#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25339408|imex:IM-27624-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:5A|comment:Each sample showed a time-dependent increase in ThT fluorescence indicating incorporation of monomer into the preformed fibrils.|comment:Samples of preformed fibrils with added identical variant had a greater rate of change in ThT fluorescence compared to samples of preformed fibril with added K30D apoC-II variant.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false sufficient binding region:?-? sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25339408|imex:IM-27624-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:5A|comment:Each sample showed a time-dependent increase in ThT fluorescence indicating incorporation of monomer into the preformed fibrils.|comment:Samples of preformed fibrils with added identical variant had a greater rate of change in ThT fluorescence compared to samples of preformed fibril with added K30D apoC-II variant.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false sufficient binding region:?-? mutation decreasing interaction strength:30-30 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25339428|imex:IM-27624-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:5B|comment:Each sample showed a time-dependent increase in ThT fluorescence indicating incorporation of monomer into the preformed fibrils.|comment:Samples of preformed fibrils with added identical variant had a greater rate of change in ThT fluorescence compared to samples of preformed fibril with added K30D apoC-II variant.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false sufficient binding region:?-?|mutation:69-69 sufficient binding region:?-?|mutation:69-69 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25339428|imex:IM-27624-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:5B|comment:Each sample showed a time-dependent increase in ThT fluorescence indicating incorporation of monomer into the preformed fibrils.|comment:Samples of preformed fibrils with added identical variant had a greater rate of change in ThT fluorescence compared to samples of preformed fibril with added K30D apoC-II variant.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false sufficient binding region:?-?|mutation:69-69 mutation decreasing interaction strength:30-30|mutation:69-69 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25339447|imex:IM-27624-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:5C|comment:Each sample showed a time-dependent increase in ThT fluorescence indicating incorporation of monomer into the preformed fibrils.|comment:Samples of preformed fibrils with added identical variant had a greater rate of change in ThT fluorescence compared to samples of preformed fibril with added K30D apoC-II variant.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false sufficient binding region:?-?|mutation:30-30,69-69 sufficient binding region:?-?|mutation:69-69,30-30 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25339447|imex:IM-27624-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:5C|comment:Each sample showed a time-dependent increase in ThT fluorescence indicating incorporation of monomer into the preformed fibrils.|comment:Samples of preformed fibrils with added identical variant had a greater rate of change in ThT fluorescence compared to samples of preformed fibril with added K30D apoC-II variant.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false sufficient binding region:?-?|mutation:30-30,69-69 mutation decreasing interaction strength:30-30|mutation:69-69,30-30 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25424007|imex:IM-27624-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:1A|comment:Equimolar mixtures of K30D apoC-II with WT, D69K or KDDK all showed a time- dependent increase in ThT fluorescence suggesting successful fibril formation. The maximum change in ThT fluorescence of these mixtures was higher than that of fibrils formed by WT, D69K or KDDK alone.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/02/10 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25424007|imex:IM-27624-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:1A|comment:Equimolar mixtures of K30D apoC-II with WT, D69K or KDDK all showed a time- dependent increase in ThT fluorescence suggesting successful fibril formation. The maximum change in ThT fluorescence of these mixtures was higher than that of fibrils formed by WT, D69K or KDDK alone.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/02/10 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false - mutation increasing interaction strength:30-30 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25424020|imex:IM-27624-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:1B|comment:Equimolar mixtures of K30D apoC-II with WT, D69K or KDDK all showed a time- dependent increase in ThT fluorescence suggesting successful fibril formation. The maximum change in ThT fluorescence of these mixtures was higher than that of fibrils formed by WT, D69K or KDDK alone.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/02/10 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false mutation:69-69 mutation:69-69 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25424020|imex:IM-27624-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:1B|comment:Equimolar mixtures of K30D apoC-II with WT, D69K or KDDK all showed a time- dependent increase in ThT fluorescence suggesting successful fibril formation. The maximum change in ThT fluorescence of these mixtures was higher than that of fibrils formed by WT, D69K or KDDK alone.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/02/10 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false mutation:69-69 mutation increasing interaction strength:30-30 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25424035|imex:IM-27624-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:1C|comment:Equimolar mixtures of K30D apoC-II with WT, D69K or KDDK all showed a time- dependent increase in ThT fluorescence suggesting successful fibril formation. The maximum change in ThT fluorescence of these mixtures was higher than that of fibrils formed by WT, D69K or KDDK alone.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/02/10 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false mutation:30-30,69-69 mutation:30-30,69-69 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25424035|imex:IM-27624-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:1C|comment:Equimolar mixtures of K30D apoC-II with WT, D69K or KDDK all showed a time- dependent increase in ThT fluorescence suggesting successful fibril formation. The maximum change in ThT fluorescence of these mixtures was higher than that of fibrils formed by WT, D69K or KDDK alone.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/02/10 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:mU6H7IBM5uMLLl87aksYDX3dfWs false mutation:30-30,69-69 mutation increasing interaction strength:30-30 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25338808|imex:IM-27624-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:2A|comment:WT+K30D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:LJ3ZakvCMYqb1N3Uu+sMACRT9Ms false - mutation:30-30 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25338821|imex:IM-27624-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:2B|comment:KDDK+K30D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:LJ3ZakvCMYqb1N3Uu+sMACRT9Ms false mutation:30-30,69-69 mutation:30-30 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25338831|imex:IM-27624-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:2C|comment:D69K+K30D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:LJ3ZakvCMYqb1N3Uu+sMACRT9Ms false mutation:69-69 mutation:30-30 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1312"(aut-page) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25338842|imex:IM-27624-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:3-3|comment:D69K+K30D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:LJ3ZakvCMYqb1N3Uu+sMACRT9Ms false mutation:30-30 mutation:69-69 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1312"(aut-page) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25338863|imex:IM-27624-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:3-2|comment:WT+K30D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:LJ3ZakvCMYqb1N3Uu+sMACRT9Ms false mutation:30-30 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1312"(aut-page) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25338884|imex:IM-27624-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:3-1|comment:WT, D69K, and KDDK apoC-II show little protein in the supernatant fraction, and a distinct band in the pellet fraction, indicating that the majority of protein was incorporated into fibrils. ApoC-II variant K30D shows a strong band in the supernatant fraction and little protein in the pellet fraction, confirming that K30D apoC-II does not form fibrils.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:LJ3ZakvCMYqb1N3Uu+sMACRT9Ms false mutation disrupting interaction strength:30-30|mutation with no effect:69-69|mutation with no effect:30-30,69-69 mutation disrupting interaction strength:30-30|mutation with no effect:69-69|mutation with no effect:30-30,69-69 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1312"(aut-page) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25338905|imex:IM-27624-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:3-4|comment:KDDK+K30D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:LJ3ZakvCMYqb1N3Uu+sMACRT9Ms false mutation:30-30,69-69 mutation:30-30 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25339004|imex:IM-27624-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:4B|comment:D69K+K30D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:LJ3ZakvCMYqb1N3Uu+sMACRT9Ms false mutation:30-30 mutation:69-69 - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25338997|imex:IM-27624-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:4A|comment:WT+K30D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:LJ3ZakvCMYqb1N3Uu+sMACRT9Ms false mutation:30-30 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P02655-PRO_0000002024 uniprotkb:P02655-PRO_0000002024 intact:EBI-25338752 intact:EBI-25338752 psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:p02655-pro_0000002024(display_long)|uniprotkb:Apolipoprotein C2(gene name synonym)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym) psi-mi:"MI:1232"(aggregation assay) Todorova et al. (2017) pubmed:28229588|imex:IM-27624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25339032|imex:IM-27624-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1223594(chain-parent) intact:EBI-1223594(chain-parent) - chain-seq-start:23|chain-seq-end:101 chain-seq-start:23|chain-seq-end:101 figure legend:4C|comment:KDDK+K30D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/12/07 2020/01/08 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rogid:SWD8Xv93tIqiOHkKFE9dCSEFCC49606 rigid:LJ3ZakvCMYqb1N3Uu+sMACRT9Ms false mutation:30-30,69-69 mutation:30-30 - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)