#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96HD1 uniprotkb:P35348-1 intact:EBI-713009|uniprotkb:Q6I9X5|uniprotkb:Q8NFT4|uniprotkb:Q9Y409|uniprotkb:A8MX90|uniprotkb:B2RAA9|ensembl:ENSP00000373322|ensembl:ENSP00000393643|ensembl:ENSP00000507127|ensembl:ENSP00000508358 intact:EBI-21288891|ensembl:ENSP00000276393|ensembl:ENSP00000369947 psi-mi:crel1_human(display_long)|uniprotkb:CRELD1(gene name)|psi-mi:CRELD1(display_short)|uniprotkb:CIRRIN(gene name synonym)|uniprotkb:Cysteine-rich with EGF-like domain protein 1(gene name synonym)|uniprotkb:UNQ188/PRO214(orf name) psi-mi:p35348-1(display_long)|uniprotkb:ADRA1A(gene name)|psi-mi:ADRA1A(display_short)|uniprotkb:ADRA1C(gene name synonym)|uniprotkb:Alpha-1A adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1C adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1c(gene name synonym)|uniprotkb:Alpha 1c-1(isoform synonym)|uniprotkb:"Alpha(1A-1)"(isoform synonym) psi-mi:"MI:0018"(two hybrid) Nishimune et al. (2009) pubmed:20508391|imex:IM-26937 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21288883|imex:IM-26937-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026887.1|refseq:NP_001070883.1|refseq:NP_056328.2|refseq:XP_016862664.1|ensembl:ENSG00000163703(gene)|ensembl:ENST00000383811(transcript)|ensembl:ENST00000452070(transcript)|ensembl:ENST00000682783(transcript)|ensembl:ENST00000684493(transcript)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR006212(Furin-like repeat)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR021852|mint:Q96HD1 ensembl:ENSG00000120907(gene)|ensembl:ENST00000276393(transcript)|ensembl:ENST00000380573(transcript)|intact:EBI-489756(isoform-parent) - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/03/19 2019/04/01 rogid:YCHTMCBYRLSWAJ4W+2lmt/EjUlQ9606 rogid:Y/tnIWKpCfP2lFJDTS69YGxDywg9606 rigid:uFlJzlo7HjY7q1gxtbOxB+/WQuI false sufficient binding region:211-420 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96HD1 uniprotkb:P35348-1 intact:EBI-713009|uniprotkb:Q6I9X5|uniprotkb:Q8NFT4|uniprotkb:Q9Y409|uniprotkb:A8MX90|uniprotkb:B2RAA9|ensembl:ENSP00000373322|ensembl:ENSP00000393643|ensembl:ENSP00000507127|ensembl:ENSP00000508358 intact:EBI-21288891|ensembl:ENSP00000276393|ensembl:ENSP00000369947 psi-mi:crel1_human(display_long)|uniprotkb:CRELD1(gene name)|psi-mi:CRELD1(display_short)|uniprotkb:CIRRIN(gene name synonym)|uniprotkb:Cysteine-rich with EGF-like domain protein 1(gene name synonym)|uniprotkb:UNQ188/PRO214(orf name) psi-mi:p35348-1(display_long)|uniprotkb:ADRA1A(gene name)|psi-mi:ADRA1A(display_short)|uniprotkb:ADRA1C(gene name synonym)|uniprotkb:Alpha-1A adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1C adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1c(gene name synonym)|uniprotkb:Alpha 1c-1(isoform synonym)|uniprotkb:"Alpha(1A-1)"(isoform synonym) psi-mi:"MI:0018"(two hybrid) Nishimune et al. (2009) pubmed:20508391|imex:IM-26937 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21288913|imex:IM-26937-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026887.1|refseq:NP_001070883.1|refseq:NP_056328.2|refseq:XP_016862664.1|ensembl:ENSG00000163703(gene)|ensembl:ENST00000383811(transcript)|ensembl:ENST00000452070(transcript)|ensembl:ENST00000682783(transcript)|ensembl:ENST00000684493(transcript)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR006212(Furin-like repeat)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR021852|mint:Q96HD1 ensembl:ENSG00000120907(gene)|ensembl:ENST00000276393(transcript)|ensembl:ENST00000380573(transcript)|intact:EBI-489756(isoform-parent) - - - figure legend:Figure 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/03/19 2019/04/01 rogid:YCHTMCBYRLSWAJ4W+2lmt/EjUlQ9606 rogid:Y/tnIWKpCfP2lFJDTS69YGxDywg9606 rigid:uFlJzlo7HjY7q1gxtbOxB+/WQuI false sufficient binding region:244-420|necessary binding region:407-420,244-289 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96HD1 uniprotkb:P35348-1 intact:EBI-713009|uniprotkb:Q6I9X5|uniprotkb:Q8NFT4|uniprotkb:Q9Y409|uniprotkb:A8MX90|uniprotkb:B2RAA9|ensembl:ENSP00000373322|ensembl:ENSP00000393643|ensembl:ENSP00000507127|ensembl:ENSP00000508358 intact:EBI-21288891|ensembl:ENSP00000276393|ensembl:ENSP00000369947 psi-mi:crel1_human(display_long)|uniprotkb:CRELD1(gene name)|psi-mi:CRELD1(display_short)|uniprotkb:CIRRIN(gene name synonym)|uniprotkb:Cysteine-rich with EGF-like domain protein 1(gene name synonym)|uniprotkb:UNQ188/PRO214(orf name) psi-mi:p35348-1(display_long)|uniprotkb:ADRA1A(gene name)|psi-mi:ADRA1A(display_short)|uniprotkb:ADRA1C(gene name synonym)|uniprotkb:Alpha-1A adrenoreceptor(gene name synonym)|uniprotkb:Alpha-1C adrenergic receptor(gene name synonym)|uniprotkb:Alpha-adrenergic receptor 1c(gene name synonym)|uniprotkb:Alpha 1c-1(isoform synonym)|uniprotkb:"Alpha(1A-1)"(isoform synonym) psi-mi:"MI:0018"(two hybrid) Nishimune et al. (2009) pubmed:20508391|imex:IM-26937 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21288939|imex:IM-26937-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001026887.1|refseq:NP_001070883.1|refseq:NP_056328.2|refseq:XP_016862664.1|ensembl:ENSG00000163703(gene)|ensembl:ENST00000383811(transcript)|ensembl:ENST00000452070(transcript)|ensembl:ENST00000682783(transcript)|ensembl:ENST00000684493(transcript)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR006212(Furin-like repeat)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR021852|mint:Q96HD1 ensembl:ENSG00000120907(gene)|ensembl:ENST00000276393(transcript)|ensembl:ENST00000380573(transcript)|intact:EBI-489756(isoform-parent) - - - figure legend:Figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/03/19 2019/04/01 rogid:YCHTMCBYRLSWAJ4W+2lmt/EjUlQ9606 rogid:Y/tnIWKpCfP2lFJDTS69YGxDywg9606 rigid:uFlJzlo7HjY7q1gxtbOxB+/WQuI false sufficient binding region:244-420 necessary binding region:212-272|sufficient binding region:21-272 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)