#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q92947	uniprotkb:Q92947	intact:EBI-1236978|uniprotkb:O14719|uniprotkb:A8K2Z2|ensembl:ENSP00000222214|ensembl:ENSP00000466845	intact:EBI-1236978|uniprotkb:O14719|uniprotkb:A8K2Z2|ensembl:ENSP00000222214|ensembl:ENSP00000466845	psi-mi:gcdh_human(display_long)|uniprotkb:GCDH(gene name)|psi-mi:GCDH(display_short)	psi-mi:gcdh_human(display_long)|uniprotkb:GCDH(gene name)|psi-mi:GCDH(display_short)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Schmiesing et al. (2017)	pubmed:28062662|imex:IM-27125	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21459739|imex:IM-27125-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000150.1|refseq:NP_039663.1|ensembl:ENSG00000105607(gene)|ensembl:ENST00000222214(transcript)|ensembl:ENST00000591470(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004361"(glutaryl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006568"(tryptophan metabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:Q92947|rcsb pdb:1SIQ|rcsb pdb:1SIR|rcsb pdb:2R0M|rcsb pdb:2R0N|reactome:R-HSA-71064|go:"GO:0050660"(flavin adenine dinucleotide binding)	refseq:NP_000150.1|refseq:NP_039663.1|ensembl:ENSG00000105607(gene)|ensembl:ENST00000222214(transcript)|ensembl:ENST00000591470(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004361"(glutaryl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006568"(tryptophan metabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:Q92947|rcsb pdb:1SIQ|rcsb pdb:1SIR|rcsb pdb:2R0M|rcsb pdb:2R0N|reactome:R-HSA-71064|go:"GO:0050660"(flavin adenine dinucleotide binding)	-	-	-	figure legend:Figure S7, S8, Table 2a, 2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/06/28	2019/06/28	rogid:W192IQEAyP1SdNxhI62Fh8C2UPU9606	rogid:W192IQEAyP1SdNxhI62Fh8C2UPU9606	rigid:FywHnfIc7Ae7GK9BlQH8LfH1bKU	false	renilla luciferase protein tag:c-c|mutation increasing interaction strength:50-50|mutation increasing interaction strength:88-88|mutation increasing interaction strength:90-90|mutation increasing interaction strength:94-94|mutation increasing interaction strength:113-113|mutation decreasing interaction strength:115-115|mutation increasing interaction strength:101-101|mutation increasing interaction strength:117-117|mutation decreasing interaction strength:119-119|mutation increasing interaction strength:155-155|mutation increasing interaction strength:161-161|mutation increasing interaction strength:217-217|mutation decreasing interaction strength:227-227|mutation increasing interaction strength:244-244|mutation increasing interaction strength:263-263|mutation increasing interaction strength:278-278|mutation increasing interaction strength:355-355|mutation increasing interaction strength:248-248	yellow fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P38117	uniprotkb:Q92947	intact:EBI-1056543|uniprotkb:Q6IBH7|uniprotkb:Q71RF6|uniprotkb:Q9Y3S7|uniprotkb:B3KNY2|uniprotkb:A8K766|ensembl:ENSP00000311930	intact:EBI-1236978|uniprotkb:O14719|uniprotkb:A8K2Z2|ensembl:ENSP00000222214|ensembl:ENSP00000466845	psi-mi:etfb_human(display_long)|uniprotkb:ETFB(gene name)|psi-mi:ETFB(display_short)|uniprotkb:FP585(orf name)	psi-mi:gcdh_human(display_long)|uniprotkb:GCDH(gene name)|psi-mi:GCDH(display_short)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Schmiesing et al. (2017)	pubmed:28062662|imex:IM-27125	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21460076|imex:IM-27125-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001014763.1|refseq:NP_001976.1|dip:DIP-6162N|ensembl:ENSG00000105379(gene)|ensembl:ENST00000309244(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|interpro:IPR000049(Electron transfer flavoprotein, beta-subunit, core)|interpro:IPR012255(Electron transfer flavoprotein, beta subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR033948|rcsb pdb:1EFV|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:2A1U|reactome:R-HSA-611105|reactome:R-HSA-8876725	refseq:NP_000150.1|refseq:NP_039663.1|ensembl:ENSG00000105607(gene)|ensembl:ENST00000222214(transcript)|ensembl:ENST00000591470(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004361"(glutaryl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006568"(tryptophan metabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:Q92947|rcsb pdb:1SIQ|rcsb pdb:1SIR|rcsb pdb:2R0M|rcsb pdb:2R0N|reactome:R-HSA-71064|go:"GO:0050660"(flavin adenine dinucleotide binding)	-	-	-	figure legend:Figure S9, S10, Table 2a, 2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/06/28	2019/06/28	rogid:Fip+C+sJJhYoSZXwU/FZvabPAEY9606	rogid:W192IQEAyP1SdNxhI62Fh8C2UPU9606	rigid:Ecx7dQSAed1jvBJjrmITtHOPNtE	false	renilla luciferase protein tag:c-c	yellow fluorescent protein tag:c-c|mutation increasing interaction strength:50-50|mutation increasing interaction strength:88-88|mutation increasing interaction strength:90-90|mutation increasing interaction strength:94-94|mutation increasing interaction strength:113-113|mutation increasing interaction strength:115-115|mutation increasing interaction strength:101-101|mutation decreasing interaction strength:117-117|mutation decreasing interaction strength:119-119|mutation increasing interaction strength:155-155|mutation increasing interaction strength:161-161|mutation decreasing interaction strength:217-217|mutation increasing interaction strength:227-227|mutation increasing interaction strength:244-244|mutation increasing interaction strength:263-263|mutation increasing interaction strength:278-278|mutation increasing interaction strength:355-355|mutation increasing interaction strength:248-248	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P36957	uniprotkb:Q92947	intact:EBI-351007|uniprotkb:Q9BQ32|uniprotkb:Q7LDY7|intact:EBI-2511564|uniprotkb:B7Z5W8|uniprotkb:E7ESY5|ensembl:ENSP00000335304	intact:EBI-1236978|uniprotkb:O14719|uniprotkb:A8K2Z2|ensembl:ENSP00000222214|ensembl:ENSP00000466845	psi-mi:odo2_human(display_long)|uniprotkb:DLST(gene name)|psi-mi:DLST(display_short)|uniprotkb:DLTS(gene name synonym)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym)	psi-mi:gcdh_human(display_long)|uniprotkb:GCDH(gene name)|psi-mi:GCDH(display_short)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Schmiesing et al. (2017)	pubmed:28062662|imex:IM-27125	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21460201|imex:IM-27125-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001924.2|ensembl:ENSG00000119689(gene)|ensembl:ENST00000334220(transcript)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0034451"(centriolar satellite)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0106077"(histone succinylation)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|mint:P36957|rcsb pdb:6H05|reactome:R-HSA-389661|reactome:R-HSA-71064|reactome:R-HSA-71403	refseq:NP_000150.1|refseq:NP_039663.1|ensembl:ENSG00000105607(gene)|ensembl:ENST00000222214(transcript)|ensembl:ENST00000591470(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004361"(glutaryl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006568"(tryptophan metabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:Q92947|rcsb pdb:1SIQ|rcsb pdb:1SIR|rcsb pdb:2R0M|rcsb pdb:2R0N|reactome:R-HSA-71064|go:"GO:0050660"(flavin adenine dinucleotide binding)	-	-	-	figure legend:Figure S11, S12, Table 2a, 2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/06/28	2019/06/28	rogid:lZLUcTHB/dxXBTI/IXnSjyuVmBo9606	rogid:W192IQEAyP1SdNxhI62Fh8C2UPU9606	rigid:BQMKRoGnHqozvtM6RCtPzN1wYCg	false	renilla luciferase protein tag:c-c	yellow fluorescent protein tag:c-c|mutation increasing interaction strength:50-50|mutation increasing interaction strength:88-88|mutation increasing interaction strength:90-90|mutation increasing interaction strength:94-94|mutation decreasing interaction strength:113-113|mutation increasing interaction strength:115-115|mutation decreasing interaction strength:101-101|mutation increasing interaction strength:117-117|mutation increasing interaction strength:119-119|mutation decreasing interaction strength:155-155|mutation increasing interaction strength:161-161|mutation decreasing interaction strength:217-217|mutation decreasing interaction strength:227-227|mutation increasing interaction strength:244-244|mutation increasing interaction strength:263-263|mutation increasing interaction strength:278-278|mutation decreasing interaction strength:355-355|mutation increasing interaction strength:248-248	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)