#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O00358	uniprotkb:P19419	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0008"(array technology)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348536|imex:IM-26965-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Figure 1B|comment:Other visible spots are signals for FOXF2, FOXD1 and FOXI1 binding sites, and are likely false-positives.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/09	2019/04/24	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	rigid:C8nC2Rk/fIcUdJmK3395pGI8zIA	false	flag tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00358	uniprotkb:Q04864	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	intact:EBI-307352|uniprotkb:Q2PNZ7|uniprotkb:Q6LDY0|ensembl:ENSP00000295025|intact:EBI-11133860|uniprotkb:Q17RU2	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:rel_human(display_long)|uniprotkb:REL(gene name)|psi-mi:REL(display_short)	psi-mi:"MI:0008"(array technology)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348592|imex:IM-26965-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	refseq:NP_002899.1|ensembl:ENSG00000162924(gene)|ensembl:ENST00000295025(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034097"(response to cytokine)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030505|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|interpro:IPR042845|mint:Q04864|reactome:R-HSA-1169091|ensembl:ENSP00000295025|ensembl:ENST00000394479|ensembl:ENSP00000377989|refseq:NP_001278675.1|dip:DIP-301N	-	-	-	figure legend:Figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/09	2019/04/24	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	rogid:pcMbZU8647eKKyub9wOL93NK6VE9606	rigid:zKx3eWb2qpd4UO3GxhhKEWSoUuk	false	flag tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00358	uniprotkb:P19419	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348617|imex:IM-26965-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Figure 1C, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nthy-ori-3.1)|taxid:9606(nthy-ori-3.1 Normal human primary thyroid follicular epithelial cells)	-	2019/04/09	2019/04/25	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	rigid:C8nC2Rk/fIcUdJmK3395pGI8zIA	false	flag tag:n-n|mutation with no effect:65-65	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00358	uniprotkb:P19419	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348686|imex:IM-26965-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Figure 1F|comment:All ELK1 truncations tested could be co-precipitated with FOXE1-Flag.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nthy-ori-3.1)|taxid:9606(nthy-ori-3.1 Normal human primary thyroid follicular epithelial cells)	-	2019/04/09	2019/04/25	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	rigid:C8nC2Rk/fIcUdJmK3395pGI8zIA	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00358	uniprotkb:P19419	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348642|imex:IM-26965-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Figure 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thyroid_gland)|taxid:9606(human thyroid gland)	-	2019/04/09	2019/04/24	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	rigid:C8nC2Rk/fIcUdJmK3395pGI8zIA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O00358	uniprotkb:P19419	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0728"(gal4 vp16 complementation)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348677|imex:IM-26965-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Figure 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2019/04/09	2019/04/24	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	rigid:C8nC2Rk/fIcUdJmK3395pGI8zIA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00358	ensembl:ENSG00000164362	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	intact:EBI-21348857	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|ensembl:tert_human_gene(shortlabel)|psi-mi:ENSG00000164362(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348855|imex:IM-26965-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	refseq:NP_001180305.1(see-also)|refseq:NP_937983.2(see-also)	-	-	-	figure legend:Figure 2A|comment:"There was a 4.6-fold enrichment of FOXE1  in the same region of the TERT promoter (-151 to +11-bp relative to the TSS) that is specifically bound by ELK1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thyroid_gland)|taxid:9606(human thyroid gland)	-	2019/04/09	2019/04/25	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	-	-	false	-	sufficient binding region:?-?	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
ensembl:ENSG00000164362	uniprotkb:P19419	intact:EBI-21348857	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	uniprotkb:TERT(gene name)|psi-mi:TERT(display_short)|uniprotkb:EST2(gene name synonym)|uniprotkb:TCS1(gene name synonym)|uniprotkb:TRT(gene name synonym)|ensembl:tert_human_gene(shortlabel)|psi-mi:ENSG00000164362(display_long)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348870|imex:IM-26965-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_001180305.1(see-also)|refseq:NP_937983.2(see-also)	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Figure 2A|comment:"There was a 4.6-fold enrichment of FOXE1  in the same region of the TERT promoter (-151 to +11-bp relative to the TSS) that is specifically bound by ELK1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thyroid_gland)|taxid:9606(human thyroid gland)	-	2019/04/09	2019/04/25	-	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
uniprotkb:O00358	ensembl:ENSG00000115705	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	intact:EBI-21350074	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	uniprotkb:TPO(gene name)|psi-mi:TPO(display_short)|ensembl:pert_human_gene(shortlabel)|psi-mi:ENSG00000115705(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21350067|imex:IM-26965-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	refseq:NP_000538.3|refseq:NP_001193673.1|refseq:NP_001193674.1|refseq:NP_783650.1|refseq:NP_783652.1|refseq:NP_783653.1|refseq:XP_011508683.1	-	-	-	figure legend:Figure 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thyroid_gland)|taxid:9606(human thyroid gland)	-	2019/04/09	2019/04/26	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	-	-	false	-	sufficient binding region:?-?	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
ensembl:ENSG00000115705	uniprotkb:P19419	intact:EBI-21350074	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	uniprotkb:TPO(gene name)|psi-mi:TPO(display_short)|ensembl:pert_human_gene(shortlabel)|psi-mi:ENSG00000115705(display_long)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21350084|imex:IM-26965-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	refseq:NP_000538.3|refseq:NP_001193673.1|refseq:NP_001193674.1|refseq:NP_783650.1|refseq:NP_783652.1|refseq:NP_783653.1|refseq:XP_011508683.1	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Figure 5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-thyroid_gland)|taxid:9606(human thyroid gland)	-	2019/04/09	2019/04/26	-	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
uniprotkb:O00358	intact:EBI-21348904	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	-	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:thyroglobulin_rat_k_region_promoter_probe(display_short)|psi-mi:EBI-21348904(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348887|imex:IM-26965-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	ensembl:ENSRNOG00000006104(see-also)	-	-	-	figure legend:Figure 2B LHS|comment:Positive control|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/09	2019/04/25	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	-	-	false	flag tag:n-n	biotin tag:?-?	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P19419	intact:EBI-21348901	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	-	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:tert_human_promoter_probe(display_short)|psi-mi:EBI-21348901(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348912|imex:IM-26965-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	ensembl:ENSG00000164362(see-also)	-	-	-	figure legend:Figure 2B RHS-1, Supplementary Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/09	2019/04/25	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	-	-	false	ha tag:n-n	mutation with no effect:44-44|mutation with no effect:22-22|biotin tag:?-?	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
intact:EBI-21348901	uniprotkb:O00358	-	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	psi-mi:tert_human_promoter_probe(display_short)|psi-mi:EBI-21348901(display_long)	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348921|imex:IM-26965-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164362(see-also)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:Figure 2B RHS-2,Supplementary Figure 2|comment:"The probe was readily bound by ELK1, but unexpectedly was only shifted by FOXE1 when ELK1 was also present.  A DNA-binding mutation (p.Ala65Val)  in FOXE1 abrogated its interaction with TERT-bound ELK1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/09	2019/04/25	-	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	-	false	biotin tag:?-?|mutation decreasing interaction strength:44-44|mutation decreasing interaction strength:22-22	flag tag:n-n|mutation disrupting interaction strength:65-65	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
intact:EBI-21348901	uniprotkb:P19419	-	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	psi-mi:tert_human_promoter_probe(display_short)|psi-mi:EBI-21348901(display_long)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348921|imex:IM-26965-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164362(see-also)	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Figure 2B RHS-2,Supplementary Figure 2|comment:"The probe was readily bound by ELK1, but unexpectedly was only shifted by FOXE1 when ELK1 was also present.  A DNA-binding mutation (p.Ala65Val)  in FOXE1 abrogated its interaction with TERT-bound ELK1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/09	2019/04/25	-	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	-	false	biotin tag:?-?|mutation decreasing interaction strength:44-44|mutation decreasing interaction strength:22-22	ha tag:n-n	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
intact:EBI-21348901	uniprotkb:O00358	-	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	psi-mi:tert_human_promoter_probe(display_short)|psi-mi:EBI-21348901(display_long)	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348979|imex:IM-26965-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164362(see-also)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:Supplementary Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/09	2019/04/25	-	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	-	false	mutation disrupting interaction strength:44-44|mutation disrupting interaction strength:22-22|biotin tag:?-?	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
intact:EBI-21348901	uniprotkb:P19419	-	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	psi-mi:tert_human_promoter_probe(display_short)|psi-mi:EBI-21348901(display_long)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21348979|imex:IM-26965-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164362(see-also)	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Supplementary Figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/04/09	2019/04/25	-	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	-	false	mutation disrupting interaction strength:44-44|mutation disrupting interaction strength:22-22|biotin tag:?-?	ha tag:n-n	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O00358	uniprotkb:P19419	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21349013|imex:IM-26965-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Figure 4A|antagonist:MEK inhibitor PD98059|antagonist:MEK inhibitor U0126|comment:When all known phospho-accepting Ser/Thr  were mutated in ELK, this  mutant ELK1-HA  showed a significant reduction in its ability co-immunoprecipitate FOXE1-Flag.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw1736)|taxid:9606("Thyroid gland undifferentiated (anaplastic) carcinoma")	-	2019/04/09	2019/04/25	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	rigid:C8nC2Rk/fIcUdJmK3395pGI8zIA	false	flag tag:n-n	mutation decreasing interaction strength:353-353,361-361,368-368,383-383,389-389,417-417|ha tag:n-n|phosphorylated residue:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O00358	uniprotkb:P19419	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0728"(gal4 vp16 complementation)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21349047|imex:IM-26965-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Figure 4B|antagonist:U0126 -a MEK inhibitor|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-sw1736)|taxid:9606("Thyroid gland undifferentiated (anaplastic) carcinoma")	-	2019/04/09	2019/04/25	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	rigid:C8nC2Rk/fIcUdJmK3395pGI8zIA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O00358	uniprotkb:P19419	intact:EBI-11317834|uniprotkb:Q5T109|uniprotkb:O75765|uniprotkb:Q99526|ensembl:ENSP00000364265	intact:EBI-726632|ensembl:ENSP00000247161|ensembl:ENSP00000366182|uniprotkb:O75606|uniprotkb:O95058|uniprotkb:Q969X8|uniprotkb:Q9UJM4|uniprotkb:B2R7H4	psi-mi:foxe1_human(display_long)|uniprotkb:FKHL15(gene name synonym)|uniprotkb:FOXE2(gene name synonym)|uniprotkb:Forkhead box protein E2(gene name synonym)|uniprotkb:Forkhead-related protein FKHL15(gene name synonym)|uniprotkb:HFKH4(gene name synonym)|uniprotkb:HNF-3/fork head-like protein 5(gene name synonym)|uniprotkb:TITF2(gene name synonym)|uniprotkb:TTF2(gene name synonym)|uniprotkb:Thyroid transcription factor 2(gene name synonym)|uniprotkb:FOXE1(gene name)|psi-mi:FOXE1(display_short)	psi-mi:elk1_human(display_long)|uniprotkb:ELK1(gene name)|psi-mi:ELK1(display_short)	psi-mi:"MI:0728"(gal4 vp16 complementation)	Bullock et al. (2016)	pubmed:27852061|imex:IM-26965	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21350099|imex:IM-26965-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004464.2|ensembl:ENSG00000178919(gene)|ensembl:ENST00000375123(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016477"(cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0060022"(hard palate development)|go:"GO:0060023"(soft palate development)|go:"GO:0060465"(pharynx development)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390	ensembl:ENSG00000126767(gene)|ensembl:ENST00000247161(transcript)|ensembl:ENST00000376983(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|refseq:NP_001107595.1|refseq:NP_005220.2|refseq:NP_001244097.1|refseq:XP_016884828.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071774"(response to fibroblast growth factor)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR036388|interpro:IPR036390|mint:P19419|rcsb pdb:1DUX|rcsb pdb:5VVT|reactome:R-HSA-198753|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9634638|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010467"(gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|dip:DIP-36057N	-	-	-	figure legend:Supplementary Figure 4|comment:The FOXE1 Uniprot reference sequence used here has a Alanine polyalanine tract of 16 Alanines in length.|comment:Increasing the polyalanine tract length  had an inhibitory effect upon Gal4-FOXE1 and VP16-ELK1 stimulated promoter activity.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nthy-ori-3.1)|taxid:9606(nthy-ori-3.1 Normal human primary thyroid follicular epithelial cells)	-	2019/04/09	2019/04/26	rogid:vUbX3wu5E/7vllrK/wCcz13dY989606	rogid:fhzXfUkfVKwHJ263gkK8USP+olg9606	rigid:C8nC2Rk/fIcUdJmK3395pGI8zIA	false	mutation with no effect:164-165|mutation with no effect:164-167|mutation increasing interaction strength:164-168|mutation decreasing interaction strength:179-180	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)