#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q92597	uniprotkb:P20338	intact:EBI-716486|uniprotkb:O15207|uniprotkb:Q9NYR6|uniprotkb:Q9UK29|uniprotkb:Q6IBG2|uniprotkb:B3KR80|uniprotkb:B7Z446|ensembl:ENSP00000319977|ensembl:ENSP00000404854	intact:EBI-722284|uniprotkb:Q9BQ44|uniprotkb:Q5T7P7|ensembl:ENSP00000355651	psi-mi:ndrg1_human(display_long)|uniprotkb:N-myc downstream-regulated gene 1 protein(gene name synonym)|uniprotkb:Differentiation-related gene 1 protein(gene name synonym)|uniprotkb:Reducing agents and tunicamycin-responsive protein(gene name synonym)|uniprotkb:Nickel-specific induction protein Cap43(gene name synonym)|uniprotkb:Rit42(gene name synonym)|uniprotkb:NDRG1(gene name)|psi-mi:NDRG1(display_short)|uniprotkb:CAP43(gene name synonym)|uniprotkb:DRG1(gene name synonym)|uniprotkb:RTP(gene name synonym)	psi-mi:rab4a_human(display_long)|uniprotkb:RAB4A(gene name)|psi-mi:RAB4A(display_short)|uniprotkb:RAB4(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Li et al. (2017)	pubmed:28776325|imex:IM-27321	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21991905|imex:IM-27321-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128714.1|refseq:NP_006087.2|refseq:NP_001245361.1|refseq:NP_001245362.1|ensembl:ENSG00000104419(gene)|ensembl:ENST00000323851(transcript)|ensembl:ENST00000414097(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010038"(response to metal ion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045576"(mast cell activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030693|rcsb pdb:6ZMM|reactome:R-HSA-6803205	refseq:NP_004569.2|refseq:NP_001258927.1|dip:DIP-372N|ensembl:ENSG00000168118(gene)|ensembl:ENST00000366690(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041819|mint:P20338|rcsb pdb:1YU9|rcsb pdb:1Z0K|rcsb pdb:2BMD|rcsb pdb:2BME|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8875656	go:"GO:0005737"(cytoplasm)	-	-	figure legend:Figure 3a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/08/28	2019/08/28	rogid:zeyNRbcgqPcHXkqwE42s1e9uEqI9606	rogid:D2WXh1fcXRVjoim9QiqLpNdq2Gk9606	rigid:6620rmXJ4wM+cxFhZegAA8u8qGI	false	enhanced green fluorescent protein tag:?-?|mutation with no effect:146-146|necessary binding region:148-394|mutation with no effect:234-234	mcherry fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q92597	uniprotkb:P20338	intact:EBI-716486|uniprotkb:O15207|uniprotkb:Q9NYR6|uniprotkb:Q9UK29|uniprotkb:Q6IBG2|uniprotkb:B3KR80|uniprotkb:B7Z446|ensembl:ENSP00000319977|ensembl:ENSP00000404854	intact:EBI-722284|uniprotkb:Q9BQ44|uniprotkb:Q5T7P7|ensembl:ENSP00000355651	psi-mi:ndrg1_human(display_long)|uniprotkb:N-myc downstream-regulated gene 1 protein(gene name synonym)|uniprotkb:Differentiation-related gene 1 protein(gene name synonym)|uniprotkb:Reducing agents and tunicamycin-responsive protein(gene name synonym)|uniprotkb:Nickel-specific induction protein Cap43(gene name synonym)|uniprotkb:Rit42(gene name synonym)|uniprotkb:NDRG1(gene name)|psi-mi:NDRG1(display_short)|uniprotkb:CAP43(gene name synonym)|uniprotkb:DRG1(gene name synonym)|uniprotkb:RTP(gene name synonym)	psi-mi:rab4a_human(display_long)|uniprotkb:RAB4A(gene name)|psi-mi:RAB4A(display_short)|uniprotkb:RAB4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2017)	pubmed:28776325|imex:IM-27321	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21991946|imex:IM-27321-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128714.1|refseq:NP_006087.2|refseq:NP_001245361.1|refseq:NP_001245362.1|ensembl:ENSG00000104419(gene)|ensembl:ENST00000323851(transcript)|ensembl:ENST00000414097(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010038"(response to metal ion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045576"(mast cell activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030693|rcsb pdb:6ZMM|reactome:R-HSA-6803205	refseq:NP_004569.2|refseq:NP_001258927.1|dip:DIP-372N|ensembl:ENSG00000168118(gene)|ensembl:ENST00000366690(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041819|mint:P20338|rcsb pdb:1YU9|rcsb pdb:1Z0K|rcsb pdb:2BMD|rcsb pdb:2BME|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8875656	-	-	-	figure legend:FIGURE 3b|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/08/28	2019/08/28	rogid:zeyNRbcgqPcHXkqwE42s1e9uEqI9606	rogid:D2WXh1fcXRVjoim9QiqLpNdq2Gk9606	rigid:6620rmXJ4wM+cxFhZegAA8u8qGI	false	mutation decreasing interaction strength:146-146|necessary binding region:148-394|enhanced green fluorescent protein tag:?-?|mutation with no effect:234-234	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)