#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P23634-6 uniprotkb:Q5VYX0 intact:EBI-1174437|ensembl:ENSP00000350310 intact:EBI-3386081|ensembl:ENSP00000332530|uniprotkb:Q9BS33|uniprotkb:Q9NUP8 psi-mi:p23634-6(display_long)|uniprotkb:hPMCA4b(isoform synonym)|uniprotkb:AIICI(isoform synonym)|uniprotkb:ATP2B4(gene name)|psi-mi:ATP2B4(display_short)|uniprotkb:ATP2B2(gene name synonym)|uniprotkb:MXRA1(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym) psi-mi:rnls_human(display_long)|uniprotkb:RNLS(gene name)|psi-mi:RNLS(display_short)|uniprotkb:C10orf59(gene name synonym)|uniprotkb:Monoamine oxidase-C(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Wang et al. (2014) pubmed:25906147|imex:IM-27666 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21463403|imex:IM-27666-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1174388(at2b4_human)|ensembl:ENSG00000058668(gene)|ensembl:ENST00000357681(transcript) ensembl:ENSG00000184719(gene)|ensembl:ENST00000331772(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0051379"(epinephrine binding)|go:"GO:0070404"(NADH binding)|go:"GO:0071871"(response to epinephrine)|go:"GO:0097621"(monoamine oxidase activity)|go:"GO:1902074"(response to salt)|interpro:IPR002937(Amine oxidase)|interpro:IPR036188|interpro:IPR040174|rcsb pdb:3QJ4|reactome:R-HSA-197264|refseq:XP_011538226.1|refseq:NP_001026879.2|refseq:NP_060833.1|refseq:XP_016871869.1 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2019/07/03 2019/07/04 rogid:D3lzxHVCN9sCMezlVDLo5opE3uo9606 rogid:2LKDMyn0OU0Y0xWGbOkhaq3pGZs9606 rigid:TjNWan60WWloesV4XCl5wGgFUSI false - sufficient binding region:220-239|biotin tag:220-220 - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23634 uniprotkb:Q5VYX0 intact:EBI-1174388|uniprotkb:Q13450|uniprotkb:Q13452|uniprotkb:Q13455|uniprotkb:Q16817|uniprotkb:Q7Z3S1|uniprotkb:B1APW6|uniprotkb:B1APW5 intact:EBI-3386081|ensembl:ENSP00000332530|uniprotkb:Q9BS33|uniprotkb:Q9NUP8 psi-mi:at2b4_human(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 1(gene name synonym)|uniprotkb:ATP2B4(gene name)|psi-mi:ATP2B4(display_short)|uniprotkb:ATP2B2(gene name synonym)|uniprotkb:MXRA1(gene name synonym) psi-mi:rnls_human(display_long)|uniprotkb:RNLS(gene name)|psi-mi:RNLS(display_short)|uniprotkb:C10orf59(gene name synonym)|uniprotkb:Monoamine oxidase-C(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Wang et al. (2014) pubmed:25906147|imex:IM-27666 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-21497560|imex:IM-27666-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001396.1|refseq:NP_001675.3|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|rcsb pdb:1CFF|rcsb pdb:2KNE|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|mint:P23634|dip:DIP-6128N ensembl:ENSG00000184719(gene)|ensembl:ENST00000331772(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0051379"(epinephrine binding)|go:"GO:0070404"(NADH binding)|go:"GO:0071871"(response to epinephrine)|go:"GO:0097621"(monoamine oxidase activity)|go:"GO:1902074"(response to salt)|interpro:IPR002937(Amine oxidase)|interpro:IPR036188|interpro:IPR040174|rcsb pdb:3QJ4|reactome:R-HSA-197264|refseq:XP_011538226.1|refseq:NP_001026879.2|refseq:NP_060833.1|refseq:XP_016871869.1 go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane) - - figure legend:Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hk2)|taxid:9606(Homo sapiens) - 2019/07/03 2019/07/09 rogid:XAjzRea7vq4vsbCVKdZRYIWvfBM9606 rogid:2LKDMyn0OU0Y0xWGbOkhaq3pGZs9606 rigid:YsHNDHewoDOj1OQo753KEI8w3X4 false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P23634 uniprotkb:Q5VYX0 intact:EBI-1174388|uniprotkb:Q13450|uniprotkb:Q13452|uniprotkb:Q13455|uniprotkb:Q16817|uniprotkb:Q7Z3S1|uniprotkb:B1APW6|uniprotkb:B1APW5 intact:EBI-3386081|ensembl:ENSP00000332530|uniprotkb:Q9BS33|uniprotkb:Q9NUP8 psi-mi:at2b4_human(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 1(gene name synonym)|uniprotkb:ATP2B4(gene name)|psi-mi:ATP2B4(display_short)|uniprotkb:ATP2B2(gene name synonym)|uniprotkb:MXRA1(gene name synonym) psi-mi:rnls_human(display_long)|uniprotkb:RNLS(gene name)|psi-mi:RNLS(display_short)|uniprotkb:C10orf59(gene name synonym)|uniprotkb:Monoamine oxidase-C(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Wang et al. (2014) pubmed:25906147|imex:IM-27666 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21913711|imex:IM-27666-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001396.1|refseq:NP_001675.3|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|rcsb pdb:1CFF|rcsb pdb:2KNE|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|mint:P23634|dip:DIP-6128N ensembl:ENSG00000184719(gene)|ensembl:ENST00000331772(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0051379"(epinephrine binding)|go:"GO:0070404"(NADH binding)|go:"GO:0071871"(response to epinephrine)|go:"GO:0097621"(monoamine oxidase activity)|go:"GO:1902074"(response to salt)|interpro:IPR002937(Amine oxidase)|interpro:IPR036188|interpro:IPR040174|rcsb pdb:3QJ4|reactome:R-HSA-197264|refseq:XP_011538226.1|refseq:NP_001026879.2|refseq:NP_060833.1|refseq:XP_016871869.1 - - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hk2)|taxid:9606(Homo sapiens) - 2019/07/03 2019/07/11 rogid:XAjzRea7vq4vsbCVKdZRYIWvfBM9606 rogid:2LKDMyn0OU0Y0xWGbOkhaq3pGZs9606 rigid:YsHNDHewoDOj1OQo753KEI8w3X4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P23634 uniprotkb:Q5VYX0 intact:EBI-1174388|uniprotkb:Q13450|uniprotkb:Q13452|uniprotkb:Q13455|uniprotkb:Q16817|uniprotkb:Q7Z3S1|uniprotkb:B1APW6|uniprotkb:B1APW5 intact:EBI-3386081|ensembl:ENSP00000332530|uniprotkb:Q9BS33|uniprotkb:Q9NUP8 psi-mi:at2b4_human(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 1(gene name synonym)|uniprotkb:ATP2B4(gene name)|psi-mi:ATP2B4(display_short)|uniprotkb:ATP2B2(gene name synonym)|uniprotkb:MXRA1(gene name synonym) psi-mi:rnls_human(display_long)|uniprotkb:RNLS(gene name)|psi-mi:RNLS(display_short)|uniprotkb:C10orf59(gene name synonym)|uniprotkb:Monoamine oxidase-C(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Wang et al. (2014) pubmed:25906147|imex:IM-27666 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-21913719|imex:IM-27666-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001396.1|refseq:NP_001675.3|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|rcsb pdb:1CFF|rcsb pdb:2KNE|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|mint:P23634|dip:DIP-6128N ensembl:ENSG00000184719(gene)|ensembl:ENST00000331772(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0051379"(epinephrine binding)|go:"GO:0070404"(NADH binding)|go:"GO:0071871"(response to epinephrine)|go:"GO:0097621"(monoamine oxidase activity)|go:"GO:1902074"(response to salt)|interpro:IPR002937(Amine oxidase)|interpro:IPR036188|interpro:IPR040174|rcsb pdb:3QJ4|reactome:R-HSA-197264|refseq:XP_011538226.1|refseq:NP_001026879.2|refseq:NP_060833.1|refseq:XP_016871869.1 - - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hk2)|taxid:9606(Homo sapiens) - 2019/07/03 2019/07/11 rogid:XAjzRea7vq4vsbCVKdZRYIWvfBM9606 rogid:2LKDMyn0OU0Y0xWGbOkhaq3pGZs9606 rigid:YsHNDHewoDOj1OQo753KEI8w3X4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)