#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O43435	uniprotkb:P57055	intact:EBI-21460353|uniprotkb:C6G493|uniprotkb:C6G494|uniprotkb:O43436|uniprotkb:Q96RJ2|ensembl:ENSP00000331176	intact:EBI-12092053|ensembl:ENSP00000331734	psi-mi:tbx1_human(display_long)|uniprotkb:Testis-specific T-box protein(gene name synonym)|uniprotkb:TBX1(gene name)|psi-mi:TBX1(display_short)	psi-mi:dscr6_human(display_long)|uniprotkb:RIPPLY3(gene name)|psi-mi:RIPPLY3(display_short)|uniprotkb:DSCR6(gene name synonym)|uniprotkb:Down syndrome critical region protein 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hong et al. (2018)	pubmed:30241482|imex:IM-27129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21460443|imex:IM-27129-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005983.1|refseq:NP_542377.1|refseq:NP_542378.1|refseq:XP_006724375.1|refseq:XP_016884415.1|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001945"(lymph vessel development)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007389"(pattern specification process)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021644"(vagus nerve morphogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0035176"(social behavior)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043587"(tongue morphogenesis)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048538"(thymus development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060023"(soft palate development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060415"(muscle tissue morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0070166"(enamel mineralization)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097152"(mesenchymal cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000027"(regulation of animal organ morphogenesis)|go:"GO:2001037"(positive regulation of tongue muscle cell differentiation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:4A04|ensembl:ENSG00000184058(gene)|ensembl:ENST00000329705(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)	ensembl:ENSG00000183145(gene)|ensembl:ENST00000329553(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0060037"(pharyngeal system development)|interpro:IPR028127|refseq:NP_001304697.1|refseq:NP_001304706.1|refseq:NP_061835.1	-	-	-	figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/06/28	2019/06/28	rogid:Q1WGrfdMC/qHSVdraPeZN0nKrgo9606	rogid:/BFGHk10YjyBuWtMZ88JBrKGeME9606	rigid:zhbsfwLN8Y4wqYGWnP62fZhE4Jg	false	-	mutation decreasing interaction strength:52-52|mutation with no effect:113-113|mutation with no effect:179-179|mutation with no effect:30-30	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43435	uniprotkb:P57055	intact:EBI-21460353|uniprotkb:C6G493|uniprotkb:C6G494|uniprotkb:O43436|uniprotkb:Q96RJ2|ensembl:ENSP00000331176	intact:EBI-12092053|ensembl:ENSP00000331734	psi-mi:tbx1_human(display_long)|uniprotkb:Testis-specific T-box protein(gene name synonym)|uniprotkb:TBX1(gene name)|psi-mi:TBX1(display_short)	psi-mi:dscr6_human(display_long)|uniprotkb:RIPPLY3(gene name)|psi-mi:RIPPLY3(display_short)|uniprotkb:DSCR6(gene name synonym)|uniprotkb:Down syndrome critical region protein 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hong et al. (2018)	pubmed:30241482|imex:IM-27129	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21460459|imex:IM-27129-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005983.1|refseq:NP_542377.1|refseq:NP_542378.1|refseq:XP_006724375.1|refseq:XP_016884415.1|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001945"(lymph vessel development)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007389"(pattern specification process)|go:"GO:0007498"(mesoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021644"(vagus nerve morphogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0035176"(social behavior)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042471"(ear morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043587"(tongue morphogenesis)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048538"(thymus development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060023"(soft palate development)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060415"(muscle tissue morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0070166"(enamel mineralization)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097152"(mesenchymal cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000027"(regulation of animal organ morphogenesis)|go:"GO:2001037"(positive regulation of tongue muscle cell differentiation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:4A04|ensembl:ENSG00000184058(gene)|ensembl:ENST00000329705(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)	ensembl:ENSG00000183145(gene)|ensembl:ENST00000329553(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0060037"(pharyngeal system development)|interpro:IPR028127|refseq:NP_001304697.1|refseq:NP_001304706.1|refseq:NP_061835.1	-	-	-	figure legend:Fig. 4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/06/28	2019/06/28	rogid:Q1WGrfdMC/qHSVdraPeZN0nKrgo9606	rogid:/BFGHk10YjyBuWtMZ88JBrKGeME9606	rigid:zhbsfwLN8Y4wqYGWnP62fZhE4Jg	false	-	mutation decreasing interaction strength:52-52|mutation with no effect:113-113|mutation with no effect:179-179|mutation with no effect:30-30	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)