#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:A6T926	uniprotkb:A6T926	intact:EBI-21944879|ensemblbacteria:ABR77097	intact:EBI-21944879|ensemblbacteria:ABR77097	psi-mi:a6t926_klep7(display_long)|uniprotkb:KPN_01666(orf name)	psi-mi:a6t926_klep7(display_long)|uniprotkb:KPN_01666(orf name)	psi-mi:"MI:0114"(x-ray crystallography)	French et al. (2011)	imex:IM-27429|pubmed:21795808	taxid:272620(klep7)|taxid:272620("Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)")	taxid:272620(klep7)|taxid:272620("Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21944891|pdbe:3qva|imex:IM-27429-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3QVA|interpro:IPR014306(Hydroxyisourate hydrolase)|interpro:IPR023418|interpro:IPR023416|interpro:IPR036817|refseq:WP_002904788.1|ensemblbacteria:ABR77097(transcript)|ensemblbacteria:KPN_01666(gene)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0033971"(hydroxyisourate hydrolase activity)	rcsb pdb:3QVA|interpro:IPR014306(Hydroxyisourate hydrolase)|interpro:IPR023418|interpro:IPR023416|interpro:IPR036817|refseq:WP_002904788.1|ensemblbacteria:ABR77097(transcript)|ensemblbacteria:KPN_01666(gene)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0033971"(hydroxyisourate hydrolase activity)	-	-	-	figure legend:Fig.2, table 1|3d-resolution:1.76A|3d-r-factors:Rwork=19.8  Rfree=22.2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/08/01	2019/10/11	rogid:KQZli0BOiPtH47YnnaNlCZTUoIE272620	rogid:KQZli0BOiPtH47YnnaNlCZTUoIE272620	rigid:EOUH82wXvU+T3JKPQFboCFR4uRI	false	sufficient binding region:1-108	sufficient binding region:1-108	4	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:18072"	uniprotkb:A6T926	intact:EBI-25467608|chebi:"CHEBI:12137"|chebi:"CHEBI:2074"|chebi:"CHEBI:20588"	intact:EBI-21944879|ensemblbacteria:ABR77097	psi-mi:5-hydroxyisouric acid(display_short)|psi-mi:"CHEBI:18072"(display_long)|intact:5-Hydroxyisourate(synonym)|intact:5-hydroxyisourate(synonym)|intact:"5-hydroxy-5,7-dihydro-1H-purine-2,6,8(9H)-trione"(iupac name)	psi-mi:a6t926_klep7(display_long)|uniprotkb:KPN_01666(orf name)	psi-mi:"MI:0415"(enzymatic study)	French et al. (2011)	imex:IM-27429|pubmed:21795808	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:272620(klep7)|taxid:272620("Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)")	psi-mi:"MI:0210"(hydroxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25467605|imex:IM-27429-2	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	rcsb pdb:3QVA|interpro:IPR014306(Hydroxyisourate hydrolase)|interpro:IPR023418|interpro:IPR023416|interpro:IPR036817|refseq:WP_002904788.1|ensemblbacteria:ABR77097(transcript)|ensemblbacteria:KPN_01666(gene)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0033971"(hydroxyisourate hydrolase activity)	-	-	-	figure legend:Fig.1, Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kcat:172.0 ~2.0(second -1)|km:103.0x10^-6 ~2.0(molar)	2019/08/01	2020/03/10	-	rogid:KQZli0BOiPtH47YnnaNlCZTUoIE272620	-	false	-	sufficient binding region:1-108|mutation decreasing interaction rate:7-7|mutation decreasing interaction rate:41-41|mutation decreasing interaction rate:92-92|mutation decreasing interaction rate:108-108	2	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)