#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9U320	uniprotkb:Q18321	intact:EBI-21986821|ensemblmetazoa:Y105C5A.23.1	intact:EBI-21986801|ensemblmetazoa:C30B5.5.1	psi-mi:daf38_caeel(display_long)|uniprotkb:daf-38(gene name)|psi-mi:daf-38(display_short)|uniprotkb:Abnormal dauer formation protein 38(gene name synonym)|uniprotkb:Y105C5A.23(orf name)	psi-mi:daf37_caeel(display_long)|uniprotkb:daf-37(gene name)|psi-mi:daf-37(display_short)|uniprotkb:Abnormal dauer formation protein 37(gene name synonym)|uniprotkb:C30B5.5(orf name)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Park et al. (2012)	pubmed:22665789|imex:IM-27761	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22091821|imex:IM-27761-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|refseq:NP_502887.1|wormbase:Y105C5A.23|ensemblmetazoa:WBGene00013642(gene)|ensemblmetazoa:Y105C5A.23.1(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1904066"(G protein-coupled receptor signaling pathway involved in dauer larval development)	refseq:NP_001309490.1|wormbase:C30B5.5|interpro:IPR019427|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|ensemblmetazoa:C30B5.5.1(transcript)|ensemblmetazoa:WBGene00016246(gene)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097730"(non-motile cilium)|go:"GO:1904066"(G protein-coupled receptor signaling pathway involved in dauer larval development)|go:"GO:1904067"(ascr#2 binding)|go:"GO:1904068"(G protein-coupled receptor signaling pathway involved in social behavior)	-	-	-	figure legend:Fig. 6A, 6B, Supp. Table 2|agonist:"ascr#2 (CHEBI:78812)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2019/09/30	2019/10/17	rogid:7aDY1yrse8/XY0XOdLEHzrQrBU06239	rogid:4BgOC2e3bWFRn54i9jlRwg9CDWU6239	rigid:Qg9uhsJ/OmSrombzEiYTpt0p6HU	false	ha tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q18321	uniprotkb:Q18321	intact:EBI-21986801|ensemblmetazoa:C30B5.5.1	intact:EBI-21986801|ensemblmetazoa:C30B5.5.1	psi-mi:daf37_caeel(display_long)|uniprotkb:daf-37(gene name)|psi-mi:daf-37(display_short)|uniprotkb:Abnormal dauer formation protein 37(gene name synonym)|uniprotkb:C30B5.5(orf name)	psi-mi:daf37_caeel(display_long)|uniprotkb:daf-37(gene name)|psi-mi:daf-37(display_short)|uniprotkb:Abnormal dauer formation protein 37(gene name synonym)|uniprotkb:C30B5.5(orf name)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Park et al. (2012)	pubmed:22665789|imex:IM-27761	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22091858|imex:IM-27761-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001309490.1|wormbase:C30B5.5|interpro:IPR019427|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|ensemblmetazoa:C30B5.5.1(transcript)|ensemblmetazoa:WBGene00016246(gene)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097730"(non-motile cilium)|go:"GO:1904066"(G protein-coupled receptor signaling pathway involved in dauer larval development)|go:"GO:1904067"(ascr#2 binding)|go:"GO:1904068"(G protein-coupled receptor signaling pathway involved in social behavior)	refseq:NP_001309490.1|wormbase:C30B5.5|interpro:IPR019427|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|ensemblmetazoa:C30B5.5.1(transcript)|ensemblmetazoa:WBGene00016246(gene)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097730"(non-motile cilium)|go:"GO:1904066"(G protein-coupled receptor signaling pathway involved in dauer larval development)|go:"GO:1904067"(ascr#2 binding)|go:"GO:1904068"(G protein-coupled receptor signaling pathway involved in social behavior)	-	-	-	figure legend:Supp. Table 2|agonist:"(CHEBI:78812) ascr#2"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2019/09/30	2019/10/17	rogid:4BgOC2e3bWFRn54i9jlRwg9CDWU6239	rogid:4BgOC2e3bWFRn54i9jlRwg9CDWU6239	rigid:wE/EbVzuuoqY/NzO6PzvJYDhzVc	false	myc tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
chebi:"CHEBI:78812"	uniprotkb:Q18321	intact:EBI-22091899	intact:EBI-21986801|ensemblmetazoa:C30B5.5.1	psi-mi:ascr#2(display_short)|psi-mi:"CHEBI:78812"(display_long)|intact:"(-)-5R-(3'R,5'R-dihydroxy-6'S-methyl-(2H)-tetrahydropyran-2'-yloxy)-2-hexanone"(synonym)|intact:ascaroside C6(synonym)|intact:daumone-2(synonym)|intact:"(2R)-5-oxohexan-2-yl 3,6-dideoxy-alpha-L-arabino-hexopyranoside"(iupac name)	psi-mi:daf37_caeel(display_long)|uniprotkb:daf-37(gene name)|psi-mi:daf-37(display_short)|uniprotkb:Abnormal dauer formation protein 37(gene name synonym)|uniprotkb:C30B5.5(orf name)	psi-mi:"MI:0905"(amplified luminescent proximity homogeneous assay)	Park et al. (2012)	pubmed:22665789|imex:IM-27761	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22091884|imex:IM-27761-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001309490.1|wormbase:C30B5.5|interpro:IPR019427|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|ensemblmetazoa:C30B5.5.1(transcript)|ensemblmetazoa:WBGene00016246(gene)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097730"(non-motile cilium)|go:"GO:1904066"(G protein-coupled receptor signaling pathway involved in dauer larval development)|go:"GO:1904067"(ascr#2 binding)|go:"GO:1904068"(G protein-coupled receptor signaling pathway involved in social behavior)	-	-	-	figure legend:Fig. 3A, 3B, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/09/30	2020/03/16	-	rogid:4BgOC2e3bWFRn54i9jlRwg9CDWU6239	-	false	biotin tag:?-?	rho tag:c-c	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q9U320	uniprotkb:Q18321	intact:EBI-21986821|ensemblmetazoa:Y105C5A.23.1	intact:EBI-21986801|ensemblmetazoa:C30B5.5.1	psi-mi:daf38_caeel(display_long)|uniprotkb:daf-38(gene name)|psi-mi:daf-38(display_short)|uniprotkb:Abnormal dauer formation protein 38(gene name synonym)|uniprotkb:Y105C5A.23(orf name)	psi-mi:daf37_caeel(display_long)|uniprotkb:daf-37(gene name)|psi-mi:daf-37(display_short)|uniprotkb:Abnormal dauer formation protein 37(gene name synonym)|uniprotkb:C30B5.5(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Park et al. (2012)	pubmed:22665789|imex:IM-27761	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-22091913|imex:IM-27761-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|refseq:NP_502887.1|wormbase:Y105C5A.23|ensemblmetazoa:WBGene00013642(gene)|ensemblmetazoa:Y105C5A.23.1(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1904066"(G protein-coupled receptor signaling pathway involved in dauer larval development)	refseq:NP_001309490.1|wormbase:C30B5.5|interpro:IPR019427|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|ensemblmetazoa:C30B5.5.1(transcript)|ensemblmetazoa:WBGene00016246(gene)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097730"(non-motile cilium)|go:"GO:1904066"(G protein-coupled receptor signaling pathway involved in dauer larval development)|go:"GO:1904067"(ascr#2 binding)|go:"GO:1904068"(G protein-coupled receptor signaling pathway involved in social behavior)	-	-	-	figure legend:Supp. Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2019/09/30	2019/10/17	rogid:7aDY1yrse8/XY0XOdLEHzrQrBU06239	rogid:4BgOC2e3bWFRn54i9jlRwg9CDWU6239	rigid:Qg9uhsJ/OmSrombzEiYTpt0p6HU	false	ha tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)