#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P30559 uniprotkb:Q92847-1 intact:EBI-11724233|uniprotkb:Q15071|ensembl:ENSP00000324270 intact:EBI-21459171|ensembl:ENSP00000241256 psi-mi:oxyr_human(display_long)|uniprotkb:OXTR(gene name)|psi-mi:OXTR(display_short) psi-mi:q92847-1(display_long)|uniprotkb:GH-releasing peptide receptor(gene name synonym)|uniprotkb:Ghrelin receptor(gene name synonym)|uniprotkb:GHSR(gene name)|psi-mi:GHSR(display_short) psi-mi:"MI:0663"(confocal microscopy) Wallace et al. (2019) pubmed:30582955|imex:IM-27216 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-21949858|imex:IM-27216-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000907.2|refseq:XP_011532064.1|ensembl:ENSG00000180914(gene)|ensembl:ENST00000316793(transcript)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0001992"(regulation of systemic arterial blood pressure by vasopressin)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004990"(oxytocin receptor activity)|go:"GO:0005000"(vasopressin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0032570"(response to progesterone)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0030431"(sleep)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0034059"(response to anoxia)|go:"GO:0032355"(response to estradiol)|go:"GO:0034097"(response to cytokine)|go:"GO:0035176"(social behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042711"(maternal behavior)|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042755"(eating behavior)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044849"(estrous cycle)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0048565"(digestive tract development)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0060406"(positive regulation of penile erection)|go:"GO:0060455"(negative regulation of gastric acid secretion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070474"(positive regulation of uterine smooth muscle contraction)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001817(Vasopressin receptor)|interpro:IPR002062(Oxytocin receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6TPK|reactome:R-HSA-388479|reactome:R-HSA-416476 intact:EBI-21495682(isoform-parent)|ensembl:ENSG00000121853(gene)|ensembl:ENST00000241256(transcript) go:"GO:0005737"(cytoplasm) - - figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2019/08/01 2019/08/05 rogid:e89klfpNQCOwfhTh3Jujc8s1iAU9606 rogid:G0sX69hZa1BC//6+Zg6QHxzcTHg9606 rigid:o3Wux3pC3SBAevrh++29/iwNDlg false green fluorescent protein tag:?-? red fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P30559 uniprotkb:Q92847-1 intact:EBI-11724233|uniprotkb:Q15071|ensembl:ENSP00000324270 intact:EBI-21459171|ensembl:ENSP00000241256 psi-mi:oxyr_human(display_long)|uniprotkb:OXTR(gene name)|psi-mi:OXTR(display_short) psi-mi:q92847-1(display_long)|uniprotkb:GH-releasing peptide receptor(gene name synonym)|uniprotkb:Ghrelin receptor(gene name synonym)|uniprotkb:GHSR(gene name)|psi-mi:GHSR(display_short) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Wallace et al. (2019) pubmed:30582955|imex:IM-27216 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-21949880|imex:IM-27216-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000907.2|refseq:XP_011532064.1|ensembl:ENSG00000180914(gene)|ensembl:ENST00000316793(transcript)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0001992"(regulation of systemic arterial blood pressure by vasopressin)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004990"(oxytocin receptor activity)|go:"GO:0005000"(vasopressin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0032570"(response to progesterone)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0030431"(sleep)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0034059"(response to anoxia)|go:"GO:0032355"(response to estradiol)|go:"GO:0034097"(response to cytokine)|go:"GO:0035176"(social behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042711"(maternal behavior)|go:"GO:0042713"(sperm ejaculation)|go:"GO:0042755"(eating behavior)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044849"(estrous cycle)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0048565"(digestive tract development)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0060406"(positive regulation of penile erection)|go:"GO:0060455"(negative regulation of gastric acid secretion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070474"(positive regulation of uterine smooth muscle contraction)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001817(Vasopressin receptor)|interpro:IPR002062(Oxytocin receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6TPK|reactome:R-HSA-388479|reactome:R-HSA-416476 intact:EBI-21495682(isoform-parent)|ensembl:ENSG00000121853(gene)|ensembl:ENST00000241256(transcript) - - - figure legend:Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293a)|taxid:9606(Homo sapiens) - 2019/08/01 2019/10/14 rogid:e89klfpNQCOwfhTh3Jujc8s1iAU9606 rogid:G0sX69hZa1BC//6+Zg6QHxzcTHg9606 rigid:o3Wux3pC3SBAevrh++29/iwNDlg false green fluorescent protein tag:?-? red fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)