#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6ZW61 uniprotkb:Q9NPJ1 intact:EBI-6128352|uniprotkb:D3DNX5|uniprotkb:Q7Z342|uniprotkb:Q7Z482|uniprotkb:Q8NAB8|ensembl:ENSP00000319062|ensembl:ENSP00000438273 intact:EBI-721319|uniprotkb:A8K7B0|uniprotkb:D3DW18|ensembl:ENSP00000246062|ensembl:ENSP00000382008|ensembl:ENSP00000498849 psi-mi:bbs12_human(display_long)|uniprotkb:BBS12(gene name)|psi-mi:BBS12(display_short)|uniprotkb:C4orf24(gene name synonym) psi-mi:mkks_human(display_long)|uniprotkb:Bardet-Biedl syndrome 6 protein(gene name synonym)|uniprotkb:MKKS(gene name)|psi-mi:MKKS(display_short)|uniprotkb:BBS6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hulleman et al. (2015) pubmed:26900326|imex:IM-27022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21404081|imex:IM-27022-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011529982.1|refseq:NP_001171478.1|refseq:NP_689831.2|refseq:XP_016863320.1|dip:DIP-60348N|ensembl:ENSG00000181004(gene)|ensembl:ENST00000314218(transcript)|ensembl:ENST00000542236(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005929"(cilium)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042755"(eating behavior)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR042984|reactome:R-HSA-5620922 refseq:NP_061336.1|refseq:NP_740754.1|dip:DIP-60349N|ensembl:ENSG00000125863(gene)|ensembl:ENST00000347364(transcript)|ensembl:ENST00000399054(transcript)|ensembl:ENST00000651692(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007286"(spermatid development)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008406"(gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014824"(artery smooth muscle contraction)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032502"(developmental process)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035176"(social behavior)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042311"(vasodilation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046907"(intracellular transport)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051216"(cartilage development)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051877"(pigment granule aggregation in cell center)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0060324"(face development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902636"(kinociliary basal body)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR028790|reactome:R-HSA-5620922 - - - figure legend:Figure 4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/05/16 2019/05/16 rogid:n1x/po4b7gFRhkpkNylETKP7fBE9606 rogid:L2xnUng1MXSDE+PQJpgcLP4T7CQ9606 rigid:TQ54BzcMcNtYK4d9AysZQxX7rb8 false myc tag:?-? flag tag:?-?|mutation decreasing interaction strength:395-395|mutation decreasing interaction strength:277-277|mutation disrupting interaction strength:57-57 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6ZW61 uniprotkb:Q9NPJ1 intact:EBI-6128352|uniprotkb:D3DNX5|uniprotkb:Q7Z342|uniprotkb:Q7Z482|uniprotkb:Q8NAB8|ensembl:ENSP00000319062|ensembl:ENSP00000438273 intact:EBI-721319|uniprotkb:A8K7B0|uniprotkb:D3DW18|ensembl:ENSP00000246062|ensembl:ENSP00000382008|ensembl:ENSP00000498849 psi-mi:bbs12_human(display_long)|uniprotkb:BBS12(gene name)|psi-mi:BBS12(display_short)|uniprotkb:C4orf24(gene name synonym) psi-mi:mkks_human(display_long)|uniprotkb:Bardet-Biedl syndrome 6 protein(gene name synonym)|uniprotkb:MKKS(gene name)|psi-mi:MKKS(display_short)|uniprotkb:BBS6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hulleman et al. (2015) pubmed:26900326|imex:IM-27022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21404108|imex:IM-27022-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011529982.1|refseq:NP_001171478.1|refseq:NP_689831.2|refseq:XP_016863320.1|dip:DIP-60348N|ensembl:ENSG00000181004(gene)|ensembl:ENST00000314218(transcript)|ensembl:ENST00000542236(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005929"(cilium)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042755"(eating behavior)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR042984|reactome:R-HSA-5620922 refseq:NP_061336.1|refseq:NP_740754.1|dip:DIP-60349N|ensembl:ENSG00000125863(gene)|ensembl:ENST00000347364(transcript)|ensembl:ENST00000399054(transcript)|ensembl:ENST00000651692(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007286"(spermatid development)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008406"(gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014824"(artery smooth muscle contraction)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032502"(developmental process)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035176"(social behavior)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042311"(vasodilation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046907"(intracellular transport)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051216"(cartilage development)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051877"(pigment granule aggregation in cell center)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0060324"(face development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902636"(kinociliary basal body)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|interpro:IPR028790|reactome:R-HSA-5620922 - - - figure legend:Figure 4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-arpe_19)|taxid:9606(Homo sapiens retinal pigment epithelial cell line ARPE-19) - 2019/05/16 2019/05/16 rogid:n1x/po4b7gFRhkpkNylETKP7fBE9606 rogid:L2xnUng1MXSDE+PQJpgcLP4T7CQ9606 rigid:TQ54BzcMcNtYK4d9AysZQxX7rb8 false myc tag:?-? flag tag:?-?|mutation decreasing interaction strength:395-395|mutation decreasing interaction strength:277-277|mutation disrupting interaction strength:57-57 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)