#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P15731 uniprotkb:P34909 intact:EBI-19735|uniprotkb:D6VQ81|ensemblfungi:YBR082C intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:ubc4_yeast(display_long)|uniprotkb:UBC4(gene name)|psi-mi:UBC4(display_short)|uniprotkb:YBR082C(locus name)|uniprotkb:YBR0745(orf name)|uniprotkb:Ubiquitin-protein ligase 4(gene name synonym)|uniprotkb:Ubiquitin carrier protein 4(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme 4(gene name synonym) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0114"(x-ray crystallography) Bhaskar et al. (2015) imex:IM-27378|pubmed:25914052 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21989211|wwpdb:5AIE|imex:IM-27378-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009638.1|sgd:S000000286|ensemblfungi:YBR082C(gene)|ensemblfungi:YBR082C_mRNA(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070628"(proteasome binding)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1QCQ|rcsb pdb:5AIE|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-9033241|reactome:R-SCE-983168|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|dip:DIP-6596N|mint:P15731 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 - crc64:8E96137D3EB20F80 crc64:8847084BD9BF48B7 figure legend:Figure 1 B&C. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2019/08/22 2019/08/22 rogid:MCFIl+wHw5tAv9OvK57xg0aZBx4559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rigid:Xq4gfpgmSEd3BddDlg4AQt3ZVew false - binding-associated region:30-83 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P34909 uniprotkb:P25655 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Bhaskar et al. (2015) imex:IM-27378|pubmed:25914052 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21989308|wwpdb:5AJD|imex:IM-27378-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 - crc64:8847084BD9BF48B7 crc64:5B2AE15BCF95E009 figure legend:Fig 2C Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2019/08/22 2019/09/23 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rigid:IiuM2qWmT0VyMAABn9jmgrhKARk false binding-associated region:418-587 binding-associated region:1348-2093 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P34909 uniprotkb:P25655 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0096"(pull down) Bhaskar et al. (2015) imex:IM-27378|pubmed:25914052 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21989390|imex:IM-27378-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 - crc64:8847084BD9BF48B7 crc64:5B2AE15BCF95E009 figure legend:Figure 2B, 3D, 3E, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/08/22 2019/09/23 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rigid:IiuM2qWmT0VyMAABn9jmgrhKARk false sufficient binding region:442-477|glutathione s tranferase tag:n-n|necessary binding region:418-477 binding-associated region:1541-2093 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P34909 uniprotkb:P06100 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-12153|uniprotkb:D6VRI6|ensemblfungi:YDL165W psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:not2_yeast(display_long)|uniprotkb:CDC36(gene name)|psi-mi:CDC36(display_short)|uniprotkb:DNA19(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:YDL165W(locus name)|uniprotkb:cell division cycle protein 36(gene name synonym) psi-mi:"MI:0096"(pull down) Bhaskar et al. (2015) imex:IM-27378|pubmed:25914052 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-21989404|imex:IM-27378-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 ensemblfungi:YDL165W(gene)|ensemblfungi:YDL165W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|refseq:NP_010116.1|sgd:S000002324|dip:DIP-590N|mint:P06100 - crc64:8847084BD9BF48B7 crc64:7D0B69657F791371 figure legend:Figure 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/08/22 2019/09/23 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:bOgpnRcqWbxkhHJg140qzPxIBJQ559292 rigid:9/KG2AHDZhg0jRVNuSDextL3Kss false binding-associated region:418-477|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:P25655 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0096"(pull down) Bhaskar et al. (2015) imex:IM-27378|pubmed:25914052 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-21989404|imex:IM-27378-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 - crc64:8847084BD9BF48B7 crc64:5B2AE15BCF95E009 figure legend:Figure 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/08/22 2019/09/23 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rigid:9/KG2AHDZhg0jRVNuSDextL3Kss false binding-associated region:418-477|glutathione s tranferase tag:n-n binding-associated region:1541-2093 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:Q12514 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:"MI:0096"(pull down) Bhaskar et al. (2015) imex:IM-27378|pubmed:25914052 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-21989404|imex:IM-27378-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 - crc64:8847084BD9BF48B7 crc64:073137119B3E92BC figure legend:Figure 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/08/22 2019/09/23 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 rigid:9/KG2AHDZhg0jRVNuSDextL3Kss false binding-associated region:418-477|glutathione s tranferase tag:n-n binding-associated region:299-560 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12514 uniprotkb:P06100 intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W intact:EBI-12153|uniprotkb:D6VRI6|ensemblfungi:YDL165W psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:not2_yeast(display_long)|uniprotkb:CDC36(gene name)|psi-mi:CDC36(display_short)|uniprotkb:DNA19(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:YDL165W(locus name)|uniprotkb:cell division cycle protein 36(gene name synonym) psi-mi:"MI:0096"(pull down) Bhaskar et al. (2015) imex:IM-27378|pubmed:25914052 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-21991045|imex:IM-27378-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 ensemblfungi:YDL165W(gene)|ensemblfungi:YDL165W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|refseq:NP_010116.1|sgd:S000002324|dip:DIP-590N|mint:P06100 - crc64:073137119B3E92BC crc64:7D0B69657F791371 figure legend:Fig 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/08/22 2019/09/23 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 rogid:bOgpnRcqWbxkhHJg140qzPxIBJQ559292 rigid:CYpWV7nd8kdT2K/V6z5kAPwktDU false glutathione s tranferase tag:n-n|binding-associated region:299-560 - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q12514 uniprotkb:P25655 intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0096"(pull down) Bhaskar et al. (2015) imex:IM-27378|pubmed:25914052 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-21991045|imex:IM-27378-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 - crc64:073137119B3E92BC crc64:5B2AE15BCF95E009 figure legend:Fig 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/08/22 2019/09/23 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rigid:CYpWV7nd8kdT2K/V6z5kAPwktDU false glutathione s tranferase tag:n-n|binding-associated region:299-560 binding-associated region:1541-2093 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P34909 uniprotkb:P25655 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0096"(pull down) Bhaskar et al. (2015) imex:IM-27378|pubmed:25914052 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-22016599|imex:IM-27378-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 - crc64:8847084BD9BF48B7 crc64:5B2AE15BCF95E009 figure legend:Figure 3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/08/22 2019/09/23 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rigid:IiuM2qWmT0VyMAABn9jmgrhKARk false glutathione s tranferase tag:n-n|binding-associated region:418-477|mutation disrupting interaction:463-464|mutation disrupting interaction:464-464,466-466 binding-associated region:1541-2093 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P34909 uniprotkb:P25655 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Bhaskar et al. (2015) imex:IM-27378|pubmed:25914052 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-21991040|wwpdb:5AJD|imex:IM-27378-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 - crc64:8847084BD9BF48B7 crc64:5B2AE15BCF95E009 figure legend:Fig S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/08/22 2019/09/23 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rigid:IiuM2qWmT0VyMAABn9jmgrhKARk false binding-associated region:418-477 binding-associated region:1348-2093 1 1 psi-mi:"MI:0427"(Identification by mass spectrometry)|psi-mi:"MI:0433"(partial identification of protein sequence) psi-mi:"MI:0427"(Identification by mass spectrometry)|psi-mi:"MI:0433"(partial identification of protein sequence)