#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00966	uniprotkb:Q9NVM4	intact:EBI-536842|uniprotkb:Q6LDL2|uniprotkb:Q86UZ0|uniprotkb:Q96GT4|ensembl:ENSP00000253004|ensembl:ENSP00000361469|ensembl:ENSP00000361471	intact:EBI-3215577|uniprotkb:B3KUG9|uniprotkb:Q96PV5|uniprotkb:B3KPR0|uniprotkb:B4E379|uniprotkb:Q9H9L0|ensembl:ENSP00000343103|ensembl:ENSP00000409324	psi-mi:assy_human(display_long)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:ASS1(gene name)|psi-mi:ASS1(display_short)|uniprotkb:ASS(gene name synonym)	psi-mi:anm7_human(display_long)|uniprotkb:PRMT7(gene name)|psi-mi:PRMT7(display_short)|uniprotkb:KIAA1933(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT7(gene name synonym)|uniprotkb:[Myelin basic protein]-arginine N-methyltransferase PRMT7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Verma et al. (2017)	pubmed:28587924|imex:IM-27385	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22053128|imex:IM-27385-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000041.2|refseq:NP_446464.1|ensembl:ENSG00000130707(gene)|ensembl:ENST00000352480(transcript)|ensembl:ENST00000372393(transcript)|ensembl:ENST00000372394(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0000053"(argininosuccinate metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0004055"(argininosuccinate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006953"(acute-phase response)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010043"(response to zinc ion)|refseq:XP_005272257.1|go:"GO:0010046"(response to mycotoxin)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070852"(cell body fiber)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|mint:P00966|rcsb pdb:2NZ2|reactome:R-HSA-70635|dip:DIP-34055N	refseq:NP_001171753.1|refseq:NP_061896.1|refseq:NP_001276947.1|refseq:XP_016878783.1|refseq:XP_016878784.1|ensembl:ENSG00000132600(gene)|ensembl:ENST00000339507(transcript)|ensembl:ENST00000441236(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016277"([myelin basic protein]-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|interpro:IPR014644(Protein arginine N-methyltransferase)|interpro:IPR025799|interpro:IPR029063|mint:Q9NVM4|reactome:R-HSA-3214858|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)	-	-	-	figure legend:Fig. 1b, 3a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/09/30	2019/09/26	rogid:w8QSaM4Vsa54sO6Zr4okBXJF54M9606	rogid:6pWnBdY8p2OkvDp8ry31dbthK209606	rigid:EFCF4kDvFNSW2r6yv0PQM3SffpA	false	mutation disrupting interaction strength:296-296|mutation decreasing interaction strength:360-360|mutation disrupting interaction strength:363-363	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P00966	uniprotkb:Q9NVM4	intact:EBI-536842|uniprotkb:Q6LDL2|uniprotkb:Q86UZ0|uniprotkb:Q96GT4|ensembl:ENSP00000253004|ensembl:ENSP00000361469|ensembl:ENSP00000361471	intact:EBI-3215577|uniprotkb:B3KUG9|uniprotkb:Q96PV5|uniprotkb:B3KPR0|uniprotkb:B4E379|uniprotkb:Q9H9L0|ensembl:ENSP00000343103|ensembl:ENSP00000409324	psi-mi:assy_human(display_long)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:ASS1(gene name)|psi-mi:ASS1(display_short)|uniprotkb:ASS(gene name synonym)	psi-mi:anm7_human(display_long)|uniprotkb:PRMT7(gene name)|psi-mi:PRMT7(display_short)|uniprotkb:KIAA1933(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT7(gene name synonym)|uniprotkb:[Myelin basic protein]-arginine N-methyltransferase PRMT7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Verma et al. (2017)	pubmed:28587924|imex:IM-27385	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22053141|imex:IM-27385-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000041.2|refseq:NP_446464.1|ensembl:ENSG00000130707(gene)|ensembl:ENST00000352480(transcript)|ensembl:ENST00000372393(transcript)|ensembl:ENST00000372394(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0000053"(argininosuccinate metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0004055"(argininosuccinate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006953"(acute-phase response)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010043"(response to zinc ion)|refseq:XP_005272257.1|go:"GO:0010046"(response to mycotoxin)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070852"(cell body fiber)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|mint:P00966|rcsb pdb:2NZ2|reactome:R-HSA-70635|dip:DIP-34055N	refseq:NP_001171753.1|refseq:NP_061896.1|refseq:NP_001276947.1|refseq:XP_016878783.1|refseq:XP_016878784.1|ensembl:ENSG00000132600(gene)|ensembl:ENST00000339507(transcript)|ensembl:ENST00000441236(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016277"([myelin basic protein]-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|interpro:IPR014644(Protein arginine N-methyltransferase)|interpro:IPR025799|interpro:IPR029063|mint:Q9NVM4|reactome:R-HSA-3214858|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)	-	-	-	figure legend:Fig. 1c, 3b|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2019/09/30	2019/09/26	rogid:w8QSaM4Vsa54sO6Zr4okBXJF54M9606	rogid:6pWnBdY8p2OkvDp8ry31dbthK209606	rigid:EFCF4kDvFNSW2r6yv0PQM3SffpA	false	myc tag:?-?|mutation decreasing interaction strength:296-296|mutation decreasing interaction strength:360-360|mutation decreasing interaction strength:363-363	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P00966	uniprotkb:Q9NVM4	intact:EBI-536842|uniprotkb:Q6LDL2|uniprotkb:Q86UZ0|uniprotkb:Q96GT4|ensembl:ENSP00000253004|ensembl:ENSP00000361469|ensembl:ENSP00000361471	intact:EBI-3215577|uniprotkb:B3KUG9|uniprotkb:Q96PV5|uniprotkb:B3KPR0|uniprotkb:B4E379|uniprotkb:Q9H9L0|ensembl:ENSP00000343103|ensembl:ENSP00000409324	psi-mi:assy_human(display_long)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:ASS1(gene name)|psi-mi:ASS1(display_short)|uniprotkb:ASS(gene name synonym)	psi-mi:anm7_human(display_long)|uniprotkb:PRMT7(gene name)|psi-mi:PRMT7(display_short)|uniprotkb:KIAA1933(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT7(gene name synonym)|uniprotkb:[Myelin basic protein]-arginine N-methyltransferase PRMT7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Verma et al. (2017)	pubmed:28587924|imex:IM-27385	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22053149|imex:IM-27385-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000041.2|refseq:NP_446464.1|ensembl:ENSG00000130707(gene)|ensembl:ENST00000352480(transcript)|ensembl:ENST00000372393(transcript)|ensembl:ENST00000372394(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0000053"(argininosuccinate metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0004055"(argininosuccinate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006953"(acute-phase response)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010043"(response to zinc ion)|refseq:XP_005272257.1|go:"GO:0010046"(response to mycotoxin)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070852"(cell body fiber)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|mint:P00966|rcsb pdb:2NZ2|reactome:R-HSA-70635|dip:DIP-34055N	refseq:NP_001171753.1|refseq:NP_061896.1|refseq:NP_001276947.1|refseq:XP_016878783.1|refseq:XP_016878784.1|ensembl:ENSG00000132600(gene)|ensembl:ENST00000339507(transcript)|ensembl:ENST00000441236(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016277"([myelin basic protein]-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|interpro:IPR014644(Protein arginine N-methyltransferase)|interpro:IPR025799|interpro:IPR029063|mint:Q9NVM4|reactome:R-HSA-3214858|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)	-	-	-	figure legend:Fig. 1c|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2019/09/30	2019/09/26	rogid:w8QSaM4Vsa54sO6Zr4okBXJF54M9606	rogid:6pWnBdY8p2OkvDp8ry31dbthK209606	rigid:EFCF4kDvFNSW2r6yv0PQM3SffpA	false	green fluorescent protein tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P00966	uniprotkb:Q9NVM4	intact:EBI-536842|uniprotkb:Q6LDL2|uniprotkb:Q86UZ0|uniprotkb:Q96GT4|ensembl:ENSP00000253004|ensembl:ENSP00000361469|ensembl:ENSP00000361471	intact:EBI-3215577|uniprotkb:B3KUG9|uniprotkb:Q96PV5|uniprotkb:B3KPR0|uniprotkb:B4E379|uniprotkb:Q9H9L0|ensembl:ENSP00000343103|ensembl:ENSP00000409324	psi-mi:assy_human(display_long)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:ASS1(gene name)|psi-mi:ASS1(display_short)|uniprotkb:ASS(gene name synonym)	psi-mi:anm7_human(display_long)|uniprotkb:PRMT7(gene name)|psi-mi:PRMT7(display_short)|uniprotkb:KIAA1933(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT7(gene name synonym)|uniprotkb:[Myelin basic protein]-arginine N-methyltransferase PRMT7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Verma et al. (2017)	pubmed:28587924|imex:IM-27385	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22053166|imex:IM-27385-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000041.2|refseq:NP_446464.1|ensembl:ENSG00000130707(gene)|ensembl:ENST00000352480(transcript)|ensembl:ENST00000372393(transcript)|ensembl:ENST00000372394(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0000053"(argininosuccinate metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0004055"(argininosuccinate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006953"(acute-phase response)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010043"(response to zinc ion)|refseq:XP_005272257.1|go:"GO:0010046"(response to mycotoxin)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070852"(cell body fiber)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|mint:P00966|rcsb pdb:2NZ2|reactome:R-HSA-70635|dip:DIP-34055N	refseq:NP_001171753.1|refseq:NP_061896.1|refseq:NP_001276947.1|refseq:XP_016878783.1|refseq:XP_016878784.1|ensembl:ENSG00000132600(gene)|ensembl:ENST00000339507(transcript)|ensembl:ENST00000441236(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016277"([myelin basic protein]-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|interpro:IPR014644(Protein arginine N-methyltransferase)|interpro:IPR025799|interpro:IPR029063|mint:Q9NVM4|reactome:R-HSA-3214858|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)	-	-	-	figure legend:Fig. 1f|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2019/09/30	2019/09/26	rogid:w8QSaM4Vsa54sO6Zr4okBXJF54M9606	rogid:6pWnBdY8p2OkvDp8ry31dbthK209606	rigid:EFCF4kDvFNSW2r6yv0PQM3SffpA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00966	uniprotkb:Q9NVM4	intact:EBI-536842|uniprotkb:Q6LDL2|uniprotkb:Q86UZ0|uniprotkb:Q96GT4|ensembl:ENSP00000253004|ensembl:ENSP00000361469|ensembl:ENSP00000361471	intact:EBI-3215577|uniprotkb:B3KUG9|uniprotkb:Q96PV5|uniprotkb:B3KPR0|uniprotkb:B4E379|uniprotkb:Q9H9L0|ensembl:ENSP00000343103|ensembl:ENSP00000409324	psi-mi:assy_human(display_long)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:ASS1(gene name)|psi-mi:ASS1(display_short)|uniprotkb:ASS(gene name synonym)	psi-mi:anm7_human(display_long)|uniprotkb:PRMT7(gene name)|psi-mi:PRMT7(display_short)|uniprotkb:KIAA1933(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT7(gene name synonym)|uniprotkb:[Myelin basic protein]-arginine N-methyltransferase PRMT7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Verma et al. (2017)	pubmed:28587924|imex:IM-27385	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22053171|imex:IM-27385-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000041.2|refseq:NP_446464.1|ensembl:ENSG00000130707(gene)|ensembl:ENST00000352480(transcript)|ensembl:ENST00000372393(transcript)|ensembl:ENST00000372394(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0000053"(argininosuccinate metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0004055"(argininosuccinate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006953"(acute-phase response)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010043"(response to zinc ion)|refseq:XP_005272257.1|go:"GO:0010046"(response to mycotoxin)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070852"(cell body fiber)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|mint:P00966|rcsb pdb:2NZ2|reactome:R-HSA-70635|dip:DIP-34055N	refseq:NP_001171753.1|refseq:NP_061896.1|refseq:NP_001276947.1|refseq:XP_016878783.1|refseq:XP_016878784.1|ensembl:ENSG00000132600(gene)|ensembl:ENST00000339507(transcript)|ensembl:ENST00000441236(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016277"([myelin basic protein]-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|interpro:IPR014644(Protein arginine N-methyltransferase)|interpro:IPR025799|interpro:IPR029063|mint:Q9NVM4|reactome:R-HSA-3214858|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)	-	-	-	figure legend:Fig. 1f|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2019/09/30	2019/09/26	rogid:w8QSaM4Vsa54sO6Zr4okBXJF54M9606	rogid:6pWnBdY8p2OkvDp8ry31dbthK209606	rigid:EFCF4kDvFNSW2r6yv0PQM3SffpA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P00966	uniprotkb:Q9NVM4	intact:EBI-536842|uniprotkb:Q6LDL2|uniprotkb:Q86UZ0|uniprotkb:Q96GT4|ensembl:ENSP00000253004|ensembl:ENSP00000361469|ensembl:ENSP00000361471	intact:EBI-3215577|uniprotkb:B3KUG9|uniprotkb:Q96PV5|uniprotkb:B3KPR0|uniprotkb:B4E379|uniprotkb:Q9H9L0|ensembl:ENSP00000343103|ensembl:ENSP00000409324	psi-mi:assy_human(display_long)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:ASS1(gene name)|psi-mi:ASS1(display_short)|uniprotkb:ASS(gene name synonym)	psi-mi:anm7_human(display_long)|uniprotkb:PRMT7(gene name)|psi-mi:PRMT7(display_short)|uniprotkb:KIAA1933(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT7(gene name synonym)|uniprotkb:[Myelin basic protein]-arginine N-methyltransferase PRMT7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Verma et al. (2017)	pubmed:28587924|imex:IM-27385	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22053187|imex:IM-27385-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000041.2|refseq:NP_446464.1|ensembl:ENSG00000130707(gene)|ensembl:ENST00000352480(transcript)|ensembl:ENST00000372393(transcript)|ensembl:ENST00000372394(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0000053"(argininosuccinate metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0004055"(argininosuccinate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006953"(acute-phase response)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010043"(response to zinc ion)|refseq:XP_005272257.1|go:"GO:0010046"(response to mycotoxin)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070852"(cell body fiber)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|mint:P00966|rcsb pdb:2NZ2|reactome:R-HSA-70635|dip:DIP-34055N	refseq:NP_001171753.1|refseq:NP_061896.1|refseq:NP_001276947.1|refseq:XP_016878783.1|refseq:XP_016878784.1|ensembl:ENSG00000132600(gene)|ensembl:ENST00000339507(transcript)|ensembl:ENST00000441236(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016277"([myelin basic protein]-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|interpro:IPR014644(Protein arginine N-methyltransferase)|interpro:IPR025799|interpro:IPR029063|mint:Q9NVM4|reactome:R-HSA-3214858|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)	-	-	-	figure legend:Fig. 1d|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/09/30	2019/09/26	rogid:w8QSaM4Vsa54sO6Zr4okBXJF54M9606	rogid:6pWnBdY8p2OkvDp8ry31dbthK209606	rigid:EFCF4kDvFNSW2r6yv0PQM3SffpA	false	his tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P00966	uniprotkb:Q9NVM4	intact:EBI-536842|uniprotkb:Q6LDL2|uniprotkb:Q86UZ0|uniprotkb:Q96GT4|ensembl:ENSP00000253004|ensembl:ENSP00000361469|ensembl:ENSP00000361471	intact:EBI-3215577|uniprotkb:B3KUG9|uniprotkb:Q96PV5|uniprotkb:B3KPR0|uniprotkb:B4E379|uniprotkb:Q9H9L0|ensembl:ENSP00000343103|ensembl:ENSP00000409324	psi-mi:assy_human(display_long)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:ASS1(gene name)|psi-mi:ASS1(display_short)|uniprotkb:ASS(gene name synonym)	psi-mi:anm7_human(display_long)|uniprotkb:PRMT7(gene name)|psi-mi:PRMT7(display_short)|uniprotkb:KIAA1933(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT7(gene name synonym)|uniprotkb:[Myelin basic protein]-arginine N-methyltransferase PRMT7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Verma et al. (2017)	pubmed:28587924|imex:IM-27385	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22053195|imex:IM-27385-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000041.2|refseq:NP_446464.1|ensembl:ENSG00000130707(gene)|ensembl:ENST00000352480(transcript)|ensembl:ENST00000372393(transcript)|ensembl:ENST00000372394(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0000053"(argininosuccinate metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0004055"(argininosuccinate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006953"(acute-phase response)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010043"(response to zinc ion)|refseq:XP_005272257.1|go:"GO:0010046"(response to mycotoxin)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070852"(cell body fiber)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|mint:P00966|rcsb pdb:2NZ2|reactome:R-HSA-70635|dip:DIP-34055N	refseq:NP_001171753.1|refseq:NP_061896.1|refseq:NP_001276947.1|refseq:XP_016878783.1|refseq:XP_016878784.1|ensembl:ENSG00000132600(gene)|ensembl:ENST00000339507(transcript)|ensembl:ENST00000441236(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016277"([myelin basic protein]-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|interpro:IPR014644(Protein arginine N-methyltransferase)|interpro:IPR025799|interpro:IPR029063|mint:Q9NVM4|reactome:R-HSA-3214858|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)	-	-	-	figure legend:Fig. 1d, 3c|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/09/30	2019/09/26	rogid:w8QSaM4Vsa54sO6Zr4okBXJF54M9606	rogid:6pWnBdY8p2OkvDp8ry31dbthK209606	rigid:EFCF4kDvFNSW2r6yv0PQM3SffpA	false	his tag:?-?|mutation decreasing interaction strength:296-296|mutation decreasing interaction strength:360-360|mutation disrupting interaction strength:363-363	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P00966	uniprotkb:Q9NVM4	intact:EBI-536842|uniprotkb:Q6LDL2|uniprotkb:Q86UZ0|uniprotkb:Q96GT4|ensembl:ENSP00000253004|ensembl:ENSP00000361469|ensembl:ENSP00000361471	intact:EBI-3215577|uniprotkb:B3KUG9|uniprotkb:Q96PV5|uniprotkb:B3KPR0|uniprotkb:B4E379|uniprotkb:Q9H9L0|ensembl:ENSP00000343103|ensembl:ENSP00000409324	psi-mi:assy_human(display_long)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:ASS1(gene name)|psi-mi:ASS1(display_short)|uniprotkb:ASS(gene name synonym)	psi-mi:anm7_human(display_long)|uniprotkb:PRMT7(gene name)|psi-mi:PRMT7(display_short)|uniprotkb:KIAA1933(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT7(gene name synonym)|uniprotkb:[Myelin basic protein]-arginine N-methyltransferase PRMT7(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Verma et al. (2017)	pubmed:28587924|imex:IM-27385	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22053212|imex:IM-27385-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000041.2|refseq:NP_446464.1|ensembl:ENSG00000130707(gene)|ensembl:ENST00000352480(transcript)|ensembl:ENST00000372393(transcript)|ensembl:ENST00000372394(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0000053"(argininosuccinate metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0004055"(argininosuccinate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006953"(acute-phase response)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010043"(response to zinc ion)|refseq:XP_005272257.1|go:"GO:0010046"(response to mycotoxin)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070852"(cell body fiber)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|mint:P00966|rcsb pdb:2NZ2|reactome:R-HSA-70635|dip:DIP-34055N	refseq:NP_001171753.1|refseq:NP_061896.1|refseq:NP_001276947.1|refseq:XP_016878783.1|refseq:XP_016878784.1|ensembl:ENSG00000132600(gene)|ensembl:ENST00000339507(transcript)|ensembl:ENST00000441236(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016277"([myelin basic protein]-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|interpro:IPR014644(Protein arginine N-methyltransferase)|interpro:IPR025799|interpro:IPR029063|mint:Q9NVM4|reactome:R-HSA-3214858|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)	-	-	-	figure legend:Fig. 1e|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/09/30	2019/09/26	rogid:w8QSaM4Vsa54sO6Zr4okBXJF54M9606	rogid:6pWnBdY8p2OkvDp8ry31dbthK209606	rigid:EFCF4kDvFNSW2r6yv0PQM3SffpA	false	red fluorescent protein tag:?-?	enhanced green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P00966	uniprotkb:Q9NVM4	intact:EBI-536842|uniprotkb:Q6LDL2|uniprotkb:Q86UZ0|uniprotkb:Q96GT4|ensembl:ENSP00000253004|ensembl:ENSP00000361469|ensembl:ENSP00000361471	intact:EBI-3215577|uniprotkb:B3KUG9|uniprotkb:Q96PV5|uniprotkb:B3KPR0|uniprotkb:B4E379|uniprotkb:Q9H9L0|ensembl:ENSP00000343103|ensembl:ENSP00000409324	psi-mi:assy_human(display_long)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)|uniprotkb:ASS1(gene name)|psi-mi:ASS1(display_short)|uniprotkb:ASS(gene name synonym)	psi-mi:anm7_human(display_long)|uniprotkb:PRMT7(gene name)|psi-mi:PRMT7(display_short)|uniprotkb:KIAA1933(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT7(gene name synonym)|uniprotkb:[Myelin basic protein]-arginine N-methyltransferase PRMT7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Verma et al. (2017)	pubmed:28587924|imex:IM-27385	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-22055926|imex:IM-27385-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000041.2|refseq:NP_446464.1|ensembl:ENSG00000130707(gene)|ensembl:ENST00000352480(transcript)|ensembl:ENST00000372393(transcript)|ensembl:ENST00000372394(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0000053"(argininosuccinate metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0004055"(argininosuccinate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006953"(acute-phase response)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0007494"(midgut development)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010043"(response to zinc ion)|refseq:XP_005272257.1|go:"GO:0010046"(response to mycotoxin)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070852"(cell body fiber)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|mint:P00966|rcsb pdb:2NZ2|reactome:R-HSA-70635|dip:DIP-34055N	refseq:NP_001171753.1|refseq:NP_061896.1|refseq:NP_001276947.1|refseq:XP_016878783.1|refseq:XP_016878784.1|ensembl:ENSG00000132600(gene)|ensembl:ENST00000339507(transcript)|ensembl:ENST00000441236(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016277"([myelin basic protein]-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|interpro:IPR014644(Protein arginine N-methyltransferase)|interpro:IPR025799|interpro:IPR029063|mint:Q9NVM4|reactome:R-HSA-3214858|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)	-	-	-	figure legend:na|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2019/09/30	2019/10/02	rogid:w8QSaM4Vsa54sO6Zr4okBXJF54M9606	rogid:6pWnBdY8p2OkvDp8ry31dbthK209606	rigid:EFCF4kDvFNSW2r6yv0PQM3SffpA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)