#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q5T9L3	uniprotkb:P04628	intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348	intact:EBI-21892757|uniprotkb:Q5U0N2|ensembl:ENSP00000293549	psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:wnt1_human(display_long)|uniprotkb:Proto-oncogene Int-1 homolog(gene name synonym)|uniprotkb:WNT1(gene name)|psi-mi:WNT1(display_short)|uniprotkb:INT1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Najdi et al. (2012)	pubmed:22784633|imex:IM-27861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22197179|imex:IM-27861-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome)	refseq:NP_005421.1|ensembl:ENSG00000125084(gene)|ensembl:ENST00000293549(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016015"(morphogen activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021536"(diencephalon development)|go:"GO:0021551"(central nervous system morphogenesis)|go:"GO:0021588"(cerebellum formation)|go:"GO:0021797"(forebrain anterior/posterior pattern specification)|go:"GO:0022004"(midbrain-hindbrain boundary maturation during brain development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060061"(Spemann organizer formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060348"(bone development)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990403"(embryonic brain development)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009139(Wnt-1 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-381340|reactome:R-HSA-4086400|reactome:R-HSA-4641262	-	-	comment:PORCN inhibitor IWP1, inhibits palmitoylation	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/10/30	2019/11/13	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rogid:+EDXre2hHFmV+/NtN+56LCCyKCc9606	rigid:HLyIhqR0pw0/ai8fGRG02q/G69o	false	-	v5 tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T9L3	uniprotkb:P56704	intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348	intact:EBI-6173037|ensembl:ENSP00000284523|uniprotkb:Q3SY80|uniprotkb:Q969P2|uniprotkb:Q3SY79	psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:wnt3a_human(display_long)|uniprotkb:WNT3A(gene name)|psi-mi:WNT3A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Najdi et al. (2012)	pubmed:22784633|imex:IM-27861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22197185|imex:IM-27861-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome)	ensembl:ENSG00000154342(gene)|ensembl:ENST00000284523(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003136"(negative regulation of heart induction by canonical Wnt signaling pathway)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0030879"(mammary gland development)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0039706"(co-receptor binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0005576"(extracellular region)|go:"GO:0021874"(Wnt signaling pathway involved in forebrain neuroblast division)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048337"(positive regulation of mesodermal cell fate specification)|go:"GO:0048343"(paraxial mesodermal cell fate commitment)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090676"(calcium ion transmembrane transport via low voltage-gated calcium channel)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990851"(Wnt-Frizzled-LRP5/6 complex)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000081"(positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-3772470|reactome:R-HSA-4641262|reactome:R-HSA-4641263|reactome:R-HSA-5340588|refseq:NP_149122.1|dip:DIP-58592N	-	-	-	figure legend:Fig. 7|comment:PORCN inhibitor IWP1, inhibits palmitoylation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/10/30	2019/11/13	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rogid:rYpTGWi5cUzJcIyzMor27nheDOE9606	rigid:xGm11BjUxV29RgXmxGsJnayEDfA	false	-	v5 tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T9L3	uniprotkb:P41221	intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348	intact:EBI-6594545|uniprotkb:A8K4A4|uniprotkb:Q6P278|ensembl:ENSP00000264634|ensembl:ENSP00000417310	psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:wnt5a_human(display_long)|uniprotkb:WNT5A(gene name)|psi-mi:WNT5A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Najdi et al. (2012)	pubmed:22784633|imex:IM-27861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22197193|imex:IM-27861-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome)	refseq:XP_006713387.1|refseq:XP_011532389.1|refseq:XP_011532387.1|refseq:XP_011532388.1|refseq:XP_011532390.1|refseq:XP_011532391.1|refseq:NP_001243034.1|refseq:NP_003383.2|refseq:XP_016862617.1|dip:DIP-29735N|ensembl:ENSG00000114251(gene)|ensembl:ENST00000264634(transcript)|ensembl:ENST00000474267(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001756"(somitogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003283"(atrial septum development)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0003408"(optic cup formation involved in camera-type eye development)|go:"GO:0005109"(frizzled binding)|go:"GO:0005115"(receptor tyrosine kinase-like orphan receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0007411"(axon guidance)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008584"(male gonad development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036517"(chemoattraction of serotonergic neuron axon)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0036518"(chemorepulsion of dopaminergic neuron axon)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048806"(genitalia development)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048850"(hypophysis morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060067"(cervix development)|go:"GO:0060068"(vagina development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060324"(face development)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060686"(negative regulation of prostatic bud formation)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061347"(planar cell polarity pathway involved in outflow tract morphogenesis)|go:"GO:0061348"(planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:0061349"(planar cell polarity pathway involved in cardiac right atrium morphogenesis)|go:"GO:0061350"(planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:0061354"(planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:0062009"(secondary palate development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099068"(postsynapse assembly)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902379"(chemoattractant activity involved in axon guidance)|go:"GO:1902474"(positive regulation of protein localization to synapse)|go:"GO:1903827"|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1904862"(inhibitory synapse assembly)|go:"GO:1904934"(negative regulation of cell proliferation in midbrain)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1904955"(planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026538|interpro:IPR043158|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-3772470|reactome:R-HSA-4086398|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|go:"GO:1900020"(positive regulation of protein kinase C activity)	-	-	comment:PORCN inhibitor IWP1, inhibits palmitoylation	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/10/30	2019/11/13	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rogid:weJx4JkAu87Y6SLhWcc7GvgHLIU9606	rigid:sIxPDCrS8FGvrht91ee9P+0LKCA	false	-	v5 tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T9L3	uniprotkb:Q9H1J7	intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348	intact:EBI-748568|uniprotkb:Q96S49|uniprotkb:Q9BV04|uniprotkb:A8K315|uniprotkb:D3DUP9|ensembl:ENSP00000308887|ensembl:ENSP00000380379|ensembl:ENSP00000439312	psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:wnt5b_human(display_long)|uniprotkb:WNT5B(gene name)|psi-mi:WNT5B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Najdi et al. (2012)	pubmed:22784633|imex:IM-27861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22197200|imex:IM-27861-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome)	refseq:NP_110402.2|refseq:NP_116031.1|ensembl:ENSG00000111186(gene)|ensembl:ENST00000310594(transcript)|ensembl:ENST00000397196(transcript)|ensembl:ENST00000537031(transcript)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0042060"(wound healing)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1904105"(positive regulation of convergent extension involved in gastrulation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026537|interpro:IPR043158|reactome:R-HSA-3238698|reactome:R-HSA-4086400|go:"GO:0005886"(plasma membrane)	-	-	comment:PORCN inhibitor IWP1, inhibits palmitoylation	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/10/30	2019/11/13	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rogid:CkT0y69Zcn2iGL+jO47zs2jZsP89606	rigid:uATQYXV01Vt9mtjgcZV4nms2WFc	false	-	v5 tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T9L3	uniprotkb:O00755	intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348	intact:EBI-727198|uniprotkb:Q9Y560|uniprotkb:Q96H90|ensembl:ENSP00000285018	psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:wnt7a_human(display_long)|uniprotkb:WNT7A(gene name)|psi-mi:WNT7A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Najdi et al. (2012)	pubmed:22784633|imex:IM-27861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22197207|imex:IM-27861-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome)	refseq:NP_004616.2|ensembl:ENSG00000154764(gene)|ensembl:ENST00000285018(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001525"(angiogenesis)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007548"(sex differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014719"(skeletal muscle satellite cell activation)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032355"(response to estradiol)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045165"(cell fate commitment)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0062009"(secondary palate development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048864"(stem cell development)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060054"(positive regulation of epithelial cell proliferation involved in wound healing)|go:"GO:0060066"(oviduct development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099068"(postsynapse assembly)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1904891"(positive regulation of excitatory synapse assembly)|go:"GO:1905386"(positive regulation of protein localization to presynapse)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR005817(Wnt superfamily)|interpro:IPR013300(Wnt-7 protein)|interpro:IPR018161|interpro:IPR043158|rcsb pdb:4UZQ|reactome:R-HSA-3238698|reactome:R-HSA-373080|dip:DIP-61511N	-	-	comment:PORCN inhibitor IWP1, inhibits palmitoylation	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/10/30	2019/11/13	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rogid:dydZ+HONRF0rd3v9Za9GTgBOlkU9606	rigid:41pX+r23/49f3YnN8PFgnxxCzjM	false	-	v5 tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T9L3	uniprotkb:P56706	intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348	intact:EBI-3913589|uniprotkb:B8A596|uniprotkb:Q96Q12|ensembl:ENSP00000341032	psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:wnt7b_human(display_long)|uniprotkb:WNT7B(gene name)|psi-mi:WNT7B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Najdi et al. (2012)	pubmed:22784633|imex:IM-27861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22197214|imex:IM-27861-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome)	refseq:NP_478679.1|ensembl:ENSG00000188064(gene)|ensembl:ENST00000339464(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016332"(establishment or maintenance of polarity of embryonic epithelium)|go:"GO:0021871"(forebrain regionalization)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030324"(lung development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032536"(regulation of cell projection size)|go:"GO:0042592"(homeostatic process)|go:"GO:0044237"(cellular metabolic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048144"(fibroblast proliferation)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060482"(lobar bronchus development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060560"(developmental growth involved in morphogenesis)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072053"(renal inner medulla development)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072060"(outer medullary collecting duct development)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072207"(metanephric epithelium development)|go:"GO:0072236"(metanephric loop of Henle development)|interpro:IPR005817(Wnt superfamily)|interpro:IPR013300(Wnt-7 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-HSA-3238698|reactome:R-HSA-373080|go:"GO:0030182"(neuron differentiation)	-	-	comment:PORCN inhibitor IWP1, inhibits palmitoylation	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/10/30	2019/11/13	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rogid:e1adNIubTXBMNKtYw+tAr+b6cJQ9606	rigid:DTouBDeY/jehVEvatkoV3n4o4s8	false	-	v5 tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T9L3	uniprotkb:Q9H1J5	intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348	intact:EBI-22080765|uniprotkb:Q96S51|ensembl:ENSP00000381739	psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:wnt8a_human(display_long)|uniprotkb:Protein Wnt-8d(gene name synonym)|uniprotkb:WNT8D(gene name synonym)|uniprotkb:WNT8A(gene name)|psi-mi:WNT8A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Najdi et al. (2012)	pubmed:22784633|imex:IM-27861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22197221|imex:IM-27861-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome)	refseq:NP_001287867.1|refseq:NP_001287868.1|refseq:NP_490645.1|interpro:IPR005817(Wnt superfamily)|interpro:IPR013301(Wnt-8 protein)|interpro:IPR018161|interpro:IPR034312|interpro:IPR043158|rcsb pdb:7KC4|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-4641262|ensembl:ENSG00000061492(gene)|ensembl:ENST00000398754(transcript)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0014034"(neural crest cell fate commitment)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0044335"(canonical Wnt signaling pathway involved in neural crest cell differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061317"(canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:0062009"(secondary palate development)|go:"GO:0062023"(collagen-containing extracellular matrix)	-	-	comment:PORCN inhibitor IWP1, inhibits palmitoylation	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/10/30	2019/11/13	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rogid:1nGsDFVnAaPPNDSNKmRyfMWWTps9606	rigid:YUTepMTAVQqvoeGRRti9QBtIa9U	false	-	v5 tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T9L3	uniprotkb:Q93098	intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348	intact:EBI-20863616|ensembl:ENSP00000340677|uniprotkb:O00771|uniprotkb:Q5VX55|uniprotkb:Q8WYK9	psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:wnt8b_human(display_long)|uniprotkb:WNT8B(gene name)|psi-mi:WNT8B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Najdi et al. (2012)	pubmed:22784633|imex:IM-27861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22197228|imex:IM-27861-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome)	ensembl:ENSG00000075290(gene)|ensembl:ENST00000343737(transcript)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007165"(signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007399"(nervous system development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR005817(Wnt superfamily)|interpro:IPR013301(Wnt-8 protein)|interpro:IPR018161|interpro:IPR034311|interpro:IPR043158|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-4641262|refseq:NP_003384.2	-	-	comment:PORCN inhibitor IWP1, inhibits palmitoylation	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/10/30	2019/11/13	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rogid:Bb0gHK2kMmKE4XNbgn4OUW2Gy349606	rigid:73txQG8Lz9MB6F+ceKsW1H3dBik	false	-	v5 tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T9L3	uniprotkb:O14904	intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348	intact:EBI-12053451|ensembl:ENSP00000272164|uniprotkb:A6NLW2|uniprotkb:Q2M2J3|uniprotkb:Q5VWU0|uniprotkb:Q96S50	psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:wnt9a_human(display_long)|uniprotkb:WNT9A(gene name)|psi-mi:WNT9A(display_short)|uniprotkb:Protein Wnt-14(gene name synonym)|uniprotkb:WNT14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Najdi et al. (2012)	pubmed:22784633|imex:IM-27861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22197235|imex:IM-27861-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome)	ensembl:ENSG00000143816(gene)|ensembl:ENST00000272164(transcript)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072498"(embryonic skeletal joint development)|interpro:IPR005817(Wnt superfamily)|interpro:IPR013303(Wnt-14 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-HSA-201681|reactome:R-HSA-3238698|reactome:R-HSA-373080|reactome:R-HSA-3772470|refseq:NP_003386.1	-	-	comment:PORCN inhibitor IWP1, inhibits palmitoylation	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/10/30	2019/11/13	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rogid:YyWBjqh1NqNosniJBMeGZh8aMLg9606	rigid:W/F5bk6pK7Bve0L5JcIxwf90R1Q	false	-	v5 tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T9L3	uniprotkb:O14905	intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348	intact:EBI-20842921|ensembl:ENSP00000290015|ensembl:ENSP00000482127|uniprotkb:Q6UXT4|uniprotkb:Q96Q09	psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name)	psi-mi:wnt9b_human(display_long)|uniprotkb:Protein Wnt-14b(gene name synonym)|uniprotkb:Protein Wnt-15(gene name synonym)|uniprotkb:WNT9B(gene name)|psi-mi:WNT9B(display_short)|uniprotkb:WNT14B(gene name synonym)|uniprotkb:WNT15(gene name synonym)|uniprotkb:UNQ6973/PRO21956(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Najdi et al. (2012)	pubmed:22784633|imex:IM-27861	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22197242|imex:IM-27861-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome)	ensembl:ENSG00000158955(gene)|ensembl:ENSG00000276799(gene)|ensembl:ENST00000290015(transcript)|ensembl:ENST00000613753(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003339"(regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009786"(regulation of asymmetric cell division)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030539"(male genitalia development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035150"(regulation of tube size)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072003"(kidney rudiment formation)|go:"GO:0072038"(mesenchymal stem cell maintenance involved in nephron morphogenesis)|go:"GO:0072044"(collecting duct development)|go:"GO:0072046"(establishment of planar polarity involved in nephron morphogenesis)|go:"GO:0072174"(metanephric tubule formation)|go:"GO:0072181"(mesonephric duct formation)|go:"GO:1902455"(negative regulation of stem cell population maintenance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1905438"(non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026535|interpro:IPR043158|reactome:R-HSA-3238698|reactome:R-HSA-373080|go:"GO:0039706"(co-receptor binding)|refseq:NP_003387.1	-	-	comment:PORCN inhibitor IWP1, inhibits palmitoylation	figure legend:Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2019/10/30	2019/11/13	rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606	rogid:3gklX9Uf2BB+xWR8HCKFIkUGhqQ9606	rigid:5ULjCevrdx/d9ebyZtKvn6iNYhk	false	-	v5 tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)