#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P75830	uniprotkb:P75831	intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597	intact:EBI-1125580|ensemblbacteria:AAC73966|ensemblbacteria:BAA35598	psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name)	psi-mi:macb_ecoli(display_long)|uniprotkb:macB(gene name)|psi-mi:macB(display_short)|uniprotkb:b0879(locus name)|uniprotkb:JW0863(locus name)|uniprotkb:ybjZ(gene name synonym)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Fitzpatrick et al. (2017)	pubmed:28504659|imex:IM-28315	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-22303317|imex:IM-28315-1|wwpdb:6NIK|emdb:3652|wwpdb:5NIL	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL	refseq:NP_415400.1|interpro:IPR003439(ABC transporter-like)|refseq:WP_000188144.1|interpro:IPR017871|interpro:IPR017911|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003838(Protein of unknown function DUF214, permase predicted)|ensemblbacteria:AAC73966(transcript)|ensemblbacteria:b0879(gene)|ensemblbacteria:BAA35598(gene)|ensemblbacteria:BAA35598(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:0005524"(ATP binding)|interpro:IPR027417|interpro:IPR025857|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5LJ8|rcsb pdb:5LJ9|rcsb pdb:5LJA	emdb:EMD-3653	-	-	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2019/11/19	2020/06/01	rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333	rogid:S7jdm+RYkJxoJnwcfp+XSv8DliQ83333	rigid:oil3CG3ljnlRFHQQUXDlTHaGWUA	false	his tag:c-c	-	6	2	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P75830	uniprotkb:P02930	intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597	intact:EBI-875614|uniprotkb:Q2M9G5|ensemblbacteria:AAC76071|ensemblbacteria:BAE77091	psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name)	psi-mi:tolc_ecoli(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:mtcB(gene name synonym)|uniprotkb:mukA(gene name synonym)|uniprotkb:refI(gene name synonym)|uniprotkb:Multidrug efflux pump subunit TolC(gene name synonym)|uniprotkb:Outer membrane factor TolC(gene name synonym)|uniprotkb:colE1-i(gene name synonym)|uniprotkb:toc(gene name synonym)|uniprotkb:weeA(gene name synonym)|uniprotkb:JW5503(locus name)|uniprotkb:b3035(locus name)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Fitzpatrick et al. (2017)	pubmed:28504659|imex:IM-28315	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-22303317|imex:IM-28315-1|wwpdb:6NIK|emdb:3652|wwpdb:5NIL	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL	refseq:NP_417507.2|refseq:WP_000735278.1|dip:DIP-11007N|ensemblbacteria:AAC76071(transcript)|ensemblbacteria:b3035(gene)|ensemblbacteria:BAE77091(gene)|ensemblbacteria:BAE77091(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0009279"(cell outer membrane)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042930"(enterobactin transport)|go:"GO:0045203"(integral component of cell outer membrane)|go:"GO:0046677"(response to antibiotic)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|interpro:IPR010130(Type I secretion outer membrane protein, TolC)|rcsb pdb:1EK9|rcsb pdb:1TQQ|rcsb pdb:2VDD|rcsb pdb:2VDE|rcsb pdb:2WMZ|rcsb pdb:2XMN|rcsb pdb:5NG5|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5O66|rcsb pdb:5V5S|rcsb pdb:6WXH|rcsb pdb:6WXI	emdb:EMD-3653	-	-	figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2019/11/19	2020/06/01	rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333	rogid:67LQDsYiAt6tDwigzlhM3Pp5+JA83333	rigid:oil3CG3ljnlRFHQQUXDlTHaGWUA	false	his tag:c-c	flag tag:c-c	6	3	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)