#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O14618 uniprotkb:Q9NWV4 intact:EBI-11668690|uniprotkb:Q2M366|uniprotkb:Q8NEV0|ensembl:ENSP00000436318 intact:EBI-724109|ensembl:ENSP00000294360 psi-mi:ccs_human(display_long)|uniprotkb:CCS(gene name)|psi-mi:CCS(display_short)|uniprotkb:Superoxide dismutase copper chaperone(gene name synonym) psi-mi:czib_human(display_long)|uniprotkb:CZIB(gene name)|psi-mi:CZIB(display_short)|uniprotkb:C1orf123(gene name synonym)|uniprotkb:UPF0587 protein C1orf123(gene name synonym) psi-mi:"MI:0018"(two hybrid) Furukawa et al. (2017) pubmed:30260988|imex:IM-27658 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21460970|imex:IM-27658-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005116.1|ensembl:ENSG00000173992(gene)|ensembl:ENST00000533244(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045296"(cadherin binding)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036163|interpro:IPR036423|mint:O14618|rcsb pdb:1DO5|rcsb pdb:2CRL|rcsb pdb:2RSQ|rcsb pdb:6FN8|rcsb pdb:6FOL|rcsb pdb:6FON|rcsb pdb:6FP6|reactome:R-HSA-3299685 refseq:NP_060357.1|ensembl:ENSG00000162384(gene)|ensembl:ENST00000294360(transcript)|go:"GO:0008270"(zinc ion binding)|interpro:IPR008584(Protein of unknown function DUF866, eukaryotic)|rcsb pdb:5ZLQ|rcsb pdb:5ZRT|refseq:NP_001291688.1|refseq:NP_001291689.1 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/07/01 2019/07/01 rogid:r5pGUXbIewnEFuTqrKn78aG7N309606 rogid:rSzxgaF5mvNQbCzTTmoc6I2CBfo9606 rigid:fM+3+umvFmP9FMctgmdLLMwBI3Q false sufficient binding region:1..1-75..75 sufficient binding region:52-160 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14618 uniprotkb:Q9NWV4 intact:EBI-11668690|uniprotkb:Q2M366|uniprotkb:Q8NEV0|ensembl:ENSP00000436318 intact:EBI-724109|ensembl:ENSP00000294360 psi-mi:ccs_human(display_long)|uniprotkb:CCS(gene name)|psi-mi:CCS(display_short)|uniprotkb:Superoxide dismutase copper chaperone(gene name synonym) psi-mi:czib_human(display_long)|uniprotkb:CZIB(gene name)|psi-mi:CZIB(display_short)|uniprotkb:C1orf123(gene name synonym)|uniprotkb:UPF0587 protein C1orf123(gene name synonym) psi-mi:"MI:0018"(two hybrid) Furukawa et al. (2017) pubmed:30260988|imex:IM-27658 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21460988|imex:IM-27658-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005116.1|ensembl:ENSG00000173992(gene)|ensembl:ENST00000533244(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045296"(cadherin binding)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036163|interpro:IPR036423|mint:O14618|rcsb pdb:1DO5|rcsb pdb:2CRL|rcsb pdb:2RSQ|rcsb pdb:6FN8|rcsb pdb:6FOL|rcsb pdb:6FON|rcsb pdb:6FP6|reactome:R-HSA-3299685 refseq:NP_060357.1|ensembl:ENSG00000162384(gene)|ensembl:ENST00000294360(transcript)|go:"GO:0008270"(zinc ion binding)|interpro:IPR008584(Protein of unknown function DUF866, eukaryotic)|rcsb pdb:5ZLQ|rcsb pdb:5ZRT|refseq:NP_001291688.1|refseq:NP_001291689.1 - - - figure legend:Fig. 1B, 1C, 6D, 6E|comment:No interaction was observed between full-length C1orf123 protein and CCS.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/07/01 2019/07/01 rogid:r5pGUXbIewnEFuTqrKn78aG7N309606 rogid:rSzxgaF5mvNQbCzTTmoc6I2CBfo9606 rigid:fM+3+umvFmP9FMctgmdLLMwBI3Q false sufficient binding region:1..1-75..75 mutation disrupting interaction strength:70-70,67-67|mutation with no effect:33-33,36-36|sufficient binding region:52-160 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14618 uniprotkb:Q9NWV4 intact:EBI-11668690|uniprotkb:Q2M366|uniprotkb:Q8NEV0|ensembl:ENSP00000436318 intact:EBI-724109|ensembl:ENSP00000294360 psi-mi:ccs_human(display_long)|uniprotkb:CCS(gene name)|psi-mi:CCS(display_short)|uniprotkb:Superoxide dismutase copper chaperone(gene name synonym) psi-mi:czib_human(display_long)|uniprotkb:CZIB(gene name)|psi-mi:CZIB(display_short)|uniprotkb:C1orf123(gene name synonym)|uniprotkb:UPF0587 protein C1orf123(gene name synonym) psi-mi:"MI:0018"(two hybrid) Furukawa et al. (2017) pubmed:30260988|imex:IM-27658 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21460998|imex:IM-27658-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005116.1|ensembl:ENSG00000173992(gene)|ensembl:ENST00000533244(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045296"(cadherin binding)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036163|interpro:IPR036423|mint:O14618|rcsb pdb:1DO5|rcsb pdb:2CRL|rcsb pdb:2RSQ|rcsb pdb:6FN8|rcsb pdb:6FOL|rcsb pdb:6FON|rcsb pdb:6FP6|reactome:R-HSA-3299685 refseq:NP_060357.1|ensembl:ENSG00000162384(gene)|ensembl:ENST00000294360(transcript)|go:"GO:0008270"(zinc ion binding)|interpro:IPR008584(Protein of unknown function DUF866, eukaryotic)|rcsb pdb:5ZLQ|rcsb pdb:5ZRT|refseq:NP_001291688.1|refseq:NP_001291689.1 - - - figure legend:Fig. 1B, 1C|comment:No interaction was observed between full-length C1orf123 protein and CCS.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/07/01 2019/07/01 rogid:r5pGUXbIewnEFuTqrKn78aG7N309606 rogid:rSzxgaF5mvNQbCzTTmoc6I2CBfo9606 rigid:fM+3+umvFmP9FMctgmdLLMwBI3Q false sufficient binding region:1..1-75..75 mutation causing an interaction:67-67,70-70|mutation causing an interaction:36-36,33-33 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)