI-723716|ensembl:ENSP00000450731|uniprotkb:O43547|uniprotkb:Q96J28 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:vti1b_human(display_long)|uniprotkb:Vesicle transport v-SNARE protein Vti1-like 1(gene name synonym)|uniprotkb:Vti1-rp1(gene name synonym)|uniprotkb:VTI1B(gene name)|psi-mi:VTI1B(display_short)|uniprotkb:VTI1(gene name synonym)|uniprotkb:VTI1L(gene name synonym)|uniprotkb:VTI1L1(gene name synonym)|uniprotkb:VTI2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_006361.1|ensembl:ENSG00000100568(gene)|ensembl:ENST00000554659(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR038407|rcsb pdb:2V8S|reactome:R-HSA-114608|go:"GO:0016021"(integral component of membrane) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:jJgdeKpTRzoaVS5zj+cPGKj05OM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P02788 - intact:EBI-1058602|ensembl:ENSP00000231751|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|uniprotkb:A8K9U8 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001308050.1|ensembl:ENST00000231751(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006959"(humoral immune response)|go:"GO:0008201"(heparin binding)|ensembl:ENSG00000012223(gene)|refseq:NP_001186078.1|refseq:NP_002334.2|go:"GO:0009986"(cell surface)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0030141"(secretory granule)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1900229"(negative regulation of single-species biofilm formation in or on host organism)|go:"GO:0042581"(specific granule)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|go:"GO:2000308"("negative regulation of tumor necrosis factor (ligand) superfamily member 11 production")|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:2001205"(negative regulation of osteoclast development)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0048525"(negative regulation of viral process)|interpro:IPR016357(Transferrin)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051673"(membrane disruption in another organism)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1H45|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1U62|refseq:NP_001308051.1|dip:DIP-41354N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O14773 - intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NS69 - intact:EBI-1047508|intact:EBI-1180569|ensembl:ENSP00000216034 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tom22_human(display_long)|uniprotkb:TOMM22(gene name)|psi-mi:TOMM22(display_short)|uniprotkb:TOM22(gene name synonym)|uniprotkb:Translocase of outer membrane 22 kDa subunit homolog(gene name synonym)|uniprotkb:1C9-2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_064628.1|ensembl:ENSG00000100216(gene)|ensembl:ENST00000216034(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR005683(Mitochondrial import translocase, subunit Tom22)|mint:Q9NS69|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:DI3BGFSB04B1/mMHJsBpOsCxrYk9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P49755 - intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048199"(vesicle targeting, to, from or within Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensembl:ENSG00000170348(gene)|ensembl:ENST00000303575(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_006818.3 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9Y3B3 - intact:EBI-2561467|ensembl:ENSP00000405926|uniprotkb:Q96K51|uniprotkb:Q8WUU6|intact:EBI-10990361|uniprotkb:Q8NBU8 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tmed7_human(display_long)|uniprotkb:TMED7(gene name)|psi-mi:TMED7(display_short)|uniprotkb:CGI-109(orf name)|uniprotkb:p24 family protein gamma-3(gene name synonym)|uniprotkb:p27(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000134970(gene)|ensembl:ENST00000456936(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR009038(GOLD)|interpro:IPR015718(P24 related)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q9Y3B3|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001157941.1|refseq:NP_861974.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:A0B8TdJSOf63pd4GZ65i4VH/M8g9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O60343 - intact:EBI-522028|uniprotkb:A7E2X8|uniprotkb:B4DU25|uniprotkb:B4E235|uniprotkb:B6ETN8|uniprotkb:B6ETN9|uniprotkb:Q68D14|uniprotkb:Q5W0B9|ensembl:ENSP00000366863 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tbcd4_human(display_long)|uniprotkb:Akt substrate of 160 kDa(gene name synonym)|uniprotkb:TBC1D4(gene name)|psi-mi:TBC1D4(display_short)|uniprotkb:KIAA0603(gene name synonym)|uniprotkb:AS160(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_055647.2|ensembl:ENSG00000136111(gene)|ensembl:ENST00000377636(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031339"(negative regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|refseq:NP_001273587.1|refseq:NP_001273588.1|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021785|interpro:IPR035969|mint:O60343|rcsb pdb:3QYB|rcsb pdb:7NIX|reactome:R-HSA-1445148 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:AfptaRNss/0wnCrivoxs2PgxNOM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P51649 - intact:EBI-2684180|uniprotkb:Q546H9|uniprotkb:B2RD26|uniprotkb:G5E949|uniprotkb:Q8N3W6|ensembl:ENSP00000350191 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ssdh_human(display_long)|uniprotkb:SSADH(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 5 member A1(gene name synonym)|uniprotkb:"NAD(+)-dependent succinic semialdehyde dehydrogenase"(gene name synonym)|uniprotkb:ALDH5A1(gene name)|psi-mi:ALDH5A1(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001071.1|refseq:NP_733936.1|ensembl:ENSG00000112294(gene)|ensembl:ENST00000357578(transcript)|go:"GO:0004777"("succinate-semialdehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0009450"(gamma-aminobutyric acid catabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR010102(Succinic semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51649|rcsb pdb:2W8N|rcsb pdb:2W8O|rcsb pdb:2W8P|rcsb pdb:2W8Q|rcsb pdb:2W8R|reactome:R-HSA-916853 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:gCoItLXLp6W0Cr45kAu+XwADFAs9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UBC9 - intact:EBI-355179|uniprotkb:A5YKK8|uniprotkb:B2R4G8|uniprotkb:O75597|uniprotkb:Q4ZGI7|uniprotkb:Q5T525|uniprotkb:Q8NET7|uniprotkb:Q9UDG3|uniprotkb:D3DV32|ensembl:ENSP00000295367|ensembl:ENSP00000330391 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sprr3_human(display_long)|uniprotkb:SPRR3(gene name)|psi-mi:SPRR3(display_short)|uniprotkb:SPRC(gene name synonym)|uniprotkb:Cornifin beta(gene name synonym)|uniprotkb:Esophagin(gene name synonym)|uniprotkb:22 kDa pancornulin(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001091058.1|refseq:NP_005407.1|ensembl:ENST00000295367(transcript)|ensembl:ENST00000331860(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003302("Cornifin (SPRR)")|reactome:R-HSA-6809371|ensembl:ENSG00000163209(gene) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:GZ2WJ8NNau2HRIopItKnuR8fvYw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P22531 - intact:EBI-2556846|uniprotkb:Q5T9T4|uniprotkb:Q96RM2|ensembl:ENSP00000357739|ensembl:ENSP00000357740 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:spr2e_human(display_long)|uniprotkb:Small proline-rich protein II(gene name synonym)|uniprotkb:SPRR2E(gene name)|psi-mi:SPRR2E(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001019380.2|ensembl:ENSG00000203785(gene)|ensembl:ENST00000368750(transcript)|ensembl:ENST00000368751(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|interpro:IPR029142|mint:P22531|reactome:R-HSA-6809371 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Pwemojva9RHkLb7mVmctpxenpf49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96I25 - intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P02814 - intact:EBI-738612|uniprotkb:Q9UBN0|uniprotkb:Q9UCT0|uniprotkb:B7ZMG7|ensembl:ENSP00000302400|ensembl:ENSP00000423138 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:smr3b_human(display_long)|uniprotkb:SMR3B(gene name)|psi-mi:SMR3B(display_short)|uniprotkb:PBII(gene name synonym)|uniprotkb:PRL3(gene name synonym)|uniprotkb:Proline-rich protein 3(gene name synonym)|uniprotkb:Proline-rich peptide P-B(gene name synonym)|uniprotkb:PROL3(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_006676.1|ensembl:ENSG00000171201(gene)|ensembl:ENST00000304915(transcript)|ensembl:ENST00000504825(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026288|mint:P02814 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:WJ7Ag6lcBGK16pBo7LaEWJ1hydg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P62316 - intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P63208 - intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O95470 - intact:EBI-1046170|uniprotkb:Q7Z732|uniprotkb:Q9ULG8|uniprotkb:Q9UN89|uniprotkb:B2RBD4|ensembl:ENSP00000362298 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sgpl1_human(display_long)|uniprotkb:Sphingosine-1-phosphate aldolase(gene name synonym)|uniprotkb:SGPL1(gene name)|psi-mi:SGPL1(display_short)|uniprotkb:KIAA1252(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003892.2|refseq:XP_011538618.1|refseq:XP_011538619.1|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|ensembl:ENSG00000166224(gene)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENST00000373202(transcript)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|go:"GO:0001553"(luteinization)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:4Q6R|reactome:R-HSA-1660661|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|refseq:XP_005270320.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:hGut7nnomGA7QJhsV4lHBNm+kEE9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q15427 - intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O75533 - intact:EBI-876542|ensembl:ENSP00000335321|uniprotkb:E9PCH3 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sf3b1_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0034693"(U11/U12 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015016(Splicing factor 3B subunit 1)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|mint:O75533|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:2PEH|rcsb pdb:3LQV|rcsb pdb:4OZ1|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6N3E|refseq:NP_036565.2|dip:DIP-29411N|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-5250924|reactome:R-HSA-72163|reactome:R-HSA-72165 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q01105 - intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9BVL4 - intact:EBI-16811833|ensembl:ENSP00000370288|uniprotkb:Q2TAL2|uniprotkb:Q5JZ81|uniprotkb:Q8WUI0 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:selo_human(display_long)|uniprotkb:Selenoprotein O(gene name synonym)|uniprotkb:SELENOO(gene name)|psi-mi:SELENOO(display_short)|uniprotkb:SELO(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000073169(gene)|ensembl:ENST00000380903(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0018117"(protein adenylylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070733"(protein adenylyltransferase activity)|interpro:IPR003846(Protein of unknown function UPF0061)|refseq:NP_113642.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Rfwzqq4U1s+f8ugyECwJWlWKD1Y9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O43819 - intact:EBI-357012|uniprotkb:Q3T1B5|uniprotkb:Q9UK87|ensembl:ENSP00000252785|ensembl:ENSP00000379046|ensembl:ENSP00000444242|ensembl:ENSP00000444433 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sco2_human(display_long)|uniprotkb:SCO2(gene name)|psi-mi:SCO2(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001162580.1|refseq:NP_001162581.1|refseq:NP_001162582.1|refseq:NP_005129.2|dip:DIP-46088N|go:"GO:0003012"(muscle system process)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0014823"(response to activity)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|mint:O43819|rcsb pdb:2RLI|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|ensembl:ENSG00000284194(gene)|ensembl:ENST00000252785(transcript)|ensembl:ENST00000395693(transcript)|ensembl:ENST00000535425(transcript)|ensembl:ENST00000543927(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001701"(in utero embryonic development) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:RaD9DPaOnFKJvwNRUK9KQdptmqc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O15027 - intact:EBI-357515|intact:EBI-1384174|uniprotkb:A1YCA4|uniprotkb:Q5SXP0|uniprotkb:Q5SXP1|uniprotkb:Q8N347|uniprotkb:Q96HP1|uniprotkb:J3KNL6|uniprotkb:Q4G0D7|intact:EBI-28968206|ensembl:ENSP00000325827|intact:EBI-10967582|intact:EBI-21024388 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sc16a_human(display_long)|uniprotkb:KIAA0310(gene name synonym)|uniprotkb:SEC16(gene name synonym)|uniprotkb:SEC16L(gene name synonym)|uniprotkb:SEC16 homolog A(gene name synonym)|uniprotkb:SEC16A(gene name)|psi-mi:SEC16A(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:XP_011517562.1|refseq:XP_005266191.1|refseq:XP_011517548.1|refseq:XP_011517549.1|refseq:XP_011517550.1|refseq:XP_011517557.1|refseq:XP_011517559.1|refseq:XP_011517561.1|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|mint:O15027|reactome:R-HSA-204005|ensembl:ENSG00000148396(gene)|ensembl:ENST00000313050(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031090"(organelle membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensembl:ENSP00000325827|refseq:NP_055681.1|refseq:XP_011517554.1|refseq:NP_001263347.1|dip:DIP-27588N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:yB65QJbL+WBjtWO5UXAx2DCRbwI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q6UWP8 - intact:EBI-11024569|uniprotkb:E9PBV3|uniprotkb:A8K5J0|ensembl:ENSP00000430242 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sbsn_human(display_long)|uniprotkb:SBSN(gene name)|psi-mi:SBSN(display_short)|uniprotkb:UNQ698/PRO1343(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001159506.1|refseq:NP_001159507.1|refseq:NP_940940.1|ensembl:ENSG00000189001(gene)|ensembl:ENST00000452271(transcript)|go:"GO:0070062"(extracellular exosome) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:odagYPEdS9Vav1RDWyUv1l+lQA49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P82663 - intact:EBI-1046734|uniprotkb:Q9H7P5|ensembl:ENSP00000253686|uniprotkb:B4DFJ5|uniprotkb:B4DQG6 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rt25_human(display_long)|uniprotkb:MRPS25(gene name)|psi-mi:MRPS25(display_short)|uniprotkb:RPMS25(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS25(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_071942.1|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000131368(gene)|ensembl:ENST00000253686(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005840"(ribosome)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR036249|interpro:IPR040049|mint:P82663|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:DQMtBaQJW2Ic025zsKJYfN4aj1I9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96EL2 - intact:EBI-1055789|uniprotkb:P82668|uniprotkb:Q96Q23|uniprotkb:Q9P047|uniprotkb:A4D1U9|ensembl:ENSP00000318158 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rt24_human(display_long)|uniprotkb:bMRP-47(gene name synonym)|uniprotkb:MRPS24(gene name)|psi-mi:MRPS24(display_short)|uniprotkb:HSPC335(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS3m(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_114403.1|ensembl:ENSG00000062582(gene)|ensembl:ENST00000317534(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR026146|mint:Q96EL2|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:OEtFmhoLM1Sw9YVrL88HZQ5Ju0g9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9BRJ2 - intact:EBI-2514313|ensembl:ENSP00000483030|uniprotkb:Q6ZMJ5|uniprotkb:A1L436 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rm45_human(display_long)|uniprotkb:MRPL45(gene name)|psi-mi:MRPL45(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL45(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000277936(gene)|ensembl:ENST00000621878(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR007379(Mitochondrial import inner membrane translocase, subunit Tim44)|interpro:IPR032710|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|dip:DIP-53786N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:9NtO1r7W7U9BW3vB9RTRbwehBZ49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NWU5 - intact:EBI-5461867|uniprotkb:Q5H9Q1|uniprotkb:Q96Q51|uniprotkb:Q9P006|intact:EBI-6137918|uniprotkb:A6NGJ8|ensembl:ENSP00000431040 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rm22_human(display_long)|uniprotkb:MRPL22(gene name)|psi-mi:MRPL22(display_short)|uniprotkb:MRPL25(gene name synonym)|uniprotkb:RPML25(gene name synonym)|uniprotkb:39S ribosomal protein L25, mitochondrial(gene name synonym)|uniprotkb:HSPC158(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein uL22m(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001014990.1|refseq:NP_054899.2|ensembl:ENSG00000082515(gene)|ensembl:ENST00000523037(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0042255"(ribosome assembly)|rcsb pdb:6ZM6|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7ODR|rcsb pdb:7ODS|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005727(Ribosomal protein L22, bacterial-type)|interpro:IPR036394|mint:Q9NWU5|rcsb pdb:3J7Y|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Nmwjb2QTu0IyJMS0SufI3PsBwmM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NX20 - intact:EBI-2560190|uniprotkb:Q9HB70|uniprotkb:Q9BYD0|ensembl:ENSP00000300151 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rm16_human(display_long)|uniprotkb:MRPL16(gene name)|psi-mi:MRPL16(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL16m(gene name synonym)|uniprotkb:PNAS-111(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_060310.1|ensembl:ENSG00000166902(gene)|ensembl:ENST00000300151(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000114(Ribosomal protein L16)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR036920|mint:Q9NX20|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:5ngQm8RUtN0SGgxJN2mGtWKhHMU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P62891 - intact:EBI-8830744|uniprotkb:P02404|uniprotkb:Q9BYF2|uniprotkb:P39025|ensembl:ENSP00000355315 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rl39_human(display_long)|uniprotkb:RPL39(gene name)|psi-mi:RPL39(display_short)|uniprotkb:Large ribosomal subunit protein eL39(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000991.1|rcsb pdb:4V6X|ensembl:ENSG00000198918(gene)|ensembl:ENST00000361575(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR020083|interpro:IPR023626|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:AZus2dxwJsTxAOwnJ93E2yhasbo9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q14257 - intact:EBI-356710|uniprotkb:A8MTG6|uniprotkb:Q53XN8|ensembl:ENSP00000378349|uniprotkb:F8WCY5 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rcn2_human(display_long)|uniprotkb:RCN2(gene name)|psi-mi:RCN2(display_short)|uniprotkb:ERC55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:E6-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002893.1|ensembl:ENST00000394885(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|ensembl:ENSG00000117906(gene)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q14257|refseq:NP_001258766.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:99ru/7eYUvZ5xdb+x4inbib3PP89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9Y2P8 - intact:EBI-11026509|uniprotkb:Q9NY00|uniprotkb:Q5VYW9|uniprotkb:Q9P044|uniprotkb:Q9H9D0|uniprotkb:D3DRI2|uniprotkb:Q5VZU1|ensembl:ENSP00000371169 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rcl1_human(display_long)|uniprotkb:RCL1(gene name)|psi-mi:RCL1(display_short)|uniprotkb:RNAC(gene name synonym)|uniprotkb:RPC2(gene name synonym)|uniprotkb:RPCL1(gene name synonym)|uniprotkb:RTC2(gene name synonym)|uniprotkb:HSPC338(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001273628.1|refseq:NP_001273629.1|refseq:NP_001273630.1|refseq:NP_005763.3|refseq:XP_011515975.1|ensembl:ENSG00000120158(gene)|ensembl:ENST00000381750(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|interpro:IPR000228(RNA 3'-terminal phosphate cyclase)|interpro:IPR013791(RNA 3'-terminal phosphate cyclase, subset, insert region)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR016443(RNA 3'-terminal phosphate cyclase-like, eukaryotic)|interpro:IPR020719|interpro:IPR023797|interpro:IPR036553|interpro:IPR037136|mint:Q9Y2P8|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:XP_016869665.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:8WnLDVPrx4t1eD6h+emL5waEyDY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q6XE24 - intact:EBI-20798786|uniprotkb:A8K9S4|uniprotkb:B7ZL17|uniprotkb:G5E9J9|uniprotkb:O75876|uniprotkb:Q17RI0|uniprotkb:Q6XE23|ensembl:ENSP00000373277 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rbms3_human(display_long)|uniprotkb:RBMS3(gene name)|psi-mi:RBMS3(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001003792.1|refseq:NP_001003793.1|refseq:NP_001171182.1|refseq:NP_001171183.1|refseq:NP_055298.2|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034406|interpro:IPR035979|ensembl:ENST00000383767(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|ensembl:ENSG00000144642(gene) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:ov3OkqXDD2ABwaRxQSA4cVFmCIU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O75127 - intact:EBI-2560233|uniprotkb:Q66K60|uniprotkb:Q9UDV2|uniprotkb:Q3ZB78|intact:EBI-28971087|ensembl:ENSP00000292478 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ptcd1_human(display_long)|uniprotkb:PTCD1(gene name)|psi-mi:PTCD1(display_short)|uniprotkb:KIAA0632(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_056360.2|ensembl:ENSP00000292478|ensembl:ENSG00000106246(gene)|ensembl:ENST00000292478(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0042780"(tRNA 3'-end processing)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|dip:DIP-56845N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:NkS3D5M+poxihNXmc5GnqkSSYnk9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O14818 - intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O75569 - intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:tZfziopZlC+1d3De97G3kDY+Tog9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q5JSZ5 - intact:EBI-744891|uniprotkb:Q66VZ2|uniprotkb:Q9H683|uniprotkb:Q5JSZ7|uniprotkb:O60270|intact:EBI-2512629|intact:EBI-947989|uniprotkb:Q68CR0|intact:EBI-2559356|uniprotkb:Q96EI9|ensembl:ENSP00000508005|ensembl:ENSP00000508048 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:prc2b_human(display_long)|uniprotkb:PRRC2B(gene name)|psi-mi:PRRC2B(display_short)|uniprotkb:HLA-B-associated transcript 2-like 1(gene name synonym)|uniprotkb:KIAA0515(gene name synonym)|uniprotkb:BAT2L(gene name synonym)|uniprotkb:BAT2L1(gene name synonym)|uniprotkb:Proline-rich coiled-coil protein 2B(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_037450.2|ensembl:ENST00000682501|ensembl:ENSP00000508073|ensembl:ENSP00000508048|ensembl:ENSP00000508005|ensembl:ENSG00000288701(gene)|ensembl:ENST00000683519(transcript)|ensembl:ENST00000684596(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0030154"(cell differentiation)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:Q5JSZ5 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:N1MgJl3k+WJTF+XUf5VFIB06B909606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q15166 - intact:EBI-6677114|ensembl:ENSP00000265627|uniprotkb:A4D1H8|uniprotkb:O75855|uniprotkb:O76060|uniprotkb:Q6IRU9|uniprotkb:Q8IX97|uniprotkb:Q9BZH9 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pon3_human(display_long)|uniprotkb:PON3(gene name)|psi-mi:PON3(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000105852(gene)|ensembl:ENST00000265627(transcript)|go:"GO:0004063"(aryldialkylphosphatase activity)|go:"GO:0004064"(arylesterase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0010124"(phenylacetate catabolic process)|go:"GO:0018733"(3,4-dihydrocoumarin hydrolase activity)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046226"(coumarin catabolic process)|go:"GO:0046395"(carboxylic acid catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102007"(acyl-L-homoserine-lactone lactonohydrolase activity)|go:"GO:0009636"(response to toxic substance)|interpro:IPR002640(Arylesterase)|interpro:IPR008364(Paraoxonase2)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|reactome:R-HSA-2142688|refseq:NP_000931.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:KzyA/Zs/1Tn8fmsUChooqHJNM3M9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P29590 - intact:EBI-295890|ensembl:ENSP00000268058|uniprotkb:P29591|uniprotkb:P29592|uniprotkb:P29593|uniprotkb:Q00755|uniprotkb:Q96S41|intact:EBI-779712|intact:EBI-1210702|intact:EBI-870812|uniprotkb:Q15959|uniprotkb:Q59FP9|uniprotkb:Q8WUA0|uniprotkb:Q9BPW2|uniprotkb:Q9BWP7|uniprotkb:Q9BZX6|uniprotkb:Q9BZX7|uniprotkb:Q9BZX8|uniprotkb:Q9BZX9|uniprotkb:Q9BZY0|uniprotkb:Q9BZY2|uniprotkb:Q9BZY3|uniprotkb:E9PBR7 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pml_human(display_long)|uniprotkb:PML(gene name)|psi-mi:PML(display_short)|uniprotkb:MYL(gene name synonym)|uniprotkb:RNF71(gene name synonym)|uniprotkb:TRIM19(gene name synonym)|uniprotkb:Tripartite motif-containing protein 19(gene name synonym)|uniprotkb:RING finger protein 71(gene name synonym)|uniprotkb:Promyelocytic leukemia protein(gene name synonym)|uniprotkb:PP8675(gene name synonym)|uniprotkb:E3 SUMO-protein ligase PML(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase PML(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENST00000268058(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000140464(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010522"(regulation of calcium ion transport into cytosol)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030578"(PML body organization)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032183"(SUMO binding)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0034097"(response to cytokine)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0032938"(negative regulation of translation in response to oxidative stress)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046332"(SMAD binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090398"(cellular senescence)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:1902187"|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|rcsb pdb:2MWX|rcsb pdb:4WJN|rcsb pdb:4WJO|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|rcsb pdb:5YUF|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:6IMQ|rcsb pdb:6UYO|rcsb pdb:6UYP|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:6UYT|rcsb pdb:6UYU|rcsb pdb:6UYV|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-6804758|reactome:R-HSA-877300|reactome:R-HSA-8934593|reactome:R-HSA-8948747|reactome:R-HSA-9609690|reactome:R-HSA-9616222|interpro:IPR021978|mint:P29590|rcsb pdb:1BOR|rcsb pdb:2MVW|refseq:NP_002666.1|refseq:NP_150241.2|refseq:NP_150242.1|refseq:NP_150243.2|refseq:NP_150247.2|refseq:NP_150249.1|refseq:NP_150250.2|refseq:NP_150252.1|refseq:NP_150253.2|dip:DIP-33053N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:FdAh5Rbyu37luTScMzCopbbwXvk9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P13796 - intact:EBI-698036|uniprotkb:Q5TBN4|uniprotkb:B2R613|uniprotkb:B4DUA0|ensembl:ENSP00000315757|ensembl:ENSP00000381581 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:plsl_human(display_long)|uniprotkb:L-plastin(gene name synonym)|uniprotkb:Lymphocyte cytosolic protein 1(gene name synonym)|uniprotkb:LC64P(gene name synonym)|uniprotkb:LCP1(gene name)|psi-mi:LCP1(display_short)|uniprotkb:PLS2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002289.2|refseq:XP_005266431.1|dip:DIP-34767N|ensembl:ENSG00000136167(gene)|ensembl:ENST00000323076(transcript)|ensembl:ENST00000398576(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002102"(podosome)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051639"(actin filament network formation)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|rcsb pdb:2D85|rcsb pdb:5JOJ|rcsb pdb:5JOL|reactome:R-HSA-8950505 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:1uy1zhroB3GHUiAwLjEdP5Rz1xM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P41247 - intact:EBI-21888229|uniprotkb:A8K1H3|uniprotkb:B4E362|uniprotkb:Q8WW83|ensembl:ENSP00000370430|ensembl:ENSP00000415245 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:plpl4_human(display_long)|uniprotkb:Protein GS2(gene name synonym)|uniprotkb:PNPLA4(gene name)|psi-mi:PNPLA4(display_short)|uniprotkb:DXS1283E(gene name synonym)|uniprotkb:GS2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001135861.1|refseq:NP_001166143.1|refseq:NP_004641.1|refseq:XP_011543890.1|ensembl:ENSG00000006757(gene)|ensembl:ENST00000381042(transcript)|ensembl:ENST00000444736(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0047376"(all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity)|go:"GO:0050253"(retinyl-palmitate esterase activity)|go:"GO:0055088"(lipid homeostasis)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR033562|interpro:IPR033902|reactome:R-HSA-163560 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:mKX9V+kd+f4dUWiDf4Rl2PiOF/g9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8IXK0 - intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P09874 - intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8TEW0 - intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q13310 - intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P11940 - intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q14980 - intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P80303 - intact:EBI-2296670|uniprotkb:D3DQX5|uniprotkb:A8K642|uniprotkb:Q8NFT5|uniprotkb:V9HW75|ensembl:ENSP00000436455|ensembl:ENSP00000481959 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:nucb2_human(display_long)|uniprotkb:NUCB2(gene name)|psi-mi:NUCB2(display_short)|uniprotkb:NEFA(gene name synonym)|uniprotkb:DNA-binding protein NEFA(gene name synonym)|uniprotkb:Gastric cancer antigen Zg4(gene name synonym)|uniprotkb:Prepronesfatin(gene name synonym)|uniprotkb:Epididymis secretory protein Li 109(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_005004.1|refseq:XP_016873295.1|refseq:XP_016873296.1|refseq:XP_016873297.1|refseq:XP_016873298.1|refseq:XP_016873299.1|refseq:XP_016873300.1|refseq:XP_016873301.1|refseq:XP_016873302.1|refseq:XP_016873303.1|refseq:XP_016873304.1|refseq:XP_016873305.1|refseq:XP_016873306.1|refseq:XP_016873307.1|refseq:XP_016873308.1|ensembl:ENSG00000070081(gene)|ensembl:ENST00000529010(transcript)|ensembl:ENST00000622082(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028813|go:"GO:0005886"(plasma membrane)|interpro:IPR040250|mint:P80303 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:m5wJa0MtTVxrydwG9BXzjUMAlyc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96CB9 - intact:EBI-744435|uniprotkb:Q5TDF7|uniprotkb:Q96AN8|uniprotkb:Q9HAJ8|uniprotkb:A8K6S6|uniprotkb:B3KQ50|uniprotkb:B4DHA4|ensembl:ENSP00000419740 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:nsun4_human(display_long)|uniprotkb:NOL1/NOP2/Sun domain family member 4(gene name synonym)|uniprotkb:NSUN4(gene name)|psi-mi:NSUN4(display_short)|uniprotkb:5-methylcytosine tRNA methyltransferase NSUN4(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_950245.2|refseq:NP_001243056.1|refseq:NP_001243057.1|ensembl:ENSG00000117481(gene)|ensembl:ENST00000474844(transcript)|go:"GO:0001510"(RNA methylation)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009383"("rRNA (cytosine-C5-)-methyltransferase activity")|go:"GO:0019843"(rRNA binding)|go:"GO:0031167"(rRNA methylation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR029063|rcsb pdb:4FP9|rcsb pdb:4FZV|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF7|reactome:R-HSA-6793080|dip:DIP-58104N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:THTOojjCrz9JfKXrUr2yVIYyUB49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NX24 - intact:EBI-1050064|uniprotkb:Q9P095|uniprotkb:A6NKY8|intact:EBI-5774108|ensembl:ENSP00000274606 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:nhp2_human(display_long)|uniprotkb:Nucleolar protein family A member 2(gene name synonym)|uniprotkb:snoRNP protein NHP2(gene name synonym)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:NOLA2(gene name synonym)|uniprotkb:HSPC286(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_060308.1|refseq:NP_001030005.1|ensembl:ENSG00000145912(gene)|ensembl:ENST00000274606(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:Q9NX24|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:ZZchZSzrw15BqMfddUMcaxZRF0w9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UHQ9 - intact:EBI-953870|ensembl:ENSP00000356218|uniprotkb:A0PK21|uniprotkb:O95329|uniprotkb:Q53F73|uniprotkb:Q8NCL5|uniprotkb:Q9UHJ1|uniprotkb:B2R8E0 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:nb5r1_human(display_long)|uniprotkb:"NAD(P)H:quinone oxidoreductase type 3 polypeptide A2"(gene name synonym)|uniprotkb:Humb5R2(gene name synonym)|uniprotkb:CYB5R1(gene name)|psi-mi:CYB5R1(display_short)|uniprotkb:NQO3A2(gene name synonym)|uniprotkb:UNQ3049/PRO9865(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000159348(gene)|ensembl:ENST00000367249(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071949"(FAD binding)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|reactome:R-HSA-114608|reactome:R-HSA-1237044|go:"GO:0016020"(membrane)|refseq:NP_057327.2 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:TOvJYSyfYu73Ac/SYjup+ABu74g9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P43490 - intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553|ensembl:ENSP00000390591|ensembl:ENSP00000506129|ensembl:ENSP00000506540 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_005737.1|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|reactome:R-HSA-1368108|reactome:R-HSA-197264|rcsb pdb:6B76|ensembl:ENSG00000105835(gene)|ensembl:ENST00000222553(transcript)|ensembl:ENST00000424768(transcript)|ensembl:ENST00000681255(transcript)|ensembl:ENST00000681491(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005125"(cytokine activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047280"(nicotinamide phosphoribosyltransferase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070997"(neuron death)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905377"(response to D-galactose)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|refseq:XP_005250157.1|dip:DIP-29218N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NQX4 - intact:EBI-1237297|uniprotkb:Q6P1W8|ensembl:ENSP00000261839 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:myo5c_human(display_long)|uniprotkb:MYO5C(gene name)|psi-mi:MYO5C(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_061198.2|ensembl:ENST00000261839(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|ensembl:ENSG00000128833(gene)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|interpro:IPR037991|rcsb pdb:4L8T|rcsb pdb:4ZG4|rcsb pdb:5HMP|go:"GO:0030050"(vesicle transport along actin filament) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:p3wlaboghTdnrQ1yGUpURcRHf/A9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UDX5 - intact:EBI-1042890|uniprotkb:Q9H3K1|uniprotkb:Q9P0N6|uniprotkb:A6NFQ5|ensembl:ENSP00000266263 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:mtfp1_human(display_long)|uniprotkb:MTFP1(gene name)|psi-mi:MTFP1(display_short)|uniprotkb:HSPC242(orf name)|uniprotkb:My022(orf name)|uniprotkb:Mitochondrial 18 kDa protein(gene name synonym)|uniprotkb:MTP18(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000242114(gene)|ensembl:ENST00000266263(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019560|refseq:NP_001003704.1|refseq:NP_057582.2 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:ALtZgmbrJPk5pO2HT0pegGWmTLc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q13724 - intact:EBI-720141|uniprotkb:Q17RN9|uniprotkb:Q8TCT5|uniprotkb:A8K938|ensembl:ENSP00000410992|uniprotkb:F5H6D0 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:mogs_human(display_long)|uniprotkb:Processing A-glucosidase I(gene name synonym)|uniprotkb:MOGS(gene name)|psi-mi:MOGS(display_short)|uniprotkb:GCS1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001139630.1|refseq:NP_006293.2|ensembl:ENSG00000115275(gene)|ensembl:ENST00000448666(transcript)|go:"GO:0004573"(Glc3Man9GlcNAc2 oligosaccharide glucosidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0015926"(glucosidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004888(Glycoside hydrolase, family 63)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR031335|interpro:IPR031631|interpro:IPR038518|mint:Q13724|reactome:R-HSA-4793954|reactome:R-HSA-532668|reactome:R-HSA-9683686|reactome:R-HSA-9694548 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:odbL3NUcP483ilKg/CMVn2GtdVs9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9BU76 - intact:EBI-742459|uniprotkb:Q6P5Y0|uniprotkb:Q6ZTZ6|uniprotkb:Q6ZWA6|uniprotkb:Q8IZH3|ensembl:ENSP00000272139 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:mmta2_human(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_077295.1|mint:Q9BU76|reactome:R-HSA-6798695|ensembl:ENSG00000143793(gene)|ensembl:ENST00000272139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0034774"(secretory granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019315|interpro:IPR039207 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:TwnLhBYwwR6yPCw3sd7g/sPHJd09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9BQA1 - intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:0q4wunYtHalObC8r1wphhelIpr49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q7KZI7 - intact:EBI-516560|uniprotkb:Q15449|uniprotkb:Q15524|uniprotkb:Q5XGA3|uniprotkb:Q68A18|uniprotkb:Q96HB3|uniprotkb:Q96RG0|ensembl:ENSP00000385751 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:mark2_human(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001034558.2|refseq:NP_001156768.1|refseq:NP_001156769.1|refseq:NP_004945.4|refseq:NP_059672.2|dip:DIP-31321N|ensembl:ENSG00000072518(gene)|ensembl:ENST00000402010(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001764"(neuron migration)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008289"(lipid binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0061564"(axon development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097427"(microtubule bundle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904526"(regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|mint:Q7KZI7|rcsb pdb:3IEC|rcsb pdb:5EAK|rcsb pdb:5KZ7|rcsb pdb:5KZ8 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:yfUqSCu4bgkncBd6hRRg5pKkArc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O95819 - intact:EBI-2511133|intact:EBI-28985706|ensembl:ENSP00000314363|uniprotkb:Q9NST7|uniprotkb:O75172|uniprotkb:E7ESS2 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:m4k4_human(display_long)|uniprotkb:MAP4K4(gene name)|psi-mi:MAP4K4(display_short)|uniprotkb:HGK(gene name synonym)|uniprotkb:KIAA0687(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_663719.2|ensembl:ENST00000347699(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032014"(positive regulation of ARF protein signal transduction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O95819|rcsb pdb:4OBO|rcsb pdb:4OBP|rcsb pdb:4OBQ|rcsb pdb:4RVT|rcsb pdb:4U3Y|rcsb pdb:4U3Z|rcsb pdb:4U40|rcsb pdb:4U41|rcsb pdb:4U42|rcsb pdb:4U43|rcsb pdb:4U44|rcsb pdb:4U45|rcsb pdb:4ZK5|rcsb pdb:4ZP5|rcsb pdb:5DI1|rcsb pdb:5J95|rcsb pdb:5W5Q|reactome:R-HSA-2559580|ensembl:ENSG00000071054(gene)|refseq:NP_001229488.1|refseq:NP_004825.3|refseq:NP_663720.1|ensembl:ENSP00000314363|ensembl:ENST00000350878|ensembl:ENSP00000343658|ensembl:ENST00000634702|ensembl:ENSP00000489579 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:wEXGp6vM4HhwldyeQJKvEdilMpQ9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P23490 - intact:EBI-715902|uniprotkb:Q5T869|uniprotkb:Q5XKF8|ensembl:ENSP00000357731 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:lori_human(display_long)|uniprotkb:LORICRIN(gene name)|psi-mi:LORICRIN(display_short)|uniprotkb:LOR(gene name synonym)|uniprotkb:LRN(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000418.2|ensembl:ENSG00000203782(gene)|ensembl:ENST00000368742(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|interpro:IPR031700|mint:P23490|reactome:R-HSA-6809371 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:ISIQk0W6vIOc/aityV1tebyaTE89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q13136 - intact:EBI-745426|uniprotkb:Q8N4I2|uniprotkb:Q14567|uniprotkb:A6NLE3|uniprotkb:Q13135|intact:EBI-28983934|ensembl:ENSP00000253925 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:lipa1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1(gene name synonym)|uniprotkb:LAR-interacting protein 1(gene name synonym)|uniprotkb:PPFIA1(gene name)|psi-mi:PPFIA1(display_short)|uniprotkb:LIP1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003617.1|refseq:NP_803172.1|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|ensembl:ENSP00000253925|ensembl:ENST00000389547|ensembl:ENSP00000374198|ensembl:ENSG00000131626(gene)|ensembl:ENST00000253925(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030438|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:Q13136|rcsb pdb:1N7F|reactome:R-HSA-181429|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|reactome:R-HSA-181430|reactome:R-HSA-210500 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:uLKfBaRJRh4tvNCQ8WP7rnfrmrU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9Y383 - intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P05455 - intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P05556 - intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P30740 - intact:EBI-2831526|uniprotkb:Q53FB9|uniprotkb:A8K5L2|uniprotkb:Q5W0E1|uniprotkb:Q9UDF8|uniprotkb:B4DNT0|ensembl:ENSP00000370115 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ileu_human(display_long)|uniprotkb:SERPINB1(gene name)|psi-mi:SERPINB1(display_short)|uniprotkb:ELANH2(gene name synonym)|uniprotkb:MNEI(gene name synonym)|uniprotkb:PI2(gene name synonym)|uniprotkb:Monocyte/neutrophil elastase inhibitor(gene name synonym)|uniprotkb:Peptidase inhibitor 2(gene name synonym)|uniprotkb:Serpin B1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:XP_011512635.1|refseq:XP_011512636.1|ensembl:ENSG00000021355(gene)|ensembl:ENST00000380739(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015557(Protease inhibitor I4, serpin B1)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:4GA7|reactome:R-HSA-6798695|refseq:NP_109591.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:5IolAmA+BrS4XHZZEQgf05kA4pE9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P01591 - intact:EBI-2866826|ensembl:ENSP00000254801|ensembl:ENSP00000426687 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:igj_human(display_long)|uniprotkb:JCHAIN(gene name)|psi-mi:JCHAIN(display_short)|uniprotkb:IGCJ(gene name synonym)|uniprotkb:IGJ(gene name synonym)|uniprotkb:Joining chain of multimeric IgA and IgM(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:XP_011530227.1|refseq:XP_011530228.1|refseq:NP_653247.1|refseq:XP_006714274.1|refseq:XP_006714275.1|ensembl:ENSG00000132465(gene)|ensembl:ENST00000254801(transcript)|ensembl:ENST00000510437(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006955"(immune response)|go:"GO:0006959"(humoral immune response)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019862"(IgA binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071748"(monomeric IgA immunoglobulin complex)|go:"GO:0071750"(dimeric IgA immunoglobulin complex)|go:"GO:0071751"(secretory IgA immunoglobulin complex)|go:"GO:0071752"(secretory dimeric IgA immunoglobulin complex)|go:"GO:0071756"(pentameric IgM immunoglobulin complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR024110|rcsb pdb:6KXS|rcsb pdb:6LX3|rcsb pdb:6LXW|rcsb pdb:6UE7|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|rcsb pdb:7K0C|reactome:R-HSA-202733|reactome:R-HSA-2168880 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:0LaSqZzqBXZZZx+9zeTse0tZOdo9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O60573 - intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q14197 - intact:EBI-1049413|uniprotkb:Q53HM7|uniprotkb:Q53Y11|uniprotkb:B2RAD1|ensembl:ENSP00000301585 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ict1_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL62(gene name synonym)|uniprotkb:MRPL58(gene name)|psi-mi:MRPL58(display_short)|uniprotkb:39S ribosomal protein L58, mitochondrial(gene name synonym)|uniprotkb:DS1(gene name synonym)|uniprotkb:Digestion substraction 1(gene name synonym)|uniprotkb:ICT1(gene name synonym)|uniprotkb:Immature colon carcinoma transcript 1 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001536.1|refseq:NP_001290194.1|ensembl:ENSG00000167862(gene)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0016150"(translation release factor activity, codon nonspecific)|go:"GO:0070126"(mitochondrial translational termination)|interpro:IPR000352(Class I peptide chain release factor)|mint:Q14197|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7NQL|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENST00000301585(transcript) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:7VHUOV/AvCr5g+TkvFNQqxp2kjM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O60725 - intact:EBI-11721771|ensembl:ENSP00000343552|uniprotkb:Q6FHT0 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:icmt_human(display_long)|uniprotkb:ICMT(gene name)|psi-mi:ICMT(display_short)|uniprotkb:PCCMT(gene name synonym)|uniprotkb:Isoprenylcysteine carboxylmethyltransferase(gene name synonym)|uniprotkb:Prenylated protein carboxyl methyltransferase(gene name synonym)|uniprotkb:Prenylcysteine carboxyl methyltransferase(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0006481"(C-terminal protein methylation)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007269(Isoprenylcysteine carboxyl methyltransferase)|interpro:IPR025770|reactome:R-HSA-163841|reactome:R-HSA-9648002|ensembl:ENSG00000116237(gene)|ensembl:ENST00000343813(transcript)|go:"GO:0003880"(protein C-terminal carboxyl O-methyltransferase activity)|go:"GO:0004671"(protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|refseq:NP_036537.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:MOmsQsB41kb1HcjhwTlROaZ+XFA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9BUJ2 - intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:IahA7SVR1NmvldrWKQlAwApinQE9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P22830 - intact:EBI-1390356|uniprotkb:Q8IXN1|uniprotkb:Q8NAN0|uniprotkb:A8KA72|ensembl:ENSP00000262093 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hemh_human(display_long)|uniprotkb:Protoheme ferro-lyase(gene name synonym)|uniprotkb:Heme synthase(gene name synonym)|uniprotkb:FECH(gene name)|psi-mi:FECH(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000131.2|refseq:NP_001012533.1|dip:DIP-39632N|ensembl:ENSG00000066926(gene)|ensembl:ENST00000262093(transcript)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010288"(response to lead ion)|go:"GO:0017085"(response to insecticide)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045471"(response to ethanol)|go:"GO:0046501"(protoporphyrinogen IX metabolic process)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051597"(response to methylmercury)|go:"GO:0070541"(response to platinum ion)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|interpro:IPR033644|interpro:IPR033659|rcsb pdb:1HRK|rcsb pdb:2HRC|rcsb pdb:2HRE|rcsb pdb:2PNJ|rcsb pdb:2PO5|rcsb pdb:2PO7|rcsb pdb:2QD1|rcsb pdb:2QD2|rcsb pdb:2QD3|rcsb pdb:2QD4|rcsb pdb:2QD5|rcsb pdb:3AQI|rcsb pdb:3HCN|rcsb pdb:3HCO|rcsb pdb:3HCP|rcsb pdb:3HCR|rcsb pdb:3W1W|rcsb pdb:4F4D|rcsb pdb:4KLA|rcsb pdb:4KLC|rcsb pdb:4KLR|rcsb pdb:4KMM|rcsb pdb:4MK4|reactome:R-HSA-189451 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Rh4ulxUAnCedNUVAABAhY4iOnuo9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q6Y1H2 - intact:EBI-530257|ensembl:ENSP00000373153 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hacd2_human(display_long)|uniprotkb:HACD2(gene name)|psi-mi:HACD2(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 2(gene name synonym)|uniprotkb:PTPLB(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like member B(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_940684.1|ensembl:ENSG00000206527(gene)|ensembl:ENST00000383657(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0080023"(3R-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|reactome:R-HSA-75876 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:GBsqZyiJ8Tc3IuibyZcz8MOnlao9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P07305 - intact:EBI-725224|uniprotkb:Q6FG88|uniprotkb:Q8N6R3|uniprotkb:B4DRD6|uniprotkb:B2R6I0|ensembl:ENSP00000344504 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:h10_human(display_long)|uniprotkb:H1-0(gene name)|psi-mi:H1-0(display_short)|uniprotkb:H1F0(gene name synonym)|uniprotkb:H1FV(gene name synonym)|uniprotkb:Histone H1'(gene name synonym)|uniprotkb:"Histone H1(0)"(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_005309.1|ensembl:ENSG00000189060(gene)|ensembl:ENST00000340857(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P07305|rcsb pdb:6HQ1|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6N88|rcsb pdb:6N89|rcsb pdb:7DBP|rcsb pdb:7K5X|reactome:R-HSA-140342|reactome:R-HSA-2559584|dip:DIP-41775N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:7ir9Jz/gNZypmWkTopCusDQFEhs9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O43824 - intact:EBI-10970033|ensembl:ENSP00000316598|uniprotkb:Q5HYX8|uniprotkb:Q53F77|uniprotkb:H0Y2S1 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:gtpb6_human(display_long)|uniprotkb:GTPBP6(gene name)|psi-mi:GTPBP6(display_short)|uniprotkb:PGPL(gene name synonym)|uniprotkb:Pseudoautosomal GTP-binding protein-like(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_036359.3|ensembl:ENSG00000178605(gene)|ensembl:ENST00000326153(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR006073(GTP1/OBG)|interpro:IPR016496(GTP-binding protein, HflX)|interpro:IPR025121|interpro:IPR027417|interpro:IPR030394|interpro:IPR032305|interpro:IPR042108|rcsb pdb:7OF2|rcsb pdb:7OF4|rcsb pdb:7OF6 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:NlrtEAFZqVgQqV84Z6unM4jKWI89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P09211 - intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607|uniprotkb:Q5TZY3 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000843.1|ensembl:ENSG00000084207(gene)|go:"GO:0000302"(response to reactive oxygen species)|ensembl:ENST00000398606(transcript)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009890"(negative regulation of biosynthetic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0035732"(nitric oxide storage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7GSS|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O95249 - intact:EBI-3235244|ensembl:ENSP00000225724|uniprotkb:O75392|uniprotkb:J3KST5 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:gosr1_human(display_long)|uniprotkb:GOSR1(gene name)|psi-mi:GOSR1(display_short)|uniprotkb:GS28(gene name synonym)|uniprotkb:28 kDa Golgi SNARE protein(gene name synonym)|uniprotkb:28 kDa cis-Golgi SNARE p28(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000108587(gene)|ensembl:ENST00000225724(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|mint:O95249|reactome:R-HSA-6807878|reactome:R-HSA-6811438|refseq:NP_001007025.1|refseq:NP_001007026.1|refseq:NP_004862.1|refseq:XP_005258129.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:zebOuVPnYg5z3XqCa5rMI2IR/jY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q92820 - intact:EBI-3045534|ensembl:ENSP00000260118 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ggh_human(display_long)|uniprotkb:GGH(gene name)|psi-mi:GGH(display_short)|uniprotkb:Conjugase(gene name synonym)|uniprotkb:GH(gene name synonym)|uniprotkb:Gamma-Glu-X carboxypeptidase(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000137563(gene)|ensembl:ENST00000260118(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032868"(response to insulin)|go:"GO:0034722"(gamma-glutamyl-peptidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0046900"(tetrahydrofolylpolyglutamate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070500"(poly-gamma-glutamate metabolic process)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR011697(Peptidase C26)|interpro:IPR015527(Peptidase C26, gamma-glutamyl hydrolase)|interpro:IPR029062|mint:Q92820|rcsb pdb:1L9X|reactome:R-HSA-6798695|refseq:NP_003869.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:QjPbv+fLXWnf6gmW2PsXVuyatR49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8TB36 - intact:EBI-11110431|uniprotkb:E7FJF4|uniprotkb:E7FJF3|uniprotkb:A8K957|ensembl:ENSP00000220822 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:gdap1_human(display_long)|uniprotkb:GDAP1(gene name)|psi-mi:GDAP1(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001035808.1|refseq:NP_061845.2|ensembl:ENSG00000104381(gene)|ensembl:ENST00000220822(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0071305"(cellular response to vitamin D)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR034336|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:7AIA|rcsb pdb:7ALM|reactome:R-HSA-9603798 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:OrA2TaUsWoSfp/jX35NAkdILKek9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q6ZN66 - intact:EBI-20864397|ensembl:ENSP00000359485|uniprotkb:A2RRM3|uniprotkb:Q6ZN86|uniprotkb:Q7Z3F0 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:gbp6_human(display_long)|uniprotkb:GTP-binding protein 6(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 6(gene name synonym)|uniprotkb:GBP6(gene name)|psi-mi:GBP6(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000183347(gene)|ensembl:ENST00000370456(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006955"(immune response)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|reactome:R-HSA-877300|refseq:NP_940862.2|refseq:XP_011539137.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:z2Ly6alzS3mF12JkKwFARNNpbv49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P63244 - intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P50440 - intact:EBI-2552594|uniprotkb:Q53EQ4|uniprotkb:B4DH99|uniprotkb:B4DPI3|ensembl:ENSP00000379895 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:gatm_human(display_long)|uniprotkb:AGAT(gene name synonym)|uniprotkb:"L-arginine:glycine amidinotransferase"(gene name synonym)|uniprotkb:Transamidinase(gene name synonym)|uniprotkb:GATM(gene name)|psi-mi:GATM(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001473.1|ensembl:ENSG00000171766(gene)|ensembl:ENST00000396659(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006600"(creatine metabolic process)|go:"GO:0006601"(creatine biosynthetic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007611"(learning or memory)|go:"GO:0014889"(muscle atrophy)|go:"GO:0015067"(amidinotransferase activity)|go:"GO:0015068"(glycine amidinotransferase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR033195|rcsb pdb:1JDW|rcsb pdb:1JDX|rcsb pdb:2JDW|rcsb pdb:2JDX|rcsb pdb:3JDW|rcsb pdb:4JDW|rcsb pdb:5JDW|rcsb pdb:6JDW|rcsb pdb:7JDW|rcsb pdb:8JDW|rcsb pdb:9JDW|reactome:R-HSA-71288 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:FYkmOSpHilJ5gCuPd5PQ3dIQiy89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96CU9 - intact:EBI-372820|uniprotkb:Q71MG0|uniprotkb:Q9BU39|uniprotkb:Q9UKY9|uniprotkb:B3KN84|uniprotkb:B4DHU2|ensembl:ENSP00000263578 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:fxrd1_human(display_long)|uniprotkb:FP634(orf name)|uniprotkb:FOXRED1(gene name)|psi-mi:FOXRED1(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_060017.1|refseq:XP_006718944.1|refseq:XP_016873492.1|refseq:XP_016873493.1|refseq:XP_016873494.1|ensembl:ENSG00000110074(gene)|ensembl:ENST00000263578(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR036188 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:cAeSafbcQmh6XLk/IrNfsD+KHtA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P31513 - intact:EBI-12361463|ensembl:ENSP00000356729|uniprotkb:B2R816|uniprotkb:Q14854|uniprotkb:Q8N5N5 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:fmo3_human(display_long)|uniprotkb:FMO3(gene name)|psi-mi:FMO3(display_short)|uniprotkb:Dimethylaniline oxidase 3(gene name synonym)|uniprotkb:FMO II(gene name synonym)|uniprotkb:FMO form 2(gene name synonym)|uniprotkb:Hepatic flavin-containing monooxygenase 3(gene name synonym)|uniprotkb:Trimethylamine monooxygenase(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000007933(gene)|ensembl:ENST00000367755(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0004499"(N,N-dimethylaniline monooxygenase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034899"(trimethylamine monooxygenase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|interpro:IPR000960(Flavin-containing monooxygenase FMO)|interpro:IPR002255("Flavin-containing monooxygenase (FMO) 3")|interpro:IPR020946|interpro:IPR036188|reactome:R-HSA-217271|reactome:R-HSA-5579019|refseq:NP_001002294.1|refseq:NP_001306102.1|refseq:NP_001306103.1|refseq:NP_008825.4 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:y2ccfOGjn7Z1A6kFUnxrvQkeAEQ9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q13643 - intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q53R41 - intact:EBI-3957005|uniprotkb:Q8N583|uniprotkb:Q8TEA9|uniprotkb:Q96JM5|uniprotkb:Q96N71|uniprotkb:Q9H6T4|ensembl:ENSP00000400513 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:fakd1_human(display_long)|uniprotkb:FASTKD1(gene name)|psi-mi:FASTKD1(display_short)|uniprotkb:KIAA1800(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_078898.3|refseq:NP_001268405.1|refseq:NP_001308975.1|refseq:NP_001308977.1|refseq:NP_001308978.1|refseq:XP_016860400.1|ensembl:ENSG00000138399(gene)|ensembl:ENST00000453153(transcript)|go:"GO:0000959"(mitochondrial RNA metabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:eizlBY2w9CXu4y4WE8R4QOUWoXA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q6ZRV2 - intact:EBI-2556538|intact:EBI-2558430|uniprotkb:Q8N4W0|uniprotkb:A0JLS2|intact:EBI-28968834|ensembl:ENSP00000373565|ensembl:ENSP00000478790 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:fa83h_human(display_long)|uniprotkb:FAM83H(gene name)|psi-mi:FAM83H(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_940890.3|ensembl:ENSP00000373565|ensembl:ENSP00000478790|ensembl:ENSG00000180921(gene)|ensembl:ENSG00000273889(gene)|ensembl:ENST00000388913(transcript)|ensembl:ENST00000612192(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007165"(signal transduction)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:1990254"(keratin filament binding)|interpro:IPR012461(Protein of unknown function DUF1669)|go:"GO:0030335"(positive regulation of cell migration)|interpro:IPR041996|go:"GO:0031214"(biomineral tissue development)|mint:Q6ZRV2|go:"GO:0044380"(protein localization to cytoskeleton)|go:"GO:0019901"(protein kinase binding)|refseq:XP_005250946.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:CraAR+g1L497ZXCuetDTOHn8rUA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q15369 - intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8IYU8 - intact:EBI-3197790|ensembl:ENSP00000371811|uniprotkb:Q8N0T6|uniprotkb:Q8NAX8 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:micu2_human(display_long)|uniprotkb:MICU2(gene name)|psi-mi:MICU2(display_short)|uniprotkb:EF-hand domain-containing family member A1(gene name synonym)|uniprotkb:EFHA1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000165487(gene)|ensembl:ENST00000382374(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0034704"(calcium channel complex)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:1990246"(uniplex complex)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR039800|rcsb pdb:6AGH|rcsb pdb:6IIH|rcsb pdb:6K7Y|rcsb pdb:6LB7|rcsb pdb:6LB8|rcsb pdb:6LE5|rcsb pdb:6WDN|rcsb pdb:6WDO|rcsb pdb:6XJV|rcsb pdb:6XJX|rcsb pdb:6XQN|rcsb pdb:6XQO|reactome:R-HSA-8949215|reactome:R-HSA-8949664|refseq:NP_689939.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:qj7nAE+DvoW/RWlr4VWGSbhS6Mc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9Y2J2 - intact:EBI-310986|uniprotkb:O95713|uniprotkb:Q9BRP5|ensembl:ENSP00000343158|uniprotkb:B7Z4I5|uniprotkb:F5GX05 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:e41l3_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short)|uniprotkb:DAL1(gene name synonym)|uniprotkb:KIAA0987(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_036439.2|refseq:NP_001268462.1|refseq:NP_001268463.1|refseq:NP_001268464.1|ensembl:ENSG00000082397(gene)|ensembl:ENST00000341928(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030054"(cell junction)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043217"(myelin maintenance)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9Y2J2|rcsb pdb:2HE7|rcsb pdb:3BIN|rcsb pdb:5RYM|rcsb pdb:5RYN|rcsb pdb:5RYO|rcsb pdb:5RYP|rcsb pdb:5RYQ|rcsb pdb:5RYR|rcsb pdb:5RYS|rcsb pdb:5RYT|rcsb pdb:5RYU|rcsb pdb:5RYV|rcsb pdb:5RYW|rcsb pdb:5RYX|rcsb pdb:5RYY|rcsb pdb:5RYZ|rcsb pdb:5RZ0|rcsb pdb:5RZ1|rcsb pdb:5RZ2|rcsb pdb:5RZ3|rcsb pdb:5RZ4|rcsb pdb:5RZ5|rcsb pdb:5RZ6|rcsb pdb:5RZ7|rcsb pdb:5RZ8|rcsb pdb:5RZ9|rcsb pdb:5RZA|rcsb pdb:5RZB|rcsb pdb:5RZC|rcsb pdb:5RZD|rcsb pdb:5RZE|rcsb pdb:5RZF|rcsb pdb:5RZG|rcsb pdb:5RZH|rcsb pdb:5RZI|rcsb pdb:5RZJ|rcsb pdb:5RZK|rcsb pdb:5RZL|rcsb pdb:5RZM|rcsb pdb:5RZN|rcsb pdb:5RZO|rcsb pdb:5RZP|rcsb pdb:5RZQ|rcsb pdb:5RZR|rcsb pdb:5RZS|rcsb pdb:5RZT|rcsb pdb:5RZU|rcsb pdb:5RZV|rcsb pdb:5RZW|rcsb pdb:5RZX|rcsb pdb:5RZY|rcsb pdb:5RZZ|rcsb pdb:5S00|rcsb pdb:6IBE|reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:XP_016881125.1|dip:DIP-17035N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Uwq5dqLRdgFLPBhXZROSRJstl709606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O60762 - intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:znbNDwp7t238ByanlbQzsTMvwTY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UBS3 - intact:EBI-713124|ensembl:ENSP00000249356 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:dnjb9_human(display_long)|uniprotkb:Microvascular endothelial differentiation gene 1 protein(gene name synonym)|uniprotkb:DNAJB9(gene name)|psi-mi:DNAJB9(display_short)|uniprotkb:MDG1(gene name synonym)|uniprotkb:UNQ743/PRO1471(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 4(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000128590(gene)|ensembl:ENST00000249356(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|rcsb pdb:2CTR|reactome:R-HSA-381038|go:"GO:0051787"(misfolded protein binding)|refseq:NP_036460.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:yP4vHOlqhtk5d0T2FCSfRkbRdrY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96GG9 - intact:EBI-740086|uniprotkb:B2RB37|uniprotkb:Q7L3G9|uniprotkb:Q8TEX7|uniprotkb:Q9H6M1|uniprotkb:Q9HCT3|ensembl:ENSP00000292782 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:dcnl1_human(display_long)|uniprotkb:DCUN1D1(gene name)|psi-mi:DCUN1D1(display_short)|uniprotkb:DCUN1L1(gene name synonym)|uniprotkb:RP42(gene name synonym)|uniprotkb:SCCRO(gene name synonym)|uniprotkb:Defective in cullin neddylation protein 1-like protein 1(gene name synonym)|uniprotkb:DCUN1 domain-containing protein 1(gene name synonym)|uniprotkb:Squamous cell carcinoma-related oncogene(gene name synonym)|uniprotkb:DCN1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_065691.2|ensembl:ENSG00000043093(gene)|ensembl:ENST00000292782(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032182"(ubiquitin-like protein binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000434"(regulation of protein neddylation)|go:"GO:2000436"(positive regulation of protein neddylation)|interpro:IPR005176(Protein of unknown function DUF298)|interpro:IPR009060(UBA-like)|interpro:IPR014764(Defective in cullin neddylation)|interpro:IPR042460|rcsb pdb:3TDU|rcsb pdb:3TDZ|rcsb pdb:4P5O|rcsb pdb:5UFI|rcsb pdb:5V83|rcsb pdb:5V86|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|rcsb pdb:6B5Q|rcsb pdb:6BG3|rcsb pdb:6BG5|rcsb pdb:6P5V|rcsb pdb:6P5W|rcsb pdb:6XOL|rcsb pdb:6XOM|rcsb pdb:6XON|rcsb pdb:6XOO|rcsb pdb:6XOP|rcsb pdb:6XOQ|reactome:R-HSA-8951664|rcsb pdb:5V88|refseq:NP_001295030.1|dip:DIP-42121N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:TiHJulV7MphxjMdNbVvrlQKkAPo9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P16989 - intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P01037 - intact:EBI-1056240|uniprotkb:Q96LE6|uniprotkb:Q9UCQ6|ensembl:ENSP00000305731|ensembl:ENSP00000381439 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cytn_human(display_long)|uniprotkb:CST1(gene name)|psi-mi:CST1(display_short)|uniprotkb:Cystatin-1(gene name synonym)|uniprotkb:Salivary cystatin-SA-1(gene name synonym)|uniprotkb:Cystain-SA-I(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001889.2|ensembl:ENSG00000170373(gene)|ensembl:ENST00000304749(transcript)|ensembl:ENST00000398402(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR018073|mint:P01037 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Ex6G/NAuwbF8h/4r104dm89B36M9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P01034 - intact:EBI-948622|ensembl:ENSP00000366124|ensembl:ENSP00000381446|ensembl:ENSP00000381448|uniprotkb:Q6FGW9|uniprotkb:B2R5J9|uniprotkb:D3DW42 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cytc_human(display_long)|uniprotkb:Cystatin-3(gene name synonym)|uniprotkb:Neuroendocrine basic polypeptide(gene name synonym)|uniprotkb:Gamma-trace(gene name synonym)|uniprotkb:Post-gamma-globulin(gene name synonym)|uniprotkb:CST3(gene name)|psi-mi:CST3(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0060313"(negative regulation of blood vessel remodeling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR018073|rcsb pdb:1G96|rcsb pdb:1R4C|rcsb pdb:1TIJ|rcsb pdb:3GAX|rcsb pdb:3NX0|rcsb pdb:3PS8|rcsb pdb:3QRD|rcsb pdb:3S67|rcsb pdb:3SVA|rcsb pdb:6ROA|rcsb pdb:6RPV|reactome:R-HSA-381426|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-977225|ensembl:ENSG00000101439(gene)|ensembl:ENST00000376925(transcript)|ensembl:ENST00000398409(transcript)|ensembl:ENST00000398411(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002020"(protease binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0010711"(negative regulation of collagen catabolic process)|go:"GO:0010716"(negative regulation of extracellular matrix disassembly)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0042802"(identical protein binding)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0060311"(negative regulation of elastin catabolic process)|refseq:NP_000090.1|refseq:NP_001275543.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:UJT8nc0DeqGBXeRiy8RnrB1tKGw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P04080 - intact:EBI-1051966|ensembl:ENSP00000291568 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cytb_human(display_long)|uniprotkb:Stefin-B(gene name synonym)|uniprotkb:Liver thiol proteinase inhibitor(gene name synonym)|uniprotkb:CPI-B(gene name synonym)|uniprotkb:CSTB(gene name)|psi-mi:CSTB(display_short)|uniprotkb:CST6(gene name synonym)|uniprotkb:STFB(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000091.1|ensembl:ENSG00000160213(gene)|ensembl:ENST00000291568(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|interpro:IPR018073|mint:P04080|rcsb pdb:1STF|rcsb pdb:2OCT|rcsb pdb:4N6V|reactome:R-HSA-6798695 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:KwR0XgOq6SeHdqxriNE8xIUMmUo9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O43169 - intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9BSF4 - intact:EBI-10974729|ensembl:ENSP00000270502|uniprotkb:Q96EY6|uniprotkb:Q96IT8 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tim29_human(display_long)|uniprotkb:TIMM29(gene name)|psi-mi:TIMM29(display_short)|uniprotkb:c19orf52(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_612367.1|ensembl:ENSG00000142444(gene)|ensembl:ENST00000270502(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042721"(TIM22 mitochondrial import inner membrane insertion complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0140318"(protein transporter activity)|interpro:IPR019322|rcsb pdb:7CGP go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:9RRT6AC0o31q81ETOTJgq3Gk+2E9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UBG3 - intact:EBI-3197866|ensembl:ENSP00000271835|uniprotkb:B2RE60|uniprotkb:Q8N613 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:crnn_human(display_long)|uniprotkb:CRNN(gene name)|psi-mi:CRNN(display_short)|uniprotkb:C1orf10(gene name synonym)|uniprotkb:DRC1(gene name synonym)|uniprotkb:PDRC1(gene name synonym)|uniprotkb:SEP53(gene name synonym)|uniprotkb:53 kDa putative calcium-binding protein(gene name synonym)|uniprotkb:53 kDa squamous epithelial-induced stress protein(gene name synonym)|uniprotkb:58 kDa heat shock protein(gene name synonym)|uniprotkb:Squamous epithelial heat shock protein 53(gene name synonym)|uniprotkb:Tumor-related protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000143536(gene)|ensembl:ENST00000271835(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009408"(response to heat)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR026792|interpro:IPR034325|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|refseq:NP_057274.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:uRYaJ+xbt2s9hXiVj5DzlS6SKT09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O43809 - intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P13584 - intact:EBI-1052398|uniprotkb:Q8TD85|uniprotkb:Q8WWU9|uniprotkb:Q8WWV0|uniprotkb:Q1HBI2|uniprotkb:Q8WWF2|ensembl:ENSP00000271153 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cp4b1_human(display_long)|uniprotkb:CYPIVB1(gene name synonym)|uniprotkb:Cytochrome P450-HP(gene name synonym)|uniprotkb:CYP4B1(gene name)|psi-mi:CYP4B1(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000770.2|refseq:NP_001093242.1|ensembl:ENSG00000142973(gene)|ensembl:ENST00000271153(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0018879"(biphenyl metabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR036396|reactome:R-HSA-211935|reactome:R-HSA-211958|reactome:R-HSA-211979|reactome:R-HSA-2142691|go:"GO:0004497"(monooxygenase activity) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:nMXZ+cNec1O+ShKQwq2AkjOTTfU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P31146 - intact:EBI-1046676|ensembl:ENSP00000219150|ensembl:ENSP00000455552|uniprotkb:Q2YD73|uniprotkb:B2RBL1 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cor1a_human(display_long)|uniprotkb:Coronin-like protein p57(gene name synonym)|uniprotkb:Coronin-like protein A(gene name synonym)|uniprotkb:Tryptophan aspartate-containing coat protein(gene name synonym)|uniprotkb:CORO1A(gene name)|psi-mi:CORO1A(display_short)|uniprotkb:CORO1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001180262.1|refseq:NP_009005.1|ensembl:ENSG00000102879(gene)|ensembl:ENST00000219150(transcript)|ensembl:ENST00000570045(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031339"(negative regulation of vesicle fusion)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032796"(uropod organization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043320"(natural killer cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051126"(negative regulation of actin nucleation)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0061502"(early endosome to recycling endosome transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0045087"(innate immune response)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015049(Region of unknown function DUF1900)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR029508|interpro:IPR036322|mint:P31146|reactome:R-HSA-9636383|interpro:IPR019775|refseq:XP_011544016.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:p2NmQ7YE3FUzyW0Op4rLPLFaVVU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P50750 - intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O14735 - intact:EBI-358858|uniprotkb:Q6FGU1|uniprotkb:Q6ZN70|ensembl:ENSP00000219789|ensembl:ENSP00000454453|ensembl:ENSP00000457339|uniprotkb:B4DUV0|uniprotkb:H3BTV1 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cdipt_human(display_long)|uniprotkb:CDIPT(gene name)|psi-mi:CDIPT(display_short)|uniprotkb:PIS(gene name synonym)|uniprotkb:PIS1(gene name synonym)|uniprotkb:Phosphatidylinositol synthase(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001273514.1|refseq:NP_006310.1|ensembl:ENSG00000103502(gene)|ensembl:ENST00000219789(transcript)|ensembl:ENST00000569956(transcript)|ensembl:ENST00000570016(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043178"(alcohol binding)|go:"GO:0046341"(CDP-diacylglycerol metabolic process)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-HSA-1483226|dip:DIP-54492N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:SIs1nKd3UxZREA2Sxl4MxxBNYvM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q16543 - intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:iajhitd2iEmd17KfpU/nMaKc4049606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P13987 - intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8N5G0 - intact:EBI-6570855|ensembl:ENSP00000427407|uniprotkb:C9JYT8|uniprotkb:Q9BRT5 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sim20_human(display_long)|uniprotkb:SMIM20(gene name)|psi-mi:SMIM20(display_short)|uniprotkb:C4orf52(gene name synonym)|uniprotkb:MITRAC7(gene name synonym)|uniprotkb:Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000250317(gene)|ensembl:ENST00000506197(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR027917|mint:Q8N5G0|refseq:NP_001138904.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:yqRjpvlmOpU7RfsXACpQ7ytSFZE9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8N4T8 - intact:EBI-10897344|uniprotkb:Q8WTW8|uniprotkb:Q96K93|ensembl:ENSP00000303525 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cbr4_human(display_long)|uniprotkb:CBR4(gene name)|psi-mi:CBR4(display_short)|uniprotkb:SDR45C1(gene name synonym)|uniprotkb:Quinone reductase CBR4(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 45C member 1(gene name synonym)|uniprotkb:3-ketoacyl-[acyl-carrier-protein] reductase beta subunit(gene name synonym)|uniprotkb:Carbonyl reductase family member 4(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_116172.2|rcsb pdb:4CQL|rcsb pdb:4CQM|reactome:R-HSA-75105|interpro:IPR036291|ensembl:ENSG00000145439(gene)|ensembl:ENST00000306193(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008753"("NADPH dehydrogenase (quinone) activity")|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0048038"(quinone binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0070402"(NADPH binding)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|go:"GO:1990204"(oxidoreductase complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:90umrT5u3VndeVMkAoOe8iewIJg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8WWC4 - intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q01518 - intact:EBI-2808398|ensembl:ENSP00000361878|ensembl:ENSP00000361883|ensembl:ENSP00000361891|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000131236(gene)|ensembl:ENST00000372792(transcript)|ensembl:ENST00000372797(transcript)|ensembl:ENST00000372805(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028415|interpro:IPR028417|go:"GO:0001667"(ameboidal-type cell migration)|interpro:IPR036222|interpro:IPR036223|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|refseq:XP_005270425.1|dip:DIP-62063N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." crc64:7789D1FAC0D1AB7B figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P27482 - intact:EBI-747537|uniprotkb:Q5SQI4|uniprotkb:B2R9V6|ensembl:ENSP00000315299 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:call3_human(display_long)|uniprotkb:Calmodulin-related protein NB-1(gene name synonym)|uniprotkb:CaM-like protein(gene name synonym)|uniprotkb:CALML3(gene name)|psi-mi:CALML3(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_005176.1|ensembl:ENSG00000178363(gene)|ensembl:ENST00000315238(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P27482|rcsb pdb:1GGZ go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:7yRRBYvsbUxzIvnYaNmaIJ42i5Y9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q13895 - intact:EBI-358049|uniprotkb:Q6P5W4|uniprotkb:Q86W44|uniprotkb:Q96IP8|ensembl:ENSP00000230340 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:byst_human(display_long)|uniprotkb:BYSL(gene name)|psi-mi:BYSL(display_short)|uniprotkb:ENP1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_004044.3|dip:DIP-50092N|ensembl:ENSG00000112578(gene)|ensembl:ENST00000230340(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045177"(apical part of cell)|go:"GO:1904749"(regulation of protein localization to nucleolus)|interpro:IPR007955(Bystin)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|reactome:R-HSA-6791226 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:QdpF9XYm2gFc5ZodqaGvqTM6XNk9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8WY22 - intact:EBI-359348|uniprotkb:Q8WY23|ensembl:ENSP00000340761|ensembl:ENSP00000500359 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:bri3b_human(display_long)|uniprotkb:BRI3BP(gene name)|psi-mi:BRI3BP(display_short)|uniprotkb:KG19(gene name synonym)|uniprotkb:Cervical cancer 1 proto-oncogene-binding protein KG19(gene name synonym)|uniprotkb:HCCRBP-1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_542193.3|ensembl:ENSG00000184992(gene)|ensembl:ENST00000341446(transcript)|ensembl:ENST00000672415(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR033367 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:O9epHcfM1m7xNvrm6ELo0fRRGV49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P56385 - intact:EBI-2270000|uniprotkb:Q0D2L9|ensembl:ENSP00000306003 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:atp5i_human(display_long)|uniprotkb:ATP5ME(gene name)|psi-mi:ATP5ME(display_short)|uniprotkb:ATP5I(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)|uniprotkb:ATP5K(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_009031.1|ensembl:ENSG00000169020(gene)|ensembl:ENST00000304312(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:P56385|reactome:R-HSA-163210|reactome:R-HSA-8949613 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:NYpqzWQYASXwSwU/BYDTMU2tJjI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q12797 - intact:EBI-2967294|ensembl:ENSP00000368767|uniprotkb:B4E2K4|uniprotkb:F5H667|uniprotkb:Q9NRI0|uniprotkb:Q9Y4J0|uniprotkb:Q9H2C4|uniprotkb:A6NDF4|uniprotkb:Q9NRI1|uniprotkb:A6NHI2|uniprotkb:B4DIC9|uniprotkb:B7ZM95|uniprotkb:E5RGP5|uniprotkb:Q6NXR7|uniprotkb:Q8TB28|uniprotkb:Q9H291|intact:EBI-8994140|uniprotkb:A0A0A0MSK8 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:asph_human(display_long)|uniprotkb:ASPH(gene name)|psi-mi:ASPH(display_short)|uniprotkb:Aspartate beta-hydroxylase(gene name synonym)|uniprotkb:Peptide-aspartate beta-dioxygenase(gene name synonym)|uniprotkb:BAH(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000198363(gene)|ensembl:ENST00000379454(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033198"(response to ATP)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0062101"(peptidyl-aspartic acid 3-dioxygenase activity)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR007803(Aspartyl/Asparaginyl beta-hydroxylase)|interpro:IPR007943(Aspartyl beta-hydroxylase, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5APA|rcsb pdb:5JQY|interpro:IPR019734|rcsb pdb:5JTC|interpro:IPR027443|interpro:IPR039038|rcsb pdb:5JZ6|mint:Q12797|rcsb pdb:5JZ8|rcsb pdb:5JZA|rcsb pdb:5JZU|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6QA5|rcsb pdb:6RK9|rcsb pdb:6YYU|rcsb pdb:6YYV|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|reactome:R-HSA-5578775|reactome:R-HSA-2672351|refseq:NP_001158222.1|refseq:NP_004309.2|refseq:NP_064549.1|refseq:NP_115855.1|refseq:NP_115856.1|refseq:NP_001158223.1|refseq:NP_001158225.1|refseq:NP_001158227.1|refseq:NP_001158228.1|refseq:NP_115857.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:8Sv1CuwqdVCK6/PF6kL0hkX3/tw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P61158 - intact:EBI-351428|uniprotkb:P32391|ensembl:ENSP00000263238|uniprotkb:Q53QM2 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_005712.1|ensembl:ENSG00000115091(gene)|ensembl:ENST00000263238(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O95154 - intact:EBI-748869|uniprotkb:Q86SR4|uniprotkb:Q8IVN6|uniprotkb:Q8N5V6|uniprotkb:Q8TAX1|uniprotkb:Q9NUC3|ensembl:ENSP00000355377 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ark73_human(display_long)|uniprotkb:AFB1 aldehyde reductase 2(gene name synonym)|uniprotkb:AKR7A3(gene name)|psi-mi:AKR7A3(display_short)|uniprotkb:AFAR2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_036199.2|ensembl:ENSG00000162482(gene)|ensembl:ENST00000361640(transcript)|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046223"(aflatoxin catabolic process)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR023210|interpro:IPR036812|rcsb pdb:2CLP|reactome:R-HSA-5423646 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:AaO++YDKdbqFs5RYgKtp2mcMrLI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P05089 - intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9BQE5 - intact:EBI-4290634|uniprotkb:B0QYK7|uniprotkb:Q5TH96|uniprotkb:O95915|uniprotkb:Q59GW9|uniprotkb:Q969T6|uniprotkb:Q9BT28|uniprotkb:Q9UGT1|uniprotkb:Q9UH10|intact:EBI-28986438|ensembl:ENSP00000249066|ensembl:ENSP00000351292 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:apol2_human(display_long)|uniprotkb:APOL2(gene name)|psi-mi:APOL2(display_short)|uniprotkb:Apolipoprotein L-II(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000128335(gene)|ensembl:ENST00000249066(transcript)|ensembl:ENST00000358502(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006953"(acute-phase response)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0060135"(maternal process involved in female pregnancy)|interpro:IPR008405(Apolipoprotein L)|refseq:XP_011528376.1|refseq:XP_011528377.1|refseq:XP_011528378.1|refseq:XP_011528379.1|refseq:XP_011528380.1|refseq:NP_112092.2|refseq:NP_663612.2|ensembl:ENSP00000249066|ensembl:ENSP00000351292 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:7nHWWzmsRPST/D9qi3UjMhAck589606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P05090 - intact:EBI-715495|uniprotkb:Q6IBG6|uniprotkb:B2R579|uniprotkb:D3DNW6|ensembl:ENSP00000345179 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:apod_human(display_long)|uniprotkb:APOD(gene name)|psi-mi:APOD(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001638.1|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048678"(response to axon injury)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060588"(negative regulation of lipoprotein lipid oxidation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:2000098"(negative regulation of smooth muscle cell-matrix adhesion)|go:"GO:2000405"(negative regulation of T cell migration)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002969(Apolipoprotein D)|interpro:IPR012674(Calycin)|interpro:IPR022271|interpro:IPR022272|interpro:IPR026222|mint:P05090|rcsb pdb:2APD|rcsb pdb:2HZQ|rcsb pdb:2HZR|reactome:R-HSA-804914|reactome:R-HSA-9029569|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|ensembl:ENSG00000189058(gene)|ensembl:ENST00000343267(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:eD7+u5/ZQ5vntlwrq6itkhCxZJU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9Y2T2 - intact:EBI-2371151|uniprotkb:Q5JQ12|uniprotkb:Q9H5L2|ensembl:ENSP00000347408|ensembl:ENSP00000361831 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ap3m1_human(display_long)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu-1(gene name synonym)|uniprotkb:AP3M1(gene name)|psi-mi:AP3M1(display_short)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:Mu3A-adaptin(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001307192.1|refseq:NP_001307193.1|refseq:NP_036227.1|refseq:NP_996895.1|ensembl:ENSG00000185009(gene)|ensembl:ENST00000355264(transcript)|ensembl:ENST00000372745(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|mint:Q9Y2T2|reactome:R-HSA-390471 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:VsXYkOxEite1RzT1YHCA6/U4gj09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O00203 - intact:EBI-1044383|ensembl:ENSP00000255194|uniprotkb:O00580|uniprotkb:Q7Z393|uniprotkb:Q9HD66|uniprotkb:E5RJ68|intact:EBI-10969499 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ap3b1_human(display_long)|uniprotkb:Adaptor protein complex AP-3 subunit beta-1(gene name synonym)|uniprotkb:Beta-3A-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta-1 large chain(gene name synonym)|uniprotkb:AP3B1(gene name)|psi-mi:AP3B1(display_short)|uniprotkb:ADTB3A(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta-1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0006464"(cellular protein modification process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007040"(lysosome organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016020"(membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032438"(melanosome organization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0090152"(establishment of protein localization to mitochondrial membrane involved in mitochondrial fission)|go:"GO:0098773"(skin epidermis development)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390|interpro:IPR029394|mint:O00203|reactome:R-HSA-432722|reactome:R-HSA-6802952|refseq:NP_003655.3|ensembl:ENSG00000132842(gene)|ensembl:ENST00000255194(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003016"(respiratory system process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|refseq:NP_001258698.1|dip:DIP-24208N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:+06UuQo62p9ALS7DiX+yKg7YRyg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q08AH3 - intact:EBI-21286556|ensembl:ENSP00000219054|ensembl:ENSP00000379411|ensembl:ENSP00000459451|ensembl:ENSP00000460349|uniprotkb:B3KTT9|uniprotkb:O75202 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:acs2a_human(display_long)|uniprotkb:Benzoate--CoA ligase(gene name synonym)|uniprotkb:ACSM2A(gene name)|psi-mi:ACSM2A(display_short)|uniprotkb:ACSM2(gene name synonym)|uniprotkb:MACS2(gene name synonym)|uniprotkb:Acyl-CoA synthetase medium-chain family member 2A(gene name synonym)|uniprotkb:Butyrate--CoA ligase 2A(gene name synonym)|uniprotkb:Butyryl-coenzyme A synthetase 2A(gene name synonym)|uniprotkb:Middle-chain acyl-CoA synthetase 2A(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000183747(gene)|ensembl:ENST00000219054(transcript)|ensembl:ENST00000396104(transcript)|ensembl:ENST00000573854(transcript)|ensembl:ENST00000575690(transcript)|go:"GO:0004321"(fatty-acyl-CoA synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0015645"(fatty acid ligase activity)|go:"GO:0018858"(benzoate-CoA ligase activity)|go:"GO:0036112"(medium-chain fatty-acyl-CoA metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0047760"(butyrate-CoA ligase activity)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0102391"(decanoate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|mint:Q08AH3|rcsb pdb:2WD9|rcsb pdb:3B7W|rcsb pdb:3C5E|rcsb pdb:3DAY|rcsb pdb:3EQ6|rcsb pdb:3GPC|reactome:R-HSA-177128|rcsb pdb:2VZE|refseq:NP_001295101.1|refseq:NP_001295883.1|refseq:XP_016878412.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:DwWZXd/Ir5INoGoRwyGGGasUlnw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8N2K0 - intact:EBI-6269657|uniprotkb:A6NED4|uniprotkb:A6NJ90|uniprotkb:A8K450|uniprotkb:B4DE71|uniprotkb:Q5T710|uniprotkb:Q5T711|uniprotkb:Q96CR1|uniprotkb:Q9BX05|uniprotkb:Q9NPX7|uniprotkb:Q9UFV6|ensembl:ENSP00000341408 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:abd12_human(display_long)|uniprotkb:ABHD12(gene name)|psi-mi:ABHD12(display_short)|uniprotkb:C20orf22(gene name synonym)|uniprotkb:Abhydrolase domain-containing protein 12(gene name synonym)|uniprotkb:2-arachidonoylglycerol hydrolase ABHD12(gene name synonym)|uniprotkb:Monoacylglycerol lipase ABHD12(gene name synonym)|uniprotkb:Oxidized phosphatidylserine lipase ABHD12(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001035937.1|refseq:NP_056415.1|ensembl:ENSP00000341408|ensembl:ENST00000376542|ensembl:ENSP00000365725|ensembl:ENSG00000100997(gene)|ensembl:ENST00000339157(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006660"(phosphatidylserine catabolic process)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0046464"(acylglycerol catabolic process)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0052651"(monoacylglycerol catabolic process)|interpro:IPR022742|interpro:IPR026605|interpro:IPR029058|mint:Q8N2K0|reactome:R-HSA-426048 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:l5KeOxi83Cng20JUGy7ybEtoCPg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P56378 - intact:EBI-22217047|ensembl:ENSP00000286953|ensembl:ENSP00000450894|ensembl:ENSP00000452133|uniprotkb:B2R588|uniprotkb:G3V5Q3|uniprotkb:Q86TT7 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:atp68_human(display_long)|uniprotkb:ATP5MJ(gene name)|psi-mi:ATP5MJ(display_short)|uniprotkb:6.8 kDa mitochondrial proteolipid protein(gene name synonym)|uniprotkb:ATP synthase membrane subunit 6.8PL(gene name synonym)|uniprotkb:ATP5MPL(gene name synonym)|uniprotkb:C14orf2(gene name synonym)|uniprotkb:MP68(gene name synonym)|uniprotkb:PRO1574(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000156411(gene)|ensembl:ENST00000286953(transcript)|ensembl:ENST00000554880(transcript)|ensembl:ENST00000557040(transcript)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR012574(Mitochondrial proteolipid)|refseq:NP_001120865.1|refseq:NP_004885.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:JvKEWt6GrHZahEvIWlqCFeO5MNo9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P31947 - intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q14160 - intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UMS4 - intact:EBI-395746|ensembl:ENSP00000227524 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:prp19_human(display_long)|uniprotkb:PRPF19(gene name)|psi-mi:PRPF19(display_short)|uniprotkb:PRP19/PSO4 homolog(gene name synonym)|uniprotkb:Nuclear matrix protein 200(gene name synonym)|uniprotkb:Senescence evasion factor(gene name synonym)|uniprotkb:NMP200(gene name synonym)|uniprotkb:PRP19(gene name synonym)|uniprotkb:SNEV(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000110107(gene)|ensembl:ENST00000227524(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005819"(spindle)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_055317.1|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR038959|mint:Q9UMS4|rcsb pdb:4LG8|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|dip:DIP-32978N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:5TseaFcCOVVWjJeMF/H7k29nd3c9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P63092 - intact:EBI-1047114|uniprotkb:P04895|uniprotkb:Q12927|uniprotkb:Q5JWD2|uniprotkb:Q5JWD4|uniprotkb:Q5JWD5|uniprotkb:Q6NR75|uniprotkb:Q6NXS0|uniprotkb:Q8TBC0|uniprotkb:Q96H70|uniprotkb:Q14433|uniprotkb:Q32P26|uniprotkb:E1P5G5|ensembl:ENSP00000360126|uniprotkb:A6NI00|intact:EBI-10977858 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:gnas2_human(display_long)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:GSP(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001070958.1|refseq:NP_001296769.1|refseq:NP_536350.2|refseq:NP_000507.1|refseq:NP_001070956.1|refseq:NP_001070957.1|ensembl:ENSG00000087460(gene)|ensembl:ENST00000371085(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0048589"(developmental growth)|go:"GO:0050890"(cognition)|go:"GO:0060348"(bone development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63092|rcsb pdb:5G53|rcsb pdb:5UZ7|rcsb pdb:5VAI|rcsb pdb:6AU6|rcsb pdb:6B3J|rcsb pdb:6E3Y|rcsb pdb:6E67|rcsb pdb:6EG8|rcsb pdb:6GDG|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LPB|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6ORV|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VN7|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XOX|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7BPH|rcsb pdb:7BW0|rcsb pdb:7BZ2|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7D7M|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7KH0|rcsb pdb:7LCI|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|reactome:R-HSA-163359|reactome:R-HSA-164378|reactome:R-HSA-381676|reactome:R-HSA-392851|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821|refseq:NP_536351.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:fUnrdxwx4bBAqE3iO2cCB3UInyg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q09666 - intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:u1oecAyIihgxzfTz0jholE8wksA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8IVH4 - intact:EBI-10714945|uniprotkb:B3KX40|uniprotkb:Q495G7|ensembl:ENSP00000442284|ensembl:ENSP00000497008|ensembl:ENSP00000497046|ensembl:ENSP00000497680|ensembl:ENSP00000506503 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:mmaa_human(display_long)|uniprotkb:MMAA(gene name)|psi-mi:MMAA(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_758454.1|refseq:XP_011529986.1|refseq:XP_011529987.1|ensembl:ENSG00000151611(gene)|ensembl:ENST00000541599(transcript)|ensembl:ENST00000648388(transcript)|ensembl:ENST00000649156(transcript)|ensembl:ENST00000649704(transcript)|ensembl:ENST00000679563(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009235"(cobalamin metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR005129(ArgK protein)|interpro:IPR027417|rcsb pdb:2WWW|reactome:R-HSA-196741|reactome:R-HSA-3359475|reactome:R-HSA-3359478|reactome:R-HSA-71032 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:gvb5ET29tQnZOjlK7MgeXg+CL8U9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O14966 - intact:EBI-372165|uniprotkb:B4E1K3|uniprotkb:C9JE77|ensembl:ENSP00000235932|ensembl:ENSP00000356107|ensembl:ENSP00000402910 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rab7l_human(display_long)|uniprotkb:RAB29(gene name)|psi-mi:RAB29(display_short)|uniprotkb:RAB7L1(gene name synonym)|uniprotkb:Rab-7-like protein 1(gene name synonym)|uniprotkb:Ras-related protein Rab-29(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001129134.1|refseq:NP_003920.1|refseq:NP_001129135.1|refseq:NP_001129136.1|refseq:XP_005245626.1|refseq:XP_005245627.1|refseq:XP_005245628.1|refseq:XP_006711668.1|refseq:XP_006711669.1|refseq:XP_016858237.1|refseq:XP_016858238.1|refseq:XP_016858239.1|ensembl:ENSG00000117280(gene)|ensembl:ENST00000235932(transcript)|ensembl:ENST00000367139(transcript)|ensembl:ENST00000414729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0019003"(GDP binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042110"(T cell activation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030697|mint:O14966|rcsb pdb:6HH2|reactome:R-HSA-8873719|dip:DIP-31215N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:iqqWBBmsxTZcMPjfgiBjdv8LzAw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q00059 - intact:EBI-1049924|uniprotkb:Q5U0C6|uniprotkb:B5BU05|uniprotkb:A9QXC6|uniprotkb:A8MRB2|ensembl:ENSP00000420588 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tfam_human(display_long)|uniprotkb:TCF6(gene name synonym)|uniprotkb:Mitochondrial transcription factor 1(gene name synonym)|uniprotkb:Transcription factor 6-like 2(gene name synonym)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short)|uniprotkb:TCF6L2(gene name synonym)|uniprotkb:Transcription factor 6(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003192.1|refseq:NP_001257711.1|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q00059|rcsb pdb:3FGH|rcsb pdb:3TMM|rcsb pdb:3TQ6|rcsb pdb:4NNU|rcsb pdb:4NOD|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:6HB4|rcsb pdb:6HC3|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000108064(gene)|ensembl:ENST00000487519(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031072"(heat shock protein binding) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:JqG4yJbWWsYMvex7a6GDIDxiVcs9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P06744 - intact:EBI-2558394|uniprotkb:Q9UHE6|uniprotkb:Q9BSK5|uniprotkb:Q9BRD3|ensembl:ENSP00000348877|uniprotkb:B4DG39 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:g6pi_human(display_long)|uniprotkb:GPI(gene name)|psi-mi:GPI(display_short)|uniprotkb:Phosphoglucose isomerase(gene name synonym)|uniprotkb:Phosphohexose isomerase(gene name synonym)|uniprotkb:Autocrine motility factor(gene name synonym)|uniprotkb:Neuroleukin(gene name synonym)|uniprotkb:Sperm antigen 36(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000166.2|ensembl:ENSG00000105220(gene)|ensembl:ENST00000356487(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001707"(mesoderm formation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0004347"(glucose-6-phosphate isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007599"(hemostasis)|go:"GO:0007611"(learning or memory)|go:"GO:0008083"(growth factor activity)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0033574"(response to testosterone)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043005"(neuron projection)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043278"(response to morphine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0060170"(ciliary membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001672("Phosphoglucose isomerase (PGI)")|interpro:IPR018189|interpro:IPR023096|interpro:IPR035476|interpro:IPR035482|rcsb pdb:1IAT|rcsb pdb:1IRI|rcsb pdb:1JIQ|rcsb pdb:1JLH|rcsb pdb:1NUH|rcsb pdb:6XUH|rcsb pdb:6XUI|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-5628897|refseq:NP_001171651.1|refseq:NP_001316838.1|refseq:NP_001316839.1|refseq:NP_001316840.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:R3ftNtHikgoVdqLjC4d6I5lpENU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q86XE5 - intact:EBI-9658477|uniprotkb:Q96EV5|uniprotkb:Q5T680|uniprotkb:Q8N9F2|uniprotkb:A8K075|uniprotkb:Q711P0|uniprotkb:Q5T684|ensembl:ENSP00000359680 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hoga1_human(display_long)|uniprotkb:HOGA1(gene name)|psi-mi:HOGA1(display_short)|uniprotkb:C10orf65(gene name synonym)|uniprotkb:DHDPSL(gene name synonym)|uniprotkb:Dihydrodipicolinate synthase-like(gene name synonym)|uniprotkb:Probable 2-keto-4-hydroxyglutarate aldolase(gene name synonym)|uniprotkb:Protein 569272(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001128142.1|refseq:NP_612422.2|ensembl:ENSG00000241935(gene)|ensembl:ENST00000370646(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008700"(4-hydroxy-2-oxoglutarate aldolase activity)|go:"GO:0009436"(glyoxylate catabolic process)|go:"GO:0019470"(4-hydroxyproline catabolic process)|go:"GO:0033609"(oxalate metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042866"(pyruvate biosynthetic process)|go:"GO:0046487"(glyoxylate metabolic process)|interpro:IPR002220(Dihydrodipicolinate synthetase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020625|rcsb pdb:3S5N|rcsb pdb:3S5O|reactome:R-HSA-389661 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:v7mxEtVd8uG+nauFHnLaMqBD+ak9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P31937 - intact:EBI-11427100|uniprotkb:Q546Z2|uniprotkb:Q9UDN3|ensembl:ENSP00000265395 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:3hidh_human(display_long)|uniprotkb:HIBADH(gene name)|psi-mi:HIBADH(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_689953.1|ensembl:ENSG00000106049(gene)|ensembl:ENST00000265395(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006574"(valine catabolic process)|go:"GO:0008442"(3-hydroxyisobutyrate dehydrogenase activity)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|interpro:IPR002204(3-hydroxyisobutyrate dehydrogenase-related, conserved site)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011548(3-hydroxyisobutyrate dehydrogenase)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR015815(3-hydroxyacid dehydrogenase/reductase)|interpro:IPR029154|interpro:IPR036291|rcsb pdb:2GF2|rcsb pdb:2I9P|reactome:R-HSA-70895 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:YDYnI6BHB7iD3J2h+rR4GwFfrtg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P52815 - intact:EBI-358272|uniprotkb:Q969U0|uniprotkb:Q9HCA2|uniprotkb:Q9UQJ3|ensembl:ENSP00000333837 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rm12_human(display_long)|uniprotkb:MRPL12(gene name)|psi-mi:MRPL12(display_short)|uniprotkb:RPML12(gene name synonym)|uniprotkb:5c5-2(gene name synonym)|uniprotkb:MRPL7(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL12m(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002940.2|ensembl:ENSG00000262814(gene)|ensembl:ENST00000333676(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006412"(translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000206(Ribosomal protein L7/L12)|interpro:IPR008932(Ribosomal protein L7/L12, oligomerisation)|interpro:IPR013823(Ribosomal protein L7/L12, C-terminal)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR036235|mint:P52815|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|dip:DIP-50865N|rcsb pdb:6ZSG|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:rs6bdQ5j/8fLRbXZqqS6GgR7AzI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P60866 - intact:EBI-353105|uniprotkb:P17075|uniprotkb:Q5M8S9|uniprotkb:B2R4F4|uniprotkb:B4DW28|ensembl:ENSP00000009589|ensembl:ENSP00000427788|ensembl:ENSP00000503327|ensembl:ENSP00000504123|ensembl:ENSP00000504154|ensembl:ENSP00000504670 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rs20_human(display_long)|uniprotkb:RPS20(gene name)|psi-mi:RPS20(display_short)|uniprotkb:Small ribosomal subunit protein uS10(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001014.1|refseq:NP_001139699.1|dip:DIP-31245N|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|ensembl:ENSG00000008988(gene)|ensembl:ENST00000009589(transcript)|ensembl:ENST00000521262(transcript)|ensembl:ENST00000676461(transcript)|ensembl:ENST00000676918(transcript)|ensembl:ENST00000678039(transcript)|ensembl:ENST00000678683(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001848(Ribosomal protein S10)|interpro:IPR005729(Ribosomal protein S10, eukaryotic/archaeal)|interpro:IPR018268|interpro:IPR027486|interpro:IPR036838|mint:P60866|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:6xNxX+eP59AOm0KraCysRHUqMFw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8N4F0 - intact:EBI-20896337|ensembl:ENSP00000170150|uniprotkb:Q6UWN3|uniprotkb:Q6ZME0|uniprotkb:Q8NFQ7 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:bpib2_human(display_long)|uniprotkb:Bactericidal/permeability-increasing protein-like 1(gene name synonym)|uniprotkb:Long palate, lung and nasal epithelium carcinoma-associated protein 2(gene name synonym)|uniprotkb:RYSR(gene name synonym)|uniprotkb:UNQ2489/PRO5776(orf name)|uniprotkb:BPIFB2(gene name)|psi-mi:BPIFB2(display_short)|uniprotkb:BPIL1(gene name synonym)|uniprotkb:C20orf184(gene name synonym)|uniprotkb:LPLUNC2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000078898(gene)|ensembl:ENST00000170150(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0008289"(lipid binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001124(Lipid-binding serum glycoprotein)|interpro:IPR017942|interpro:IPR017943|interpro:IPR030675|reactome:R-HSA-381426|reactome:R-HSA-6803157|reactome:R-HSA-8957275|refseq:NP_079503.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:JnkHaJ7L2OmXVA+llQXALydZPgI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P11166 - intact:EBI-717153|uniprotkb:A8K9S6|uniprotkb:O75535|uniprotkb:Q147X2|uniprotkb:B2R620|uniprotkb:D3DPX0|uniprotkb:Q0P512|ensembl:ENSP00000416293 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:gtr1_human(display_long)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)|uniprotkb:HepG2 glucose transporter(gene name synonym)|uniprotkb:SLC2A1(gene name)|psi-mi:SLC2A1(display_short)|uniprotkb:GLUT1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_006507.2|ensembl:ENSG00000117394(gene)|ensembl:ENST00000426263(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0072562"(blood microparticle)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11166|rcsb pdb:1SUK|rcsb pdb:4PYP|rcsb pdb:5EQG|rcsb pdb:5EQH|rcsb pdb:5EQI|rcsb pdb:6THA|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-422356|reactome:R-HSA-5619043|reactome:R-HSA-5653890|dip:DIP-23N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:72DLUG1CFkqcf92goIZBZ4+zuls9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P01834 - intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - rcsb pdb:2NY7|rcsb pdb:1N0X|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:4D3C|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5ESV|rcsb pdb:5ESZ|reactome:R-HSA-5690714|rcsb pdb:6OGE|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1UCB|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:5B39|rcsb pdb:5B38|reactome:R-HSA-202733|rcsb pdb:3U0W|rcsb pdb:1DFB|rcsb pdb:3WUW|rcsb pdb:1HZH|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:4D9R|rcsb pdb:4HIX|go:"GO:0001895"(retina homeostasis)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1CLY|rcsb pdb:1GAF|rcsb pdb:2RFX|rcsb pdb:3IU3|rcsb pdb:3RU8|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-983695|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|reactome:R-HSA-977606|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:5VEB|rcsb pdb:5VIY|interpro:IPR036179|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6OKP|reactome:R-HSA-9664323|reactome:R-HSA-9664422 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O43678 - intact:EBI-1246398|uniprotkb:Q6IAY8|uniprotkb:D6RJD6|ensembl:ENSP00000252102 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ndua2_human(display_long)|uniprotkb:NDUFA2(gene name)|psi-mi:NDUFA2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002479.1|refseq:NP_001171941.1|ensembl:ENSG00000131495(gene)|ensembl:ENST00000252102(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|rcsb pdb:1S3A|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:bL66utte1nSuYj0nxg/BoktnXhs9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96A26 - intact:EBI-6123466|uniprotkb:Q9NRN6|uniprotkb:Q9UJX8|ensembl:ENSP00000419088 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:f162a_human(display_long)|uniprotkb:FAM162A(gene name)|psi-mi:FAM162A(display_short)|uniprotkb:C3orf28(gene name synonym)|uniprotkb:E2IG5(gene name synonym)|uniprotkb:E2-induced gene 5 protein(gene name synonym)|uniprotkb:Growth and transformation-dependent protein(gene name synonym)|uniprotkb:DC16(orf name)|uniprotkb:FWP001(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_055182.3|ensembl:ENSG00000114023(gene)|ensembl:ENST00000477892(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|interpro:IPR009432(Protein of unknown function DUF1075)|mint:Q96A26 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:CjOkqa9wFwEOorjQt5oI7/EJ6709606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P02100 - intact:EBI-6190240|ensembl:ENSP00000292896|ensembl:ENSP00000369586|ensembl:ENSP00000380104|uniprotkb:Q6FH44 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hbe_human(display_long)|uniprotkb:HBE1(gene name)|psi-mi:HBE1(display_short)|uniprotkb:HBE(gene name synonym)|uniprotkb:Epsilon-globin(gene name synonym)|uniprotkb:Hemoglobin epsilon chain(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000213931(gene)|ensembl:ENST00000292896(transcript)|ensembl:ENST00000380237(transcript)|ensembl:ENST00000396895(transcript)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1A9W|reactome:R-HSA-983231|refseq:NP_005321.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:ZKgpsS0AFjNRaxSJ4ctde2ESHik9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P52209 - intact:EBI-372761|uniprotkb:Q9BWD8|intact:EBI-11020895|uniprotkb:A8K2Y9|ensembl:ENSP00000270776|uniprotkb:B4DQJ8 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:6pgd_human(display_long)|uniprotkb:PGD(gene name)|psi-mi:PGD(display_short)|uniprotkb:PGDH(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001291380.1|refseq:NP_001291381.1|refseq:NP_002622.2|ensembl:ENSG00000142657(gene)|ensembl:ENST00000270776(transcript)|go:"GO:0004616"("phosphogluconate dehydrogenase (decarboxylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0046177"(D-gluconate catabolic process)|go:"GO:0050661"(NADP binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006113(6-phosphogluconate dehydrogenase, decarboxylating)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|mint:P52209|rcsb pdb:2JKV|rcsb pdb:4GWG|rcsb pdb:4GWK|rcsb pdb:5UQ9|reactome:R-HSA-71336|interpro:IPR036291 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:SgbOgCLmdWm3QnN6fQfkHG6iunw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9P035 - intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q15370 - intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9Y2R0 - intact:EBI-6570446|uniprotkb:A8K498|ensembl:ENSP00000354762 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:coa3_human(display_long)|uniprotkb:COA3(gene name)|psi-mi:COA3(display_short)|uniprotkb:CCDC56(gene name synonym)|uniprotkb:MITRAC12(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 56(gene name synonym)|uniprotkb:Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa(gene name synonym)|uniprotkb:HSPC009(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001035521.1|ensembl:ENSG00000183978(gene)|ensembl:ENST00000328434(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0070131"(positive regulation of mitochondrial translation)|interpro:IPR018628|interpro:IPR041752 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:xDKgvGxvOS7YMkleFm3VAQgfcOU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O95298 - intact:EBI-1246172|uniprotkb:Q9UBJ9|uniprotkb:Q6FIH8|uniprotkb:Q549M5|uniprotkb:E9PNU8|uniprotkb:E9PRB2|ensembl:ENSP00000281031 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:nduc2_human(display_long)|uniprotkb:NDUFC2(gene name)|psi-mi:NDUFC2(display_short)|uniprotkb:HLC1(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5b(gene name synonym)|uniprotkb:Complex I-B14.5b(gene name synonym)|uniprotkb:Human lung cancer oncogene 1 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_004540.1|refseq:NP_001190983.1|refseq:NP_001190984.1|ensembl:ENSG00000151366(gene)|ensembl:ENST00000281031(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005886"(plasma membrane)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR009423(NADH-ubiquinone oxidoreductase subunit b14.5b)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6798695|reactome:R-HSA-6799198 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:IILkKsJHyRjCMZJ6z//WjdRXQUQ9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P35240 - intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96MG8 - intact:EBI-2561395|ensembl:ENSP00000353739|ensembl:ENSP00000428099|uniprotkb:Q96FK9 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pcmd1_human(display_long)|uniprotkb:PCMTD1(gene name)|psi-mi:PCMTD1(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000168300(gene)|ensembl:ENST00000360540(transcript)|ensembl:ENST00000522514(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063|refseq:NP_443169.2|refseq:NP_001273711.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:SgeW0DQ1DOC3HHJHzadt4RIRJs09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P32119 - intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q13423 - intact:EBI-1391318|uniprotkb:Q16796|uniprotkb:Q2TB60|uniprotkb:Q8N3V4|ensembl:ENSP00000264663|ensembl:ENSP00000343873|ensembl:ENSP00000499249|ensembl:ENSP00000499281|ensembl:ENSP00000499494|ensembl:ENSP00000499527|ensembl:ENSP00000499611|ensembl:ENSP00000499639 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:nntm_human(display_long)|uniprotkb:NNT(gene name)|psi-mi:NNT(display_short)|uniprotkb:Nicotinamide nucleotide transhydrogenase(gene name synonym)|uniprotkb:Pyridine nucleotide transhydrogenase(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_036475.3|refseq:NP_892022.2|refseq:XP_011512303.1|refseq:XP_016864782.1|refseq:XP_005248331.1|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903285"(positive regulation of hydrogen peroxide catabolic process)|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR008142(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-1)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|interpro:IPR024605|interpro:IPR026255|interpro:IPR029035|interpro:IPR034300|interpro:IPR036291|mint:Q13423|rcsb pdb:1DJL|rcsb pdb:1PT9|rcsb pdb:1U31|reactome:R-HSA-71403|ensembl:ENSG00000112992(gene)|ensembl:ENST00000264663(transcript)|ensembl:ENST00000344920(transcript)|ensembl:ENST00000653251(transcript)|ensembl:ENST00000656666(transcript)|ensembl:ENST00000662525(transcript)|ensembl:ENST00000669601(transcript)|ensembl:ENST00000670904(transcript)|ensembl:ENST00000671668(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003957"("NAD(P)+ transhydrogenase (B-specific) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006740"(NADPH regeneration)|go:"GO:0008746"("NAD(P)+ transhydrogenase activity")|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0033273"(response to vitamin)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0072593"(reactive oxygen species metabolic process) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:iDKBuEy/JvV9q3s4/aHuu58+Gyk9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NVH6 - intact:EBI-395312|uniprotkb:Q5TZB5|uniprotkb:Q6IA90|uniprotkb:Q8TBT0|ensembl:ENSP00000335261|uniprotkb:A8K6M9|uniprotkb:B4E3R3 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tmlh_human(display_long)|uniprotkb:TMLHE(gene name)|psi-mi:TMLHE(display_short)|uniprotkb:TMLH(gene name synonym)|uniprotkb:Epsilon-trimethyllysine 2-oxoglutarate dioxygenase(gene name synonym)|uniprotkb:TML-alpha-ketoglutarate dioxygenase(gene name synonym)|uniprotkb:TML hydroxylase(gene name synonym)|uniprotkb:Epsilon-trimethyllysine hydroxylase(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001171726.1|refseq:NP_060666.1|go:"GO:0051354"(negative regulation of oxidoreductase activity)|interpro:IPR003819(Taurine catabolism dioxygenase TauD/TfdA)|interpro:IPR010376(Protein of unknown function DUF971)|interpro:IPR012776(Trimethyllysine dioxygenase)|interpro:IPR038492|interpro:IPR042098|reactome:R-HSA-71262|ensembl:ENSG00000185973(gene)|ensembl:ENST00000334398(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0050353"(trimethyllysine dioxygenase activity) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:QJwymZVdaxmMdea5RhA7vcPCla49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P51153 - intact:EBI-1780121|uniprotkb:Q5U0A6|uniprotkb:Q6GPG6|uniprotkb:Q96GU4|uniprotkb:A8K6B5|uniprotkb:D3DV67|ensembl:ENSP00000357564 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rab13_human(display_long)|uniprotkb:RAB13(gene name)|psi-mi:RAB13(display_short)|uniprotkb:GIG4(orf name)|uniprotkb:Cell growth-inhibiting gene 4 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002861.1|refseq:NP_001258967.1|dip:DIP-40268N|ensembl:ENSG00000143545(gene)|ensembl:ENST00000368575(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0044795"(trans-Golgi network to recycling endosome transport)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097368"(establishment of Sertoli cell barrier)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51153|reactome:R-HSA-1445148|reactome:R-HSA-8873719|reactome:R-HSA-8876198 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:XopTW/3AqUPyTi66Nf0HYlkD6Fw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O75390 - intact:EBI-487493|ensembl:ENSP00000342056|uniprotkb:Q71UT9|uniprotkb:Q7KZH0|uniprotkb:Q96FZ8|uniprotkb:Q9BWN8 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cisy_human(display_long)|uniprotkb:CS(gene name)|psi-mi:CS(display_short)|uniprotkb:"Citrate (Si)-synthase"(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0006101"(citrate metabolic process)|refseq:NP_004068.2|ensembl:ENSG00000062485(gene)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000351328(transcript)|rcsb pdb:5UZQ|rcsb pdb:5UZR|reactome:R-HSA-1268020|reactome:R-HSA-71403|go:"GO:0070062"(extracellular exosome)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|rcsb pdb:5UZP go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:XKpnEsGOlGRNIAXMk4tTBH2okzo9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P51970 - intact:EBI-1237250|uniprotkb:B1AM93|uniprotkb:Q9Y6N0|ensembl:ENSP00000362873 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ndua8_human(display_long)|uniprotkb:NDUFA8(gene name)|psi-mi:NDUFA8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 19 kDa subunit(gene name synonym)|uniprotkb:Complex I-19kD(gene name synonym)|uniprotkb:Complex I-PGIV(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_055037.1|ensembl:ENSG00000119421(gene)|ensembl:ENST00000373768(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR010625(CHCH)|interpro:IPR016680("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8")|mint:P51970|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:buGk0RR4rNyaFDdsjenBqzYzlMs9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UHR5 - intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P55735 - intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P22626 - intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P49406 - intact:EBI-1188518|uniprotkb:Q96Q52|uniprotkb:Q53TX9|ensembl:ENSP00000377486|ensembl:ENSP00000387284 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rm19_human(display_long)|uniprotkb:MRPL15(gene name synonym)|uniprotkb:39S ribosomal protein L15, mitochondrial(gene name synonym)|uniprotkb:MRPL19(gene name)|psi-mi:MRPL19(display_short)|uniprotkb:KIAA0104(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL19m(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_055578.2|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7O9M|ensembl:ENSG00000115364(gene)|ensembl:ENST00000393909(transcript)|ensembl:ENST00000409374(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR001857(Ribosomal protein L19)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR038657|mint:P49406|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:4ZCZpq3u9wkdpuNVFpk+bhceaW09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q13162 - intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96DA0 - intact:EBI-953824|ensembl:ENSP00000371715|ensembl:ENSP00000489035|uniprotkb:A6NIY1|uniprotkb:Q6UW28|uniprotkb:B2R4F6 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:zg16b_human(display_long)|uniprotkb:ZG16B(gene name)|psi-mi:ZG16B(display_short)|uniprotkb:UNQ773/PRO1567(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENST00000634500(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001229(Mannose-binding lectin)|interpro:IPR036404|rcsb pdb:3AQG|ensembl:ENSG00000283056(gene)|ensembl:ENST00000382280(transcript)|ensembl:ENSG00000162078(gene)|refseq:NP_660295.2 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:0ymcb/0tSgZXhYQ6xHNIYrx9F3g9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9HB75 - intact:EBI-520427|ensembl:ENSP00000337797|uniprotkb:Q59FD1|uniprotkb:Q59H10|uniprotkb:Q59HC7|uniprotkb:Q7Z4P8|uniprotkb:Q8NC89|uniprotkb:Q8NDL2|uniprotkb:Q96C25|uniprotkb:Q9NRE6 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pidd1_human(display_long)|uniprotkb:PIDD1(gene name)|psi-mi:PIDD1(display_short)|uniprotkb:LRDD(gene name synonym)|uniprotkb:Leucine-rich repeat and death domain-containing protein(gene name synonym)|uniprotkb:PIDD(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_665893.2|refseq:NP_665894.2|ensembl:ENSG00000177595(gene)|ensembl:ENST00000347755(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:XP_011518512.1|refseq:XP_011518513.1|refseq:XP_016873482.1|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR011029(DEATH-like)|interpro:IPR019502|interpro:IPR032675|mint:Q9HB75|rcsb pdb:2OF5|reactome:R-HSA-6803207 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:n0LSBUZQ057RjeGw0h+yCoXgi0w9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96DR5 - intact:EBI-10284754|uniprotkb:Q9BQQ0|ensembl:ENSP00000253362|ensembl:ENSP00000347012 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:bpia2_human(display_long)|uniprotkb:BPIFA2(gene name)|psi-mi:BPIFA2(display_short)|uniprotkb:C20orf70(gene name synonym)|uniprotkb:Parotid secretory protein(gene name synonym)|uniprotkb:SPLUNC2(gene name synonym)|uniprotkb:Short palate, lung and nasal epithelium carcinoma-associated protein 2(gene name synonym)|uniprotkb:UNQ510/PRO1025(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_542141.1|ensembl:ENSG00000131050(gene)|ensembl:ENST00000253362(transcript)|ensembl:ENST00000354932(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0030141"(secretory granule)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0070062"(extracellular exosome)|interpro:IPR017942|interpro:IPR017943|reactome:R-HSA-6803157|refseq:NP_001306093.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:hUaoERR8Rj8vTTUtNJ0BDlQ5b249606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P42765 - intact:EBI-2852639|uniprotkb:Q9BUT6|ensembl:ENSP00000285093 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:thim_human(display_long)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:ACAA2(gene name)|psi-mi:ACAA2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:T1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_006102.2|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P42765|rcsb pdb:4C2J|rcsb pdb:4C2K|reactome:R-HSA-77289|interpro:IPR020613|ensembl:ENSG00000167315(gene)|ensembl:ENST00000285093(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:TJMFLcEB5eKz36plSuUiteAJN9g9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P14854 - intact:EBI-1047480|uniprotkb:Q6IBL4|uniprotkb:B2R5C9|ensembl:ENSP00000376037|ensembl:ENSP00000466818|ensembl:ENSP00000497926 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cx6b1_human(display_long)|uniprotkb:COX6B1(gene name)|psi-mi:COX6B1(display_short)|uniprotkb:COX6B(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit VIb isoform 1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001854.1|ensembl:ENSG00000126267(gene)|ensembl:ENST00000392201(transcript)|ensembl:ENST00000592141(transcript)|ensembl:ENST00000649813(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0021762"(substantia nigra development)|go:"GO:0045277"(respiratory chain complex IV)|interpro:IPR003213(Cytochrome c oxidase, subunit VIb)|interpro:IPR036549|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:YuBPGRO9+EC9fWz+mWALa2DyZL89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q8NBX0 - intact:EBI-4289902|uniprotkb:Q9Y363|uniprotkb:Q8TAR0|ensembl:ENSP00000355467 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:scpdl_human(display_long)|uniprotkb:SCCPDH(gene name)|psi-mi:SCCPDH(display_short)|uniprotkb:CGI-49(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000143653(gene)|ensembl:ENST00000366510(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030496"(midbody)|go:"GO:0031093"(platelet alpha granule lumen)|interpro:IPR005097(Saccharopine dehydrogenase)|interpro:IPR032095|interpro:IPR036291|reactome:R-HSA-114608|refseq:NP_057086.2 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:3dd8OvU7odCDI/f4Ouk7CJYoxnI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O94988 - intact:EBI-10962518|ensembl:ENSP00000264344|uniprotkb:Q8NBA3|uniprotkb:Q24JP0|uniprotkb:Q5PR21|uniprotkb:B4DLC1 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:fa13a_human(display_long)|uniprotkb:FAM13A(gene name)|psi-mi:FAM13A(display_short)|uniprotkb:FAM13A1(gene name synonym)|uniprotkb:KIAA0914(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001015045.1|refseq:NP_001252507.1|refseq:NP_001252508.1|refseq:NP_001252509.1|refseq:NP_055698.2|refseq:XP_011529818.1|ensembl:ENSG00000138640(gene)|ensembl:ENST00000264344(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039102|mint:O94988|reactome:R-HSA-8980692|reactome:R-HSA-9013149 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Uwm2VF+xwj4Rc5+KKfgBh7l/M6I9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O00468 - intact:EBI-947482|uniprotkb:Q5SVA2|uniprotkb:Q60FE1|uniprotkb:Q7KYS8|uniprotkb:Q8N4J5|uniprotkb:Q96IC1|uniprotkb:Q9BTD4|uniprotkb:Q5SVA1 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:agrin_human(display_long)|uniprotkb:AGRN(gene name)|psi-mi:AGRN(display_short)|uniprotkb:AGRIN(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_940978.2|interpro:IPR004850(Agrin NtA)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR000082(SEA)|interpro:IPR008993(TIMP-like, OB-fold)|refseq:XP_005244806.1|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003884(Factor I membrane attack complex)|mint:O00468|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043236"(laminin binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050808"(synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-216083|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-419037|reactome:R-HSA-4420332|reactome:R-HSA-975634|interpro:IPR036058|interpro:IPR036364|refseq:NP_001292204.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:LRk4v4aYLk5kep9EIbjjiCGM7OM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O95168 - intact:EBI-1245485|uniprotkb:B2RUY3|uniprotkb:B9EJC7|ensembl:ENSP00000184266 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ndub4_human(display_long)|uniprotkb:NDUFB4(gene name)|psi-mi:NDUFB4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001161803.1|refseq:NP_004538.2|ensembl:ENSG00000065518(gene)|ensembl:ENST00000184266(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:O7vikmRDGTcfvmDXSThJKj2ADJc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P21953 - intact:EBI-1029067|uniprotkb:Q5T2J3|ensembl:ENSP00000318351|ensembl:ENSP00000348880|uniprotkb:Q9BQL0 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:odbb_human(display_long)|uniprotkb:BCKDHB(gene name)|psi-mi:BCKDHB(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component beta chain(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000047.1|refseq:NP_898871.1|ensembl:ENST00000356489(transcript)|go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0007584"(response to nutrient)|go:"GO:0009083"(branched-chain amino acid catabolic process)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR029061|interpro:IPR033248|rcsb pdb:1DTW|rcsb pdb:1OLS|rcsb pdb:1OLU|rcsb pdb:1OLX|rcsb pdb:1U5B|rcsb pdb:1V11|rcsb pdb:1V16|rcsb pdb:1V1M|rcsb pdb:1V1R|rcsb pdb:1WCI|rcsb pdb:1X7W|rcsb pdb:1X7X|rcsb pdb:1X7Y|rcsb pdb:1X7Z|rcsb pdb:1X80|rcsb pdb:2BEU|rcsb pdb:2BEV|rcsb pdb:2BEW|rcsb pdb:2BFB|rcsb pdb:2BFC|rcsb pdb:2BFD|rcsb pdb:2BFE|rcsb pdb:2BFF|rcsb pdb:2J9F|reactome:R-HSA-389661|reactome:R-HSA-70895|ensembl:ENSG00000083123(gene)|ensembl:ENST00000320393(transcript)|refseq:NP_001305904.1|dip:DIP-6147N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:2KgCDcF9/M5ZI8/2WV4bU1Qmnvk9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O00217 - intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UIF8 - intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9Y4W6 - intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000141385(gene)|ensembl:ENST00000269143(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|refseq:NP_006787.2|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q92696 - intact:EBI-9104196|uniprotkb:A8K5N2|uniprotkb:D3DS69|ensembl:ENSP00000216840|ensembl:ENSP00000382341|ensembl:ENSP00000494636|ensembl:ENSP00000496595 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pgta_human(display_long)|uniprotkb:RABGGTA(gene name)|psi-mi:RABGGTA(display_short)|uniprotkb:Geranylgeranyl transferase type II subunit alpha(gene name synonym)|uniprotkb:Rab geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:Rab geranylgeranyltransferase subunit alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_004572.3|refseq:NP_878256.1|ensembl:ENSG00000100949(gene)|ensembl:ENSG00000285193(gene)|ensembl:ENST00000216840(transcript)|ensembl:ENST00000399409(transcript)|ensembl:ENST00000644383(transcript)|ensembl:ENST00000646658(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|interpro:IPR009087(Rab geranylgeranyltransferase, alpha subunit, insert)|interpro:IPR032675|interpro:IPR032955|interpro:IPR036254|reactome:R-HSA-6803205|reactome:R-HSA-8873719 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:oPWV+8Ppm2LhrEekspnRE/9YSK09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O75367 - intact:EBI-2868511|uniprotkb:Q7Z5E3|uniprotkb:Q9UP96|uniprotkb:Q9H8P3|uniprotkb:Q503A8|uniprotkb:O75377|uniprotkb:Q96D41|ensembl:ENSP00000423563|ensembl:ENSP00000424971 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:h2ay_human(display_long)|uniprotkb:MACROH2A1(gene name)|psi-mi:MACROH2A1(display_short)|uniprotkb:H2AFY(gene name synonym)|uniprotkb:Histone H2A.y(gene name synonym)|uniprotkb:Medulloblastoma antigen MU-MB-50.205(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:XP_011542031.1|refseq:XP_011542032.1|refseq:NP_001035248.1|refseq:NP_004884.1|refseq:NP_613075.1|refseq:NP_613258.2|dip:DIP-44283N|ensembl:ENSG00000113648(gene)|ensembl:ENST00000510038(transcript)|ensembl:ENST00000511689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0007549"(dosage compensation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|go:"GO:1902882"(regulation of response to oxidative stress)|go:"GO:1902883"(negative regulation of response to oxidative stress)|go:"GO:1902884"(positive regulation of response to oxidative stress)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|go:"GO:1904815"(negative regulation of protein localization to chromosome, telomeric region)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|interpro:IPR032454|interpro:IPR035796|interpro:IPR043472|mint:O75367|rcsb pdb:1U35|rcsb pdb:1ZR3|rcsb pdb:1ZR5|rcsb pdb:2F8N|rcsb pdb:2FXK|rcsb pdb:3HQH|rcsb pdb:3HSV|rcsb pdb:3IID|rcsb pdb:3IIF|rcsb pdb:3IVB|rcsb pdb:5IIT|rcsb pdb:5LNC|interpro:IPR002119(Histone H2A) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:0FCoM0/4mTtnc7cPDUleKuZ3HgM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P35580 - intact:EBI-351758|intact:EBI-7850240|intact:MINT-8330016|uniprotkb:B2RWP9|uniprotkb:D3DTS1|uniprotkb:Q9BWG0|uniprotkb:Q12989|uniprotkb:Q16087|uniprotkb:Q149N3|ensembl:ENSP00000269243|uniprotkb:Q149N4|uniprotkb:Q6PK16|uniprotkb:F8VTL3|uniprotkb:Q4LE45 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:myh10_human(display_long)|uniprotkb:MYH10(gene name)|psi-mi:MYH10(display_short)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001243024.1|refseq:NP_001242941.1|refseq:NP_005955.3|ensembl:ENSG00000133026(gene)|ensembl:ENST00000269243(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042641"(actomyosin)|go:"GO:0043531"(ADP binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097513"(myosin II filament)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35580|rcsb pdb:4PD3|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016880169.1|refseq:XP_016880170.1|refseq:XP_016880171.1|dip:DIP-31110N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:iSHfJZbrWg1L+vSpu1n7RmTTNN49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O60669 - intact:EBI-3921243|ensembl:ENSP00000261187|ensembl:ENSP00000448071|ensembl:ENSP00000448742|ensembl:ENSP00000449547|uniprotkb:Q9UPB3|uniprotkb:Q8NEM3 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:mot2_human(display_long)|uniprotkb:SLC16A7(gene name)|psi-mi:SLC16A7(display_short)|uniprotkb:MCT2(gene name synonym)|uniprotkb:Solute carrier family 16 member 7(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000118596(gene)|ensembl:ENST00000261187(transcript)|ensembl:ENST00000547379(transcript)|ensembl:ENST00000552024(transcript)|ensembl:ENST00000552432(transcript)|go:"GO:0005477"(pyruvate secondary active transmembrane transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035873"(lactate transmembrane transport)|go:"GO:0050833"(pyruvate transmembrane transporter activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901475"(pyruvate transmembrane transport)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR027178|interpro:IPR036259|rcsb pdb:7BP3|reactome:R-HSA-433692|refseq:NP_004722.2|refseq:XP_005269288.1|refseq:NP_001257551.1|refseq:NP_001257552.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:7GastWiFX3mAx0KwXlja44SsSPA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9Y676 - intact:EBI-750085|uniprotkb:Q9BS27|uniprotkb:A6NDQ0|uniprotkb:Q659G4|intact:EBI-1050511|ensembl:ENSP00000259873|ensembl:ENSP00000383438|ensembl:ENSP00000397790|ensembl:ENSP00000398494|ensembl:ENSP00000402718|ensembl:ENSP00000414972|ensembl:ENSP00000415703 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rt18b_human(display_long)|uniprotkb:28S ribosomal protein S18-2, mitochondrial(gene name synonym)|uniprotkb:C6orf14(gene name synonym)|uniprotkb:MRPS18B(gene name)|psi-mi:MRPS18B(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein bS18b(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS40(gene name synonym)|uniprotkb:HSPC183(orf name)|uniprotkb:PTD017(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_054765.1|dip:DIP-29894N|ensembl:ENSG00000203624(gene)|ensembl:ENSG00000204568(gene)|ensembl:ENSG00000223775(gene)|ensembl:ENSG00000226111(gene)|ensembl:ENSG00000227420(gene)|ensembl:ENSG00000229861(gene)|ensembl:ENSG00000233813(gene)|ensembl:ENST00000259873(transcript)|ensembl:ENST00000327800(transcript)|ensembl:ENST00000412451(transcript)|ensembl:ENST00000426945(transcript)|ensembl:ENST00000430402(transcript)|ensembl:ENST00000451032(transcript)|ensembl:ENST00000454427(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0030054"(cell junction)|go:"GO:0032543"(mitochondrial translation)|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|interpro:IPR001648(Ribosomal protein S18)|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|interpro:IPR036870|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|interpro:IPR040054|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|mint:Q9Y676 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:DFGekxKm74bAo8IWpOi8LDITWqc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P29401 - intact:EBI-1050560|uniprotkb:Q8TBA3|uniprotkb:Q96HH3|uniprotkb:A8K089|uniprotkb:B4DE31|uniprotkb:E7EPA7|ensembl:ENSP00000405455|ensembl:ENSP00000417773|intact:EBI-11110174 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tkt_human(display_long)|uniprotkb:TKT(gene name)|psi-mi:TKT(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001055.1|refseq:NP_001128527.1|refseq:NP_001244957.1|ensembl:ENSG00000163931(gene)|ensembl:ENST00000423525(transcript)|ensembl:ENST00000462138(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004802"(transketolase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0016604"(nuclear body)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031982"(vesicle)|go:"GO:0040008"(regulation of growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|mint:P29401|rcsb pdb:3MOS|rcsb pdb:3OOY|rcsb pdb:4KXU|rcsb pdb:4KXV|rcsb pdb:4KXW|rcsb pdb:4KXX|rcsb pdb:4KXY|rcsb pdb:6HA3|rcsb pdb:6HAD|rcsb pdb:6RJB|reactome:R-HSA-163754|reactome:R-HSA-71336|refseq:XP_011532356.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Z3Ad5GdEd0rFCT9uHv85N+2KAAY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O76062 - intact:EBI-2115348|uniprotkb:O95982|uniprotkb:Q8IY06|uniprotkb:Q96E64|uniprotkb:Q96GZ1|uniprotkb:A8K4H0|ensembl:ENSP00000279263 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:erg24_human(display_long)|uniprotkb:TM7SF2(gene name)|psi-mi:TM7SF2(display_short)|uniprotkb:ANG1(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym)|uniprotkb:Transmembrane 7 superfamily member 2(gene name synonym)|uniprotkb:Another new gene 1 protein(gene name synonym)|uniprotkb:Putative sterol reductase SR-1(gene name synonym)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003264.2|refseq:NP_001264162.1|ensembl:ENSG00000149809(gene)|ensembl:ENST00000279263(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0050661"(NADP binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR018083|mint:O76062|reactome:R-HSA-191273|reactome:R-HSA-2426168 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:jLbMB63WqPnGYB7Q3zzTd76G/sg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96RL7 - intact:EBI-1752583|uniprotkb:Q5JSX9|uniprotkb:Q5JSY0|uniprotkb:Q5VYR5|uniprotkb:Q702P4|uniprotkb:Q709D0|uniprotkb:Q86YF8|uniprotkb:Q96S61|uniprotkb:Q9H995|uniprotkb:Q9Y2J1|ensembl:ENSP00000353422 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:vp13a_human(display_long)|uniprotkb:VPS13A(gene name)|psi-mi:VPS13A(display_short)|uniprotkb:CHAC(gene name synonym)|uniprotkb:KIAA0986(gene name synonym)|uniprotkb:Chorein(gene name synonym)|uniprotkb:Chorea-acanthocytosis protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001018047.1|refseq:NP_001018048.1|refseq:NP_056001.1|refseq:NP_150648.2|ensembl:ENSG00000197969(gene)|ensembl:ENST00000360280(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006914"(autophagy)|go:"GO:0007399"(nervous system development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035176"(social behavior)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0097225"(sperm midpiece)|go:"GO:0099013"(neuronal dense core vesicle lumen)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR009543(Vacuolar protein sorting-associated protein)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026847|interpro:IPR026854|interpro:IPR031642|interpro:IPR031645|interpro:IPR031646 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:GKpJsczlbPL6VtrpaPXX8K5D0xY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NZ01 - intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P31040 - intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9BZE1 - intact:EBI-5325218|ensembl:ENSP00000354086|uniprotkb:Q96Q67|uniprotkb:Q9BWR1|uniprotkb:Q9P0P3 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rm37_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL37(gene name synonym)|uniprotkb:MRPL37(gene name)|psi-mi:MRPL37(display_short)|uniprotkb:MRPL2(gene name synonym)|uniprotkb:RPML2(gene name synonym)|uniprotkb:39S ribosomal protein L2, mitochondrial(gene name synonym)|uniprotkb:HSPC235(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000116221(gene)|ensembl:ENST00000360840(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR010793(Ribosomal protein S30, mitochondrial)|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:3J7Y|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:3J9M|rcsb pdb:7ODR|rcsb pdb:5OOL|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:5OOM|rcsb pdb:7OF0|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OG4|refseq:NP_057575.2|dip:DIP-59718N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:rYwNelB9BJA4STHaD5AlJjUxCpM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q02218 - intact:EBI-747213|intact:EBI-1210683|uniprotkb:Q9UDX0|uniprotkb:D3DVL0|uniprotkb:B4E2U9|uniprotkb:E9PBM1|uniprotkb:Q96DD3|ensembl:ENSP00000222673 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:odo1_human(display_long)|uniprotkb:OGDH(gene name)|psi-mi:OGDH(display_short)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002532.2|refseq:NP_001003941.1|refseq:NP_001158508.1|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0021756"(striatum development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034602"("oxoglutarate dehydrogenase (NAD+) activity")|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0106077"(histone succinylation)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|rcsb pdb:3ERY|reactome:R-HSA-389661|reactome:R-HSA-71064|reactome:R-HSA-71403|ensembl:ENSG00000105953(gene)|ensembl:ENST00000222673(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0021695"(cerebellar cortex development)|dip:DIP-39353N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:B9CSRCmhDYg7n5jSpuDlr2mrxDg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P61313 - intact:EBI-443462|ensembl:ENSP00000309334|ensembl:ENSP00000346867|ensembl:ENSP00000388529|ensembl:ENSP00000416692|ensembl:ENSP00000483260|ensembl:ENSP00000493759|uniprotkb:Q642I1|uniprotkb:Q9H2E5|uniprotkb:P39030|uniprotkb:P41051|uniprotkb:Q6IPX6|uniprotkb:Q8WYP2|uniprotkb:Q96C44|uniprotkb:Q5U0C0|intact:EBI-2877712 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rl15_human(display_long)|uniprotkb:RPL15(gene name)|psi-mi:RPL15(display_short)|uniprotkb:EC45(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL15(gene name synonym)|uniprotkb:TCBAP0781(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000174748(gene)|ensembl:ENST00000307839(transcript)|ensembl:ENST00000354811(transcript)|ensembl:ENST00000413699(transcript)|ensembl:ENST00000415719(transcript)|ensembl:ENST00000611050(transcript)|ensembl:ENST00000644185(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:P61313|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002939.2|refseq:NP_001240308.1|refseq:NP_001240309.1|refseq:NP_001240311.1|refseq:NP_001240312.1|refseq:NP_001240313.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:wllGpJicgC5uwkZV6e4QRwDcrBo9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P08865 - intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O14979 - intact:EBI-299727|ensembl:ENSP00000295470|ensembl:ENSP00000422040|ensembl:ENSP00000483254|uniprotkb:Q6SPF2|uniprotkb:Q7KZ74|uniprotkb:Q7KZ75|uniprotkb:Q96IM0|uniprotkb:Q96S43 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hnrdl_human(display_long)|uniprotkb:HNRNPDL(gene name)|psi-mi:HNRNPDL(display_short)|uniprotkb:AU-rich element RNA-binding factor(gene name synonym)|uniprotkb:HNRPDL(gene name synonym)|uniprotkb:JKT41-binding protein(gene name synonym)|uniprotkb:JKTBP(gene name synonym)|uniprotkb:Protein laAUF1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000152795(gene)|ensembl:ENST00000295470(transcript)|ensembl:ENST00000502762(transcript)|ensembl:ENST00000621267(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034847|interpro:IPR035979|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|mint:O14979|go:"GO:0003723"(RNA binding)|reactome:R-HSA-8950505|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034046"("poly(G) binding")|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001193929.1|refseq:NP_112740.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:oOnEEar8AtKO5G6ldehucaRr4kM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O95299 - intact:EBI-1246361|uniprotkb:Q8WXC9|ensembl:ENSP00000252711|ensembl:ENSP00000503956|ensembl:ENSP00000504765 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:nduaa_human(display_long)|uniprotkb:NDUFA10(gene name)|psi-mi:NDUFA10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 42 kDa subunit(gene name synonym)|uniprotkb:Complex I-42kD(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_004535.1|ensembl:ENSG00000130414(gene)|ensembl:ENST00000252711(transcript)|ensembl:ENST00000676929(transcript)|ensembl:ENST00000678158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR015828(NADH-ubiquinone oxidoreductase, 42 kDa subunit)|interpro:IPR027417|interpro:IPR031314|mint:O95299|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:8jwJPJ0rD9H7A4AzxPd186tpXYs9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P05023 - intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q1KMD3 - intact:EBI-1059150|uniprotkb:Q8N3B3|ensembl:ENSP00000301785 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hnrl2_human(display_long)|uniprotkb:HNRNPUL2(gene name)|psi-mi:HNRNPUL2(display_short)|uniprotkb:HNRPUL2(gene name synonym)|uniprotkb:Scaffold-attachment factor A2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001073027.1|ensembl:ENSG00000214753(gene)|ensembl:ENST00000301785(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q1KMD3 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:TOoq1VTfNNzysqSyPH9MHLbSKPA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q99729 - intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P82921 - intact:EBI-2372155|uniprotkb:Q9BST6|uniprotkb:A0A075B746|uniprotkb:Q5TB11|ensembl:ENSP00000461930|ensembl:ENSP00000480129 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rt21_human(display_long)|uniprotkb:MRPS21(gene name)|psi-mi:MRPS21(display_short)|uniprotkb:RPMS21(gene name synonym)|uniprotkb:MDS016(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein bS21m(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_061870.1|refseq:NP_114107.1|ensembl:ENSG00000266472(gene)|ensembl:ENST00000581066(transcript)|ensembl:ENST00000614145(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001911(Ribosomal protein S21)|interpro:IPR038380|mint:P82921|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:AGyHmum6PLo+BxY+wgQvG2894A49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q15293 - intact:EBI-948278|ensembl:ENSP00000054950|uniprotkb:D3DR00|uniprotkb:B7Z1M1 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rcn1_human(display_long)|uniprotkb:RCN1(gene name)|psi-mi:RCN1(display_short)|uniprotkb:RCN(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - reactome:R-HSA-8957275|reactome:R-HSA-381426|ensembl:ENSG00000049449(gene)|ensembl:ENST00000054950(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q15293|refseq:NP_002892.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:ynhvrXX2fQ7Dn1LT+mp2PKm0bc89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P14406 - intact:EBI-2606666|uniprotkb:Q5TF59|uniprotkb:Q6FGI2|uniprotkb:Q3MIH5|uniprotkb:B2R5E1|ensembl:ENSP00000506727 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cx7a2_human(display_long)|uniprotkb:COX7AL(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit VIIa-liver/heart(gene name synonym)|uniprotkb:COX7A2(gene name)|psi-mi:COX7A2(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001856.2|ensembl:ENSG00000112695(gene)|ensembl:ENST00000684430(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR003177(Cytochrome c oxidase, subunit VIIa)|interpro:IPR036539|interpro:IPR039297|mint:P14406|rcsb pdb:5Z62 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:krjTK658npBV4G6gH28GJhVqBkY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P01877 - intact:EBI-1044357|ensembl:ENSP00000374981|uniprotkb:A0A075B6N7 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:igha2_human(display_long)|uniprotkb:IGHA2(gene name)|psi-mi:IGHA2(display_short)|uniprotkb:Ig alpha-2 chain C region(gene name synonym)|uniprotkb:Ig alpha-2 chain C region BUT(gene name synonym)|uniprotkb:Ig alpha-2 chain C region LAN(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000211890(gene)|ensembl:ENST00000390539(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071748"(monomeric IgA immunoglobulin complex)|go:"GO:0071751"(secretory IgA immunoglobulin complex)|go:"GO:0071752"(secretory dimeric IgA immunoglobulin complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:3CM9|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|reactome:R-HSA-202733|reactome:R-HSA-2168880|go:"GO:0042571"(immunoglobulin complex, circulating) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:16SA5N+c5JgKZeFkGst2btxsSWE9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q09028 - intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P07900 - intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P30838 - intact:EBI-3905126|uniprotkb:Q9BT37|uniprotkb:A8K828|ensembl:ENSP00000225740|ensembl:ENSP00000388469|ensembl:ENSP00000411821 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:al3a1_human(display_long)|uniprotkb:ALDH3A1(gene name)|psi-mi:ALDH3A1(display_short)|uniprotkb:ALDH3(gene name synonym)|uniprotkb:ALDHIII(gene name synonym)|uniprotkb:Aldehyde dehydrogenase 3(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 3 member A1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000682.3|refseq:NP_001128639.1|refseq:NP_001128640.1|ensembl:ENSG00000108602(gene)|ensembl:ENST00000225740(transcript)|ensembl:ENST00000444455(transcript)|ensembl:ENST00000457500(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018479"("benzaldehyde dehydrogenase (NAD+) activity")|go:"GO:0042493"|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|rcsb pdb:3SZA|rcsb pdb:3SZB|rcsb pdb:4H80|rcsb pdb:4L1O|rcsb pdb:4L2O|reactome:R-HSA-211945 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:bpEh9WjDg9iuy1HpIXGzf8idWsI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UBX3 - intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0071422"(succinate transmembrane transport)|ensembl:ENSG00000183048(gene)|ensembl:ENST00000350690(transcript)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006811"(ion transport)|go:"GO:0006835"(dicarboxylic acid transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|reactome:R-HSA-70263|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P67812 - intact:EBI-1042500|uniprotkb:O75957|uniprotkb:P21378|uniprotkb:B4DUL4|uniprotkb:H0YK72|uniprotkb:H0YK83|uniprotkb:Q53FQ8|uniprotkb:B2RAD7|ensembl:ENSP00000268220 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sc11a_human(display_long)|uniprotkb:SEC11A(gene name)|psi-mi:SEC11A(display_short)|uniprotkb:SPC18(gene name synonym)|uniprotkb:SPCS4A(gene name synonym)|uniprotkb:SEC11 homolog A(gene name synonym)|uniprotkb:SEC11-like protein 1(gene name synonym)|uniprotkb:Microsomal signal peptidase 18 kDa subunit(gene name synonym)|uniprotkb:Endopeptidase SP18(gene name synonym)|uniprotkb:SEC11L1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_055115.1|ensembl:ENSG00000140612(gene)|ensembl:ENST00000268220(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001733(Peptidase S26B, eukaryotic signal peptidase)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|interpro:IPR019533|interpro:IPR019756|interpro:IPR019758|interpro:IPR036286|interpro:IPR037712|mint:P67812|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|go:"GO:0005787"(signal peptidase complex)|refseq:NP_001258847.1|refseq:NP_001258848.1|refseq:NP_001258849.1|refseq:NP_001258850.1|refseq:NP_001258851.1|dip:DIP-50359N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:zaXzKdryO7BUa6mNJF2DsvIxIJU9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q14165 - intact:EBI-1046466|ensembl:ENSP00000228506 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:mlec_human(display_long)|uniprotkb:MLEC(gene name)|psi-mi:MLEC(display_short)|uniprotkb:KIAA0152(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000110917(gene)|ensembl:ENST00000228506(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0035579"(specific granule membrane)|interpro:IPR021720|interpro:IPR039155|rcsb pdb:6S7T|reactome:R-HSA-532668|reactome:R-HSA-6798695|refseq:NP_055545.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:bEjayZ3by/oF+uvxqdw2r69ab2k9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P10606 - intact:EBI-1053725|uniprotkb:Q96J18|uniprotkb:Q99610|uniprotkb:Q53YB7|ensembl:ENSP00000258424 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:cox5b_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Vb(gene name synonym)|uniprotkb:COX5B(gene name)|psi-mi:COX5B(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001853.2|ensembl:ENSG00000135940(gene)|ensembl:ENST00000258424(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0046872"(metal ion binding)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|interpro:IPR036972|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:EG8kMS2jKMWzQQokTXS2bYk4fHc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P01833 - intact:EBI-1052371|uniprotkb:Q68D81|uniprotkb:Q8IZY7|ensembl:ENSP00000348888 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pigr_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated protein TB6(gene name synonym)|uniprotkb:PIGR(gene name)|psi-mi:PIGR(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002635.2|refseq:XP_011507931.1|ensembl:ENSG00000162896(gene)|ensembl:ENST00000356495(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001792"(polymeric immunoglobulin receptor activity)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002415"(immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0038093"(Fc receptor signaling pathway)|go:"GO:0043113"(receptor clustering)|go:"GO:0043235"(receptor complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071751"(secretory IgA immunoglobulin complex)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1XED|rcsb pdb:2OCW|rcsb pdb:3CHN|rcsb pdb:3CM9|rcsb pdb:5D4K|rcsb pdb:6KXS|rcsb pdb:6LX3|rcsb pdb:6LXW|rcsb pdb:6UE7|rcsb pdb:6UE8|rcsb pdb:6UE9|rcsb pdb:6UEA|rcsb pdb:7K0C|reactome:R-HSA-6798695 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:qidY3KoxSMLEzEryHDcr9OZoXo49606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q5SW79 - intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500|ensembl:ENSP00000483344 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702(gene)|ensembl:ENSG00000276725(gene)|ensembl:ENST00000366542(transcript)|ensembl:ENST00000612450(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P43353 - intact:EBI-2558314|uniprotkb:Q8N515|uniprotkb:Q53XL5|uniprotkb:Q96CK8|ensembl:ENSP00000473990|ensembl:ENSP00000478486|uniprotkb:A3FMP9 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:al3b1_human(display_long)|uniprotkb:ALDH3B1(gene name)|psi-mi:ALDH3B1(display_short)|uniprotkb:ALDH7(gene name synonym)|uniprotkb:Aldehyde dehydrogenase 7(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000685.1|refseq:NP_001025181.1|refseq:NP_001154945.1|ensembl:ENSG00000006534(gene)|ensembl:ENST00000342456(transcript)|ensembl:ENST00000614849(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0018477"("benzaldehyde dehydrogenase (NADP+) activity")|go:"GO:0018479"("benzaldehyde dehydrogenase (NAD+) activity")|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035579"(specific granule membrane)|go:"GO:0046185"(aldehyde catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P43353|reactome:R-HSA-1660661|reactome:R-HSA-6798695|refseq:NP_001276987.1|refseq:NP_001276988.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:mvhm20M4f1djLjELm/uH3AfNPq89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P28370 - intact:EBI-2822460|uniprotkb:Q5JV41|uniprotkb:Q5JV42|ensembl:ENSP00000360163 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:smca1_human(display_long)|uniprotkb:SMARCA1(gene name)|psi-mi:SMARCA1(display_short)|uniprotkb:SNF2L(gene name synonym)|uniprotkb:SNF2L1(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA1(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit SNF2L(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003060.2|refseq:NP_001269804.1|refseq:XP_006724845.1|refseq:XP_016885239.1|refseq:XP_005262518.1|dip:DIP-57685N|ensembl:ENSG00000102038(gene)|ensembl:ENST00000371122(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0090537"(CERF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044755|mint:P28370 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:BBDJMLUdqadz6iXLKjLJto+XF5s9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P52895 - intact:EBI-5658927|ensembl:ENSP00000370129|uniprotkb:B4DKR9|uniprotkb:Q5SR16|uniprotkb:Q96A71|uniprotkb:Q7M4N1|uniprotkb:A8K2N9|uniprotkb:Q14133 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ak1c2_human(display_long)|uniprotkb:3-alpha-HSD3(gene name synonym)|uniprotkb:Chlordecone reductase homolog HAKRD(gene name synonym)|uniprotkb:DDH2(gene name synonym)|uniprotkb:Dihydrodiol dehydrogenase 2(gene name synonym)|uniprotkb:Dihydrodiol dehydrogenase/bile acid-binding protein(gene name synonym)|uniprotkb:Type III 3-alpha-hydroxysteroid dehydrogenase(gene name synonym)|uniprotkb:AKR1C2(gene name)|psi-mi:AKR1C2(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000151632(gene)|ensembl:ENST00000380753(transcript)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005829"(cytosol)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007586"(digestion)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016229"(steroid dehydrogenase activity)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0018636"(phenanthrene 9,10-monooxygenase activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032052"(bile acid binding)|go:"GO:0042448"(progesterone metabolic process)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0047023"(androsterone dehydrogenase activity)|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0047086"(ketosteroid monooxygenase activity)|go:"GO:0047115"(trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity)|go:"GO:0047718"(indanol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071395"(cellular response to jasmonic acid stimulus)|go:"GO:0071799"(cellular response to prostaglandin D stimulus)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|interpro:IPR044482|rcsb pdb:1IHI|rcsb pdb:1J96|rcsb pdb:1XJB|rcsb pdb:2HDJ|rcsb pdb:2IPJ|rcsb pdb:4JQ1|rcsb pdb:4JQ2|refseq:NP_001345.1|refseq:NP_995317.1|refseq:NP_001128713.1|rcsb pdb:4JQ3|rcsb pdb:4JQ4|rcsb pdb:4JQA|rcsb pdb:4JTQ|rcsb pdb:4JTR|rcsb pdb:4L1W|rcsb pdb:4L1X|rcsb pdb:4XO6|rcsb pdb:4XO7|reactome:R-HSA-193368|reactome:R-HSA-193775|reactome:R-HSA-193807 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:1Ebp59003LAdRmDRBKh3QaSkAUs9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O95817 - intact:EBI-747185|uniprotkb:Q3B763|uniprotkb:Q9NT20|uniprotkb:Q9P120|uniprotkb:A8K5L8|ensembl:ENSP00000358081 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:bag3_human(display_long)|uniprotkb:Bcl-2-associated athanogene 3(gene name synonym)|uniprotkb:Bcl-2-binding protein Bis(gene name synonym)|uniprotkb:Docking protein CAIR-1(gene name synonym)|uniprotkb:BAG3(gene name)|psi-mi:BAG3(display_short)|uniprotkb:BIS(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_004272.2|ensembl:ENSG00000151929(gene)|ensembl:ENST00000369085(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007420"(brain development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0021510"(spinal cord development)|go:"GO:0030018"(Z disc)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036020|interpro:IPR036533|interpro:IPR039773|mint:O95817|reactome:R-HSA-3371453|go:"GO:0101031"(chaperone complex)|dip:DIP-41273N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Ld26VRSMJghXG/U98A76RijSDBc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UNX3 - intact:EBI-2949703|ensembl:ENSP00000265100|ensembl:ENSP00000428177|ensembl:ENSP00000428223|ensembl:ENSP00000430147|uniprotkb:B3KY82|uniprotkb:D3DQM0 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rl26l_human(display_long)|uniprotkb:RPL26L1(gene name)|psi-mi:RPL26L1(display_short)|uniprotkb:RPL26P1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL24-like 1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000037241(gene)|ensembl:ENST00000265100(transcript)|ensembl:ENST00000519239(transcript)|ensembl:ENST00000519974(transcript)|ensembl:ENST00000521476(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:Q9UNX3|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-2408557|refseq:NP_057177.1|refseq:XP_011532867.1|refseq:NP_001304909.1|refseq:NP_001304910.1|refseq:NP_001304911.1|refseq:XP_016865008.1|refseq:XP_016865009.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:dny/DWK4MvWD3FUJvW5+KGI3iJI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96CS3 - intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P18621 - intact:EBI-726937|uniprotkb:Q6NZ54|uniprotkb:Q7M4M5|uniprotkb:Q3KQW2|uniprotkb:B2R4H3|uniprotkb:B4E3C2|uniprotkb:B5ME31|uniprotkb:J3QL51|ensembl:ENSP00000462023|ensembl:ENSP00000462385|ensembl:ENSP00000463842|ensembl:ENSP00000480555|ensembl:ENSP00000482577 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rl17_human(display_long)|uniprotkb:60S ribosomal protein L23(gene name synonym)|uniprotkb:PD-1(gene name synonym)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short)|uniprotkb:Large ribosomal subunit protein uL22(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000976.1|refseq:NP_001030178.1|refseq:NP_001186269.1|refseq:NP_001186270.1|refseq:NP_001186271.1|refseq:NP_001186272.1|refseq:NP_001186273.1|refseq:NP_001186274.1|ensembl:ENSG00000265681(gene)|ensembl:ENST00000579248(transcript)|ensembl:ENST00000579408(transcript)|ensembl:ENST00000580261(transcript)|ensembl:ENST00000618613(transcript)|ensembl:ENST00000618619(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394|mint:P18621|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:/i0W3WoeFakz+8R/YMYf2JQZytI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P31943 - intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O75306 - intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96EX1 - intact:EBI-2874543|ensembl:ENSP00000428541|ensembl:ENSP00000428585|ensembl:ENSP00000428984|ensembl:ENSP00000430198|ensembl:ENSP00000430285|uniprotkb:Q52LP9|uniprotkb:Q8NCB4|uniprotkb:D3DPR5|uniprotkb:Q49AP7 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:sim12_human(display_long)|uniprotkb:SMIM12(gene name)|psi-mi:SMIM12(display_short)|uniprotkb:C1orf212(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000163866(gene)|ensembl:ENST00000417239(transcript)|ensembl:ENST00000423898(transcript)|ensembl:ENST00000446026(transcript)|ensembl:ENST00000456842(transcript)|ensembl:ENST00000521580(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031933|refseq:XP_011538855.1|refseq:XP_011538857.1|refseq:NP_001307190.1|refseq:NP_001158296.1|refseq:NP_001158297.1|refseq:NP_612437.3|refseq:XP_005270460.1|refseq:XP_016855655.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:qeuRSIWo2rJvSDDvexjGg07txg89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O60884 - intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9H307 - intact:EBI-681904|uniprotkb:Q9UQR9|uniprotkb:O60899|uniprotkb:Q53EM7|uniprotkb:Q6P5X4|uniprotkb:Q7KYL1|uniprotkb:Q99738|uniprotkb:Q9UHZ9|uniprotkb:B4DZX8|ensembl:ENSP00000216832 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pinin_human(display_long)|uniprotkb:140 kDa nuclear and cell adhesion-related phosphoprotein(gene name synonym)|uniprotkb:Domain-rich serine protein(gene name synonym)|uniprotkb:Melanoma metastasis clone A protein(gene name synonym)|uniprotkb:Desmosome-associated protein(gene name synonym)|uniprotkb:SR-like protein(gene name synonym)|uniprotkb:Nuclear protein SDK3(gene name synonym)|uniprotkb:PNN(gene name)|psi-mi:PNN(display_short)|uniprotkb:DRS(gene name synonym)|uniprotkb:MEMA(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002678.2|dip:DIP-32950N|ensembl:ENSG00000100941(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030057"(desmosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006786(Pinin/SDK/memA protein)|interpro:IPR006787(Pinin/SDK)|interpro:IPR039853|mint:Q9H307|ensembl:ENST00000216832(transcript) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:1pAhD0z8tks+HkWaYWkdMmSjk3s9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q08554 - intact:EBI-2371346|uniprotkb:Q9HB01|ensembl:ENSP00000257198 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:dsc1_human(display_long)|uniprotkb:DSC1(gene name)|psi-mi:DSC1(display_short)|uniprotkb:CDHF1(gene name synonym)|uniprotkb:Desmosomal glycoprotein 2/3(gene name synonym)|uniprotkb:Cadherin family member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_004939.1|refseq:NP_077739.1|ensembl:ENSG00000134765(gene)|ensembl:ENST00000257198(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030057"(desmosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|rcsb pdb:5IRY|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:dxtPfdDnZFaelPwT5bV8k/ZobSw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O75438 - intact:EBI-744216|uniprotkb:A0AV68|ensembl:ENSP00000330787|ensembl:ENSP00000450776|ensembl:ENSP00000451090|ensembl:ENSP00000475170 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ndub1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MNLL subunit(gene name synonym)|uniprotkb:Complex I-MNLL(gene name synonym)|uniprotkb:NDUFB1(gene name)|psi-mi:NDUFB1(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_004536.2|ensembl:ENSG00000183648(gene)|ensembl:ENST00000329559(transcript)|ensembl:ENST00000553514(transcript)|ensembl:ENST00000555441(transcript)|ensembl:ENST00000605997(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR012575(MNLL subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:FU3iytC6Yu5qzxy8Yim4y6wSVqc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P09651 - intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P01876 - intact:EBI-727651|ensembl:ENSP00000374989|ensembl:ENSP00000488021 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:igha1_human(display_long)|uniprotkb:IGHA1(gene name)|psi-mi:IGHA1(display_short)|uniprotkb:Ig alpha-1 chain C region(gene name synonym)|uniprotkb:Ig alpha-1 chain C region BUR(gene name synonym)|uniprotkb:Ig alpha-1 chain C region TRO(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000211895(gene)|ensembl:ENSG00000282633(gene)|ensembl:ENST00000390547(transcript)|ensembl:ENST00000633714(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:0071748"(monomeric IgA immunoglobulin complex)|go:"GO:0071751"(secretory IgA immunoglobulin complex)|go:"GO:0071752"(secretory dimeric IgA immunoglobulin complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1IGA|rcsb pdb:1OW0|rcsb pdb:2ESG|rcsb pdb:2QEJ|rcsb pdb:3CHN|rcsb pdb:6LX3|rcsb pdb:6LXW|rcsb pdb:6UE7|rcsb pdb:6XJA|reactome:R-HSA-202733|reactome:R-HSA-2168880|go:"GO:0070062"(extracellular exosome) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Mystbtg9uttxFXl//LGdoM32po09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9Y2S7 - intact:EBI-713000|ensembl:ENSP00000475924|uniprotkb:Q96JE4|uniprotkb:B2R846 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pdip2_human(display_long)|uniprotkb:38 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short)|uniprotkb:PDIP38(gene name synonym)|uniprotkb:POLD4(gene name synonym)|uniprotkb:HSPC017(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000004142(gene)|ensembl:ENST00000540200(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1990874"(vascular associated smooth muscle cell proliferation)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|mint:Q9Y2S7|rcsb pdb:6Z9C|refseq:NP_056399.1|refseq:NP_001277074.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:eZmek2xqphKowjP6zwsH6ydfz3g9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q5HYK3 - intact:EBI-12577722|ensembl:ENSP00000288532|uniprotkb:B2RDU9|uniprotkb:B3GK62|uniprotkb:B4DEJ4|uniprotkb:Q32Q28|uniprotkb:Q53HH0|uniprotkb:Q96LV1|uniprotkb:Q9BSP8 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:coq5_human(display_long)|uniprotkb:COQ5(gene name)|psi-mi:COQ5(display_short)|uniprotkb:Ubiquinone biosynthesis methyltransferase COQ5(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000110871(gene)|ensembl:ENST00000288532(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032259"(methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043333"(2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity)|go:"GO:0043430"(2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity)|interpro:IPR004033(UbiE/COQ5 methyltransferase)|interpro:IPR023576|interpro:IPR029063|mint:Q5HYK3|reactome:R-HSA-2142789|refseq:NP_115690.3 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:zyV+GL8MivuqPdn5qkE6zEjYCkc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P12694 - intact:EBI-1029053|uniprotkb:Q16034|uniprotkb:Q16472|uniprotkb:B4DP47|uniprotkb:E7EW46|ensembl:ENSP00000269980 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:odba_human(display_long)|uniprotkb:BCKDHA(gene name)|psi-mi:BCKDHA(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000700.1|ensembl:ENSG00000248098(gene)|ensembl:ENST00000269980(transcript)|go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR034616|rcsb pdb:1DTW|rcsb pdb:1OLS|rcsb pdb:1OLU|rcsb pdb:1OLX|rcsb pdb:1U5B|rcsb pdb:1V11|rcsb pdb:1V16|rcsb pdb:1V1M|rcsb pdb:1V1R|rcsb pdb:1WCI|rcsb pdb:1X7W|rcsb pdb:1X7X|rcsb pdb:1X7Y|rcsb pdb:1X7Z|rcsb pdb:1X80|rcsb pdb:2BEU|rcsb pdb:2BEV|rcsb pdb:2BEW|rcsb pdb:2BFB|rcsb pdb:2BFC|rcsb pdb:2BFD|rcsb pdb:2BFE|rcsb pdb:2BFF|rcsb pdb:2J9F|reactome:R-HSA-389661|reactome:R-HSA-70895|refseq:NP_001158255.1|dip:DIP-6146N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:dfjLnS4YI8gwCQljkXL3W24I/DY9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q66PJ3 - intact:EBI-2683099|uniprotkb:Q9NR05|uniprotkb:Q4F966|uniprotkb:Q9P2R9|uniprotkb:Q96BI2|uniprotkb:Q504R8|uniprotkb:A4UCR8|uniprotkb:B3V0L0|uniprotkb:B3V0L1 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ar6p4_human(display_long)|uniprotkb:HSP-975(gene name synonym)|uniprotkb:HSVI-binding protein(gene name synonym)|uniprotkb:SR-15(gene name synonym)|uniprotkb:SRp25(gene name synonym)|uniprotkb:Splicing factor SRrp37(gene name synonym)|uniprotkb:ARL6IP4(gene name)|psi-mi:ARL6IP4(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR019532|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|refseq:NP_001002251.2|refseq:NP_001002252.2|refseq:NP_001265307.1|refseq:NP_001265308.1|refseq:NP_001265309.1|refseq:NP_061164.3|refseq:NP_057722.3|mint:Q66PJ3 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:ZNWWhsvMwbPRZb3BlP50N3hc4Ls9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P82933 - intact:EBI-721385|intact:EBI-1049991|uniprotkb:Q6PG40|ensembl:ENSP00000258455 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rt09_human(display_long)|uniprotkb:MRPS9(gene name)|psi-mi:MRPS9(display_short)|uniprotkb:RPMS9(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS9m(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_872578.1|ensembl:ENSG00000135972(gene)|ensembl:ENST00000258455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P82933|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSE go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:XNB4GL84eYgYFEB3WxOtoD3Ub989606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O76094 - intact:EBI-1058850|ensembl:ENSP00000495128|intact:EBI-2654733|uniprotkb:G5E9Z8|uniprotkb:Q7Z3C0 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:srp72_human(display_long)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_008878.3|refseq:NP_001254651.1|ensembl:ENSG00000174780(gene)|ensembl:ENST00000642900(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030911"(TPR domain binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR019734|interpro:IPR026270|interpro:IPR031545|mint:O76094|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:5WRW|rcsb pdb:7NFX|reactome:R-HSA-1799339 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:NJfyOcmKiBWszQsH0EQotsdwhU09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9UKM9 - intact:EBI-714796|uniprotkb:Q14621|uniprotkb:Q2M365|uniprotkb:Q5QPL8|uniprotkb:Q9BQX6|uniprotkb:Q9UJE3|ensembl:ENSP00000246194 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:raly_human(display_long)|uniprotkb:hnRNP associated with lethal yellow protein homolog(gene name synonym)|uniprotkb:Autoantigen p542(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 2(gene name synonym)|uniprotkb:RALY(gene name)|psi-mi:RALY(display_short)|uniprotkb:P542(gene name synonym)|uniprotkb:HNRPCL2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:XP_011526996.1|refseq:XP_011526997.1|ensembl:ENSG00000125970(gene)|ensembl:ENST00000246194(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR034502|interpro:IPR035979|mint:Q9UKM9|rcsb pdb:1WF1|refseq:NP_031393.2|refseq:NP_057951.1|refseq:XP_005260391.1|refseq:XP_005260393.1|refseq:XP_016883220.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:3hd0n2UW0FSRNvSJa2mqflVeorc9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9Y2R9 - intact:EBI-1054973|uniprotkb:Q53GD6|uniprotkb:B2R9N5|ensembl:ENSP00000245539 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rt07_human(display_long)|uniprotkb:bMRP-27a(gene name synonym)|uniprotkb:MRPS7(gene name)|psi-mi:MRPS7(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS7m(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_057055.2|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR023798|interpro:IPR036823|mint:Q9Y2R9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125445(gene)|ensembl:ENST00000245539(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:hrz2XVS38Ex1z125QFx/n9oPsys9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q04828 - intact:EBI-2116455|uniprotkb:P52896|uniprotkb:Q5SR15|uniprotkb:Q7M4N2|uniprotkb:Q9UCX2|ensembl:ENSP00000370254 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ak1c1_human(display_long)|uniprotkb:AKR1C1(gene name)|psi-mi:AKR1C1(display_short)|uniprotkb:DDH(gene name synonym)|uniprotkb:DDH1(gene name synonym)|uniprotkb:20-alpha-hydroxysteroid dehydrogenase(gene name synonym)|uniprotkb:Chlordecone reductase homolog HAKRC(gene name synonym)|uniprotkb:High-affinity hepatic bile acid-binding protein(gene name synonym)|uniprotkb:Dihydrodiol dehydrogenase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001344.2|ensembl:ENSG00000187134(gene)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007586"(digestion)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016229"(steroid dehydrogenase activity)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0018636"(phenanthrene 9,10-monooxygenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032052"(bile acid binding)|go:"GO:0033703"(3beta-hydroxy-5beta-steroid dehydrogenase activity)|go:"GO:0035410"(dihydrotestosterone 17-beta-dehydrogenase activity)|go:"GO:0042448"(progesterone metabolic process)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0046683"(response to organophosphorus)|go:"GO:0047006"(17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity)|go:"GO:0047023"(androsterone dehydrogenase activity)|go:"GO:0047024"(5alpha-androstane-3beta,17beta-diol dehydrogenase activity)|go:"GO:0047042"("androsterone dehydrogenase (B-specific) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|go:"GO:0047086"(ketosteroid monooxygenase activity)|go:"GO:0047115"(trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity)|go:"GO:0047718"(indanol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071395"(cellular response to jasmonic acid stimulus)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|interpro:IPR044482|rcsb pdb:1MRQ|rcsb pdb:3C3U|rcsb pdb:3GUG|rcsb pdb:3NTY|rcsb pdb:4YVP|rcsb pdb:6A7A|rcsb pdb:6IJX|reactome:R-HSA-193368|reactome:R-HSA-193775|reactome:R-HSA-193807|reactome:R-HSA-975634|ensembl:ENST00000380872(transcript) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:ZjkfheYyp49NbEmyiDrKPJc8K6k9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96HS1 - intact:EBI-713608|uniprotkb:Q96JB0|intact:EBI-2555528|ensembl:ENSP00000438465|uniprotkb:C9IZY7|uniprotkb:A9LN06 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:pgam5_human(display_long)|uniprotkb:Bcl-XL-binding protein v68(gene name synonym)|uniprotkb:PGAM5(gene name)|psi-mi:PGAM5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001164014.1|refseq:NP_612642.2|ensembl:ENSG00000247077(gene)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016791"(phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q96HS1|rcsb pdb:3MXO|rcsb pdb:3O0T|rcsb pdb:5MUF|rcsb pdb:6CNI|rcsb pdb:6CNL|reactome:R-HSA-8934903|ensembl:ENST00000498926(transcript)|dip:DIP-50735N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:prE0I+tNIEjN9Y1NBZbh51DY2+Q9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P30837 - intact:EBI-1237410|uniprotkb:Q8WX76|uniprotkb:Q9BV45|uniprotkb:B2R8F0|ensembl:ENSP00000366927 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:al1b1_human(display_long)|uniprotkb:ALDH1B1(gene name)|psi-mi:ALDH1B1(display_short)|uniprotkb:ALDH5(gene name synonym)|uniprotkb:ALDHX(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 1 member B1(gene name synonym)|uniprotkb:Aldehyde dehydrogenase 5(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000683.3|ensembl:ENSG00000137124(gene)|ensembl:ENST00000377698(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0051287"(NAD binding)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P30837|reactome:R-HSA-71384|go:"GO:0005654"(nucleoplasm) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:esHIXlANuM3Gmcr8ldyTq/nAyUM9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P06733 - intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NX63 - intact:EBI-743375|ensembl:ENSP00000262570 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:mic19_human(display_long)|uniprotkb:CHCHD3(gene name)|psi-mi:CHCHD3(display_short)|uniprotkb:MINOS3(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:MIC19(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - go:"GO:0008053"(mitochondrial fusion)|refseq:NP_060282.1|refseq:NP_001304106.1|ensembl:ENSG00000106554(gene)|ensembl:ENST00000262570(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|mint:Q9NX63|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0019902"(phosphatase binding) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Ox0+PoTPYwxw8cKNqpzvSCg+Smg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P62937 - intact:EBI-437708|uniprotkb:P05092|uniprotkb:Q3KQW3|uniprotkb:Q6IBU5|uniprotkb:Q96IX3|uniprotkb:Q9BRU4|uniprotkb:Q9BTY9|uniprotkb:Q9UC61|uniprotkb:Q567Q0|ensembl:ENSP00000419425|uniprotkb:A8K220 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:ppia_human(display_long)|uniprotkb:Cyclophilin A(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:PPIA(gene name)|psi-mi:PPIA(display_short)|uniprotkb:CYPA(gene name synonym)|uniprotkb:Rotamase A(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_066953.1|interpro:IPR029000|mint:P62937|rcsb pdb:1AK4|rcsb pdb:1AWQ|rcsb pdb:1AWR|rcsb pdb:1AWS|rcsb pdb:1AWT|rcsb pdb:1AWU|rcsb pdb:1AWV|rcsb pdb:1BCK|rcsb pdb:1CWA|rcsb pdb:1CWB|rcsb pdb:1CWC|rcsb pdb:1CWF|rcsb pdb:1CWH|rcsb pdb:1CWI|rcsb pdb:1CWJ|rcsb pdb:1CWK|rcsb pdb:1CWL|rcsb pdb:1CWM|interpro:IPR024936|rcsb pdb:1CWO|rcsb pdb:1FGL|rcsb pdb:2N0T|rcsb pdb:2RMA|rcsb pdb:1M63|rcsb pdb:2RMB|rcsb pdb:2X25|rcsb pdb:2X2A|rcsb pdb:2X2C|rcsb pdb:2X2D|rcsb pdb:1M9C|rcsb pdb:1M9D|rcsb pdb:1M9E|rcsb pdb:2XGY|rcsb pdb:3CYH|rcsb pdb:3CYS|rcsb pdb:3K0M|rcsb pdb:3K0N|rcsb pdb:3K0O|rcsb pdb:3K0P|rcsb pdb:3K0Q|rcsb pdb:3K0R|rcsb pdb:3ODI|rcsb pdb:3ODL|rcsb pdb:1M9F|rcsb pdb:3RDD|rcsb pdb:1M9X|rcsb pdb:1M9Y|rcsb pdb:4CYH|rcsb pdb:4IPZ|rcsb pdb:4N1M|rcsb pdb:4N1N|rcsb pdb:1MF8|rcsb pdb:4N1O|rcsb pdb:4N1P|rcsb pdb:4N1Q|rcsb pdb:1MIK|rcsb pdb:1NMK|rcsb pdb:1OCA|rcsb pdb:1RMH|rcsb pdb:1VBS|rcsb pdb:1VBT|rcsb pdb:1W8L|rcsb pdb:1W8M|rcsb pdb:1W8V|rcsb pdb:1YND|rcsb pdb:1ZKF|rcsb pdb:2ALF|rcsb pdb:2CPL|rcsb pdb:2CYH|rcsb pdb:2MS4|rcsb pdb:2MZU|rcsb pdb:4N1R|rcsb pdb:4N1S|rcsb pdb:4YUG|rcsb pdb:4YUH|refseq:NP_001287910.1|reactome:R-HSA-210991|reactome:R-HSA-6798695|reactome:R-HSA-8950505|reactome:R-HSA-2025928|ensembl:ENSG00000196262(gene)|ensembl:ENST00000468812(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0019076"(viral release from host cell)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031982"(vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046790"(virion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0061944"(negative regulation of protein K48-linked ubiquitination)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903901"(negative regulation of viral life cycle)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|go:"GO:0005178"(integrin binding)|rcsb pdb:4YUI|rcsb pdb:4YUJ|rcsb pdb:4YUK|rcsb pdb:4YUL|rcsb pdb:4YUM|rcsb pdb:4YUN|rcsb pdb:4YUO|rcsb pdb:4YUP|rcsb pdb:5CYH|rcsb pdb:5F66|rcsb pdb:5FJB|rcsb pdb:5KUL|rcsb pdb:5KUN|rcsb pdb:5KUO|rcsb pdb:5KUQ|rcsb pdb:5KUR|rcsb pdb:5KUS|rcsb pdb:5KUU|rcsb pdb:5KUV|rcsb pdb:5KUW|rcsb pdb:5KUZ|rcsb pdb:5KV0|rcsb pdb:5KV1|rcsb pdb:5KV2|rcsb pdb:5KV3|rcsb pdb:5KV4|rcsb pdb:5KV5|rcsb pdb:5KV6|rcsb pdb:5KV7|rcsb pdb:5LUD|rcsb pdb:5NOQ|rcsb pdb:5NOR|rcsb pdb:5NOT|rcsb pdb:5NOU|rcsb pdb:5NOV|rcsb pdb:5NOW|rcsb pdb:5NOX|rcsb pdb:5NOY|rcsb pdb:5NOZ|rcsb pdb:5T9U|rcsb pdb:5T9W|rcsb pdb:5T9Z|rcsb pdb:5TA2|rcsb pdb:5TA4|rcsb pdb:5WC7|rcsb pdb:6BTA|rcsb pdb:6GJI|rcsb pdb:6GJJ|rcsb pdb:6GJL|rcsb pdb:6GJM|rcsb pdb:6GJN|rcsb pdb:6GJP|rcsb pdb:6GJR|rcsb pdb:6GJY|rcsb pdb:6GS6|rcsb pdb:6I42|rcsb pdb:6U5C|rcsb pdb:6U5D|rcsb pdb:6U5E|rcsb pdb:6U5G|rcsb pdb:6X3R|rcsb pdb:6X3Y|rcsb pdb:5NOS|rcsb pdb:6X4N|rcsb pdb:6X4O|rcsb pdb:6X4P|rcsb pdb:6X4Q|rcsb pdb:6Y9V|rcsb pdb:6Y9W|rcsb pdb:6Y9X|rcsb pdb:6Y9Y|rcsb pdb:6Y9Z|rcsb pdb:6ZDJ|rcsb pdb:7ABT|reactome:R-HSA-114608|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-173107|rcsb pdb:6X4M|reactome:R-HSA-175474|reactome:R-HSA-180689|dip:DIP-6080N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:dr4EVxcO+sqTPBqsQcydRn+rHoo9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q14103 - intact:EBI-299674|ensembl:ENSP00000313199|uniprotkb:P07029|uniprotkb:Q01858|uniprotkb:Q14100|uniprotkb:Q14101|uniprotkb:Q14102|uniprotkb:Q4W5A1|uniprotkb:A8K9J2|uniprotkb:Q9UCE8|uniprotkb:Q9UCE9 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hnrpd_human(display_long)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000138668(gene)|ensembl:ENST00000313899(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q14103|rcsb pdb:1HD0|rcsb pdb:1HD1|rcsb pdb:1IQT|rcsb pdb:1WTB|rcsb pdb:1X0F|rcsb pdb:2Z5N|rcsb pdb:5IM0|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|reactome:R-HSA-450408|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001003810.1|refseq:NP_002129.2|refseq:NP_112737.1|refseq:NP_112738.1|dip:DIP-31163N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:O15230 - intact:EBI-725060|uniprotkb:Q8WZA7|uniprotkb:Q9H1P1|uniprotkb:Q8TDF8|uniprotkb:Q5U4N9|ensembl:ENSP00000252999 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:lama5_human(display_long)|uniprotkb:LAMA5(gene name)|psi-mi:LAMA5(display_short)|uniprotkb:KIAA0533(gene name synonym)|uniprotkb:KIAA1907(gene name synonym)|uniprotkb:Laminin-10 subunit alpha(gene name synonym)|uniprotkb:Laminin-11 subunit alpha(gene name synonym)|uniprotkb:Laminin-15 subunit alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_005551.3|ensembl:ENSG00000130702(gene)|ensembl:ENST00000252999(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001942"(hair follicle development)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005610"(laminin-5 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016477"(cell migration)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|mint:O15230|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-6785807|reactome:R-HSA-8874081 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:rSTl5zwwQKcbd20buKGffFtl3jI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q96EY1 - intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375|ensembl:ENSP00000477570 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000262375(transcript)|ensembl:ENST00000612103(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|dip:DIP-33870N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NYF8 - intact:EBI-437804|ensembl:ENSP00000435210|uniprotkb:Q86WY0|uniprotkb:Q14673|uniprotkb:Q86WU6|uniprotkb:B7ZM58|uniprotkb:A2RU75|uniprotkb:E1P586 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:bclf1_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 1(gene name synonym)|uniprotkb:BCLAF1(gene name)|psi-mi:BCLAF1(display_short)|uniprotkb:BTF(gene name synonym)|uniprotkb:KIAA0164(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000029363(gene)|ensembl:ENST00000531224(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR026668|interpro:IPR029199|mint:Q9NYF8|refseq:NP_001070908.1|refseq:NP_001070909.1|refseq:NP_055554.1|refseq:NP_001287967.1 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:v6qbjyjKVCv0B/olkjQfTPKWqBw9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P11047 - intact:EBI-714904|uniprotkb:Q5VYE7|ensembl:ENSP00000258341 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:lamc1_human(display_long)|uniprotkb:Laminin B2 chain(gene name synonym)|uniprotkb:LAMC1(gene name)|psi-mi:LAMC1(display_short)|uniprotkb:LAMB2(gene name synonym)|uniprotkb:Laminin-1 subunit gamma(gene name synonym)|uniprotkb:Laminin-2 subunit gamma(gene name synonym)|uniprotkb:Laminin-3 subunit gamma(gene name synonym)|uniprotkb:Laminin-4 subunit gamma(gene name synonym)|uniprotkb:Laminin-6 subunit gamma(gene name synonym)|uniprotkb:Laminin-7 subunit gamma(gene name synonym)|uniprotkb:Laminin-8 subunit gamma(gene name synonym)|uniprotkb:Laminin-9 subunit gamma(gene name synonym)|uniprotkb:Laminin-10 subunit gamma(gene name synonym)|uniprotkb:Laminin-11 subunit gamma(gene name synonym)|uniprotkb:S-laminin subunit gamma(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|mint:P11047|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9619665|go:"GO:0070062"(extracellular exosome)|refseq:NP_002284.3|ensembl:ENSG00000135862(gene)|ensembl:ENST00000258341(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007492"(endoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:2JMPODzaiqmTaLlmjdgvlv8e8+M9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9NS25 - intact:EBI-17197485|uniprotkb:A0A0G2JJ56|uniprotkb:B2RPP2|uniprotkb:Q32WQ7|uniprotkb:Q5JYZ7|uniprotkb:Q8TAD5|ensembl:ENSP00000405202 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:spnxb_human(display_long)|uniprotkb:SPANXB1(gene name)|psi-mi:SPANXB1(display_short)|uniprotkb:SPANXB(gene name synonym)|uniprotkb:SPANXB2(gene name synonym)|uniprotkb:SPANXF1(gene name synonym)|uniprotkb:Cancer/testis antigen 11.2(gene name synonym)|uniprotkb:Nuclear-associated protein SPAN-Xb(gene name synonym)|uniprotkb:SPANX family member B1(gene name synonym)|uniprotkb:SPANX family member F1(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_115850.2|ensembl:ENSG00000227234(gene)|ensembl:ENST00000449283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007286"(spermatid development)|interpro:IPR010007(Sperm associated with nucleus, X chromosome) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:MqK/CtacSJK1sZdA6O1hGQ6btcE9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P82675 - intact:EBI-1054287|uniprotkb:Q96LJ6|uniprotkb:Q9BWI4|uniprotkb:Q9BYC4|uniprotkb:Q4ZFY5|ensembl:ENSP00000272418 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rt05_human(display_long)|uniprotkb:MRPS5(gene name)|psi-mi:MRPS5(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS5m(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_114108.1|ensembl:ENSG00000144029(gene)|ensembl:ENST00000272418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|mint:P82675|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6RW5|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:l+aZgmDVWWimuUiH4IS4FG1cwlQ9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P04083 - intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response) go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:QKmqz+UsAof35B/so2qKLQjn2v09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P55268 - intact:EBI-2529769|uniprotkb:Q16321|ensembl:ENSP00000307156|ensembl:ENSP00000388325 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:lamb2_human(display_long)|uniprotkb:Laminin-4 subunit beta(gene name synonym)|uniprotkb:Laminin-7 subunit beta(gene name synonym)|uniprotkb:Laminin-9 subunit beta(gene name synonym)|uniprotkb:Laminin-11 subunit beta(gene name synonym)|uniprotkb:Laminin-14 subunit beta(gene name synonym)|uniprotkb:Laminin-15 subunit beta(gene name synonym)|uniprotkb:S-laminin subunit beta(gene name synonym)|uniprotkb:LAMB2(gene name)|psi-mi:LAMB2(display_short)|uniprotkb:LAMS(gene name synonym)|uniprotkb:Laminin-3 subunit beta(gene name synonym)|uniprotkb:Laminin B1s chain(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000172037(gene)|ensembl:ENST00000305544(transcript)|ensembl:ENST00000418109(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005608"(laminin-3 complex)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0014002"(astrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016477"(cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043256"(laminin complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0048677"(axon extension involved in regeneration)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0072249"(metanephric glomerular visceral epithelial cell development)|go:"GO:0072274"(metanephric glomerular basement membrane development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P55268|reactome:R-HSA-3000157|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-3000171|refseq:NP_002283.3|refseq:XP_005265184.1|dip:DIP-42106N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:LY1lt2hyTcFN+x4GtvfzufChDF89606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q6NUK1 - intact:EBI-4289949|uniprotkb:Q705K4|uniprotkb:B7ZAI9|uniprotkb:Q5T331|uniprotkb:Q9P129|uniprotkb:Q5T485|uniprotkb:Q6PJJ9|ensembl:ENSP00000457733|ensembl:ENSP00000491572 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:scmc1_human(display_long)|uniprotkb:SLC25A24(gene name)|psi-mi:SLC25A24(display_short)|uniprotkb:APC1(gene name synonym)|uniprotkb:MCSC1(gene name synonym)|uniprotkb:SCAMC1(gene name synonym)|uniprotkb:Mitochondrial ATP-Mg/Pi carrier protein 1(gene name synonym)|uniprotkb:"Mitochondrial Ca(2+)-dependent solute carrier protein 1"(gene name synonym)|uniprotkb:Small calcium-binding mitochondrial carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 24(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_037518.3|refseq:NP_998816.1|ensembl:ENSG00000085491(gene)|ensembl:ENSG00000284468(gene)|ensembl:ENST00000565488(transcript)|ensembl:ENST00000640416(transcript)|go:"GO:0005347"(ATP transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0010941"(regulation of cell death)|go:"GO:0015867"(ATP transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002167(Graves disease carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR018247|interpro:IPR023395|mint:Q6NUK1|rcsb pdb:4N5X|rcsb pdb:4ZCU|rcsb pdb:4ZCV go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:2zVynZiDVY5UzziL6TAmqK/fkB09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q92665 - intact:EBI-720602|uniprotkb:Q8WTV8|uniprotkb:Q5VYC8|uniprotkb:B2RCS3|ensembl:ENSP00000315397 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rt31_human(display_long)|uniprotkb:Imogen 38(gene name synonym)|uniprotkb:MRPS31(gene name)|psi-mi:MRPS31(display_short)|uniprotkb:IMOGN38(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS31(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_005821.2|ensembl:ENSG00000102738(gene)|ensembl:ENST00000323563(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|mint:Q92665|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Le0Lq+WW56dP5NLuMB2eKFeg6b09606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q9HC84 - intact:EBI-21574356|uniprotkb:O00447|uniprotkb:O00573|uniprotkb:O14985|uniprotkb:O15494|uniprotkb:O95291|uniprotkb:O95451|uniprotkb:Q14881|uniprotkb:Q7M4S5|uniprotkb:Q99552|uniprotkb:Q9UE28|ensembl:ENSP00000436812 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:muc5b_human(display_long)|uniprotkb:Cervical mucin(gene name synonym)|uniprotkb:High molecular weight salivary mucin MG1(gene name synonym)|uniprotkb:Mucin-5 subtype B, tracheobronchial(gene name synonym)|uniprotkb:Sublingual gland mucin(gene name synonym)|uniprotkb:MUC5B(gene name)|psi-mi:MUC5B(display_short)|uniprotkb:MUC5(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002449.2|ensembl:ENSG00000117983(gene)|ensembl:ENST00000529681(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR025155|interpro:IPR036084|reactome:R-HSA-5083625|reactome:R-HSA-5083632|reactome:R-HSA-5083636|reactome:R-HSA-5621480|reactome:R-HSA-913709|reactome:R-HSA-977068 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:vaS7kYhO+FKlPabeSiAtam81YoI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P62753 - intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:beDuXCIqL99V9JlVfpzx7MdpH689606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P35579 - intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P07910 - intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:Q86VM9 - intact:EBI-1045965|uniprotkb:Q96DG4|uniprotkb:Q96MP7|ensembl:ENSP00000301011 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:zch18_human(display_long)|uniprotkb:NHN1(gene name synonym)|uniprotkb:Nuclear protein NHN1(gene name synonym)|uniprotkb:ZC3H18(gene name)|psi-mi:ZC3H18(display_short) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22234251|imex:IM-27520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_001281269.1|ensembl:ENST00000301011(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0050779"(RNA destabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041367|mint:Q86VM9|ensembl:ENSG00000158545(gene)|ensembl:ENSP00000301011|refseq:NP_653205.3 go:"GO:0005634"(nucleus) caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:Supplementary Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-heparg)|taxid:9606(Homo sapiens hepatoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:H9lST8OLyCpyi5AWYqFYskL0ezI9606 rigid:O3RkGxR59BUp0bED9pRFCgTijI4 false strep ii tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-22235520 uniprotkb:P28370 - intact:EBI-2822460|uniprotkb:Q5JV41|uniprotkb:Q5JV42|ensembl:ENSP00000360163 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:smca1_human(display_long)|uniprotkb:SMARCA1(gene name)|psi-mi:SMARCA1(display_short)|uniprotkb:SNF2L(gene name synonym)|uniprotkb:SNF2L1(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA1(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit SNF2L(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-22235594|imex:IM-27520-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003060.2|refseq:NP_001269804.1|refseq:XP_006724845.1|refseq:XP_016885239.1|refseq:XP_005262518.1|dip:DIP-57685N|ensembl:ENSG00000102038(gene)|ensembl:ENST00000371122(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0090537"(CERF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044755|mint:P28370 - caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:1a, upper gel, lane iii|comment:Interaction detected in HUH7 cells transfected with viral protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:BBDJMLUdqadz6iXLKjLJto+XF5s9606 rigid:kG+z3gHawO1GYhT62otFr2oC8TY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-22235520 uniprotkb:O60264 - intact:EBI-352588|ensembl:ENSP00000283131 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:smca5_human(display_long)|uniprotkb:SMARCA5(gene name)|psi-mi:SMARCA5(display_short)|uniprotkb:SNF2H(gene name synonym)|uniprotkb:WCRF135(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-22235601|imex:IM-27520-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENST00000283131(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:O60264|rcsb pdb:6NE3|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5693565|reactome:R-HSA-606279|refseq:NP_003592.3|ensembl:ENSG00000153147(gene)|dip:DIP-33204N - caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:1a, lower gel, lane iii|comment:Interaction detected in HUH7 cells transfected with viral protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:XlXL5MRhAFlqHhGroPdm01lYEk89606 rigid:xaTZQo4A8LuY5Hlj7Yj0rzOqw78 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UIF8 uniprotkb:P28370 intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 intact:EBI-2822460|uniprotkb:Q5JV41|uniprotkb:Q5JV42|ensembl:ENSP00000360163 psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:smca1_human(display_long)|uniprotkb:SMARCA1(gene name)|psi-mi:SMARCA1(display_short)|uniprotkb:SNF2L(gene name synonym)|uniprotkb:SNF2L1(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA1(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit SNF2L(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22235607|imex:IM-27520-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 refseq:NP_003060.2|refseq:NP_001269804.1|refseq:XP_006724845.1|refseq:XP_016885239.1|refseq:XP_005262518.1|dip:DIP-57685N|ensembl:ENSG00000102038(gene)|ensembl:ENST00000371122(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0090537"(CERF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044755|mint:P28370 - - - figure legend:1a, lane ii|comment:Interaction detected in HUH7 cells not transfected with viral protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2019/11/29 2019/12/05 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rogid:BBDJMLUdqadz6iXLKjLJto+XF5s9606 rigid:JfelSEWmAjIeFssmmvIeKZuF9cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UIF8 uniprotkb:O60264 intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 intact:EBI-352588|ensembl:ENSP00000283131 psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:smca5_human(display_long)|uniprotkb:SMARCA5(gene name)|psi-mi:SMARCA5(display_short)|uniprotkb:SNF2H(gene name synonym)|uniprotkb:WCRF135(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22235607|imex:IM-27520-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 ensembl:ENST00000283131(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:O60264|rcsb pdb:6NE3|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5693565|reactome:R-HSA-606279|refseq:NP_003592.3|ensembl:ENSG00000153147(gene)|dip:DIP-33204N - - - figure legend:1a, lane ii|comment:Interaction detected in HUH7 cells not transfected with viral protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2019/11/29 2019/12/05 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rogid:XlXL5MRhAFlqHhGroPdm01lYEk89606 rigid:JfelSEWmAjIeFssmmvIeKZuF9cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UIF8 uniprotkb:P28370 intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 intact:EBI-2822460|uniprotkb:Q5JV41|uniprotkb:Q5JV42|ensembl:ENSP00000360163 psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:smca1_human(display_long)|uniprotkb:SMARCA1(gene name)|psi-mi:SMARCA1(display_short)|uniprotkb:SNF2L(gene name synonym)|uniprotkb:SNF2L1(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA1(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit SNF2L(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22235613|imex:IM-27520-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 refseq:NP_003060.2|refseq:NP_001269804.1|refseq:XP_006724845.1|refseq:XP_016885239.1|refseq:XP_005262518.1|dip:DIP-57685N|ensembl:ENSG00000102038(gene)|ensembl:ENST00000371122(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0090537"(CERF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044755|mint:P28370 - - - figure legend:1a, lane ii|comment:Interaction detected in HUH7 cells transfected with viral protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2019/11/29 2019/12/05 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rogid:BBDJMLUdqadz6iXLKjLJto+XF5s9606 rigid:oiNSs+uwGKS/Qm8FtghsPdz9hG0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UIF8 intact:EBI-22235520 intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 - psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22235613|imex:IM-27520-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 - - - caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." figure legend:1a, lane ii|comment:Interaction detected in HUH7 cells transfected with viral protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2019/11/29 2019/12/05 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rigid:oiNSs+uwGKS/Qm8FtghsPdz9hG0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UIF8 uniprotkb:O60264 intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 intact:EBI-352588|ensembl:ENSP00000283131 psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:smca5_human(display_long)|uniprotkb:SMARCA5(gene name)|psi-mi:SMARCA5(display_short)|uniprotkb:SNF2H(gene name synonym)|uniprotkb:WCRF135(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22235613|imex:IM-27520-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 ensembl:ENST00000283131(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:O60264|rcsb pdb:6NE3|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5693565|reactome:R-HSA-606279|refseq:NP_003592.3|ensembl:ENSG00000153147(gene)|dip:DIP-33204N - - - figure legend:1a, lane ii|comment:Interaction detected in HUH7 cells transfected with viral protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2019/11/29 2019/12/05 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rogid:XlXL5MRhAFlqHhGroPdm01lYEk89606 rigid:oiNSs+uwGKS/Qm8FtghsPdz9hG0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) intact:EBI-22235520 uniprotkb:P28370 - intact:EBI-2822460|uniprotkb:Q5JV41|uniprotkb:Q5JV42|ensembl:ENSP00000360163 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:smca1_human(display_long)|uniprotkb:SMARCA1(gene name)|psi-mi:SMARCA1(display_short)|uniprotkb:SNF2L(gene name synonym)|uniprotkb:SNF2L1(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA1(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit SNF2L(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22273844|imex:IM-27520-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_003060.2|refseq:NP_001269804.1|refseq:XP_006724845.1|refseq:XP_016885239.1|refseq:XP_005262518.1|dip:DIP-57685N|ensembl:ENSG00000102038(gene)|ensembl:ENST00000371122(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0090537"(CERF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044755|mint:P28370 - caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:1a, lane i|comment:Interaction detected in HUH7 cells transfected with viral protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2019/11/29 2019/12/05 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:BBDJMLUdqadz6iXLKjLJto+XF5s9606 rigid:Hkce/73LtO8RxRb4IYqUREgi4xs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-22235520 uniprotkb:O60264 - intact:EBI-352588|ensembl:ENSP00000283131 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:smca5_human(display_long)|uniprotkb:SMARCA5(gene name)|psi-mi:SMARCA5(display_short)|uniprotkb:SNF2H(gene name synonym)|uniprotkb:WCRF135(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22273844|imex:IM-27520-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENST00000283131(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:O60264|rcsb pdb:6NE3|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5693565|reactome:R-HSA-606279|refseq:NP_003592.3|ensembl:ENSG00000153147(gene)|dip:DIP-33204N - caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:1a, lane i|comment:Interaction detected in HUH7 cells transfected with viral protein.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2019/11/29 2019/12/05 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:XlXL5MRhAFlqHhGroPdm01lYEk89606 rigid:Hkce/73LtO8RxRb4IYqUREgi4xs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UIF8 intact:EBI-22235520 intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 - psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-22235671|imex:IM-27520-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 - - - caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." figure legend:2G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/11/29 2019/12/02 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rigid:w/wma87Fr1y3TTsaDCvlHtQMiB4 false his tag:n-n|sufficient binding region:2054-2168(IPR001487) strep ii tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UIF8 intact:EBI-22235520 intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 - psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:"MI:0096"(pull down) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-22235841|imex:IM-27520-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 - - - caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." figure legend:Supplementary figure 4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/11/29 2019/12/02 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rigid:w/wma87Fr1y3TTsaDCvlHtQMiB4 false his tag:n-n|sufficient binding region:2054-2168(IPR001487) strep ii tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-22235520 uniprotkb:Q9UIF8 - intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 psi-mi:shdag_hdv(display_short)|psi-mi:EBI-22235520(display_long) psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Abeywickrama-Samarakoon et al. (2019) pubmed:31964889|imex:IM-27520 taxid:12475(hdv)|taxid:12475(Hepatitis delta virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-22235852|imex:IM-27520-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 - caution:"The generic taxonomy identifier for hepatitis delta viruses was used for this entry because its specific isolate (genotype I, isolate HF27) was not available in the NCBI taxonomy tree. A more suitable taxID will be used once it is created at NCBI." - figure legend:3f|comment:Interaction detected in HUH7 cells transfected with viral protein. BAZ2B BRD also co-precipitated acetylated histone H3, which cannot be annotated as the exact identity of H3 is not known.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2019/11/29 2019/12/02 rogid:YL1j0kWqBMFHEmL8YeLSb38BN8812475 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rigid:w/wma87Fr1y3TTsaDCvlHtQMiB4 false mutation disrupting interaction strength:75-75 green fluorescent protein tag:n-n|sufficient binding region:1931..1931-2168 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot)