#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P27467 uniprotkb:P15497 intact:EBI-2899665|ensembl:ENSMUSP00000010044 intact:EBI-22052158|uniprotkb:A5D7M9|uniprotkb:Q3SZD9|ensembl:ENSBTAP00000002914 psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym) psi-mi:apoa1_bovin(display_long)|uniprotkb:Apolipoprotein A1(gene name synonym)|uniprotkb:APOA1(gene name)|psi-mi:APOA1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-22052244|imex:IM-27760-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N refseq:NP_776667.2|ensembl:ENSBTAG00000002258(gene)|ensembl:ENSBTAT00000002914(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005543"(phospholipid binding)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0015485"(cholesterol binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0019899"(enzyme binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051180"(vitamin transport)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070508"(cholesterol import)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902995"(positive regulation of phospholipid efflux)|interpro:IPR000074(Apolipoprotein A1/A4/E) - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/09/25 2019/09/25 rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090 rogid:B0aWiIdSYPlAs3RVHq7hW6u0ths9913 rigid:0O1iWv3ytcY2zvUc8G8GVpQCQSw false tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0039"(edman degradation) uniprotkb:P27467 uniprotkb:G3MYZ3 intact:EBI-2899665|ensembl:ENSMUSP00000010044 intact:EBI-22052138|ensembl:ENSBTAP00000054782 psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym) psi-mi:afam_bovin(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-22052244|imex:IM-27760-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N refseq:NP_001179104.1|refseq:XP_015327164.1|ensembl:ENSBTAG00000047833(gene)|ensembl:ENSBTAT00000063031(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0071693"(protein transport within extracellular region)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177 - - - figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/09/25 2019/09/25 rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090 rogid:Du5Ghq4ByjsCIOBGE2cCofdCqEU9913 rigid:0O1iWv3ytcY2zvUc8G8GVpQCQSw false tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0039"(edman degradation) uniprotkb:P27467 uniprotkb:G3MYZ3 intact:EBI-2899665|ensembl:ENSMUSP00000010044 intact:EBI-22052138|ensembl:ENSBTAP00000054782 psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym) psi-mi:afam_bovin(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22055044|imex:IM-27760-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N refseq:NP_001179104.1|refseq:XP_015327164.1|ensembl:ENSBTAG00000047833(gene)|ensembl:ENSBTAT00000063031(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0071693"(protein transport within extracellular region)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177 - - - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/09/25 2019/09/30 rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090 rogid:Du5Ghq4ByjsCIOBGE2cCofdCqEU9913 rigid:zynsSes0YS+KeaJhzaNIzwfz2ho false tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P27467 uniprotkb:G3MYZ3 intact:EBI-2899665|ensembl:ENSMUSP00000010044 intact:EBI-22052138|ensembl:ENSBTAP00000054782 psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym) psi-mi:afam_bovin(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080620|imex:IM-27760-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N refseq:NP_001179104.1|refseq:XP_015327164.1|ensembl:ENSBTAG00000047833(gene)|ensembl:ENSBTAT00000063031(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0071693"(protein transport within extracellular region)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177 - - - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/09/25 2019/10/08 rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090 rogid:Du5Ghq4ByjsCIOBGE2cCofdCqEU9913 rigid:zynsSes0YS+KeaJhzaNIzwfz2ho false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P27467 uniprotkb:P43652 intact:EBI-2899665|ensembl:ENSMUSP00000010044 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym) psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080635|imex:IM-27760-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 - - - figure legend:Fig. 4|comment:Wnt3a and AFM only co-elute in the absence of detergent|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/09/25 2020/06/12 rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rigid:YKBtivJzkurrLOXRfY7EIFuD45w false tag:n-n - 1 1 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43652 uniprotkb:P04628 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 intact:EBI-21892757|uniprotkb:Q5U0N2|ensembl:ENSP00000293549 psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:wnt1_human(display_long)|uniprotkb:Proto-oncogene Int-1 homolog(gene name synonym)|uniprotkb:WNT1(gene name)|psi-mi:WNT1(display_short)|uniprotkb:INT1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080655|imex:IM-27760-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 refseq:NP_005421.1|ensembl:ENSG00000125084(gene)|ensembl:ENST00000293549(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016015"(morphogen activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021536"(diencephalon development)|go:"GO:0021551"(central nervous system morphogenesis)|go:"GO:0021588"(cerebellum formation)|go:"GO:0021797"(forebrain anterior/posterior pattern specification)|go:"GO:0022004"(midbrain-hindbrain boundary maturation during brain development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060061"(Spemann organizer formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060348"(bone development)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990403"(embryonic brain development)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009139(Wnt-1 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-381340|reactome:R-HSA-4086400|reactome:R-HSA-4641262 - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rogid:+EDXre2hHFmV+/NtN+56LCCyKCc9606 rigid:xRjmZAwkHit+4IsNKfEcOI2JuFg false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43652 uniprotkb:Q93097 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 intact:EBI-22080674|uniprotkb:O14903|uniprotkb:Q5TEH9|uniprotkb:Q5TEI2|uniprotkb:Q9HDC1|uniprotkb:Q9HDC2|ensembl:ENSP00000358698 psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:wnt2b_human(display_long)|uniprotkb:Protein Wnt-13(gene name synonym)|uniprotkb:WNT2B(gene name)|psi-mi:WNT2B(display_short)|uniprotkb:WNT13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080717|imex:IM-27760-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 refseq:NP_001278809.1|refseq:NP_004176.2|refseq:NP_078613.1|ensembl:ENSG00000134245(gene)|ensembl:ENST00000369684(transcript)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008584"(male gonad development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0021871"(forebrain regionalization)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045165"(cell fate commitment)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060492"(lung induction)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009140(Wnt-2 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-HSA-3238698|reactome:R-HSA-373080 - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rogid:eVuetIy+jSQPCR+t0ZkStyZDSdg9606 rigid:wZBcik3UbKN6REKoDf7VW6msOvI false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P56703 uniprotkb:P43652 intact:EBI-3644922|uniprotkb:Q2M237|uniprotkb:Q9H1J9|ensembl:ENSP00000225512|ensembl:ENSP00000478327|ensembl:ENSP00000480990 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 psi-mi:wnt3_human(display_long)|uniprotkb:WNT3(gene name)|psi-mi:WNT3(display_short)|uniprotkb:INT4(gene name synonym)|uniprotkb:Proto-oncogene Int-4 homolog(gene name synonym) psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080725|imex:IM-27760-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_110380.1|ensembl:ENSG00000108379(gene)|ensembl:ENSG00000277626(gene)|ensembl:ENSG00000277641(gene)|ensembl:ENST00000225512(transcript)|ensembl:ENST00000611547(transcript)|ensembl:ENST00000616347(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007276"(gamete generation)|go:"GO:0007411"(axon guidance)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0044339"(canonical Wnt signaling pathway involved in osteoblast differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060064"(Spemann organizer formation at the anterior end of the primitive streak)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060174"(limb bud formation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1905474"(canonical Wnt signaling pathway involved in stem cell proliferation)|go:"GO:1990909"(Wnt signalosome)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|rcsb pdb:6AHY|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080 ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:kf9z2nF0k139zqLaC8Ue5+qNBvs9606 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rigid:DlpgEMEV5zNJsOughuaJLyW1ScY false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43652 uniprotkb:P56704 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 intact:EBI-6173037|ensembl:ENSP00000284523|uniprotkb:Q3SY80|uniprotkb:Q969P2|uniprotkb:Q3SY79 psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:wnt3a_human(display_long)|uniprotkb:WNT3A(gene name)|psi-mi:WNT3A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080733|imex:IM-27760-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 ensembl:ENSG00000154342(gene)|ensembl:ENST00000284523(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0005576"(extracellular region)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-3772470|reactome:R-HSA-4641262|reactome:R-HSA-4641263|reactome:R-HSA-5340588|refseq:NP_149122.1|dip:DIP-58592N - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rogid:rYpTGWi5cUzJcIyzMor27nheDOE9606 rigid:+foR2AqOU/F5zawBkhvKEIbcrSQ false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43652 uniprotkb:P41221 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 intact:EBI-6594545|uniprotkb:A8K4A4|uniprotkb:Q6P278|ensembl:ENSP00000264634|ensembl:ENSP00000417310 psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:wnt5a_human(display_long)|uniprotkb:WNT5A(gene name)|psi-mi:WNT5A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080741|imex:IM-27760-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 refseq:XP_006713387.1|refseq:XP_011532389.1|refseq:XP_011532387.1|refseq:XP_011532388.1|refseq:XP_011532390.1|refseq:XP_011532391.1|refseq:NP_001243034.1|refseq:NP_003383.2|refseq:XP_016862617.1|dip:DIP-29735N|ensembl:ENSG00000114251(gene)|ensembl:ENST00000264634(transcript)|ensembl:ENST00000474267(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001756"(somitogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003283"(atrial septum development)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0003408"(optic cup formation involved in camera-type eye development)|go:"GO:0005109"(frizzled binding)|go:"GO:0005115"(receptor tyrosine kinase-like orphan receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0007411"(axon guidance)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008584"(male gonad development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036517"(chemoattraction of serotonergic neuron axon)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0036518"(chemorepulsion of dopaminergic neuron axon)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048806"(genitalia development)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048850"(hypophysis morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060067"(cervix development)|go:"GO:0060068"(vagina development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060324"(face development)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060686"(negative regulation of prostatic bud formation)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061347"(planar cell polarity pathway involved in outflow tract morphogenesis)|go:"GO:0061348"(planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:0061349"(planar cell polarity pathway involved in cardiac right atrium morphogenesis)|go:"GO:0061350"(planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:0061354"(planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:0062009"(secondary palate development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099068"(postsynapse assembly)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902379"(chemoattractant activity involved in axon guidance)|go:"GO:1902474"(positive regulation of protein localization to synapse)|go:"GO:1903827"|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1904862"(inhibitory synapse assembly)|go:"GO:1904934"(negative regulation of cell proliferation in midbrain)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1904955"(planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026538|interpro:IPR043158|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-3772470|reactome:R-HSA-4086398|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|go:"GO:1900020"(positive regulation of protein kinase C activity) - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rogid:weJx4JkAu87Y6SLhWcc7GvgHLIU9606 rigid:p4gKckOaMbV6NyGwH2LYcvwVPWc false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43652 uniprotkb:O00755 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 intact:EBI-727198|uniprotkb:Q9Y560|uniprotkb:Q96H90|ensembl:ENSP00000285018 psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:wnt7a_human(display_long)|uniprotkb:WNT7A(gene name)|psi-mi:WNT7A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080749|imex:IM-27760-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 refseq:NP_004616.2|ensembl:ENSG00000154764(gene)|ensembl:ENST00000285018(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001525"(angiogenesis)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014719"(skeletal muscle satellite cell activation)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045165"(cell fate commitment)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0062009"(secondary palate development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048864"(stem cell development)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060054"(positive regulation of epithelial cell proliferation involved in wound healing)|go:"GO:0060066"(oviduct development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099068"(postsynapse assembly)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1904891"(positive regulation of excitatory synapse assembly)|go:"GO:1905386"(positive regulation of protein localization to presynapse)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR005817(Wnt superfamily)|interpro:IPR013300(Wnt-7 protein)|interpro:IPR018161|interpro:IPR043158|rcsb pdb:4UZQ|reactome:R-HSA-3238698|reactome:R-HSA-373080|dip:DIP-61511N - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rogid:dydZ+HONRF0rd3v9Za9GTgBOlkU9606 rigid:p7Kpvl4KGi+UJZqKJCtbFDqoff8 false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43652 uniprotkb:P56706 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 intact:EBI-3913589|uniprotkb:B8A596|uniprotkb:Q96Q12|ensembl:ENSP00000341032 psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:wnt7b_human(display_long)|uniprotkb:WNT7B(gene name)|psi-mi:WNT7B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080757|imex:IM-27760-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 refseq:NP_478679.1|ensembl:ENSG00000188064(gene)|ensembl:ENST00000339464(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016332"(establishment or maintenance of polarity of embryonic epithelium)|go:"GO:0021871"(forebrain regionalization)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030324"(lung development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032536"(regulation of cell projection size)|go:"GO:0042592"(homeostatic process)|go:"GO:0044237"(cellular metabolic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048144"(fibroblast proliferation)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060482"(lobar bronchus development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060560"(developmental growth involved in morphogenesis)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072053"(renal inner medulla development)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072060"(outer medullary collecting duct development)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072236"(metanephric loop of Henle development)|interpro:IPR005817(Wnt superfamily)|interpro:IPR013300(Wnt-7 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-HSA-3238698|reactome:R-HSA-373080|go:"GO:0030182"(neuron differentiation) - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rogid:e1adNIubTXBMNKtYw+tAr+b6cJQ9606 rigid:M5oSl3+rUdgCQN2sZ2gif2PTriI false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43652 uniprotkb:Q9H1J5 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 intact:EBI-22080765|uniprotkb:Q96S51|ensembl:ENSP00000381739 psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:wnt8a_human(display_long)|uniprotkb:Protein Wnt-8d(gene name synonym)|uniprotkb:WNT8D(gene name synonym)|uniprotkb:WNT8A(gene name)|psi-mi:WNT8A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080803|imex:IM-27760-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 refseq:NP_001287867.1|refseq:NP_001287868.1|refseq:NP_490645.1|interpro:IPR005817(Wnt superfamily)|interpro:IPR013301(Wnt-8 protein)|interpro:IPR018161|interpro:IPR034312|interpro:IPR043158|rcsb pdb:7KC4|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-4641262|ensembl:ENSG00000061492(gene)|ensembl:ENST00000398754(transcript)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0014034"(neural crest cell fate commitment)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044335"(canonical Wnt signaling pathway involved in neural crest cell differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0062023"(collagen-containing extracellular matrix) - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rogid:1nGsDFVnAaPPNDSNKmRyfMWWTps9606 rigid:XjfeKgY0bV7ZGyzZ1oz93hQIGC0 false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43652 uniprotkb:O14904 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 intact:EBI-12053451|ensembl:ENSP00000272164|uniprotkb:A6NLW2|uniprotkb:Q2M2J3|uniprotkb:Q5VWU0|uniprotkb:Q96S50 psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:wnt9a_human(display_long)|uniprotkb:WNT9A(gene name)|psi-mi:WNT9A(display_short)|uniprotkb:Protein Wnt-14(gene name synonym)|uniprotkb:WNT14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080811|imex:IM-27760-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 ensembl:ENSG00000143816(gene)|ensembl:ENST00000272164(transcript)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072498"(embryonic skeletal joint development)|interpro:IPR005817(Wnt superfamily)|interpro:IPR013303(Wnt-14 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-3772470|refseq:NP_003386.1 - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rogid:YyWBjqh1NqNosniJBMeGZh8aMLg9606 rigid:QdHE1ebF8xvtB9G+JzEUO2GVfBQ false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43652 uniprotkb:O14905 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 intact:EBI-20842921|ensembl:ENSP00000290015|ensembl:ENSP00000482127|uniprotkb:Q6UXT4|uniprotkb:Q96Q09 psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:wnt9b_human(display_long)|uniprotkb:Protein Wnt-14b(gene name synonym)|uniprotkb:Protein Wnt-15(gene name synonym)|uniprotkb:WNT9B(gene name)|psi-mi:WNT9B(display_short)|uniprotkb:WNT14B(gene name synonym)|uniprotkb:WNT15(gene name synonym)|uniprotkb:UNQ6973/PRO21956(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080819|imex:IM-27760-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 ensembl:ENSG00000158955(gene)|ensembl:ENSG00000276799(gene)|ensembl:ENST00000290015(transcript)|ensembl:ENST00000613753(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003339"(regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030539"(male genitalia development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035150"(regulation of tube size)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072003"(kidney rudiment formation)|go:"GO:0072038"(mesenchymal stem cell maintenance involved in nephron morphogenesis)|go:"GO:0072044"(collecting duct development)|go:"GO:0072046"(establishment of planar polarity involved in nephron morphogenesis)|go:"GO:0072174"(metanephric tubule formation)|go:"GO:0072181"(mesonephric duct formation)|go:"GO:1902455"(negative regulation of stem cell population maintenance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1905438"(non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026535|interpro:IPR043158|reactome:R-HSA-3238698|reactome:R-HSA-373080|go:"GO:0039706"(co-receptor binding)|refseq:NP_003387.1 - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rogid:3gklX9Uf2BB+xWR8HCKFIkUGhqQ9606 rigid:WSbPXd7PB78OIVUfKRJWNy7cua8 false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43652 uniprotkb:Q9GZT5 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 intact:EBI-2799760|uniprotkb:Q9H7S8|uniprotkb:Q96TA7|uniprotkb:Q53S44|ensembl:ENSP00000258411 psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:wn10a_human(display_long)|uniprotkb:WNT10A(gene name)|psi-mi:WNT10A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080827|imex:IM-27760-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 refseq:NP_079492.2|go:"GO:0005615"(extracellular space)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014033"(neural crest cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0042476"(odontogenesis)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0043586"(tongue development)|go:"GO:0043588"(skin development)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR005817(Wnt superfamily)|interpro:IPR013302(Wnt-10 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-HSA-3238698|reactome:R-HSA-373080|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000135925(gene)|ensembl:ENST00000258411(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity) - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rogid:zGO6D9dKxST/HSkCh3bDqpZONwU9606 rigid:TJjv+9M5gcf044E3ToDsTXUGyCM false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43652 uniprotkb:O00744 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 intact:EBI-21797207|uniprotkb:B2R7A5|uniprotkb:O00747|uniprotkb:Q4VAJ4|uniprotkb:Q4VAJ5|uniprotkb:Q8WZ97|ensembl:ENSP00000301061 psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:wn10b_human(display_long)|uniprotkb:Protein Wnt-12(gene name synonym)|uniprotkb:WNT10B(gene name)|psi-mi:WNT10B(display_short)|uniprotkb:WNT12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080835|imex:IM-27760-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 refseq:NP_003385.2|ensembl:ENSG00000169884(gene)|ensembl:ENST00000301061(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014835"(myoblast differentiation involved in skeletal muscle regeneration)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048641"(regulation of skeletal muscle tissue development)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0061196"(fungiform papilla development)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR005817(Wnt superfamily)|interpro:IPR013302(Wnt-10 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-381340 - - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rogid:XAFt6Qg27YYoL2NmFa79s9KavF09606 rigid:VW7kraBASJqMYTtu+aQhQ3Jtgls false tag:n-n tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P56703 uniprotkb:P43652 intact:EBI-3644922|uniprotkb:Q2M237|uniprotkb:Q9H1J9|ensembl:ENSP00000225512|ensembl:ENSP00000478327|ensembl:ENSP00000480990 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 psi-mi:wnt3_human(display_long)|uniprotkb:WNT3(gene name)|psi-mi:WNT3(display_short)|uniprotkb:INT4(gene name synonym)|uniprotkb:Proto-oncogene Int-4 homolog(gene name synonym) psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080850|imex:IM-27760-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_110380.1|ensembl:ENSG00000108379(gene)|ensembl:ENSG00000277626(gene)|ensembl:ENSG00000277641(gene)|ensembl:ENST00000225512(transcript)|ensembl:ENST00000611547(transcript)|ensembl:ENST00000616347(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007276"(gamete generation)|go:"GO:0007411"(axon guidance)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0044339"(canonical Wnt signaling pathway involved in osteoblast differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060064"(Spemann organizer formation at the anterior end of the primitive streak)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060174"(limb bud formation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1905474"(canonical Wnt signaling pathway involved in stem cell proliferation)|go:"GO:1990909"(Wnt signalosome)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|rcsb pdb:6AHY|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080 ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 - - - figure legend:Fig. 8A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:kf9z2nF0k139zqLaC8Ue5+qNBvs9606 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rigid:DlpgEMEV5zNJsOughuaJLyW1ScY false tag:n-n tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P27467 uniprotkb:P43652 intact:EBI-2899665|ensembl:ENSMUSP00000010044 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym) psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-22080859|imex:IM-27760-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 - - - figure legend:Fig. 7A, Fig.8A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rigid:YKBtivJzkurrLOXRfY7EIFuD45w false tag:n-n tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P56703 uniprotkb:P43652 intact:EBI-3644922|uniprotkb:Q2M237|uniprotkb:Q9H1J9|ensembl:ENSP00000225512|ensembl:ENSP00000478327|ensembl:ENSP00000480990 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 psi-mi:wnt3_human(display_long)|uniprotkb:WNT3(gene name)|psi-mi:WNT3(display_short)|uniprotkb:INT4(gene name synonym)|uniprotkb:Proto-oncogene Int-4 homolog(gene name synonym) psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-22080883|imex:IM-27760-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_110380.1|ensembl:ENSG00000108379(gene)|ensembl:ENSG00000277626(gene)|ensembl:ENSG00000277641(gene)|ensembl:ENST00000225512(transcript)|ensembl:ENST00000611547(transcript)|ensembl:ENST00000616347(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007276"(gamete generation)|go:"GO:0007411"(axon guidance)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0044339"(canonical Wnt signaling pathway involved in osteoblast differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060064"(Spemann organizer formation at the anterior end of the primitive streak)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060174"(limb bud formation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1905474"(canonical Wnt signaling pathway involved in stem cell proliferation)|go:"GO:1990909"(Wnt signalosome)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|rcsb pdb:6AHY|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080 ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 - - - figure legend:Fig. 8C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:kf9z2nF0k139zqLaC8Ue5+qNBvs9606 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rigid:DlpgEMEV5zNJsOughuaJLyW1ScY false tag:n-n tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P27467 uniprotkb:P43652 intact:EBI-2899665|ensembl:ENSMUSP00000010044 intact:EBI-20737924|ensembl:ENSP00000226355|uniprotkb:A8K3E1|uniprotkb:Q32MR3|uniprotkb:Q4W5C5 psi-mi:wnt3a_mouse(display_long)|uniprotkb:Wnt3a(gene name)|psi-mi:Wnt3a(display_short)|uniprotkb:Wnt-3a(gene name synonym) psi-mi:afam_human(display_long)|uniprotkb:Alpha-albumin(gene name synonym)|uniprotkb:AFM(gene name)|psi-mi:AFM(display_short)|uniprotkb:ALB2(gene name synonym)|uniprotkb:ALBA(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Mihara et al. (2016) imex:IM-27760|pubmed:26902720 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-22080875|imex:IM-27760-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000009900(gene)|ensembl:ENSMUST00000010044(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0022008"(neurogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4641262|reactome:R-MMU-4641263|go:"GO:1901215"(negative regulation of neuron death)|refseq:NP_033548.1|dip:DIP-55954N ensembl:ENSG00000079557(gene)|ensembl:ENST00000226355(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008431"(vitamin E binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071693"(protein transport within extracellular region)|go:"GO:0072562"(blood microparticle)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|rcsb pdb:5OKL|rcsb pdb:6FAK|rcsb pdb:6RQ7|refseq:NP_001124.1 - - - figure legend:Fig. 8B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2019/09/25 2019/10/08 rogid:8qMbzAMqZA12Q/4DcX5Qea3CdSQ10090 rogid:cJyIPp4ydJJPgsQ6wCjFzCNeZwE9606 rigid:YKBtivJzkurrLOXRfY7EIFuD45w false tag:n-n tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)