#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8CHK4 uniprotkb:O88495 intact:EBI-1169948|uniprotkb:Q8CGZ3|uniprotkb:Q8CGZ4|uniprotkb:Q8VIH0|uniprotkb:A1L394|ensembl:ENSMUSP00000109271 intact:EBI-21227860|uniprotkb:Q3V1S8|ensembl:ENSMUSP00000064608 psi-mi:kat5_mouse(display_long)|uniprotkb:Kat5(gene name)|psi-mi:Kat5(display_short)|uniprotkb:Htatip(gene name synonym)|uniprotkb:Tip60(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym) psi-mi:mtr1l_mouse(display_long)|uniprotkb:G protein-coupled receptor 50(gene name synonym)|uniprotkb:H9(gene name synonym)|uniprotkb:Gpr50(gene name)|psi-mi:Gpr50(display_short) psi-mi:"MI:0018"(two hybrid) Li et al. (2010) pubmed:21858214|imex:IM-26972 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21227879|imex:IM-26972-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186176.1|refseq:NP_001186177.1|refseq:NP_848752.1|ensembl:ENSMUST00000113641(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|ensembl:ENSMUSG00000024926(gene)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|mint:Q8CHK4|reactome:R-MMU-2559586|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693548|reactome:R-MMU-5693565|reactome:R-MMU-5693568|reactome:R-MMU-5693571|reactome:R-MMU-5693579|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-6804756|reactome:R-MMU-69473|reactome:R-MMU-9018519 refseq:NP_034470.1|refseq:NP_001295430.1|ensembl:ENSMUSG00000056380(gene)|ensembl:ENSMUST00000070449(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002280(Melatonin-related receptor type 1X)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/03/01 2019/03/01 rogid:HmCuP1tKkN1mA5x6VY8LlnwSfwY10090 rogid:4OuzkWmEI6nBCumKxkfBrcN3FGs10090 rigid:NXDg0OBSeDkaxrVdGOCrkSNeXUE false - sufficient binding region:303-591 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8K129 uniprotkb:O88495 intact:EBI-21227903|ensembl:ENSMUSP00000057115 intact:EBI-21227860|uniprotkb:Q3V1S8|ensembl:ENSMUSP00000064608 psi-mi:ctxn1_mouse(display_long)|uniprotkb:Ctxn1(gene name)|psi-mi:Ctxn1(display_short)|uniprotkb:Ctxn(gene name synonym) psi-mi:mtr1l_mouse(display_long)|uniprotkb:G protein-coupled receptor 50(gene name synonym)|uniprotkb:H9(gene name synonym)|uniprotkb:Gpr50(gene name)|psi-mi:Gpr50(display_short) psi-mi:"MI:0018"(two hybrid) Li et al. (2010) pubmed:21858214|imex:IM-26972 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21227898|imex:IM-26972-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_899138.1|ensembl:ENSMUSG00000048644(gene)|ensembl:ENSMUST00000053252(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR020066 refseq:NP_034470.1|refseq:NP_001295430.1|ensembl:ENSMUSG00000056380(gene)|ensembl:ENSMUST00000070449(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002280(Melatonin-related receptor type 1X)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/03/01 2019/03/01 rogid:Nr7xBfIIz58oxcLIeHv2zzfJbPQ10090 rogid:4OuzkWmEI6nBCumKxkfBrcN3FGs10090 rigid:s4rtv+H6UP+PzzPVXV+1/+V791A false - sufficient binding region:303-591 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9D8U8 uniprotkb:O88495 intact:EBI-643385|uniprotkb:Q543N9|ensembl:ENSMUSP00000028909|ensembl:ENSMUSP00000105657 intact:EBI-21227860|uniprotkb:Q3V1S8|ensembl:ENSMUSP00000064608 psi-mi:snx5_mouse(display_long)|uniprotkb:Snx5(gene name)|psi-mi:Snx5(display_short) psi-mi:mtr1l_mouse(display_long)|uniprotkb:G protein-coupled receptor 50(gene name synonym)|uniprotkb:H9(gene name synonym)|uniprotkb:Gpr50(gene name)|psi-mi:Gpr50(display_short) psi-mi:"MI:0018"(two hybrid) Li et al. (2010) pubmed:21858214|imex:IM-26972 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21227917|imex:IM-26972-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186117.1|refseq:NP_077187.1|ensembl:ENSMUST00000110030(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0030904"(retromer complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070685"(macropinocytic cup)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097422"(tubular endosome)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|mint:Q9D8U8|rcsb pdb:5TP1|reactome:R-MMU-432722|ensembl:ENSMUST00000028909(transcript)|ensembl:ENSMUSG00000027423(gene) refseq:NP_034470.1|refseq:NP_001295430.1|ensembl:ENSMUSG00000056380(gene)|ensembl:ENSMUST00000070449(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002280(Melatonin-related receptor type 1X)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/03/01 2019/03/01 rogid:fQ84XvM7jLdmmQr00Afs3oaAUBI10090 rogid:4OuzkWmEI6nBCumKxkfBrcN3FGs10090 rigid:c3zIWc/tIB7anMx+7BtIjd8Kc94 false - sufficient binding region:303-591 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6P8X1 uniprotkb:O88495 intact:EBI-8393689|uniprotkb:Q9CZ03|intact:MINT-2634295|intact:MINT-4126065|ensembl:ENSMUSP00000005798 intact:EBI-21227860|uniprotkb:Q3V1S8|ensembl:ENSMUSP00000064608 psi-mi:snx6_mouse(display_long)|uniprotkb:Snx6(gene name)|psi-mi:Snx6(display_short) psi-mi:mtr1l_mouse(display_long)|uniprotkb:G protein-coupled receptor 50(gene name synonym)|uniprotkb:H9(gene name synonym)|uniprotkb:Gpr50(gene name)|psi-mi:Gpr50(display_short) psi-mi:"MI:0018"(two hybrid) Li et al. (2010) pubmed:21858214|imex:IM-26972 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21227924|imex:IM-26972-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_081274.2|ensembl:ENSMUSG00000005656(gene)|ensembl:ENSMUST00000005798(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028657|interpro:IPR036871|interpro:IPR042136|mint:Q6P8X1 refseq:NP_034470.1|refseq:NP_001295430.1|ensembl:ENSMUSG00000056380(gene)|ensembl:ENSMUST00000070449(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002280(Melatonin-related receptor type 1X)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - comment:mint|function:May be involved in several stages of intracellular trafficking - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/03/01 2019/03/01 rogid:RwXaINdRkGvsfz3rn4UT00VXECE10090 rogid:4OuzkWmEI6nBCumKxkfBrcN3FGs10090 rigid:7XpXlTf6fvd+IbmItJNIQczATtk false - sufficient binding region:303-591 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WV04 uniprotkb:O88495 intact:EBI-21227932|ensembl:ENSMUSP00000082016|uniprotkb:E9QMT7|uniprotkb:O35070 intact:EBI-21227860|uniprotkb:Q3V1S8|ensembl:ENSMUSP00000064608 psi-mi:kif9_mouse(display_long)|uniprotkb:Kif9(gene name)|psi-mi:Kif9(display_short) psi-mi:mtr1l_mouse(display_long)|uniprotkb:G protein-coupled receptor 50(gene name synonym)|uniprotkb:H9(gene name synonym)|uniprotkb:Gpr50(gene name)|psi-mi:Gpr50(display_short) psi-mi:"MI:0018"(two hybrid) Li et al. (2010) pubmed:21858214|imex:IM-26972 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21227963|imex:IM-26972-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032489(gene)|ensembl:ENSMUST00000084952(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031982"(vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:1903008"(organelle disassembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-MMU-2132295|reactome:R-MMU-6811434|reactome:R-MMU-983189|refseq:NP_034758.2 refseq:NP_034470.1|refseq:NP_001295430.1|ensembl:ENSMUSG00000056380(gene)|ensembl:ENSMUST00000070449(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002280(Melatonin-related receptor type 1X)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/03/01 2019/03/01 rogid:2Hesf7K9v+2DCCCq3rj5V76DV3w10090 rogid:4OuzkWmEI6nBCumKxkfBrcN3FGs10090 rigid:kpveZS8U9NXQeiTquiCxo+pHnbM false - sufficient binding region:303-591 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O88845 uniprotkb:O88495 intact:EBI-645773|uniprotkb:Q5SUB5|uniprotkb:Q5SUB7|uniprotkb:Q7TPE7|uniprotkb:Q8BQL6|ensembl:ENSMUSP00000099710 intact:EBI-21227860|uniprotkb:Q3V1S8|ensembl:ENSMUSP00000064608 psi-mi:aka10_mouse(display_long)|uniprotkb:Protein kinase A-anchoring protein 10(gene name synonym)|uniprotkb:Dual specificity A kinase-anchoring protein 2(gene name synonym)|uniprotkb:Akap10(gene name)|psi-mi:Akap10(display_short) psi-mi:mtr1l_mouse(display_long)|uniprotkb:G protein-coupled receptor 50(gene name synonym)|uniprotkb:H9(gene name synonym)|uniprotkb:Gpr50(gene name)|psi-mi:Gpr50(display_short) psi-mi:"MI:0018"(two hybrid) Li et al. (2010) pubmed:21858214|imex:IM-26972 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21227969|imex:IM-26972-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064305.2|ensembl:ENSMUSG00000047804(gene)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008104"(protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR036305|interpro:IPR037719|mint:O88845|reactome:R-MMU-983231|ensembl:ENSMUST00000102650(transcript) refseq:NP_034470.1|refseq:NP_001295430.1|ensembl:ENSMUSG00000056380(gene)|ensembl:ENSMUST00000070449(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002280(Melatonin-related receptor type 1X)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/03/01 2019/03/01 rogid:07HJ8UTUEOj2VvPiGvZHweTtWS810090 rogid:4OuzkWmEI6nBCumKxkfBrcN3FGs10090 rigid:UHC2IcZ5g+OUxbfHPjK9xKYIPL0 false - sufficient binding region:303-591 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55098 uniprotkb:O88495 intact:EBI-309466|uniprotkb:O35467 intact:EBI-21227860|uniprotkb:Q3V1S8|ensembl:ENSMUSP00000064608 psi-mi:pex2_mouse(display_long)|uniprotkb:Pex2(gene name)|psi-mi:Pex2(display_short)|uniprotkb:Paf1(gene name synonym)|uniprotkb:Pxmp3(gene name synonym)|uniprotkb:Pmp35(gene name synonym)|uniprotkb:Peroxin-2(gene name synonym)|uniprotkb:Peroxisomal membrane protein 3(gene name synonym)|uniprotkb:Peroxisome assembly factor 1(gene name synonym) psi-mi:mtr1l_mouse(display_long)|uniprotkb:G protein-coupled receptor 50(gene name synonym)|uniprotkb:H9(gene name synonym)|uniprotkb:Gpr50(gene name)|psi-mi:Gpr50(display_short) psi-mi:"MI:0018"(two hybrid) Li et al. (2010) pubmed:21858214|imex:IM-26972 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21227975|imex:IM-26972-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001156773.1|refseq:NP_001156774.1|refseq:NP_001156777.1|refseq:NP_001156778.1|refseq:NP_033020.2|interpro:IPR006845(Pex, N-terminal)|interpro:IPR018957|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|refseq:XP_006530121.1|refseq:XP_006530122.1|refseq:XP_011246442.1|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031648"(protein destabilization)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|refseq:NP_001254643.1|refseq:NP_001254644.1|refseq:XP_017174994.1 refseq:NP_034470.1|refseq:NP_001295430.1|ensembl:ENSMUSG00000056380(gene)|ensembl:ENSMUST00000070449(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002280(Melatonin-related receptor type 1X)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/03/01 2019/03/01 rogid:HC4cNe/NtDvZ6iaAl1Ir/zWVCbQ10090 rogid:4OuzkWmEI6nBCumKxkfBrcN3FGs10090 rigid:QYG1qI5W5C7AUrFUyZqjvP7agSY false - sufficient binding region:303-591 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VDV7 uniprotkb:O88495 intact:EBI-21396764|ensembl:ENSMUSP00000040585 intact:EBI-21227860|uniprotkb:Q3V1S8|ensembl:ENSMUSP00000064608 psi-mi:q8vdv7_mouse(display_long)|uniprotkb:Tbc1d19(gene name)|psi-mi:Tbc1d19(display_short) psi-mi:mtr1l_mouse(display_long)|uniprotkb:G protein-coupled receptor 50(gene name synonym)|uniprotkb:H9(gene name synonym)|uniprotkb:Gpr50(gene name)|psi-mi:Gpr50(display_short) psi-mi:"MI:0018"(two hybrid) Li et al. (2010) pubmed:21858214|imex:IM-26972 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21396774|imex:IM-26972-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039178(gene)|ensembl:ENSMUST00000037337(transcript)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|interpro:IPR042507|refseq:NP_653100.1 refseq:NP_034470.1|refseq:NP_001295430.1|ensembl:ENSMUSG00000056380(gene)|ensembl:ENSMUST00000070449(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002280(Melatonin-related receptor type 1X)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/03/01 2019/05/01 rogid:/P4FGQXvZBu6a8dHGxdG/0Altw810090 rogid:4OuzkWmEI6nBCumKxkfBrcN3FGs10090 rigid:Tvmo0A7Hl6Scbzk3LwCTlYAd7wY false - sufficient binding region:303-591 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8CHK4 uniprotkb:O88495 intact:EBI-1169948|uniprotkb:Q8CGZ3|uniprotkb:Q8CGZ4|uniprotkb:Q8VIH0|uniprotkb:A1L394|ensembl:ENSMUSP00000109271 intact:EBI-21227860|uniprotkb:Q3V1S8|ensembl:ENSMUSP00000064608 psi-mi:kat5_mouse(display_long)|uniprotkb:Kat5(gene name)|psi-mi:Kat5(display_short)|uniprotkb:Htatip(gene name synonym)|uniprotkb:Tip60(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym) psi-mi:mtr1l_mouse(display_long)|uniprotkb:G protein-coupled receptor 50(gene name synonym)|uniprotkb:H9(gene name synonym)|uniprotkb:Gpr50(gene name)|psi-mi:Gpr50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Li et al. (2010) pubmed:21858214|imex:IM-26972 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21228022|imex:IM-26972-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186176.1|refseq:NP_001186177.1|refseq:NP_848752.1|ensembl:ENSMUST00000113641(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|ensembl:ENSMUSG00000024926(gene)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|mint:Q8CHK4|reactome:R-MMU-2559586|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693548|reactome:R-MMU-5693565|reactome:R-MMU-5693568|reactome:R-MMU-5693571|reactome:R-MMU-5693579|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-6804756|reactome:R-MMU-69473|reactome:R-MMU-9018519 refseq:NP_034470.1|refseq:NP_001295430.1|ensembl:ENSMUSG00000056380(gene)|ensembl:ENSMUST00000070449(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002280(Melatonin-related receptor type 1X)|interpro:IPR017452(GPCR, rhodopsin-like superfamily) - - - figure legend:Figure 1f,1g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2019/03/01 2019/03/01 rogid:HmCuP1tKkN1mA5x6VY8LlnwSfwY10090 rogid:4OuzkWmEI6nBCumKxkfBrcN3FGs10090 rigid:NXDg0OBSeDkaxrVdGOCrkSNeXUE false flag tag:?-? sufficient binding region:1-264|myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8CHK4 uniprotkb:O88495 intact:EBI-1169948|uniprotkb:Q8CGZ3|uniprotkb:Q8CGZ4|uniprotkb:Q8VIH0|uniprotkb:A1L394|ensembl:ENSMUSP00000109271 intact:EBI-21227860|uniprotkb:Q3V1S8|ensembl:ENSMUSP00000064608 psi-mi:kat5_mouse(display_long)|uniprotkb:Kat5(gene name)|psi-mi:Kat5(display_short)|uniprotkb:Htatip(gene name synonym)|uniprotkb:Tip60(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym) psi-mi:mtr1l_mouse(display_long)|uniprotkb:G protein-coupled receptor 50(gene name synonym)|uniprotkb:H9(gene name synonym)|uniprotkb:Gpr50(gene name)|psi-mi:Gpr50(display_short) psi-mi:"MI:0663"(confocal microscopy) Li et al. (2010) pubmed:21858214|imex:IM-26972 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-21228344|imex:IM-26972-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186176.1|refseq:NP_001186177.1|refseq:NP_848752.1|ensembl:ENSMUST00000113641(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|ensembl:ENSMUSG00000024926(gene)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|mint:Q8CHK4|reactome:R-MMU-2559586|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693548|reactome:R-MMU-5693565|reactome:R-MMU-5693568|reactome:R-MMU-5693571|reactome:R-MMU-5693579|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-6804756|reactome:R-MMU-69473|reactome:R-MMU-9018519|go:"GO:0048471"(perinuclear region of cytoplasm) refseq:NP_034470.1|refseq:NP_001295430.1|ensembl:ENSMUSG00000056380(gene)|ensembl:ENSMUST00000070449(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008502"(melatonin receptor activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000025(Melatonin receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002280(Melatonin-related receptor type 1X)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|go:"GO:0048471"(perinuclear region of cytoplasm) - - - figure legend:Figure 2a, 2b, 2c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2019/03/01 2019/03/04 rogid:HmCuP1tKkN1mA5x6VY8LlnwSfwY10090 rogid:4OuzkWmEI6nBCumKxkfBrcN3FGs10090 rigid:NXDg0OBSeDkaxrVdGOCrkSNeXUE false red fluorescent protein tag:n-n enhanced green fluorescent protein tag:c-c|sufficient binding region:303-591 - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)