#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8WX94-3 uniprotkb:Q8WX94-3 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Singer et al. (2014) pubmed:25082979|imex:IM-27232 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21978851|imex:IM-27232-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) - isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:Fig 1b, Suppl Fig. 2a|comment:The full length construct of NLRP7 did not show positive interaction with self-protein|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/06 2019/08/06 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rigid:azV9VohnyWNdgj9qvqGLak9E9Wg false binding-associated region:172-623|binding-associated region:502-623|binding-associated region:1-623|mutation disrupting interaction strength:398-398|mutation disrupting interaction strength:511-511|mutation disrupting interaction strength:693-693|mutation disrupting interaction strength:693-693 binding-associated region:1-623|binding-associated region:502-623 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WX94-3 uniprotkb:Q8WX94-3 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Singer et al. (2014) pubmed:25082979|imex:IM-27232 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-22080113|imex:IM-27232-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) - isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:Fig 1b, Suppl Fig. 2a|comment:The full length construct of NLRP7 did not show positive interaction with self-protein|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/08/06 2019/10/07 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rigid:azV9VohnyWNdgj9qvqGLak9E9Wg false binding-associated region:172-623|binding-associated region:502-623|binding-associated region:1-623 mutation disrupting interaction strength:511-511|binding-associated region:1-623|binding-associated region:502-623|mutation disrupting interaction strength:398-398|mutation disrupting interaction strength:693-693|mutation disrupting interaction strength:693-693 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WX94-3 uniprotkb:Q8WX94-3 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Singer et al. (2014) pubmed:25082979|imex:IM-27232 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21978901|imex:IM-27232-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) - isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:Fig 1c, 1d|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/06 2019/08/06 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rigid:azV9VohnyWNdgj9qvqGLak9E9Wg false myc tag:?-?|binding-associated region:1-623|binding-associated region:502-623 flag tag:?-?|binding-associated region:1-623|binding-associated region:502-623 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8WX94-3 uniprotkb:Q8WX94-3 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Singer et al. (2014) pubmed:25082979|imex:IM-27232 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-22051358|imex:IM-27232-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) - isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:Fig 3a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/06 2019/09/25 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rigid:azV9VohnyWNdgj9qvqGLak9E9Wg false mutation:398-398|myc tag:?-? flag tag:?-?|mutation:398-398 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8WX94-3 uniprotkb:Q8WX94-3 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Singer et al. (2014) pubmed:25082979|imex:IM-27232 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-22051382|imex:IM-27232-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) - isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:Fig 3a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/06 2019/09/25 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rigid:azV9VohnyWNdgj9qvqGLak9E9Wg false flag tag:?-?|mutation:511-511 mutation:511-511|myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8WX94-3 uniprotkb:Q8WX94-3 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Singer et al. (2014) pubmed:25082979|imex:IM-27232 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-22051404|imex:IM-27232-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) - isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:Fig 3a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/06 2019/09/25 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rigid:azV9VohnyWNdgj9qvqGLak9E9Wg false flag tag:?-?|mutation:693-693 myc tag:?-?|mutation:693-693 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8WX94-3 uniprotkb:Q8WX94-3 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 intact:EBI-21978841|ensembl:ENSP00000467123|ensembl:ENSP00000468706|ensembl:ENSP00000479459|ensembl:ENSP00000480226|ensembl:ENSP00000481395|ensembl:ENSP00000481452|ensembl:ENSP00000482194|ensembl:ENSP00000482551|ensembl:ENSP00000482887|ensembl:ENSP00000484426|ensembl:ENSP00000484808 psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:q8wx94-3(display_long)|uniprotkb:NOD12(gene name synonym)|uniprotkb:PYPAF3(gene name synonym)|uniprotkb:NALP7(gene name synonym)|uniprotkb:NLRP7(gene name)|psi-mi:NLRP7(display_short)|uniprotkb:Nucleotide-binding oligomerization domain protein 12(gene name synonym)|uniprotkb:PYRIN-containing APAF1-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Singer et al. (2014) pubmed:25082979|imex:IM-27232 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-22051426|imex:IM-27232-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) intact:EBI-22049227(isoform-parent)|ensembl:ENSG00000167634(gene)|ensembl:ENSG00000274174(gene)|ensembl:ENSG00000274571(gene)|ensembl:ENSG00000275483(gene)|ensembl:ENSG00000276804(gene)|ensembl:ENSG00000277071(gene)|ensembl:ENSG00000277179(gene)|ensembl:ENSG00000277776(gene)|ensembl:ENSG00000277786(gene)|ensembl:ENST00000588756(transcript)|ensembl:ENST00000592784(transcript)|ensembl:ENST00000610424(transcript)|ensembl:ENST00000610981(transcript)|ensembl:ENST00000615426(transcript)|ensembl:ENST00000618343(transcript)|ensembl:ENST00000618672(transcript)|ensembl:ENST00000618740(transcript)|ensembl:ENST00000620820(transcript)|ensembl:ENST00000621238(transcript)|ensembl:ENST00000622199(transcript) - isoform-comment:No experimental confirmation available. isoform-comment:No experimental confirmation available. figure legend:Fig 3a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2019/08/06 2019/09/25 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rogid:e2KhB9sS2FqZRbRejoebYOdVMxU9606 rigid:azV9VohnyWNdgj9qvqGLak9E9Wg false flag tag:?-?|mutation:693-693 myc tag:?-?|mutation:693-693 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)