#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P28223	uniprotkb:P14416	intact:EBI-6656333|ensembl:ENSP00000437737|uniprotkb:B2RAC5|uniprotkb:B4DZ79|uniprotkb:F5GWE8|uniprotkb:Q5T8C0	intact:EBI-2928178|ensembl:ENSP00000354859|ensembl:ENSP00000442172|uniprotkb:Q9NZR3|uniprotkb:Q9UPA9	psi-mi:5ht2a_human(display_long)|uniprotkb:HTR2A(gene name)|psi-mi:HTR2A(display_short)|uniprotkb:HTR2(gene name synonym)|uniprotkb:Serotonin receptor 2A(gene name synonym)	psi-mi:drd2_human(display_long)|uniprotkb:DRD2(gene name)|psi-mi:DRD2(display_short)|uniprotkb:Dopamine D2 receptor(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Borroto-Escuela et al. (2010)	pubmed:20888323|imex:IM-27062	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21447624|imex:IM-27062-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102468(gene)|ensembl:ENST00000542664(transcript)|go:"GO:0001587"(Gq/11-coupled serotonin receptor activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007568"(aging)|go:"GO:0007613"(memory)|go:"GO:0008219"(cell death)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014824"(artery smooth muscle contraction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030431"(sleep)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044380"(protein localization to cytoskeleton)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0007208"(phospholipase C-activating serotonin receptor signaling pathway)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0007210"(serotonin receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070852"(cell body fiber)|go:"GO:0071886"("1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding")|go:"GO:0098664"(G protein-coupled serotonin receptor signaling pathway)|go:"GO:0098666"(G protein-coupled serotonin receptor complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000455(5-Hydroxytryptamine 2A receptor)|interpro:IPR002231(5-Hydroxytryptamine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|reactome:R-HSA-390666|reactome:R-HSA-416476|go:"GO:0051378"(serotonin binding)|refseq:NP_000612.1|refseq:NP_001159419.1|dip:DIP-41844N	ensembl:ENSG00000149295(gene)|ensembl:ENST00000362072(transcript)|ensembl:ENST00000542968(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001591"(dopamine neurotransmitter receptor activity, coupled via Gi/Go)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006914"(autophagy)|go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007616"(long-term memory)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010039"(response to iron ion)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014854"(response to inactivity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0021756"(striatum development)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0021853"(cerebral cortex GABAergic interneuron migration)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031223"(auditory behavior)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034776"(response to histamine)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042220"(response to cocaine)|go:"GO:0042321"(negative regulation of circadian sleep/wake cycle, sleep)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042493"|go:"GO:0042756"(drinking behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0033602"(negative regulation of dopamine secretion)|go:"GO:0043204"(perikaryon)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0043278"(response to morphine)|go:"GO:0043473"(pigmentation)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046717"(acid secretion)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048678"(response to axon injury)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051584"(regulation of dopamine uptake involved in synaptic transmission)|go:"GO:0051586"(positive regulation of dopamine uptake involved in synaptic transmission)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0060160"(negative regulation of dopamine receptor signaling pathway)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0090325"(regulation of locomotion involved in locomotory behavior)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1900168"(positive regulation of glial cell-derived neurotrophic factor production)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1990384"(hyaloid vascular plexus regression)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000929(Dopamine receptor)|interpro:IPR001922(Dopamine D2 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P14416|rcsb pdb:1I15|rcsb pdb:5AER|rcsb pdb:6CM4|rcsb pdb:6LUQ|rcsb pdb:6VMS|rcsb pdb:7JVR|reactome:R-HSA-390651|go:"GO:0051823"(regulation of synapse structural plasticity)|refseq:NP_000786.1|refseq:NP_057658.2|refseq:XP_016872785.1|dip:DIP-5977N	go:"GO:0005886"(plasma membrane)|go:"GO:0005622"(intracellular anatomical structure)	-	-	figure legend:Supplementary  Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/05/07	2019/06/04	rogid:wwxBh+3zPyTL6rfTCnViWTHndzo9606	rogid:S5beCpwOapTeUXcS45WlU5ApKEI9606	rigid:Q2y0cGdf8D5K8zjd33g7R9hCiF8	false	green fluorescent protein tag:c-c	yellow fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P28223	uniprotkb:P14416	intact:EBI-6656333|ensembl:ENSP00000437737|uniprotkb:B2RAC5|uniprotkb:B4DZ79|uniprotkb:F5GWE8|uniprotkb:Q5T8C0	intact:EBI-2928178|ensembl:ENSP00000354859|ensembl:ENSP00000442172|uniprotkb:Q9NZR3|uniprotkb:Q9UPA9	psi-mi:5ht2a_human(display_long)|uniprotkb:HTR2A(gene name)|psi-mi:HTR2A(display_short)|uniprotkb:HTR2(gene name synonym)|uniprotkb:Serotonin receptor 2A(gene name synonym)	psi-mi:drd2_human(display_long)|uniprotkb:DRD2(gene name)|psi-mi:DRD2(display_short)|uniprotkb:Dopamine D2 receptor(gene name synonym)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Borroto-Escuela et al. (2010)	pubmed:20888323|imex:IM-27062	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-21447650|imex:IM-27062-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102468(gene)|ensembl:ENST00000542664(transcript)|go:"GO:0001587"(Gq/11-coupled serotonin receptor activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007568"(aging)|go:"GO:0007613"(memory)|go:"GO:0008219"(cell death)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010513"(positive regulation of phosphatidylinositol biosynthetic process)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014824"(artery smooth muscle contraction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030431"(sleep)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044380"(protein localization to cytoskeleton)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0007208"(phospholipase C-activating serotonin receptor signaling pathway)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0007210"(serotonin receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070852"(cell body fiber)|go:"GO:0071886"("1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding")|go:"GO:0098664"(G protein-coupled serotonin receptor signaling pathway)|go:"GO:0098666"(G protein-coupled serotonin receptor complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000455(5-Hydroxytryptamine 2A receptor)|interpro:IPR002231(5-Hydroxytryptamine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|reactome:R-HSA-390666|reactome:R-HSA-416476|go:"GO:0051378"(serotonin binding)|refseq:NP_000612.1|refseq:NP_001159419.1|dip:DIP-41844N	ensembl:ENSG00000149295(gene)|ensembl:ENST00000362072(transcript)|ensembl:ENST00000542968(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001591"(dopamine neurotransmitter receptor activity, coupled via Gi/Go)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006914"(autophagy)|go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007616"(long-term memory)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010039"(response to iron ion)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014854"(response to inactivity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0021756"(striatum development)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0021853"(cerebral cortex GABAergic interneuron migration)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031223"(auditory behavior)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034776"(response to histamine)|go:"GO:0035094"(response to nicotine)|go:"GO:0035240"(dopamine binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042220"(response to cocaine)|go:"GO:0042321"(negative regulation of circadian sleep/wake cycle, sleep)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042493"|go:"GO:0042756"(drinking behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0033602"(negative regulation of dopamine secretion)|go:"GO:0043204"(perikaryon)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0043278"(response to morphine)|go:"GO:0043473"(pigmentation)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046717"(acid secretion)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048678"(response to axon injury)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051584"(regulation of dopamine uptake involved in synaptic transmission)|go:"GO:0051586"(positive regulation of dopamine uptake involved in synaptic transmission)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0060160"(negative regulation of dopamine receptor signaling pathway)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0090325"(regulation of locomotion involved in locomotory behavior)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1900168"(positive regulation of glial cell-derived neurotrophic factor production)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1990384"(hyaloid vascular plexus regression)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000929(Dopamine receptor)|interpro:IPR001922(Dopamine D2 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P14416|rcsb pdb:1I15|rcsb pdb:5AER|rcsb pdb:6CM4|rcsb pdb:6LUQ|rcsb pdb:6VMS|rcsb pdb:7JVR|reactome:R-HSA-390651|go:"GO:0051823"(regulation of synapse structural plasticity)|refseq:NP_000786.1|refseq:NP_057658.2|refseq:XP_016872785.1|dip:DIP-5977N	go:"GO:0005886"(plasma membrane)|go:"GO:0005622"(intracellular anatomical structure)	-	-	figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2019/05/07	2019/06/04	rogid:wwxBh+3zPyTL6rfTCnViWTHndzo9606	rogid:S5beCpwOapTeUXcS45WlU5ApKEI9606	rigid:Q2y0cGdf8D5K8zjd33g7R9hCiF8	false	green fluorescent protein tag:c-c	renilla luciferase protein tag:c-c	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)